Session 6: Prevention of Rebleeding

Portal Hypertension IV: Proceedings of the 4th Baveno International Consensus Workshop

Volumn , Issue , 2007, Pages 262-282

  Bernard Chabert, Brigitte ^a   Sauerbruch, Tilman ^b   Lo, Gin Ho ^c,d   Sanyal, Arun J ^e   Henderson, J Michael ^f   Shiha, Gamal ^g   Lin, Han Chieh ^d,h   Villanueva, Càndid ⁱ   Vinel, Jean Pierre ^j   Lebrec, Didier ^k,l  

^a Centre Hôpitalier Universitaire Robert Debré   (France)

^b UNIVERSITY OF BONN   (Germany)

^c KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^f LERNER RESEARCH INSTITUTE   (United States)

^g MANSOURA UNIVERSITY HOSPITAL   (Egypt)

^h TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

ⁱ HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^j CHU PURPAN   (France)

^k INSERM   (France)

^l BEAUJON HOSPITAL   (France)

more..

Author keywords

Clinical randomised trials; Isosorbide mononitrate; Oesophageal varices; Sclerotherapy; blockers

Indexed keywords

EID: 84986575934     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470988831.ch11     Document Type: Chapter

References (105)

1. Bernard B, Lebrec D, Mathurin P et al. Beta-adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis. A meta-analysis. Hepatology. 1997;25: 63-70.
2. Lebrec D, Poynard T, Hillon P et al. Propranolol for prevention or recurrent gastrointestinal bleeding in patients with cirrhosis. N Engl J Med. 1981;305:1371-1374.
3. Burroughs AK, Jenkins WJ, Sherlock S et al. Controlled trial of propranolol for the prevention of recurrent variceal hemorrhage in patients with cirrhosis. N Engl J Med. 1983;25: 1539-1542.
4. Villeneuve JP, Pomier-Layrargues G, Infante-Rivard C et al. Propranolol for the prevention of recurrent variceal hemorrhage: a controlled trial. Hepatology. 1986;6: 1239-1243.
5. Colombo M, De Franchis R, TommasiniMet al. ß-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis:a multicenter randomised controlled trial. Hepatology. 1989;9: 433-438.
6. Colman J, Jones P, Finch C et al. Propranolol in the prevention of variceal haemorrhage in alcoholic cirrhotic patients (abstract). Hepatology. 1990;12: 851.
7. Garden OJ, Mills PR, Birnie GG et al. Propranolol in the prevention of recurrent variceal hemorrhage in cirrhotic patients. Gastroenterology. 1990;98: 185-190.
8. Rossi V, Calès P, Burtin P et al. Prevention of recurrent variceal bleeding in alcoholic cirrhotic patients: prospective controlled trial of propranolol and sclerotherapy. J Hepatol. 1991;12: 283-289.
9. D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a metaanalytic review. Hepatology. 1995;22: 332-353.
10. Bernard B, Lebrec D, Mathurin P et al. Propranolol and sclerotherapy in the prevention of gastrointestinal rebleeding in patients with cirrhosis. A meta-analysis. J Hepatol. 1997;26: 312-324.
11. Gournay J, Masliah C, Martin T et al. Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding. Hepatology. 2000;31: 1239-1245.
12. Patti R, D'Amico G, Pasta L et al. Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double-blind placebo-controlled randomised trial (abstract). J Hepatol. 1999;30(suppl1): 81.
13. Zhang Qyuan R, Wang H. The randomised controlled trial of isosorbide mononitrate plus propranolol compared with propranolol alone for the prevention of variceal rebleeding. Zhonghua Yi Xue Za Zhi. 2002;8217: 1157-1159.
14. Villanueva C, Minana J, Ortiz J et al. Endoscopic ligation compared with combined treatment with nadolol plus isosorbide mononitrate to prevent recurrent variceal bleeding. N Eng J Med. 2001;345: 647-655.
15. Lo GH, Chen WC, Hsu PI et al. Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal bleeding. Gastroenterology. 2002;123: 728-734.
16. Patch D, Sabin CA, Goulis J et al. A randomised, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis. Gastroenterology. 2002;123: 1013-1019.
17. De Franchis R, Primignani M. Endoscopic treatments for portal hypertension. Semin Liver Dis. 1999;19: 439-455.
18. Sauerbruch T, Scheurlen C, Neubrand M. Endoscopic treatment of variceal bleeding. In: Tytgat GNJ, Classen M, Waye DJ, Nakazawa S (eds). Practice of therapeutic endoscopy. 2nd edn, London, Edinburgh, New York, WB Saunders, 2000; 13-29.
19. Sauerbruch T, Weinzierl M, Ansari H et al. Injection sclerotherapy of oesophageal variceal haemorrhage. A prospective long-term follow-up study. Endoscopy. 1987;19: 181-184.
20. Stiegmann GV, Goff JS, Michaletz-Onody PA et al. Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices. N Engl J Med. 1992;326: 1527-1532.
21. Stiegmann GV, Sun JH, Hammond WS. Results of experimental endoscopic esophageal varix ligation. Am Surg. 1988;54: 105-108.
22. Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. Ann Intern Med. 1995;123: 280-287.
23. Goulis J, Burroughs A. Portal hypertensive bleeding. In: McDonald JWD, Burroughs A, Feagan BG (eds). Evidence-based gastroenterology and hepatology. London, Blackwell, 2004.
24. Zargar SA, Javid G, Khan BA et al. Endoscopic ligation vs. sclerotherapy in adults with extrahepatic portal venous obstruction: a prospective randomised study. GastroIntEIS Endosc. 2005;61: 58-66.
25. Karsan HA, Morton SC, Shekelle PG et al. Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysis. Dig Dis Sci. 2005;50: 399-406.
26. Lo GH, Lai KH, Cheng JS et al. The additive effect of sclerotherapy to patients receiving repeated endoscopic variceal ligation: a prospective, randomised trial. Hepatology. 1998;28: 391-395.
27. Lebrec D, Poynard T, Bernuau J et al. A randomised controlled study of propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a final report. Hepatology. 1984; 4:355-358.
28. Lo GH, Lai KH, Cheng JS et al. The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial. GastrointEIS Endosc. 2001;53: 579-584.
29. Lo GH, Liang HL, Lai KH et al. The impact of endoscopic variceal ligation on the pressure of the portal venous system. J Hepatol. 1996;24: 74-80.
30. Lo GH, Lai KH, Cheng JS et al. Endoscopic variceal ligation plus nadolol and sucralfate compared with ligation alone for the prevention of variceal rebleeding:a prospective, randomised trial. Hepatology. 2000;32: 461-465.
31. de La Pena J, Sanchez-Hernandez E, Rivero M et al. Variceal ligation plus nadolol compared with ligation for prophylaxis of variceal rebleeding: a multicenter trial. Hepatology. 2005;41: 572-578.
32. Cabrera J, Maynar M, Granados R et al. Transjugular intrahepatic portosystemic shunt versus sclerotherapy in the elective treatment of variceal hemorrhage. Gastroenterology. 1996;110: 832-839.
33. Sanyal AJ, Freedman AM, Luketic VA et al. Transjugular intrahepatic portosystemic shunts compared with endoscopic sclerotherapy for the prevention of recurrent variceal hemorrhage. A randomised, controlled trial. Ann Intern Med. 1997;126: 849-857.
34. Cello JP, Ring EJ, Olcott EW et al. Endoscopic sclerotherapy compared with percutaneous transjugular intrahepatic portosystemic shunt after initial sclerotherapy in patients with acute variceal hemorrhage. A randomised, controlled trial. Ann Intern Med. 1997;126: 858-865.
35. Merli M, Salerno F, Riggio O et al. Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal bleeding in cirrhosis: a randomised multicenter trial. Hepatology. 1998;27: 48-53.
36. Garcia-Villarreal L, Martinez-Lagares F, Sierra A et al. Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal rebleeding after recent variceal hemorrhage. Hepatology. 1999;29:27-32.
37. Rössle M, Deibert P, Haag K et al. Randomised trial of transjugularintrahepatic- portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding. Lancet. 1997;349: 1043-1049.
38. Sauer P, Theilmann L, Stremmel W et al. Transjugular intrahepatic portosystemic stent shunt versus sclerotherapy plus propranolol for variceal rebleeding. Gastroenterology. 1997;11: 1623-1631.
39. Groupe d'Etude des Anastomoses Intra-Hépatiques. TIPS vs. sclerotherapy + propranolol in the prevention of variceal rebleeding: preliminary results of a multicenter randomised trial. (abstract) Hepatology. 1995;22: 297A.
40. Jalan R, Forreis EH, Stanley AJ et al. A randomised trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices. Hepatology. 1997;26:1115-1122.
41. Sauer P, Hansmann J, Richter GM et al. Endoscopic variceal ligation plus propranolol vs. transjugular intrahepatic portosystemic stent shunt: a long-term randomised trial. Endoscopy. 2002;34: 690-697.
42. Pomier-Layrargues G, Villeneuve JP, Deschenes M et al. Transjugular intrahepatic portosystemic shunt (TIPS) versus endoscopic variceal ligation in the prevention of variceal rebleeding in patients with cirrhosis: a randomised trial. Gut. 2001;48: 390-396.
43. Lin OS, Wu SS, Chen YY et al. Bacterial peritonitis after elective endoscopic variceal ligation: a prospective study. Am J Gastroenterol. 2000;95:214-217.
44. Rosemurgy AS, Serafini FM, Zweibel BR et al. Transjugular intrahepatic portosystemeic shunt vs. small-diameter prosthetic H-graft portacaval shunt:extended follow-up of an expanded randomised prospective trial. J Gastrointestinal Surgery. 2000;4: 589-597.
45. Henderson JM, Boyer TD, Kutner MH et al. and the DIVERT study group. DSRS vs. TIPS for refractory variceal bleeding: a prospective randomised controlled trial. Hepatology. 2004;40: 725A.
46. Sama SK, Bhargawa S, Gopinath N et al. Non-cirrhotic portal fibrosis. Am J Med. 1971;51: 160-169.
47. Okuda K, Obata H. Idiopathic portal hypertension. In: Okuda K, Benhamou J-P (eds). Portal Hypertension. Tokyo, Springer-Verlag, 1992; 223-240.
48. Hillaire S, Valla D, Lebrec D. Non-cirrhotic portal hypertension. Clin Liv Dis. 1997;1: 223-240.
49. Kiire CR. Controlled trial of propranolol to prevent recurrent variceal bleeding in patients with non-cirrhotic portal fibrosis. Br Med J. 1989;298:1363-1365.
50. Shiha G, Hamid H, AskalanyHet al. Mononitrates and combination of mononitrates plus propranolol as adjuvants to sclerotherapy for the prevention of rebleeding from esophageal varices (abstract). Digestion. 1998;59 (suppl3); 340:2512.
51. Fakhry S, Omar M, Al GannamMet al. Endoscopic sclerotherapy versus endoscopic variceal ligation in the management of bleeding esophageal varices: a prospective randomised study in schistosomal hepatic fibrosis. Endoscopy Arab Edition. 2000;1: 39-44.
52. Elsayed SS, Shiha G, HamidMet al. Sclerotherapy versus sclerotherapy and propranolol in the prevention of rebleeding from esophageal varcies: a randomised study. Gut. 1996;38: 770-774.
53. Shiha G, Menesy A, Seef S et al. Endoscopic ligation compared with propranolol and combined isosorbide mononitrates (ISMN) and propranolol to prevent recurrent variceal bleeding: a prospective randomised trial (abstract). Gut. 2005;54: A6 021.
54. Thakeb F, Salama Z, Salama H et al. The value of combined use of N-butyl1-2 cyanoacrylate and ethanolamine oleate in the management of bleeding oesophagogastric varices. Endoscopy. 1995;27: 358-364.
55. Shiha G, Elsayed SS. Gastric variceal ligation: a new technique. Gastrointest Endosc. 1999;49: 437-441.
56. Rikkers LF, Sorrell WT, Jin G. Which portosystemic shunt is best? Gastroenterol Clin North Am. 1992;21: 179.
57. Salam AA, Ezzat FA, Aabu-Elmagd KM. Selective shunt in shistosomiasis in Egypt. Am J Surg. 1990;160: 90-92.
58. Gawish Y, El-Hammadi HA, Kotb M et al. Devascularization procedure and DSRS: a controlled randomised trial on selected haemodynamic portal flow pattern in schistosomal portal hypertension with variceal bleeding. Int Surg. 2000;85: 325-330.
59. Chwala YK, Dilawari JB, Dhimon RK et al. Schlerotherapy in non-cirrhotic portal fibrosis. Dig Dis Sci. 1997;42: 1449-1453.
60. Kahn D, Terblanche J, Kitano S et al. Injection sclerotherapy in adult patients with extrahepatic portal venous obstruction. Br J Surg. 1987;74: 600-602.
61. Sarin SK, Nanda R, Gaur Sk et al. Repeated endoscopic sclerotherapy for active varicel bleeding. Ann Surg. 1985;202: 708-711.
62. Sarin SK, Lahoti D, Saxena SP et al. Prevalence, classification and natural history of gastric varices: long term follow-up study on 568 patients with portal hypertension. Hepatology. 1992;16: 1343-1349.
63. Sarin SK. Non-cirrhotic portal fibrosis. Gut. 1989;30: 406-415.
64. Hou MC, Lin HC, Liu TT et al. Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomised trial. Hepatology. 2004;39: 746-753.
65. McKiernan PJ, Beath SV, Davison SM. A prospective study of endoscopic esophageal variceal ligation using a multiband ligator. J Pediatr Gastroenterol Nutr. 2002;34: 207-211.
66. Lee MS, Chou JY, Cheon YK et al. Use of detachable snares and elastic bands for endoscopic control of bleeding from large gastric varices. Gastrointest Endosc. 2002;56: 83-88.
67. Lo GH, Lai KH, Cheng JS et al. A prospective, randomised trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices. Hepatology. 2001;33: 1060-1064.
68. Sarin SK, Jain AK, Jain M et al. A randomised controlled trial of cyanoacrylate versus alcohol injection in patients with isolated fundic varices. Am J Gastroenterol. 2002;97: 1010-1015.
69. Williams SJG, Peters RA, Westaby D. Thrombin - an effective treatment for gastric variceal haemorrhage. Gut. 1994;35: 1287-1289.
70. Heneghan MA, Byrne A, Harrison PM. An open pilot study of the effects of a human fibrin glue for endoscopic treatment of patients with acute bleeding from gastric varices. Gastrointest Endosc. 2002;56: 422-426.
71. Yang WL, Tripathi D, Therapondos G et al. Endoscopic use of human thrombin in bleeding gastric varices. Am J Gastroenterol. 2002;97: 1381-1385.
72. Chau TN, Patch D, Chan YW et al. 'Salvage' transjugular intrahepatic portosystemic shunts: gastric fundal compared with esophageal variceal bleeding. Gastroenterology. 1998;114: 981-987.
73. Barabge K, Péron JM, Imani K et al. Transjugular intrahepatic portosystemic shunt in the treatment of refractory bleeding from ruptured gastric varices. Hepatology. 1999;30: 1139-1143.
74. Tripathi D, Therapondos G, Jackson E et al. The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlations. Gut. 2002;51:270-274.
75. Stanley AJ, Jalan R, Ireland HM, Hayes PC et al. A comparison between gastric and oesophageal variceal haemorrhage treated with transjugular portosystemic stent shunt (TIPSS). Aliment Pharmacol Ther. 1997;11: 171-176.
76. Wu CY, Yeh HZ, Chen GH. Pharmacologic efficacy in gastric variceal rebleeding and survival. J Clin Gastroenterol. 2002;35: 127-132.
77. Kitamoto M, Imamura M, Kamada K et al. Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage. AJR. 2002;178: 1167-1174.
78. Thomas PG, D'Cruz AJ. Distal splenorenal shunting for bleeding gastric varices. Br J Surg. 1994;81: 241-244.
79. Tomikawa M, Hashizumi M, Saku M et al. Effectiveness of gastric devascularization and splenectomy for patients with gastric varices. J Am Coll Surg. 2000;191: 498-503.
80. Han HS, Yi NJ, Kim YW et al. New operative method for fundal variceal bleeding: Fundectomy with periesophagogastric devascularization. World J Surg. 2004;28: 406-410.
81. Hsieh JS, Wang WM, Perng DS et al. Modified devascularization surgery for isolated gastric varices assessed by endoscopic ultrasonography. Surg Endosc. 2004;18: 666-671.
82. Trevino HH, Brady CE III, Schenker S. Portal hypertensive gastropathy. Dig Dis Sci. 1996;14: 258-270.
83. Panes J, Casadevall M, Fernandez M et al. Gastric microcirculatory changes of portal-hypertensive rats can be attenuated by long-term estrogen-progestagen treatment. Hepatology. 1994;20: 1261-1270.
84. Panes J, Bordas JM, Pique JM et al. Effects of propranolol on gastric mucosal perfusion in cirrhotic patients with portal hypertensive gastropathy. Hepatology. 1993;17: 213-218.
85. Payen JL, Cales P, Pienkowski P et al. Weakness of mucosal barrier in portal hypertensive gastropathy of alcoholic cirrhosis. Effects of propranolol and enprostil. J Hepatol. 1995;23: 689-696.
86. Shigemori H, Iwao T, IkegamiMet al. Effects of propranolol on gastric mucosal perfusion and serum gastrin level in cirrhotic patients with portal hypertensive gastropathy. Dig Dis Sci. 1994;39: 2433-2438.
87. Hosking SW, Kennedy HJ, Seddon I et al. The role of propranolol in congestive gastropathy of portal hypertension. Hepatology. 1987;7: 437-441.
88. Perez-Ayuso RM, Pique JM, Bosch J et al. Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis. Lancet. 1991;337: 1431-1434.
89. Kamath PS, Lacerda M, Ahlquist DA et al. Gastric mucosal responses to intrahepatic portosystemic shunting in patients with cirrhosis. Gastroenterology. 2000;118: 905-911.
90. Orloff MJ, Orloff MS, Orloff SL et al. Treatment of bleeding from portal hypertensive gastropathy by portacaval shunt. Hepatology. 1995;21: 1011-1017.
91. Urata J, Yamashita Y, Tsuchigame T et al. The effects of transjugular intrahepatic portosystemic shunt on portal hypertensive gastropathy. J Gastroenterol Hepatol. 1998;13: 1061-1067.
92. Gostout CJ, Ahlquist DA, RadfordCMet al. Endoscopic laser therapy for watermelon stomach. Gastroenterology. 1989;96: 1462-1465.
93. Tsai HH, Smith J, Danesh BJ. Successful control of bleeding from gastric antral vascular ectasia (watermelon stomach) by laser photocoagulation. Gut. 1991;32:93-94.
94. Bjorkman DJ, Buchi KN. Endoscopic laser therapy of the watermelon stomach. Lasers Surg Med. 1992;12: 478-481.
95. Lingenfelser T, Mueller M, Marks IN et al. Endoscopic laser therapy in a case of gastric antral vascular ectasia (watermelon stomach). Z Gastroenterol. 1993;31:322-324.
96. Potamiano S, Carter CR, Anderson JR. Endoscopic laser treatment of diffuse gastric antral vascular ectasia. Gut. 1994;35: 461-463.
97. González-Suárez B, Monfort D, Piqueras M et al. Endoscopic treatment with argon plasma coagulation for portal hypertensive gastropathy with no response to pharmacological therapy. (abstract) J Hepatol. 2003;38(185A): 59.
98. D'Amico G, de Franchis R and a cooperative study group. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators. Hepatology. 2003;38: 599-612.
99. Narahara Y, Kanazawa H, Kawamata H et al. A randomised clinical trial comparing transjugular intrahepatic portosystemic shunt with endoscopic. Hepatol Resl. 2001;21: 189-198.
100. Gulberg V, Schepke M, Geigenberger G et al. Transjugular intrahepatic portosystemic shunting is not superior to endoscopic variceal band ligation for prevention of variceal rebleeding in cirrhotic patients: a randomised controlled trial. Scand J Gastroenterol. 2002;37: 338-343.
101. Escorsell A, Banares R, Garcia-Pagan JC et al. TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomised controlled trial. Hepatology. 2002;35: 385-392.
102. Papatheodoris GV, Goulis J, Leandro G et al. Transjugular intrahepatic portoystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: a meta-analysis. Hepatology. 1999;30: 612-622.
103. Luca A, D'Amico G, La Galla R et al. TIPS for prevention of recurrent bleeding in patients with cirrhosis: meta-analysis of randomised clinical trials. Radiology. 1999;212: 411-421.
104. Burroughs AK, Vangeli M. Transjugular intrahepatic portosystemic shunt versus endoscopic therapy: randomised trials for secondary prophylaxis of variceal bleeding: an updated meta-analysis. Scand J Gastroenterol. 2002;37: 249-252.
105. Bureau C, Garcia-Pagan JC, Pomier-Layrargues G et al. The use of polytetrafluoroethylene (PTFE) covered stents improve the patency of TIPS: results of a randomised study (abstract). Hepatology. 2002;36: 1554.