-
1
-
-
0037232580
-
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
-
Kenney AM, Cole MD, Rowitch DH. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 2003;130:15-28.
-
(2003)
Development
, vol.130
, pp. 15-28
-
-
Kenney, A.M.1
Cole, M.D.2
Rowitch, D.H.3
-
2
-
-
45549091581
-
Medulloblastoma stem cells
-
Fan X, Eberhart CG. Medulloblastoma stem cells. J Clin Oncol 2008;26:2821-7.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2821-2827
-
-
Fan, X.1
Eberhart, C.G.2
-
3
-
-
0037223273
-
Medulloblastoma in mice lacking p53 and PARP: All roads lead to Gli
-
Eberhart CG. Medulloblastoma in mice lacking p53 and PARP: all roads lead to Gli. Am J Pathol 2003;162:7-10.
-
(2003)
Am J Pathol
, vol.162
, pp. 7-10
-
-
Eberhart, C.G.1
-
4
-
-
0026513426
-
Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis
-
Cogen PH, Daneshvar L, Metzger AK, Duyk G, Edwards MS, Sheffield VC. Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis. Am J Human Genet 1992;50:584-9.
-
(1992)
Am J Human Genet
, vol.50
, pp. 584-589
-
-
Cogen, P.H.1
Daneshvar, L.2
Metzger, A.K.3
Duyk, G.4
Edwards, M.S.5
Sheffield, V.C.6
-
5
-
-
0035445646
-
Clinical and molecular stratification of disease risk in medulloblastoma
-
Gilbertson R, Wickramasinghe C, Hernan R, et al. Clinical and molecular stratification of disease risk in medulloblastoma. Br J Cancer 2001;85:705-12.
-
(2001)
Br J Cancer
, vol.85
, pp. 705-712
-
-
Gilbertson, R.1
Wickramasinghe, C.2
Hernan, R.3
-
6
-
-
3242722919
-
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
-
Di Marcotullio L, Ferretti E, De Smaele E, et al. REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Proc Natl Acad Sci U S A 2004;101:10833-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10833-10838
-
-
Di Marcotullio, L.1
Ferretti, E.2
De Smaele, E.3
-
7
-
-
27544434763
-
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
-
Chen WY, Wang DH, Yen RC, Luo J, Gu W, Baylin SB. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005;123:437-48.
-
(2005)
Cell
, vol.123
, pp. 437-448
-
-
Chen, W.Y.1
Wang, D.H.2
Yen, R.C.3
Luo, J.4
Gu, W.5
Baylin, S.B.6
-
8
-
-
0030669218
-
Math1 is essential for genesis of cerebellar granule neurons
-
Ben-Arie N, Bellen HJ, Armstrong DL, et al. Math1 is essential for genesis of cerebellar granule neurons. Nature 1997;390:169-72.
-
(1997)
Nature
, vol.390
, pp. 169-172
-
-
Ben-Arie, N.1
Bellen, H.J.2
Armstrong, D.L.3
-
9
-
-
41149154521
-
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma
-
Briggs KJ, Corcoran-Schwartz IM, Zhang W, et al. Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. Genes Dev 2008;22:770-85.
-
(2008)
Genes Dev
, vol.22
, pp. 770-785
-
-
Briggs, K.J.1
Corcoran-Schwartz, I.M.2
Zhang, W.3
-
10
-
-
0142074790
-
Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice
-
Kim JY, Nelson AL, Algon SA, et al. Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Dev Biol 2003;263:50-66.
-
(2003)
Dev Biol
, vol.263
, pp. 50-66
-
-
Kim, J.Y.1
Nelson, A.L.2
Algon, S.A.3
-
11
-
-
8544260349
-
Interferon-γ induced medulloblastoma in the developing cerebellum
-
Lin W, Kemper A, McCarthy KD, et al. Interferon-γ induced medulloblastoma in the developing cerebellum. J Neurosci 2004;24:10074-83.
-
(2004)
J Neurosci
, vol.24
, pp. 10074-10083
-
-
Lin, W.1
Kemper, A.2
McCarthy, K.D.3
-
12
-
-
21044435675
-
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma
-
Oliver TG, Read TA, Kessler JD, et al. Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma. Development 2005;132:2425-39.
-
(2005)
Development
, vol.132
, pp. 2425-2439
-
-
Oliver, T.G.1
Read, T.A.2
Kessler, J.D.3
-
13
-
-
34547414651
-
Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1
-
Salsano E, Croci L, Maderna E, et al. Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1. Neuro-Oncol 2007;9:298-307.
-
(2007)
Neuro-Oncol
, vol.9
, pp. 298-307
-
-
Salsano, E.1
Croci, L.2
Maderna, E.3
-
14
-
-
0029014425
-
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
-
Wales MM, Biel MA, el Deiry W, et al. p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med 1995;1:570-7.
-
(1995)
Nat Med
, vol.1
, pp. 570-577
-
-
Wales, M.M.1
Biel, M.A.2
el Deiry, W.3
-
15
-
-
2542580146
-
Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1
-
Pinte S, Guerardel C, Deltour-Balerdi S, Godwin AK, Leprince D. Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1. Oncogene 2004;23:4023-31.
-
(2004)
Oncogene
, vol.23
, pp. 4023-4031
-
-
Pinte, S.1
Guerardel, C.2
Deltour-Balerdi, S.3
Godwin, A.K.4
Leprince, D.5
-
16
-
-
0035870280
-
Epigenetic patterns in the progression of esophageal adenocarcinoma
-
Eads CA, Lord RV, Wickramasinghe K, et al. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res 2001;61:3410-8.
-
(2001)
Cancer Res
, vol.61
, pp. 3410-3418
-
-
Eads, C.A.1
Lord, R.V.2
Wickramasinghe, K.3
-
17
-
-
0032559995
-
Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer
-
Fujii H, Biel MA, Zhou W, Weitzman SA, Baylin SB, Gabrielson E. Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer. Oncogene 1998;16:2159-64.
-
(1998)
Oncogene
, vol.16
, pp. 2159-2164
-
-
Fujii, H.1
Biel, M.A.2
Zhou, W.3
Weitzman, S.A.4
Baylin, S.B.5
Gabrielson, E.6
-
18
-
-
0030909701
-
DNA methylation changes in hematologic malignancies: Biologic and clinical implications
-
Issa JP, Baylin SB, Herman JG. DNA methylation changes in hematologic malignancies: biologic and clinical implications. Leukemia 1997;11 Suppl 1:S7-11.
-
(1997)
Leukemia
, vol.11
, Issue.SUPPL. 1
-
-
Issa, J.P.1
Baylin, S.B.2
Herman, J.G.3
-
19
-
-
0033052844
-
DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis
-
Kanai Y, Hui AM, Sun L, et al. DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis. Hepatology 1999;29:703-9.
-
(1999)
Hepatology
, vol.29
, pp. 703-709
-
-
Kanai, Y.1
Hui, A.M.2
Sun, L.3
-
20
-
-
0032498296
-
DNA hypermethylation at the D17S5 locus is associated with gastric carcinogenesis
-
Kanai Y, Ushijima S, Ochiai A, Eguchi K, Hui A, Hirohashi S. DNA hypermethylation at the D17S5 locus is associated with gastric carcinogenesis. Cancer Lett 1998;122:135-41.
-
(1998)
Cancer Lett
, vol.122
, pp. 135-141
-
-
Kanai, Y.1
Ushijima, S.2
Ochiai, A.3
Eguchi, K.4
Hui, A.5
Hirohashi, S.6
-
21
-
-
0033179375
-
Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
-
Melki JR, Vincent PC, Clark SJ. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 1999;59:3730-40.
-
(1999)
Cancer Res
, vol.59
, pp. 3730-3740
-
-
Melki, J.R.1
Vincent, P.C.2
Clark, S.J.3
-
22
-
-
0035099160
-
Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes
-
Strathdee G, Appleton K, Illand M, et al. Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes. Am J Pathol 2001;158:1121-7.
-
(2001)
Am J Pathol
, vol.158
, pp. 1121-1127
-
-
Strathdee, G.1
Appleton, K.2
Illand, M.3
-
23
-
-
2442535041
-
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling
-
Lindsey JC, Lusher ME, Anderton JA, et al. Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling. Carcinogenesis 2004;25:661-8.
-
(2004)
Carcinogenesis
, vol.25
, pp. 661-668
-
-
Lindsey, J.C.1
Lusher, M.E.2
Anderton, J.A.3
-
24
-
-
0036644901
-
Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma
-
Rood BR, Zhang H, Weitman DM, Cogen PH. Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma. Cancer Res 2002;62:3794-7.
-
(2002)
Cancer Res
, vol.62
, pp. 3794-3797
-
-
Rood, B.R.1
Zhang, H.2
Weitman, D.M.3
Cogen, P.H.4
-
25
-
-
0242609163
-
Epigenetic silencing of the HIC-1 gene in human medulloblastomas
-
Waha A, Koch A, Meyer-Puttlitz B, et al. Epigenetic silencing of the HIC-1 gene in human medulloblastomas. J Neuropathol Exp Neurol 2003;62:1192-201.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 1192-1201
-
-
Waha, A.1
Koch, A.2
Meyer-Puttlitz, B.3
-
26
-
-
1542347188
-
Analysis of cerebellar development in math1 null embryos and chimeras
-
Jensen P, Smeyne R, Goldwitz D. Analysis of cerebellar development in math1 null embryos and chimeras. J Neurosci 2004;24:2202-11.
-
(2004)
J Neurosci
, vol.24
, pp. 2202-2211
-
-
Jensen, P.1
Smeyne, R.2
Goldwitz, D.3
-
27
-
-
0032796826
-
Sonic hedgehog regulates the growth and patterning of the cerebellum
-
Dahmane N, Ruiz-i-Altaba A. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 1999;126:3089-100.
-
(1999)
Development
, vol.126
, pp. 3089-3100
-
-
Dahmane, N.1
Ruiz-i-Altaba, A.2
-
28
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich LV, Milenkovic L, Higgins KM, Scott MP. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 1997;277:1109-13.
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
29
-
-
41149130332
-
Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development
-
Zhao H, Ayrault O, Zindy F, Kim JH, Roussel MF. Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development. Genes Dev 2008;22:722-7.
-
(2008)
Genes Dev
, vol.22
, pp. 722-727
-
-
Zhao, H.1
Ayrault, O.2
Zindy, F.3
Kim, J.H.4
Roussel, M.F.5
-
30
-
-
33746565431
-
Lineage dependency and lineage-survival oncogenes in human cancer
-
Garraway LA, Sellers WR. Lineage dependency and lineage-survival oncogenes in human cancer. Nat Rev Cancer 2006;6:593-602.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 593-602
-
-
Garraway, L.A.1
Sellers, W.R.2
-
32
-
-
1442307700
-
Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway
-
Gazit R, Krizhanovsky V, Ben-Arie N. Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development 2004;131:903-13.
-
(2004)
Development
, vol.131
, pp. 903-913
-
-
Gazit, R.1
Krizhanovsky, V.2
Ben-Arie, N.3
-
33
-
-
0034883005
-
Cytogenetic responses in high risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2′-deoxyazacytidine
-
Lubbert M, Wijermans P, Kunzmann R, et al. Cytogenetic responses in high risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2′-deoxyazacytidine. Br J Haematol 2001;114:349-57.
-
(2001)
Br J Haematol
, vol.114
, pp. 349-357
-
-
Lubbert, M.1
Wijermans, P.2
Kunzmann, R.3
-
34
-
-
33846057945
-
Induction of complete remission in a patient with acute myeloid leukemia refractory to high dose chemotherapy through treatment with 5-azacytidine
-
Kuendgen A, Graf T, Zohren F, et al. Induction of complete remission in a patient with acute myeloid leukemia refractory to high dose chemotherapy through treatment with 5-azacytidine. Leuk Res 2007;31:407-9.
-
(2007)
Leuk Res
, vol.31
, pp. 407-409
-
-
Kuendgen, A.1
Graf, T.2
Zohren, F.3
|