-
2
-
-
0034523656
-
expression of erbB1, erbB2, P53 and amplification of erbB1, erbB2 and erbB3 in non-small cell lung cancer
-
Reinmuth N., Brandt B., Kunze W.P., Junker K., Thomas M., Achatzy R., et al. expression of erbB1, erbB2, P53 and amplification of erbB1, erbB2 and erbB3 in non-small cell lung cancer. Eur Respir J 16 (2000) 991-996
-
(2000)
Eur Respir J
, vol.16
, pp. 991-996
-
-
Reinmuth, N.1
Brandt, B.2
Kunze, W.P.3
Junker, K.4
Thomas, M.5
Achatzy, R.6
-
3
-
-
0037029712
-
Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas
-
Hirsch F.R., Varella-Garcia M., Franklin W.A., Veve R., Chen L., Helfrich B., et al. Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas. Br J Cancer 86 (2002) 1449-1456
-
(2002)
Br J Cancer
, vol.86
, pp. 1449-1456
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Franklin, W.A.3
Veve, R.4
Chen, L.5
Helfrich, B.6
-
4
-
-
0037667417
-
Preclinical studies with Erlotinib (Tarceva)
-
Akita R.W., and Sliwkowski M.X. Preclinical studies with Erlotinib (Tarceva). Semin Oncol 30 (2003) 15-24
-
(2003)
Semin Oncol
, vol.30
, pp. 15-24
-
-
Akita, R.W.1
Sliwkowski, M.X.2
-
5
-
-
22044445517
-
Erlotinib in previously treated non-small cell lung cancer
-
Shepherd F.A., Pereira J.R., Ciuleanu T.E., Tan E.H., Hirsh V., Thongprasert S., et al. Erlotinib in previously treated non-small cell lung cancer. N Engl J Med 353 (2005) 123-132
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Pereira, J.R.2
Ciuleanu, T.E.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
6
-
-
18344390418
-
ERBB receptors and cancer: the complexity of targeted inhibitors
-
Hynes N.E., and Lane H.A. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5 (2005) 341-354
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
7
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F., Hirsch F.R., Rossi E., Bartolini S., Ceresoli G.L., Bemis L., et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 97 (2005) 643-655
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
Bartolini, S.4
Ceresoli, G.L.5
Bemis, L.6
-
8
-
-
22044453790
-
Erlotinib in lung cancer--molecular and clinical predictors of outcome
-
Tsao M.-S., Sakurada A., Cutz J.-C., Zhu C.-Q., Kamel-Reid S., Squire J., et al. Erlotinib in lung cancer--molecular and clinical predictors of outcome. N Engl J Med 353 (2005) 133-144
-
(2005)
N Engl J Med
, vol.353
, pp. 133-144
-
-
Tsao, M.-S.1
Sakurada, A.2
Cutz, J.-C.3
Zhu, C.-Q.4
Kamel-Reid, S.5
Squire, J.6
-
9
-
-
23844490782
-
Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in Gefitinib-treated chemorefractory lung adenocarcinomas
-
Taron M., Ichinose Y., Rosell R., Mok T., Massuti B., Zamora L., et al. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in Gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 11 (2005) 5878-5885
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5878-5885
-
-
Taron, M.1
Ichinose, Y.2
Rosell, R.3
Mok, T.4
Massuti, B.5
Zamora, L.6
-
10
-
-
33745879131
-
Molecular determinants of response to RTK-targeting agents in nonsmall cell lung cancer
-
Reinmuth N., Meister M., Muley T., Steins M., Kreuter M., Herth F.J., et al. Molecular determinants of response to RTK-targeting agents in nonsmall cell lung cancer. Int J Cancer 119 (2006) 727-734
-
(2006)
Int J Cancer
, vol.119
, pp. 727-734
-
-
Reinmuth, N.1
Meister, M.2
Muley, T.3
Steins, M.4
Kreuter, M.5
Herth, F.J.6
-
11
-
-
15744372810
-
Primary resistance of lung adenocarcinomas to Gefitinib or Erlotinib
-
Pao W., Wang T.Y., Riely G.J., Miller V.A., Pan Q., Ladanyi M., et al. Primary resistance of lung adenocarcinomas to Gefitinib or Erlotinib. PLoS Med 2 (2005) e17
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
Miller, V.A.4
Pan, Q.5
Ladanyi, M.6
-
12
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350 (2004) 2129-2139
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
13
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R., Bell D.W., Haber D.A., and Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 305 (2004) 1163-1167
-
(2004)
Science
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
Settleman, J.4
-
14
-
-
14844366111
-
ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines.
-
Engelman J.A., Janne P.A., Mermel C., Pearlberg J., Mukohara T., Fleet C., et al. ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines. Proc Natl Acad Sci USA 102 (2005) 3788-3793
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3788-3793
-
-
Engelman, J.A.1
Janne, P.A.2
Mermel, C.3
Pearlberg, J.4
Mukohara, T.5
Fleet, C.6
-
15
-
-
0037429570
-
Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells
-
Akagi M., Kawaguchi M., Liu W., McCarty M.F., Takeda A., Fan F., et al. Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells. Br J Cancer 88 (2003) 796-802
-
(2003)
Br J Cancer
, vol.88
, pp. 796-802
-
-
Akagi, M.1
Kawaguchi, M.2
Liu, W.3
McCarty, M.F.4
Takeda, A.5
Fan, F.6
-
16
-
-
0035906852
-
Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway
-
Clarke K., Smith K., Gullick W.J., and Harris A.L. Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway. Br J Cancer 84 (2001) 1322-1329
-
(2001)
Br J Cancer
, vol.84
, pp. 1322-1329
-
-
Clarke, K.1
Smith, K.2
Gullick, W.J.3
Harris, A.L.4
-
17
-
-
0028114985
-
The implications of angiogenesis for the biology and therapy of cancer metastasis
-
Fidler I.J., and Ellis L.M. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 79 (1994) 185-188
-
(1994)
Cell
, vol.79
, pp. 185-188
-
-
Fidler, I.J.1
Ellis, L.M.2
-
18
-
-
55049106447
-
-
World Health Organization. Histological Typing of Lung Tumours. 3rd ed. Lyon: IARC Press; 2004.
-
World Health Organization. Histological Typing of Lung Tumours. 3rd ed. Lyon: IARC Press; 2004.
-
-
-
-
19
-
-
33847318214
-
Mutational status of the epidermal growth factor receptor (EGFR) gene in thymomas and thymic carcinomas
-
Meister M., Schirmacher P., Dienemann H., Mechtersheimer G., Schnabel P.A., Kern M.A., et al. Mutational status of the epidermal growth factor receptor (EGFR) gene in thymomas and thymic carcinomas. Cancer Lett 248 (2007) 186-191
-
(2007)
Cancer Lett
, vol.248
, pp. 186-191
-
-
Meister, M.1
Schirmacher, P.2
Dienemann, H.3
Mechtersheimer, G.4
Schnabel, P.A.5
Kern, M.A.6
-
20
-
-
0027537408
-
Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization
-
du Manoir S., Speicher M.R., Joos S., Schrock E., Popp S., Dohner H., et al. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Hum Genet 90 (1993) 590-610
-
(1993)
Hum Genet
, vol.90
, pp. 590-610
-
-
du Manoir, S.1
Speicher, M.R.2
Joos, S.3
Schrock, E.4
Popp, S.5
Dohner, H.6
-
21
-
-
0027966172
-
Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
-
Kallioniemi O.P., Kallioniemi A., Piper J., Isola J., Waldman F.M., Gray J.W., et al. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer 10 (1994) 231-243
-
(1994)
Genes Chromosomes Cancer
, vol.10
, pp. 231-243
-
-
Kallioniemi, O.P.1
Kallioniemi, A.2
Piper, J.3
Isola, J.4
Waldman, F.M.5
Gray, J.W.6
-
22
-
-
33845966075
-
Prognostic significance of vessel architecture and vascular stability in non-small cell lung cancer
-
Reinmuth N., Piegelbrock E., Raedel M., Fehrmann N., Hintelmann H., Wagner R., et al. Prognostic significance of vessel architecture and vascular stability in non-small cell lung cancer. Lung Cancer 55 (2007) 53-60
-
(2007)
Lung Cancer
, vol.55
, pp. 53-60
-
-
Reinmuth, N.1
Piegelbrock, E.2
Raedel, M.3
Fehrmann, N.4
Hintelmann, H.5
Wagner, R.6
-
23
-
-
0038271868
-
From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression
-
Schmidt-Kittler O., Ragg T., Daskalakis A., Granzow M., Ahr A., Blankenstein T.J., et al. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc Natl Acad Sci USA 100 (2003) 7737-7742
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7737-7742
-
-
Schmidt-Kittler, O.1
Ragg, T.2
Daskalakis, A.3
Granzow, M.4
Ahr, A.5
Blankenstein, T.J.6
-
24
-
-
33645241407
-
The RIN: an RNA integrity number for assigning integrity values to RNA measurements
-
Schroeder A., Mueller O., Stocker S., Salowsky R., Leiber M., Gassmann M., et al. The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol Biol 7 (2006) 3
-
(2006)
BMC Mol Biol
, vol.7
, pp. 3
-
-
Schroeder, A.1
Mueller, O.2
Stocker, S.3
Salowsky, R.4
Leiber, M.5
Gassmann, M.6
-
25
-
-
0036303333
-
Learning and evolutionary parameter optimization
-
Ragg T., and Bayesian. Learning and evolutionary parameter optimization. AI Commun 15 (2002) 61-74
-
(2002)
AI Commun
, vol.15
, pp. 61-74
-
-
Ragg, T.1
Bayesian2
-
26
-
-
33646402073
-
Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma
-
Matsumoto S., Iwakawa R., Kohno T., Suzuki K., Matsuno Y., Yamamoto S., et al. Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma. Int J Cancer 118 (2006) 2498-2504
-
(2006)
Int J Cancer
, vol.118
, pp. 2498-2504
-
-
Matsumoto, S.1
Iwakawa, R.2
Kohno, T.3
Suzuki, K.4
Matsuno, Y.5
Yamamoto, S.6
-
27
-
-
20044364933
-
EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
-
Marchetti A., Martella C., Felicioni L., Barassi F., Salvatore S., Chella A., et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 23 (2005) 857-865
-
(2005)
J Clin Oncol
, vol.23
, pp. 857-865
-
-
Marchetti, A.1
Martella, C.2
Felicioni, L.3
Barassi, F.4
Salvatore, S.5
Chella, A.6
-
28
-
-
26244466212
-
Cytogenetic differences in breast cancer samples between German and Japanese patients
-
Packeisen J., Nakachi K., Boecker W., Brandt B., and Buerger H. Cytogenetic differences in breast cancer samples between German and Japanese patients. J Clin Pathol 58 (2005) 1101-1103
-
(2005)
J Clin Pathol
, vol.58
, pp. 1101-1103
-
-
Packeisen, J.1
Nakachi, K.2
Boecker, W.3
Brandt, B.4
Buerger, H.5
-
29
-
-
26444568561
-
Chromosomal aberrations in follicular non-Hodgkin lymphomas of Japanese patients, detected with comparative genomic hybridization and polymerase chain reaction analysis
-
D'Haese J.G., Tsukasaki K., Cremer F.W., Fischer C., Bartram C.R., and Jauch A. Chromosomal aberrations in follicular non-Hodgkin lymphomas of Japanese patients, detected with comparative genomic hybridization and polymerase chain reaction analysis. Cancer Genet Cytogenet 162 (2005) 107-114
-
(2005)
Cancer Genet Cytogenet
, vol.162
, pp. 107-114
-
-
D'Haese, J.G.1
Tsukasaki, K.2
Cremer, F.W.3
Fischer, C.4
Bartram, C.R.5
Jauch, A.6
-
30
-
-
0036145144
-
Chromosomal imbalances of primary and metastatic lung adenocarcinomas
-
Goeze A., Schluns K., Wolf G., Thasler Z., Petersen S., and Petersen I. Chromosomal imbalances of primary and metastatic lung adenocarcinomas. J Pathol 196 (2002) 8-16
-
(2002)
J Pathol
, vol.196
, pp. 8-16
-
-
Goeze, A.1
Schluns, K.2
Wolf, G.3
Thasler, Z.4
Petersen, S.5
Petersen, I.6
-
31
-
-
0023194301
-
Relationship between gene amplification and chromosomal deviations in malignant human gliomas
-
Bigner S.H., Wong A.J., Mark J., Muhlbaier L.H., Kinzler K.W., Vogelstein B., et al. Relationship between gene amplification and chromosomal deviations in malignant human gliomas. Cancer Genet Cytogenet 29 (1987) 165-170
-
(1987)
Cancer Genet Cytogenet
, vol.29
, pp. 165-170
-
-
Bigner, S.H.1
Wong, A.J.2
Mark, J.3
Muhlbaier, L.H.4
Kinzler, K.W.5
Vogelstein, B.6
-
32
-
-
19944427851
-
Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer
-
Amann J., Kalyankrishna S., Massion P.P., Ohm J.E., Girard L., Shigematsu H., et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res 65 (2005) 226-235
-
(2005)
Cancer Res
, vol.65
, pp. 226-235
-
-
Amann, J.1
Kalyankrishna, S.2
Massion, P.P.3
Ohm, J.E.4
Girard, L.5
Shigematsu, H.6
-
33
-
-
24344435084
-
Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features
-
Shibata T., Uryu S., Kokubu A., Hosoda F., Ohki M., Sakiyama T., et al. Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features. Clin Cancer Res 11 (2005) 6177-6185
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6177-6185
-
-
Shibata, T.1
Uryu, S.2
Kokubu, A.3
Hosoda, F.4
Ohki, M.5
Sakiyama, T.6
-
34
-
-
0033594394
-
Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p
-
Sunwoo J.B., Sun P.C., Gupta V.K., Schmidt A.P., El-Mofty S., and Scholnick S.B. Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p. Oncogene 18 (1999) 2651-2655
-
(1999)
Oncogene
, vol.18
, pp. 2651-2655
-
-
Sunwoo, J.B.1
Sun, P.C.2
Gupta, V.K.3
Schmidt, A.P.4
El-Mofty, S.5
Scholnick, S.B.6
-
35
-
-
34848838572
-
Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer
-
Bullard R.S., Gibson W., Bose S.K., Belgrave J.K., Eaddy A.C., Wright C.J., et al. Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer. Mol Immunol 45 (2008) 839-848
-
(2008)
Mol Immunol
, vol.45
, pp. 839-848
-
-
Bullard, R.S.1
Gibson, W.2
Bose, S.K.3
Belgrave, J.K.4
Eaddy, A.C.5
Wright, C.J.6
-
36
-
-
0142188691
-
Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme
-
Shinojima N., Tada K., Shiraishi S., Kamiryo T., Kochi M., Nakamura H., et al. Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme. Cancer Res 63 (2003) 6962-6970
-
(2003)
Cancer Res
, vol.63
, pp. 6962-6970
-
-
Shinojima, N.1
Tada, K.2
Shiraishi, S.3
Kamiryo, T.4
Kochi, M.5
Nakamura, H.6
-
37
-
-
26644465742
-
Epidermal growth factor receptor expression status in lung cancer correlates with its mutation
-
Suzuki M., Shigematsu H., Hiroshima K., Iizasa T., Nakatani Y., Minna J.D., et al. Epidermal growth factor receptor expression status in lung cancer correlates with its mutation. Hum Pathol 36 (2005) 1127-1134
-
(2005)
Hum Pathol
, vol.36
, pp. 1127-1134
-
-
Suzuki, M.1
Shigematsu, H.2
Hiroshima, K.3
Iizasa, T.4
Nakatani, Y.5
Minna, J.D.6
-
38
-
-
14744281693
-
Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas. An immunohistochemical and fluorescence in situ hybridization study
-
Suzuki S., Dobashi Y., Sakurai H., Nishikawa K., Hanawa M., and Ooi A. Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas. An immunohistochemical and fluorescence in situ hybridization study. Cancer 103 (2005) 1265-1273
-
(2005)
Cancer
, vol.103
, pp. 1265-1273
-
-
Suzuki, S.1
Dobashi, Y.2
Sakurai, H.3
Nishikawa, K.4
Hanawa, M.5
Ooi, A.6
-
39
-
-
0034255151
-
Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases
-
Bruns C.J., Liu W., Davis D.W., Shaheen R.M., McConkey D.J., Wilson M.R., et al. Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases. Cancer 89 (2000) 488-499
-
(2000)
Cancer
, vol.89
, pp. 488-499
-
-
Bruns, C.J.1
Liu, W.2
Davis, D.W.3
Shaheen, R.M.4
McConkey, D.J.5
Wilson, M.R.6
-
40
-
-
20244381389
-
Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the Her-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer
-
Herbst R.S., Johnson D.H., Mininberg E., Carbone D.P., Henderson T., Kim E.S., et al. Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the Her-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer. J Clin Oncol 23 (2005) 2544-2555
-
(2005)
J Clin Oncol
, vol.23
, pp. 2544-2555
-
-
Herbst, R.S.1
Johnson, D.H.2
Mininberg, E.3
Carbone, D.P.4
Henderson, T.5
Kim, E.S.6
-
41
-
-
38949101107
-
Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification
-
Angulo B., Suarez-Gauthier A., Lopez-Rios F., Medina P., Conde E., Tang M., et al. Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification. J Pathol 214 (2007) 347-356
-
(2007)
J Pathol
, vol.214
, pp. 347-356
-
-
Angulo, B.1
Suarez-Gauthier, A.2
Lopez-Rios, F.3
Medina, P.4
Conde, E.5
Tang, M.6
|