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Volumn 68, Issue 16, 2008, Pages 2303-2324

Variceal bleeding: Pharmacological treatment and prophylactic strategies

Author keywords

Beta adrenergic receptor antagonists, therapeutic use; Gastrointestinal haemorrhage, treatment; Isosorbide mononitrate, therapeutic use; Octreotide, therapeutic use; Terlipressin, therapeutic use; Variceal haemorrhage, treatment

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIINFECTIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARVEDILOL; CLONIDINE; DIURETIC AGENT; ENDOTHELIN RECEPTOR ANTAGONIST; GLYCERYL TRINITRATE; IRBESARTAN; ISOSORBIDE MONONITRATE; LOSARTAN; NADOLOL; NITRIC ACID DERIVATIVE; NITRIC OXIDE DONOR; OCTREOTIDE; PRAZOSIN; PROPRANOLOL; SOMATOSTATIN; SOMATOSTATIN DERIVATIVE; SPIRONOLACTONE; TERLIPRESSIN; TIMOLOL; UNINDEXED DRUG; VAPREOTIDE; VASOACTIVE AGENT; VASOCONSTRICTOR AGENT; VASODILATOR AGENT; VASOPRESSIN; VASOPRESSIN DERIVATIVE;

EID: 55049093452     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/0003495-200868160-00004     Document Type: Review
Times cited : (33)

References (121)
  • 1
    • 0037343930 scopus 로고    scopus 로고
    • Improved patient survival after acute variceal bleeding: A multicenter, cohort study
    • Chalasani N, Kahi C, Francois F, et al. Improved patient survival after acute variceal bleeding: a multicenter, cohort study. Am J Gastroenterol 2003; 98: 653-9
    • (2003) Am J Gastroenterol , vol.98 , pp. 653-659
    • Chalasani, N.1    Kahi, C.2    Francois, F.3
  • 2
    • 4544261930 scopus 로고    scopus 로고
    • Improved survival after variceal bleeding in patients with cirrhosis over the past two decades
    • Carbonell N, Pauwels A, Serfaty L, et al. Improved survival after variceal bleeding in patients with cirrhosis over the past two decades. Hepatology 2004; 40: 652-9
    • (2004) Hepatology , vol.40 , pp. 652-659
    • Carbonell, N.1    Pauwels, A.2    Serfaty, L.3
  • 3
    • 0042322991 scopus 로고    scopus 로고
    • Upper digestive bleeding in cirrhosis: Post-therapeutic outcome and prognostic indicators
    • for the Cooperative Study group
    • D'Amico G, De Franchis R, for the Cooperative Study group. Upper digestive bleeding in cirrhosis: post-therapeutic outcome and prognostic indicators. Hepatology 2003; 38: 599-612
    • (2003) Hepatology , vol.38 , pp. 599-612
    • D'Amico, G.1    De Franchis, R.2
  • 4
    • 28844490547 scopus 로고    scopus 로고
    • Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies
    • D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006; 44: 217-31
    • (2006) J Hepatol , vol.44 , pp. 217-231
    • D'Amico, G.1    Garcia-Tsao, G.2    Pagliaro, L.3
  • 5
    • 0034843801 scopus 로고    scopus 로고
    • Natural history of portal hypertension in patients with cirrhosis
    • De Franchis R, Primignani M. Natural history of portal hypertension in patients with cirrhosis. Clin Liver Dis 2001; 5: 645-63
    • (2001) Clin Liver Dis , vol.5 , pp. 645-663
    • De Franchis, R.1    Primignani, M.2
  • 6
    • 28144455912 scopus 로고    scopus 로고
    • Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis
    • Groszmann RJ, Garcia-Tsao G, Bosch J, et al. Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med 2005; 353: 2254-61
    • (2005) N Engl J Med , vol.353 , pp. 2254-2261
    • Groszmann, R.J.1    Garcia-Tsao, G.2    Bosch, J.3
  • 7
    • 0033403318 scopus 로고    scopus 로고
    • Pharmacological treatment of portal hypertension: An evidence-based approach
    • D'Amico G, Pagliaro L, Bosch J. Pharmacological treatment of portal hypertension: an evidence-based approach. Semin Liver Dis 1999; 19: 475-505
    • (1999) Semin Liver Dis , vol.19 , pp. 475-505
    • D'Amico, G.1    Pagliaro, L.2    Bosch, J.3
  • 8
    • 0023681215 scopus 로고    scopus 로고
    • North Italian Endoscopic Club for the study and treatment of esophageal varices. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices: a prospective multicenter study. N Engl J Med 1988; 319: 983-9
    • North Italian Endoscopic Club for the study and treatment of esophageal varices. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices: a prospective multicenter study. N Engl J Med 1988; 319: 983-9
  • 9
    • 0023019354 scopus 로고
    • Hemodinamic factors involved in the development and rupture of esophageal varices: A pathophysiologic approach to treatment
    • Polio J, Groszmann RJ. Hemodinamic factors involved in the development and rupture of esophageal varices: a pathophysiologic approach to treatment. Semin Liver Dis 1986; 6: 318-31
    • (1986) Semin Liver Dis , vol.6 , pp. 318-331
    • Polio, J.1    Groszmann, R.J.2
  • 10
    • 0036154951 scopus 로고    scopus 로고
    • The paradox of nitric oxide in cirrhosis and portal hypertension: Too much, not enough
    • Wiest R, Gorszmann RJ. The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough. Hepatology 2002; 35: 478-91
    • (2002) Hepatology , vol.35 , pp. 478-491
    • Wiest, R.1    Gorszmann, R.J.2
  • 11
    • 0033450924 scopus 로고    scopus 로고
    • Biology of hepatic stellate cells and their possible in the pathogenesis of portal hypertension in cirrhosis
    • Pinzani M, Gentilini P. Biology of hepatic stellate cells and their possible in the pathogenesis of portal hypertension in cirrhosis. Semin Liver Dis 1999; 19: 397-410
    • (1999) Semin Liver Dis , vol.19 , pp. 397-410
    • Pinzani, M.1    Gentilini, P.2
  • 13
    • 0027416652 scopus 로고
    • Hyperdynamic state in chronic liver diseases
    • Groszmann RJ. Hyperdynamic state in chronic liver diseases. J Hepatol 1993; 17 Suppl. 2: S38-40
    • (1993) J Hepatol , vol.17 , Issue.SUPPL. 2
    • Groszmann, R.J.1
  • 14
    • 34547539830 scopus 로고    scopus 로고
    • Hepatic venous pressure gardient predicts clinical descompensation in patients with compensated cirrhosis
    • Ripoll C, Groszmann R, Garcia-Tsao G, et al. Hepatic venous pressure gardient predicts clinical descompensation in patients with compensated cirrhosis. Gastroenterology 2007; 133: 481-8
    • (2007) Gastroenterology , vol.133 , pp. 481-488
    • Ripoll, C.1    Groszmann, R.2    Garcia-Tsao, G.3
  • 15
    • 0025016059 scopus 로고
    • Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage
    • Groszmann RJ, Bosch J, Grace ND, et al. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology 1990; 99: 1401-7
    • (1990) Gastroenterology , vol.99 , pp. 1401-1407
    • Groszmann, R.J.1    Bosch, J.2    Grace, N.D.3
  • 16
    • 0028790232 scopus 로고
    • Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis
    • Feu F, García-Pagán JC, Bosch J, et al. Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet 1995; 346: 1056-9
    • (1995) Lancet , vol.346 , pp. 1056-1059
    • Feu, F.1    García-Pagán, J.C.2    Bosch, J.3
  • 17
    • 0034802621 scopus 로고    scopus 로고
    • Pharmacologic treatment of portal hypertension: Past, present and future
    • Boyer TD. Pharmacologic treatment of portal hypertension: past, present and future. Hepatology 2001; 34: 834-9
    • (2001) Hepatology , vol.34 , pp. 834-839
    • Boyer, T.D.1
  • 18
    • 0035109630 scopus 로고    scopus 로고
    • Current management of the complications of cirrhosis and portal hypertension: Variceal hemorrhage, ascites, and spontaneous bacterial peritonitis
    • Garcia-Tsao G. Current management of the complications of cirrhosis and portal hypertension: variceal hemorrhage, ascites, and spontaneous bacterial peritonitis. Gastroenterology 2001; 120: 726-48
    • (2001) Gastroenterology , vol.120 , pp. 726-748
    • Garcia-Tsao, G.1
  • 19
    • 0023778102 scopus 로고
    • Effects of vasopressin on the intravariceal pressure in patients with cirrhosis: Comparison with the effects on portal pressure
    • Bosch J, Bordas JM, Mastai R, et al. Effects of vasopressin on the intravariceal pressure in patients with cirrhosis: comparison with the effects on portal pressure. Hepatology 1988; 8: 861-5
    • (1988) Hepatology , vol.8 , pp. 861-865
    • Bosch, J.1    Bordas, J.M.2    Mastai, R.3
  • 20
    • 0030031571 scopus 로고    scopus 로고
    • Assessment of variceal pressure by continuous non-invasive endoscopic registration: A placebo controlled evaluation of the effect of terlipressin and octreotide
    • Nevens F, Van Steenbergen W, Yap SH, et al. Assessment of variceal pressure by continuous non-invasive endoscopic registration: a placebo controlled evaluation of the effect of terlipressin and octreotide. Gut 1996; 38: 129-34
    • (1996) Gut , vol.38 , pp. 129-134
    • Nevens, F.1    Van Steenbergen, W.2    Yap, S.H.3
  • 21
    • 0031058016 scopus 로고    scopus 로고
    • Time profile of the hemodynamic effects of terlipressin in portal hypertension
    • Escorsell A, Bandi JC, Moitinho E, et al. Time profile of the hemodynamic effects of terlipressin in portal hypertension. J Hepatol 1997; 26: 621-7
    • (1997) J Hepatol , vol.26 , pp. 621-627
    • Escorsell, A.1    Bandi, J.C.2    Moitinho, E.3
  • 22
    • 0036614743 scopus 로고    scopus 로고
    • Somatostatin and analogues in portal hypertension
    • Abraldes JG, Bosch J. Somatostatin and analogues in portal hypertension. Hepatology 2002; 35: 1305-12
    • (2002) Hepatology , vol.35 , pp. 1305-1312
    • Abraldes, J.G.1    Bosch, J.2
  • 23
    • 0035127182 scopus 로고    scopus 로고
    • Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats
    • Wiest R, Tsai MH, Groszmann RJ. Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats. Gastroenterology 2001; 120: 975-83
    • (2001) Gastroenterology , vol.120 , pp. 975-983
    • Wiest, R.1    Tsai, M.H.2    Groszmann, R.J.3
  • 24
    • 0029097260 scopus 로고
    • Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: A double-blind hemodynamic investigation
    • Cirera I, Feu F, Luca A, et al. Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: a double-blind hemodynamic investigation. Hepatology 1995; 22: 106-11
    • (1995) Hepatology , vol.22 , pp. 106-111
    • Cirera, I.1    Feu, F.2    Luca, A.3
  • 25
    • 0034962562 scopus 로고    scopus 로고
    • Somatostatin treatment and risk stratification by continuous portal pressure monitoring during acute variceal bleeding
    • Villanueva C, Ortiz J, Miñana J, et al. Somatostatin treatment and risk stratification by continuous portal pressure monitoring during acute variceal bleeding. Gastroenterology 2001; 121: 110-7
    • (2001) Gastroenterology , vol.121 , pp. 110-117
    • Villanueva, C.1    Ortiz, J.2    Miñana, J.3
  • 26
    • 16844366870 scopus 로고    scopus 로고
    • Hemodynamic effects of terlipressin and high somatostatin dose during acute variceal bleeding in nonreponders to the usual somatostatin dose
    • Villanueva C, Planella M, Aracil C, et al. Hemodynamic effects of terlipressin and high somatostatin dose during acute variceal bleeding in nonreponders to the usual somatostatin dose. Am J Gastroenterol 2005; 100: 624-30
    • (2005) Am J Gastroenterol , vol.100 , pp. 624-630
    • Villanueva, C.1    Planella, M.2    Aracil, C.3
  • 27
    • 0020449645 scopus 로고
    • Comparison of the effects of a cardioselective and a nonselective β-blocker on portal hypertension in patients with cirrhosis
    • Hillon P, Lebrec D, Muñoz C, et al. Comparison of the effects of a cardioselective and a nonselective β-blocker on portal hypertension in patients with cirrhosis. Hepatology 1982; 2: 528-31
    • (1982) Hepatology , vol.2 , pp. 528-531
    • Hillon, P.1    Lebrec, D.2    Muñoz, C.3
  • 28
    • 0021927396 scopus 로고
    • Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model
    • Kroeger RJ, Groszmann RJ. Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model. Hepatology 1985; 5: 97-101
    • (1985) Hepatology , vol.5 , pp. 97-101
    • Kroeger, R.J.1    Groszmann, R.J.2
  • 29
    • 0031003291 scopus 로고    scopus 로고
    • The portal pressure response to β-blockers is greater in cirrhotic patients without varices than in those with varices
    • Escorsell A, Ferayoni L, Bosch J, et al. The portal pressure response to β-blockers is greater in cirrhotic patients without varices than in those with varices. Gastroenterology 1997; 112: 2012-6
    • (1997) Gastroenterology , vol.112 , pp. 2012-2016
    • Escorsell, A.1    Ferayoni, L.2    Bosch, J.3
  • 30
    • 36549085173 scopus 로고    scopus 로고
    • How to prevent varices from bleeding: Shades of grey. The case for nonselective β-blockers
    • Thalheimer U, Bosch J, Burroughs AK. How to prevent varices from bleeding: shades of grey. The case for nonselective β-blockers. Gastroenterology 2007; 133: 2029-36
    • (2007) Gastroenterology , vol.133 , pp. 2029-2036
    • Thalheimer, U.1    Bosch, J.2    Burroughs, A.K.3
  • 31
    • 55049138157 scopus 로고    scopus 로고
    • Therapeutic tools in portal hypertension: Drugs
    • Groszmann RJ, Bosch J, editors, Dordrecht: Kluwer Academic Publishers
    • Albillos A. Therapeutic tools in portal hypertension: drugs. In: Groszmann RJ, Bosch J, editors. Portal hypertension in the 21st century. Dordrecht: Kluwer Academic Publishers, 2004: 175-84
    • (2004) Portal hypertension in the 21st century , pp. 175-184
    • Albillos, A.1
  • 32
    • 0030775671 scopus 로고    scopus 로고
    • Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: The good, the bad, the ugly
    • Groszmann RJ. Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: the good, the bad, the ugly. Gastroenterology 1997; 113: 1794-7
    • (1997) Gastroenterology , vol.113 , pp. 1794-1797
    • Groszmann, R.J.1
  • 33
    • 34548802928 scopus 로고    scopus 로고
    • Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis
    • Garcia-Tsao G, Sanyal A, Grace ND, et al. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology 2007; 46: 922-38
    • (2007) Hepatology , vol.46 , pp. 922-938
    • Garcia-Tsao, G.1    Sanyal, A.2    Grace, N.D.3
  • 34
    • 0020426024 scopus 로고
    • Nitroglycerin improves the hemodynamic response to vasopresin in portal hypertension
    • Groszmann RJ, Kravetz D, Bosch J, et al. Nitroglycerin improves the hemodynamic response to vasopresin in portal hypertension. Hepatology 1982; 2: 757-62
    • (1982) Hepatology , vol.2 , pp. 757-762
    • Groszmann, R.J.1    Kravetz, D.2    Bosch, J.3
  • 35
    • 0022632991 scopus 로고
    • Short-term effects of propranolol on portal pressure
    • Garcia-Tsao G, Grace ND, Groszmann RJ, et al. Short-term effects of propranolol on portal pressure. Hepatology 1986; 6: 101-6
    • (1986) Hepatology , vol.6 , pp. 101-106
    • Garcia-Tsao, G.1    Grace, N.D.2    Groszmann, R.J.3
  • 36
    • 0025906655 scopus 로고
    • Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. a randomized controlled study
    • Garcia-Pagán JC, Feu F, Bosch J, et al. Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. a randomized controlled study. Ann Intern Med 1991; 114: 869-73
    • (1991) Ann Intern Med , vol.114 , pp. 869-873
    • Garcia-Pagán, J.C.1    Feu, F.2    Bosch, J.3
  • 37
    • 17544385944 scopus 로고    scopus 로고
    • Propranolol plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension
    • Albillos A, García-Pagán JC, Iborra J, et al. Propranolol plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension. Gastroenterology 1998; 115: 116-23
    • (1998) Gastroenterology , vol.115 , pp. 116-123
    • Albillos, A.1    García-Pagán, J.C.2    Iborra, J.3
  • 38
    • 0027166092 scopus 로고
    • Propranolol compared with propranolol plus isosorbide dinitrate in portal-hypertensive patients: Long-term hemodynamic and renal effects
    • Vorobioff J, Picabea E, Gamen M, et al. Propranolol compared with propranolol plus isosorbide dinitrate in portal-hypertensive patients: long-term hemodynamic and renal effects. Hepatology 1993; 18: 477-84
    • (1993) Hepatology , vol.18 , pp. 477-484
    • Vorobioff, J.1    Picabea, E.2    Gamen, M.3
  • 39
    • 0037806032 scopus 로고    scopus 로고
    • Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: A double-blind RCT
    • García-Pagán JC, Morillas R, Bañares R, et al. Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: a double-blind RCT. Hepatology 2003; 37: 1260-6
    • (2003) Hepatology , vol.37 , pp. 1260-1266
    • García-Pagán, J.C.1    Morillas, R.2    Bañares, R.3
  • 40
    • 0027988534 scopus 로고
    • Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: Long-term hemodynamic and renal effects
    • Morillas R, Planas R, Cabré E, et al. Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: long-term hemodynamic and renal effects. Hepatology 1994; 20: 1502-8
    • (1994) Hepatology , vol.20 , pp. 1502-1508
    • Morillas, R.1    Planas, R.2    Cabré, E.3
  • 41
    • 0029092242 scopus 로고
    • Long-term effects of nadolol or nadolol plus isosorbide-5-mononitrate on renal function and ascites formation in patients with cirrhosis
    • Merkel C, Gatta A, Donada C, et al. Long-term effects of nadolol or nadolol plus isosorbide-5-mononitrate on renal function and ascites formation in patients with cirrhosis. Hepatology 1995; 22: 808-13
    • (1995) Hepatology , vol.22 , pp. 808-813
    • Merkel, C.1    Gatta, A.2    Donada, C.3
  • 42
    • 0030995729 scopus 로고    scopus 로고
    • Hemodynamic evaluation of the addition of isosorbide-5-mononitrate to nadolol in cirrhotic patients with insufficient response to the β-blocker alone
    • Merkel C, Sacerdoti D, Bolognesi M, et al. Hemodynamic evaluation of the addition of isosorbide-5-mononitrate to nadolol in cirrhotic patients with insufficient response to the β-blocker alone. Hepatology 1997; 26: 34-9
    • (1997) Hepatology , vol.26 , pp. 34-39
    • Merkel, C.1    Sacerdoti, D.2    Bolognesi, M.3
  • 43
    • 0033000308 scopus 로고    scopus 로고
    • Carvedilol a new beta-blocker with intrinsic anti-α1-adrenergic activity, has a greater portal hypotensiveb effect than propranolol in patients with cirrhosis
    • Bañares R, Moitinho E, Piqueras B, et al. Carvedilol a new beta-blocker with intrinsic anti-α1-adrenergic activity, has a greater portal hypotensiveb effect than propranolol in patients with cirrhosis. Hepatoloy 1999; 30: 79-83
    • (1999) Hepatoloy , vol.30 , pp. 79-83
    • Bañares, R.1    Moitinho, E.2    Piqueras, B.3
  • 44
    • 0033040460 scopus 로고    scopus 로고
    • Acute and chronic haemodynamic and renal effects of carvedilol in patients with cirrhosis
    • Stanley A, Therapondos G, Helmy A, et al. Acute and chronic haemodynamic and renal effects of carvedilol in patients with cirrhosis. J Hepatol 1999; 30: 479-84
    • (1999) J Hepatol , vol.30 , pp. 479-484
    • Stanley, A.1    Therapondos, G.2    Helmy, A.3
  • 45
    • 0036185720 scopus 로고    scopus 로고
    • Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension
    • Tripathi D, Therapondos G, Lui HF, et al. Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension. Aliment Pharmacol Ther 2002; 16: 373-80
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 373-380
    • Tripathi, D.1    Therapondos, G.2    Lui, H.F.3
  • 46
    • 0036894514 scopus 로고    scopus 로고
    • Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis
    • Bañares R, Moitinho E, Matilla A, et al. Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis. Hepatoloy 2002; 36: 1367-73
    • (2002) Hepatoloy , vol.36 , pp. 1367-1373
    • Bañares, R.1    Moitinho, E.2    Matilla, A.3
  • 47
    • 55049125956 scopus 로고    scopus 로고
    • Hemodynamic monitoring and rescue of nonresponders to first-line drug therapy with the combination of beta-blockers and prazosin or with ligation to prevent variceal rebleeding [abstract]
    • Aracil C, López-Balaguer JM, Perez-Rabasco E, et al. Hemodynamic monitoring and rescue of nonresponders to first-line drug therapy with the combination of beta-blockers and prazosin or with ligation to prevent variceal rebleeding [abstract]. Hepatology 2005; 42 Suppl. 1: 399
    • (2005) Hepatology , vol.42 , Issue.SUPPL. 1 , pp. 399
    • Aracil, C.1    López-Balaguer, J.M.2    Perez-Rabasco, E.3
  • 48
    • 33750705626 scopus 로고    scopus 로고
    • Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: A systematic review
    • D'Amico G, Garcia-Pagan JC, Luca A, et al. Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: a systematic review. Gastroenterology 2006; 131: 1611-24
    • (2006) Gastroenterology , vol.131 , pp. 1611-1624
    • D'Amico, G.1    Garcia-Pagan, J.C.2    Luca, A.3
  • 49
    • 0037382804 scopus 로고    scopus 로고
    • Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis
    • Abraldes JG, Tarantino I, Turnes J, et al. Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis. Hepatology 2003; 37: 902-8
    • (2003) Hepatology , vol.37 , pp. 902-908
    • Abraldes, J.G.1    Tarantino, I.2    Turnes, J.3
  • 50
    • 1942471049 scopus 로고    scopus 로고
    • Maintenance of hemodynamic response to treatment for portal hypertension and influence on complications of cirrhosis
    • Villanueva C, López-Balaguer JM, Aracil C, et al. Maintenance of hemodynamic response to treatment for portal hypertension and influence on complications of cirrhosis. J Hepatol 2004; 40: 757-65
    • (2004) J Hepatol , vol.40 , pp. 757-765
    • Villanueva, C.1    López-Balaguer, J.M.2    Aracil, C.3
  • 51
    • 0037443978 scopus 로고    scopus 로고
    • Revention of variceal rebleeding
    • Bosch J, García-Pagán JC. Revention of variceal rebleeding. Lancet 2003; 361: 952-4
    • (2003) Lancet , vol.361 , pp. 952-954
    • Bosch, J.1    García-Pagán, J.C.2
  • 52
    • 34249085757 scopus 로고    scopus 로고
    • Influence of spontaneous hemodynamic response on the efficacy of endoscopic therapy to prevent variceasl rebleeding [abstract]
    • Aracil C, Monfort D, Piqueras M, et al. Influence of spontaneous hemodynamic response on the efficacy of endoscopic therapy to prevent variceasl rebleeding [abstract]. J Hepatol 2005; 42 Suppl. 2: 76
    • (2005) J Hepatol , vol.42 , Issue.SUPPL. 2 , pp. 76
    • Aracil, C.1    Monfort, D.2    Piqueras, M.3
  • 53
    • 0030003919 scopus 로고    scopus 로고
    • Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding
    • Villanueva C, Balanzó J, Novella M, et al. Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding. N Engl J Med 1996; 334: 1624-9
    • (1996) N Engl J Med , vol.334 , pp. 1624-1629
    • Villanueva, C.1    Balanzó, J.2    Novella, M.3
  • 54
    • 1242269433 scopus 로고    scopus 로고
    • Targeting portal pressure measurements: A critical reappraisal
    • Thalheimer U, Mela M, Patch D, et al. Targeting portal pressure measurements: a critical reappraisal. Hepatology 2004; 39: 286-90
    • (2004) Hepatology , vol.39 , pp. 286-290
    • Thalheimer, U.1    Mela, M.2    Patch, D.3
  • 55
    • 35848938124 scopus 로고    scopus 로고
    • Acute hemodynamic response to beta-blockers for the prediction of long-term outcome in primary prophylaxis of variceal bleeding: Final results of a prospective study [abstract]
    • Aracil C, Colomo A, Ordas I, et al. Acute hemodynamic response to beta-blockers for the prediction of long-term outcome in primary prophylaxis of variceal bleeding: final results of a prospective study [abstract]. J Hepatol 2007; 46 Suppl. 1: S35
    • (2007) J Hepatol , vol.46 , Issue.SUPPL. 1
    • Aracil, C.1    Colomo, A.2    Ordas, I.3
  • 56
    • 40749107003 scopus 로고    scopus 로고
    • What to do with non-responders?
    • Groszmann RJ, Bosch J, editors, Dordrecht: Kluwer Academic Publishers
    • Villanueva C, Aracil C, Balanzó J. What to do with non-responders? In: Groszmann RJ, Bosch J, editors. Portal hypertension in the 21st century. Dordrecht: Kluwer Academic Publishers, 2004: 337-48
    • (2004) Portal hypertension in the 21st century , pp. 337-348
    • Villanueva, C.1    Aracil, C.2    Balanzó, J.3
  • 57
    • 0036896603 scopus 로고    scopus 로고
    • A la carte' treatment of portal hypertension: Adapting therapy to hemodynamic response for the prevention of bleeding
    • Bureau C
    • Bureau C, Péron JM, Alric L, et al. 'A la carte' treatment of portal hypertension: adapting therapy to hemodynamic response for the prevention of bleeding. Hepatology 2002; 36: 1361-6
    • (2002) Hepatology , vol.36 , pp. 1361-1366
    • Péron, J.M.1    Alric, L.2
  • 58
    • 33750618376 scopus 로고    scopus 로고
    • Hemodynamic response-guided therapy for prevention of variceal rebleeding: An uncontrolled pilot study
    • Gonzalez A, Agustin S, Perez M, et al. Hemodynamic response-guided therapy for prevention of variceal rebleeding: an uncontrolled pilot study. Hepatology 2006; 44: 806-12
    • (2006) Hepatology , vol.44 , pp. 806-812
    • Gonzalez, A.1    Agustin, S.2    Perez, M.3
  • 59
    • 1242314393 scopus 로고    scopus 로고
    • Changing clinical practice with measurements of portal pressure
    • Boyer TD. Changing clinical practice with measurements of portal pressure. Hepatology 2004; 39: 283-5
    • (2004) Hepatology , vol.39 , pp. 283-285
    • Boyer, T.D.1
  • 60
    • 1242291938 scopus 로고    scopus 로고
    • The hepatic venous pressure gradient: Anything worth doing should be done right
    • Groszmann RJ, Wongcharatrawee S. The hepatic venous pressure gradient: anything worth doing should be done right. Hepatology 2004; 39: 280-2
    • (2004) Hepatology , vol.39 , pp. 280-282
    • Groszmann, R.J.1    Wongcharatrawee, S.2
  • 61
    • 0035040713 scopus 로고    scopus 로고
    • Management of variceal hemorrhage in cirrhotic patients
    • Burroughs AK, Patch D. Management of variceal hemorrhage in cirrhotic patients. Gut 2001; 48: 738-40
    • (2001) Gut , vol.48 , pp. 738-740
    • Burroughs, A.K.1    Patch, D.2
  • 62
    • 20444415957 scopus 로고    scopus 로고
    • Evolving consensus in portal hypertension: Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension
    • De Franchis R. Evolving consensus in portal hypertension: report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2005; 43: 167-76
    • (2005) J Hepatol , vol.43 , pp. 167-176
    • De Franchis, R.1
  • 63
    • 0032993780 scopus 로고    scopus 로고
    • Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: A meta-analysis
    • Bernard B, Grange JD, Khac EN, et al. Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: a meta-analysis. Hepatology 1999; 29: 1655-61
    • (1999) Hepatology , vol.29 , pp. 1655-1661
    • Bernard, B.1    Grange, J.D.2    Khac, E.N.3
  • 64
    • 1542619692 scopus 로고    scopus 로고
    • Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: A randomized trial
    • Hou MC, Lin HC, Liu TT, et al. Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trial. Hepatology 2004; 39: 746-53
    • (2004) Hepatology , vol.39 , pp. 746-753
    • Hou, M.C.1    Lin, H.C.2    Liu, T.T.3
  • 65
    • 0026781087 scopus 로고
    • Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage
    • Soriano G, Guarner C, Tomás A, et al. Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage. Gastroenterology 1992; 103: 1267-72
    • (1992) Gastroenterology , vol.103 , pp. 1267-1272
    • Soriano, G.1    Guarner, C.2    Tomás, A.3
  • 66
    • 33749347803 scopus 로고    scopus 로고
    • Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage
    • Fernández J, Ruiz del Arbol L, Gómez C, et al. Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. Gastroenterology 2006; 131: 1049-56
    • (2006) Gastroenterology , vol.131 , pp. 1049-1056
    • Fernández, J.1    Ruiz del Arbol, L.2    Gómez, C.3
  • 67
    • 0029132797 scopus 로고
    • Early administration of terlipressin plus glyceryl trinatre to control active upper gastrointestinal bleeding in cirrhotic patients
    • Levacher S, Letoumelin P, Pateron D, et al. Early administration of terlipressin plus glyceryl trinatre to control active upper gastrointestinal bleeding in cirrhotic patients. Lancet 1995; 346: 865-8
    • (1995) Lancet , vol.346 , pp. 865-868
    • Levacher, S.1    Letoumelin, P.2    Pateron, D.3
  • 68
    • 0035804295 scopus 로고    scopus 로고
    • Early administration of vapreotide for variceal bleeding in patients with cirrhosis
    • Calés P, Masliah C, Bernard B, et al. Early administration of vapreotide for variceal bleeding in patients with cirrhosis. N Engl J Med 2001; 334: 23-8
    • (2001) N Engl J Med , vol.334 , pp. 23-28
    • Calés, P.1    Masliah, C.2    Bernard, B.3
  • 69
    • 0029847149 scopus 로고    scopus 로고
    • Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage
    • Feu F, Ruiz del Arbol L, Bañares R, et al. Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage. Gastroenterology 1996; 111: 1291-9
    • (1996) Gastroenterology , vol.111 , pp. 1291-1299
    • Feu, F.1    Ruiz del Arbol, L.2    Bañares, R.3
  • 70
    • 0035123250 scopus 로고    scopus 로고
    • Octreotide for acute esophageal variceal bleeding: A meta-analysis
    • Corley DA, Cello JP, Adkinsson W, et al. Octreotide for acute esophageal variceal bleeding: a meta-analysis. Gastroenterology 2001; 120: 946-54
    • (2001) Gastroenterology , vol.120 , pp. 946-954
    • Corley, D.A.1    Cello, J.P.2    Adkinsson, W.3
  • 71
    • 0038297513 scopus 로고    scopus 로고
    • Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: A Cochrane meta-analysis
    • D'Amico G, Pietrosi G, Tarantino I, et al. Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: a Cochrane meta-analysis. Gastroenterology 2003; 124: 1277-91
    • (2003) Gastroenterology , vol.124 , pp. 1277-1291
    • D'Amico, G.1    Pietrosi, G.2    Tarantino, I.3
  • 72
    • 0032769961 scopus 로고    scopus 로고
    • Somatostatin alone or combined with emergency sclerotherapy in the treatment of acute esophageal variceal bleeding: A prospective randomized trial
    • Villanueva C, Ortiz J, Sàbat M, et al. Somatostatin alone or combined with emergency sclerotherapy in the treatment of acute esophageal variceal bleeding: a prospective randomized trial. Hepatology 1999; 30: 384-9
    • (1999) Hepatology , vol.30 , pp. 384-389
    • Villanueva, C.1    Ortiz, J.2    Sàbat, M.3
  • 73
    • 0033403439 scopus 로고    scopus 로고
    • Endoscopic treatments for portal hypertension
    • De Franchis R, Primignani M. Endoscopic treatments for portal hypertension. Semin Liver Dis 1999; 19: 439-55
    • (1999) Semin Liver Dis , vol.19 , pp. 439-455
    • De Franchis, R.1    Primignani, M.2
  • 74
    • 0029089566 scopus 로고
    • Endoscopic ligation compared with sclerothepary for treatment of esophageal variceal bleeding: A meta-analysis
    • Laine L, Cook D. Endoscopic ligation compared with sclerothepary for treatment of esophageal variceal bleeding: a meta-analysis. Ann Intern Med 1995; 123: 280-7
    • (1995) Ann Intern Med , vol.123 , pp. 280-287
    • Laine, L.1    Cook, D.2
  • 75
    • 0030904803 scopus 로고    scopus 로고
    • Emergency banding ligation versus sclerotherapy for the control of active bleeding from esophageal varices
    • Lo GH, Lai KH, Cheng JS, et al. Emergency banding ligation versus sclerotherapy for the control of active bleeding from esophageal varices. Hepatology 1997; 25: 1101-4
    • (1997) Hepatology , vol.25 , pp. 1101-1104
    • Lo, G.H.1    Lai, K.H.2    Cheng, J.S.3
  • 76
    • 33748097739 scopus 로고
    • Emergency sclerotherapy vs rubber band ligation for actively bleeding esophageal varices in a randomized prospective study [abstract]
    • Jensen DM, Kovacs TOG, Randall G, et al. Emergency sclerotherapy vs rubber band ligation for actively bleeding esophageal varices in a randomized prospective study [abstract]. Gastrointest Endosc 1994; 40: 241
    • (1994) Gastrointest Endosc , vol.40 , pp. 241
    • Jensen, D.M.1    Kovacs, T.O.G.2    Randall, G.3
  • 77
    • 33748100221 scopus 로고    scopus 로고
    • A randomized controlled trial comparing ligation and sclerotherapy as emergency endioscopic treatment added to somatostatin in acute variceal bleeding
    • Villanueva C, Piqueras M, Aracil C, et al. A randomized controlled trial comparing ligation and sclerotherapy as emergency endioscopic treatment added to somatostatin in acute variceal bleeding. J Hepatol 2006; 45: 560-7
    • (2006) J Hepatol , vol.45 , pp. 560-567
    • Villanueva, C.1    Piqueras, M.2    Aracil, C.3
  • 78
    • 0036192233 scopus 로고    scopus 로고
    • Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: A meta-analysis
    • Bañares R, Albillos A, Rincón D, et al. Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis. Hepatology 2002; 35: 609-15
    • (2002) Hepatology , vol.35 , pp. 609-615
    • Bañares, R.1    Albillos, A.2    Rincón, D.3
  • 79
    • 0342545883 scopus 로고    scopus 로고
    • Transjugular intrahepatic portosystemic shunt
    • Burroughs AK, Patch D. Transjugular intrahepatic portosystemic shunt. Semin Liver Dis 1999; 19: 457-73
    • (1999) Semin Liver Dis , vol.19 , pp. 457-473
    • Burroughs, A.K.1    Patch, D.2
  • 80
    • 0035743114 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial comparing different schedules of somatostatin in the treatment of acute variceal bleeding
    • Moitinho E, Planas R, Bañares R, et al. Multicenter randomized controlled trial comparing different schedules of somatostatin in the treatment of acute variceal bleeding. J Hepatol 2001; 35: 712-8
    • (2001) J Hepatol , vol.35 , pp. 712-718
    • Moitinho, E.1    Planas, R.2    Bañares, R.3
  • 81
    • 4644298640 scopus 로고    scopus 로고
    • Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding
    • Monescillo A, Martínez-Lagares F, Ruiz-del-Arbol L, et al. Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding. Hepatology 2004; 40: 793-801
    • (2004) Hepatology , vol.40 , pp. 793-801
    • Monescillo, A.1    Martínez-Lagares, F.2    Ruiz-del-Arbol, L.3
  • 82
    • 5144222624 scopus 로고    scopus 로고
    • Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: A randomized, double-blind trial
    • Bosch J, Thabut D, Bendtsen F, et al. Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial. Gastroenterology 2004; 127: 1123-30
    • (2004) Gastroenterology , vol.127 , pp. 1123-1130
    • Bosch, J.1    Thabut, D.2    Bendtsen, F.3
  • 83
    • 14644414260 scopus 로고    scopus 로고
    • Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: A meta-analysis
    • Karsan HA, Morton SC, Shekelle PG, et al. Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysis. Dig Dis Sci 2005; 50: 399-406
    • (2005) Dig Dis Sci , vol.50 , pp. 399-406
    • Karsan, H.A.1    Morton, S.C.2    Shekelle, P.G.3
  • 84
    • 0034074123 scopus 로고    scopus 로고
    • Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding
    • Gournay J, Masliah C, Martin T, et al. Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding. Hepatology 2000; 31: 1239-45
    • (2000) Hepatology , vol.31 , pp. 1239-1245
    • Gournay, J.1    Masliah, C.2    Martin, T.3
  • 85
    • 0035975395 scopus 로고    scopus 로고
    • Endoscopic ligation compared with combined treatment with nadolol plus isosorbide mononitrate to prevent recurrent variceal bleeding
    • Villanueva C, Miñana J, Ortiz J, et al. Endoscopic ligation compared with combined treatment with nadolol plus isosorbide mononitrate to prevent recurrent variceal bleeding. N Engl J Med 2001; 345: 647-55
    • (2001) N Engl J Med , vol.345 , pp. 647-655
    • Villanueva, C.1    Miñana, J.2    Ortiz, J.3
  • 86
    • 0036788252 scopus 로고    scopus 로고
    • A randomized controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis
    • Patch D, Sabin CA, Goulis J, et al. A randomized controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis. Gastroenterology 2002; 123: 1013-9
    • (2002) Gastroenterology , vol.123 , pp. 1013-1019
    • Patch, D.1    Sabin, C.A.2    Goulis, J.3
  • 87
    • 0036731118 scopus 로고    scopus 로고
    • Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal bleeding
    • Lo GH, Chen WC, Chen MH, et al. Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal bleeding. Gastroenterology 2002; 123: 728-34
    • (2002) Gastroenterology , vol.123 , pp. 728-734
    • Lo, G.H.1    Chen, W.C.2    Chen, M.H.3
  • 88
    • 4243249032 scopus 로고    scopus 로고
    • Band ligation versus medical therapy in prevention of variceal rebleeding: A randomized controlled study in schistosomal hepatic fibrosis and HCV coinfection [abstract]
    • El-Tahawy M, Mahmoud S, Waked I, et al. Band ligation versus medical therapy in prevention of variceal rebleeding: a randomized controlled study in schistosomal hepatic fibrosis and HCV coinfection [abstract]. Gastroenterology 2003; 124: A663-4
    • (2003) Gastroenterology , vol.124
    • El-Tahawy, M.1    Mahmoud, S.2    Waked, I.3
  • 89
    • 22844447751 scopus 로고    scopus 로고
    • Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: Comparison of cirrhotic and noncirrhotic patients
    • Aug;
    • Sarin SK, Wadhawan M, Gupta R, et al. Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: comparison of cirrhotic and noncirrhotic patients. Dig Dis Sci 2005 Aug; 50 (8): 1538-47
    • (2005) Dig Dis Sci , vol.50 , Issue.8 , pp. 1538-1547
    • Sarin, S.K.1    Wadhawan, M.2    Gupta, R.3
  • 90
    • 33746448355 scopus 로고    scopus 로고
    • Comparative study between nadolol and 5-isosorbide mononitrate vs endoscopic band ligation plus sclerotherapy in the prevention of variceal rebleeding in cirrhotic patients: A randomized controlled trial
    • Aug 15;
    • Romero G, Kravetz D, Argonz J, et al. Comparative study between nadolol and 5-isosorbide mononitrate vs endoscopic band ligation plus sclerotherapy in the prevention of variceal rebleeding in cirrhotic patients: a randomized controlled trial. Aliment Pharmacol Ther 2006 Aug 15; 24 (4): 601-11
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.4 , pp. 601-611
    • Romero, G.1    Kravetz, D.2    Argonz, J.3
  • 91
    • 0033843585 scopus 로고    scopus 로고
    • Endoscopic variceal ligation plus nadolol and sucralfate compared with ligation alone for the prevention of variceal rebleeding: A prospective, randomized trial
    • Lo GH, Lai KH, Cheng JS, et al. Endoscopic variceal ligation plus nadolol and sucralfate compared with ligation alone for the prevention of variceal rebleeding: a prospective, randomized trial. Hepatology 2000; 32: 461-565
    • (2000) Hepatology , vol.32 , pp. 461-565
    • Lo, G.H.1    Lai, K.H.2    Cheng, J.S.3
  • 92
    • 14244252176 scopus 로고    scopus 로고
    • Variceal ligation plus nadolol compared with ligation for prophylaxis of variceal rebleeding: A multicenter trial
    • De la Peña J, Brullet E, Sanchez-Hernández E, et al. Variceal ligation plus nadolol compared with ligation for prophylaxis of variceal rebleeding: a multicenter trial. Hepatology 2005; 41: 572-8
    • (2005) Hepatology , vol.41 , pp. 572-578
    • De la Peña, J.1    Brullet, E.2    Sanchez-Hernández, E.3
  • 93
    • 47549119070 scopus 로고    scopus 로고
    • Meta-analysis: Combining endoscopic and drug therapy to prevent variceal rebleeding in cirrhosis
    • Gonzalez R, Zamora J, Gomez-Camarero J, et al. Meta-analysis: combining endoscopic and drug therapy to prevent variceal rebleeding in cirrhosis. Ann Intern Med 2008; 149: 109-22
    • (2008) Ann Intern Med , vol.149 , pp. 109-122
    • Gonzalez, R.1    Zamora, J.2    Gomez-Camarero, J.3
  • 94
    • 33846282461 scopus 로고    scopus 로고
    • Nadolol + isosorbide-5-mononitrate (NAD + ISMN) vs NAD + ISMN + endoscopic band ligation in the prevention of rebleeding in patients with cirrhosis: Preliminary results of a multicenter RCT [abstract]
    • García-Pagán JC, Villanueva C, Albillos A, et al. Nadolol + isosorbide-5-mononitrate (NAD + ISMN) vs NAD + ISMN + endoscopic band ligation in the prevention of rebleeding in patients with cirrhosis: preliminary results of a multicenter RCT [abstract]. J Hepatol 2006; 44 Suppl. 2: S11-2
    • (2006) J Hepatol , vol.44 , Issue.SUPPL. 2
    • García-Pagán, J.C.1    Villanueva, C.2    Albillos, A.3
  • 95
    • 47549115159 scopus 로고    scopus 로고
    • Endoscopic variceal ligation (EVL) plus propranolol (P) and isosorbide mononitrate (ISMN) versus EVL alone in secondary prophylaxis of variceal bleeding: A prospective RCT [abstract]
    • Jha SK, Kumar A, Sharma BC, et al. Endoscopic variceal ligation (EVL) plus propranolol (P) and isosorbide mononitrate (ISMN) versus EVL alone in secondary prophylaxis of variceal bleeding: a prospective RCT [abstract]. Hepatology 2007; 46 Suppl. 1: 250-1A
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Jha, S.K.1    Kumar, A.2    Sharma, B.C.3
  • 96
    • 0032858182 scopus 로고    scopus 로고
    • Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: A meta-analysis
    • Papatheodoridis GV, Goulis J, Leandro G, et al. Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: a meta-analysis. Hepatology 1999; 30: 612-22
    • (1999) Hepatology , vol.30 , pp. 612-622
    • Papatheodoridis, G.V.1    Goulis, J.2    Leandro, G.3
  • 97
    • 18244380855 scopus 로고    scopus 로고
    • TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: A randomized controlled trial
    • Escorsell A, Bañares R, García-Pagán JC, et al. TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial. Hepatology 2002; 35: 385-92
    • (2002) Hepatology , vol.35 , pp. 385-392
    • Escorsell, A.1    Bañares, R.2    García-Pagán, J.C.3
  • 98
    • 33646370199 scopus 로고    scopus 로고
    • Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: A randomized trial
    • Henderson JM, Boyer TD, Kutner MH, et al. Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial. Gastroenterology 2006; 130: 1643-51
    • (2006) Gastroenterology , vol.130 , pp. 1643-1651
    • Henderson, J.M.1    Boyer, T.D.2    Kutner, M.H.3
  • 99
    • 0018859516 scopus 로고
    • Propranolol: A medical treatment for portal hypertension?
    • Lebrec D, Nouel O, Corbic M, et al. Propranolol: a medical treatment for portal hypertension? Lancet 1980; II: 180-2
    • (1980) Lancet , vol.2 , pp. 180-182
    • Lebrec, D.1    Nouel, O.2    Corbic, M.3
  • 100
    • 0025810312 scopus 로고
    • Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices: An anlysis of data and prognostic factors in 589 patients from four randomized clinical trials
    • Poynard T, Calès P, Pasta L, et al. Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices: an anlysis of data and prognostic factors in 589 patients from four randomized clinical trials. N Engl J Med 1991; 324: 1532-8
    • (1991) N Engl J Med , vol.324 , pp. 1532-1538
    • Poynard, T.1    Calès, P.2    Pasta, L.3
  • 101
    • 0035083039 scopus 로고    scopus 로고
    • A meta-analysis of endoscopic variceal ligation for primary prophylaxis of esophageal variceal bleeding
    • Imperiale TF, Chalasani N. A meta-analysis of endoscopic variceal ligation for primary prophylaxis of esophageal variceal bleeding. Hepatology 2001; 33: 802-7
    • (2001) Hepatology , vol.33 , pp. 802-807
    • Imperiale, T.F.1    Chalasani, N.2
  • 102
    • 14644399798 scopus 로고    scopus 로고
    • Meta-analysis: Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding
    • Khuroo MS, Khuroo NS, Farahat KL, et al. Meta-analysis: endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding. Aliment Pharmacol Ther 2005; 21: 347-61
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 347-361
    • Khuroo, M.S.1    Khuroo, N.S.2    Farahat, K.L.3
  • 103
    • 35848933212 scopus 로고    scopus 로고
    • Preventing first variceal hemorrhage in cirrhosis
    • Albillos A. Preventing first variceal hemorrhage in cirrhosis. J Clin Gastroenterol 2007; 41: S305-11
    • (2007) J Clin Gastroenterol , vol.41
    • Albillos, A.1
  • 104
    • 17144419769 scopus 로고    scopus 로고
    • Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding
    • Sarin SK, Wadhawan M, Agarwal SR, et al. Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding. Am J Gastroenterol 2005; 100: 797-804
    • (2005) Am J Gastroenterol , vol.100 , pp. 797-804
    • Sarin, S.K.1    Wadhawan, M.2    Agarwal, S.R.3
  • 105
    • 40849132182 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed [abstract]
    • Tripathi D, Ferguson JW, Kochar N, et al. Multicenter randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed [abstract]. Hepatology 2007; 46 Suppl. 1: 269A
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Tripathi, D.1    Ferguson, J.W.2    Kochar, N.3
  • 106
    • 0034792003 scopus 로고    scopus 로고
    • Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive β-blockers
    • García-Pagán JC, Villanueva C, Vila MC, et al. Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive β-blockers. Gastroenterology 2001; 121: 908-14
    • (2001) Gastroenterology , vol.121 , pp. 908-914
    • García-Pagán, J.C.1    Villanueva, C.2    Vila, M.C.3
  • 107
    • 33644783067 scopus 로고    scopus 로고
    • Pharmacological reduction of portal pressure and long-term risk of first variceal bleeding in patients with cirrhosis
    • Turnes J, Garcia-Pagan JC, Abraldes JG, et al. Pharmacological reduction of portal pressure and long-term risk of first variceal bleeding in patients with cirrhosis. Am J Gastroenterol 2006; 101: 506-12
    • (2006) Am J Gastroenterol , vol.101 , pp. 506-512
    • Turnes, J.1    Garcia-Pagan, J.C.2    Abraldes, J.G.3
  • 108
    • 4143109070 scopus 로고    scopus 로고
    • A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis
    • Merkel C, Marin R, Angeli P, et al. A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis. Gastroenterology 2004; 127: 476-84
    • (2004) Gastroenterology , vol.127 , pp. 476-484
    • Merkel, C.1    Marin, R.2    Angeli, P.3
  • 109
    • 0030781407 scopus 로고    scopus 로고
    • Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis
    • Angelico M, Carli L, Piat C, et al. Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis. Gastroenterology 1997; 113: 1632-9
    • (1997) Gastroenterology , vol.113 , pp. 1632-1639
    • Angelico, M.1    Carli, L.2    Piat, C.3
  • 110
    • 0037308188 scopus 로고    scopus 로고
    • Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: A preliminary study
    • Abecasis R, Kravetz D, Fassio E, et al. Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: a preliminary study. Hepatology 2003; 37: 359-65
    • (2003) Hepatology , vol.37 , pp. 359-365
    • Abecasis, R.1    Kravetz, D.2    Fassio, E.3
  • 111
    • 40749105720 scopus 로고    scopus 로고
    • Gastric varices
    • Groszmann RJ, Bosch J, editors, Dordrecht: Kluwer Academic Publishers
    • Sarin SK. Gastric varices. In: Groszmann RJ, Bosch J, editors. Portal hypertension in the 21st century. Dordrecht: Kluwer Academic Publishers, 2004: 277-300
    • (2004) Portal hypertension in the 21st century , pp. 277-300
    • Sarin, S.K.1
  • 112
    • 0035035401 scopus 로고    scopus 로고
    • A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices
    • Lo GH, Lai KH, Cheng JS, et al. A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices. Hepatology 2001; 33: 1060-4
    • (2001) Hepatology , vol.33 , pp. 1060-1064
    • Lo, G.H.1    Lai, K.H.2    Cheng, J.S.3
  • 114
    • 0034234775 scopus 로고    scopus 로고
    • Natural history of portal hypertensive gastropathy in patients with liver cirrhosis
    • Primignani M, Carpinelli L, Preatoni P, et al. Natural history of portal hypertensive gastropathy in patients with liver cirrhosis. Gastroenterology 2000; 119: 181-7
    • (2000) Gastroenterology , vol.119 , pp. 181-187
    • Primignani, M.1    Carpinelli, L.2    Preatoni, P.3
  • 115
    • 0028795315 scopus 로고
    • Severe portal hypertensive gastropathy and antral vascular ectasia are distinct entities in patients with cirrhosis
    • Payen JL, Cales P, Voigt JJ, et al. Severe portal hypertensive gastropathy and antral vascular ectasia are distinct entities in patients with cirrhosis. Gastroenterology 1995; 108: 138-44
    • (1995) Gastroenterology , vol.108 , pp. 138-144
    • Payen, J.L.1    Cales, P.2    Voigt, J.J.3
  • 116
    • 0025811617 scopus 로고
    • Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis
    • Perez-Ayuso RM, Pique JM, Bosch J, et al. Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis. Lancet 1991; 337: 1431-4
    • (1991) Lancet , vol.337 , pp. 1431-1434
    • Perez-Ayuso, R.M.1    Pique, J.M.2    Bosch, J.3
  • 117
    • 0028288360 scopus 로고
    • Endoscopic laser treatment of diffuse gastric antral vascular ectasia
    • Potamiano S, Carter CR, Anderson JR. Endoscopic laser treatment of diffuse gastric antral vascular ectasia. Gut 1994; 35: 461-3
    • (1994) Gut , vol.35 , pp. 461-463
    • Potamiano, S.1    Carter, C.R.2    Anderson, J.R.3
  • 118
    • 55049106850 scopus 로고    scopus 로고
    • Endoscopic treatment with argon plasma coagulation for portal hypertensive gastropathy with no response to pharmacological therapy [abstract]
    • González-Suárez B, Monfort D, Piqueras M, et al. Endoscopic treatment with argon plasma coagulation for portal hypertensive gastropathy with no response to pharmacological therapy [abstract]. J Hepatol 2003; 38 (185A): 59
    • (2003) J Hepatol , vol.38 , Issue.185 A , pp. 59
    • González-Suárez, B.1    Monfort, D.2    Piqueras, M.3
  • 119
    • 29544444703 scopus 로고    scopus 로고
    • Approaches to the management of pediatric portal hypertension: Results of an informal survey
    • Groszmann RJ, Bosch J, editors, Dordrecht: Kluwer Academic Publishers
    • Shneider BL. Approaches to the management of pediatric portal hypertension: results of an informal survey. In: Groszmann RJ, Bosch J, editors. Portal hypertension in the 21st century. Dordrecht: Kluwer Academic Publishers, 2004: 167-72
    • (2004) Portal hypertension in the 21st century , pp. 167-172
    • Shneider, B.L.1
  • 120
    • 0034877694 scopus 로고    scopus 로고
    • Drug treatment of the complications of cirrhosis in the older adult
    • Anand BS. Drug treatment of the complications of cirrhosis in the older adult. Drugs Aging 2001; 18: 575-85
    • (2001) Drugs Aging , vol.18 , pp. 575-585
    • Anand, B.S.1
  • 121
    • 0036773958 scopus 로고    scopus 로고
    • Use of cardiovascular medications in the elderly
    • Ali Raza J, Movahed A. Use of cardiovascular medications in the elderly. Int J Cardiol 2002; 85: 203-15
    • (2002) Int J Cardiol , vol.85 , pp. 203-215
    • Ali Raza, J.1    Movahed, A.2


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