FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo

BMC Molecular Biology

Volumn 9, Issue , 2008, Pages

  Mali, Raghuveer S ^a   Peng, Guang Hua ^b   Zhang, Xiao ^a   Dang, Loan ^a   Chen, Shiming ^b   Mitton, Kenneth P ^a  

^a OAKLAND UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONE ROD HOMEOBOX PROTEIN; FLT 3 INTERACTING ZINC FINGER PROTEIN; HOMEODOMAIN PROTEIN; REGULATOR PROTEIN; RHODOPSIN; RNA POLYMERASE II; UNCLASSIFIED DRUG; FIZ1 PROTEIN, MOUSE; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE FUNCTION; IN VIVO STUDY; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTORECEPTOR CELL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; RETINA NERVE CELL; TRANSCRIPTION INITIATION; ANIMAL; CYTOLOGY; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; RETINA; ULTRASTRUCTURE;

MAMMALIA;

ANIMALS; HOMEODOMAIN PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NEURONS; PHOTORECEPTORS, VERTEBRATE; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RETINA; TRANS-ACTIVATORS;

EID: 54949104448     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-9-87     Document Type: Article

References (47)

1. Cepko CL Austin CP Yang X Alexiades M Ezzeddine D Cell fate determination in the vertebrate retina Proc Natl Acad Sci USA 1996, 93(2):589-595. 40096 8570600 10.1073/pnas.93.2.589
2. Bessant DA Payne AM Mitton KP Wang QL Swain PK Plant C Bird AC Zack DJ Swaroop A Bhattacharya SS A mutation in NRL is associated with autosomal dominant retinitis pigmentosa Nat Genet 1999, 21(4):355-356. 10.1038/ 7678 10192380
3. Freund CL Gregory-Evans CY Furukawa T Papaioannou M Looser J Ploder L Bellingham J Ng D Herbrick JA Duncan A et al. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor Cell 1997, 91(4):543-553. 10.1016/S0092-8674(00)80440-7 9390563
4. Mears AJ Kondo M Swain PK Takada Y Bush RA Saunders TL Sieving PA Swaroop A Nrl is required for rod photoreceptor development Nat Genet 2001, 29(4):447-452. 10.1038/ng774 11694879
5. Chen S Wang QL Xu S Liu Y Wang Y Zack DJ Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy Hum Mol Genet 2002, 11:873-884. 10.1093/hmg/11.8.873 11971869
6. Haider NB Jacobson SG Cideciyan AV Swiderski R Streb LM Searby C Beck G Hockey R Hanna DB Gorman S et al. Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate Nat Genet 2000, 24(2):127-131. 10.1038/72777 10655056
7. Peng GH Chen S Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation Hum Mol Genet 2007, 16(20):3433-3452. 17656371 10.1093/hmg/ddm200
8. Mitton KP Swain PK Chen S Xu S Zack DJ Swaroop A The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation J Biol Chem 2000, 275(38):29794-29799. 10.1074/jbc.M003658200 10887186
9. Peng GH Ahmad O Ahmad F Liu J Chen S The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes Hum Mol Genet 2005, 14(6):747-764. 10.1093/hmg/ddi070 15689355
10. Chen J Rattner A Nathans J The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes J Neurosci 2005, 25(1):118-129. 10.1523/JNEUROSCI.3571-04.2005 15634773
11. Mitton KP Swain PK Khanna H Dowd M Apel IJ Swaroop A Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: Possible role of Fiz1 as a transcriptional repressor Hum Mol Genet 2003, 12(4):365-373. 10.1093/hmg/ddg035 12566383
12. Wolf I Rohrschneider LR Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3 J Biol Chem 1999, 274(30):21478-21484. 10.1074/jbc.274.30.21478 10409713
13. Mali RS Zhang X Hoerauf W Doyle D Devitt J Loffreda-Wren J Mitton KP FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro Exp Eye Res 2007, 84(2):349-360. 10.1016/j.exer.2006.10.009 17141759
14. Goldberg AF Ritter LM Khattree N Peachey NS Fariss RN Dang L Yu M Bottrell AR An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis Invest Ophthalmol Vis Sci 2007, 48(7):2975-2986. 10.1167/iovs.07-0049 17591862
15. Altman LG Schneider BG Papermaster DS Rapid embedding of tissues in Lowicryl K4M for immunoelectron microscopy J Histochem Cytochem 1984, 32(11):1217-1223. 6436366
16. Lahiri DK Ge Y Electrophoretic mobility shift assay for the detection of specific DNA-protein complex in nuclear extracts from the cultured cells and frozen autopsy human brain tissue Brain Res Brain Res Protoc 2000, 5(3):257-265. 10.1016/S1385-299X(00)00021-0 10906491
17. Peng GH Chen S Chromatin immunoprecipitation identifies photoreceptor transcription factor targets in mouse models of retinal degeneration: new findings and challenges Vis Neurosci 2005, 22(5):575-586. 10.1017/ S0952523805225063 16332268
18. Carter-Dawson LD LaVail MM Sidman RL Differential effect of the rd mutation on rods and cones in the mouse retina Invest Ophthalmol Vis Sci 1978, 17(6):489-498. 659071
19. Bowes C Li T Danciger M Baxter LC Applebury ML Farber DB Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase Nature 1990, 347(6294):677-680. 10.1038/ 347677a0 1977087
20. Cheng H Khanna H Oh EC Hicks D Mitton KP Swaroop A Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors Hum Mol Genet 2004, 13(15):1563-1575. 10.1093/hmg/ddh173 15190009
21. Rehemtulla A Warwar R Kumar R Ji X Zack DJ Swaroop A The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression Proc Natl Acad Sci USA 1996, 93(1):191-195. 40204 8552602 10.1073/pnas.93.1.191
22. Akimoto M Filippova E Gage PJ Zhu X Craft CM Swaroop A Transgenic mice expressing Cre-recombinase specifically in M- or S-cone photoreceptors Invest Ophthalmol Vis Sci 2004, 45(1):42-47. 10.1167/iovs.03-0804 14691152
23. Labhart P Karmakar S Salicru EM Egan BS Alexiadis V O'Malley BW Smith CL Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator Proc Natl Acad Sci USA 2005, 102(5):1339-1344. 547886 15677324 10.1073/pnas.0409578102
24. Ferguson GD Jensen-Pergakes K Wilkey C Jhaveri U Richard N Verhelle D De Parseval LM Corral LG Xie W Morris CL et al. Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2 J Clin Immunol 2007, 27(2):210-220. 10.1007/ s10875-007-9070-6 17308870
25. Alexiadis V Ballestas ME Sanchez C Winokur S Vedanarayanan V Warren M Ehrlich M RNAPol-ChIP analysis of transcription from FSHD-linked tandem repeats and satellite DNA Biochim Biophys Acta 2007, 1769(1):29-40. 1802126 17239456
26. Krishnamurthy S He X Reyes-Reyes M Moore C Hampsey M Ssu72 Is an RNA polymerase II CTD phosphatase Mol Cell 2004, 14(3):387-394. 10.1016/ S1097-2765(04)00235-7 15125841
27. Palancade B Bellier S Almouzni G Bensaude O Incomplete RNA polymerase II phosphorylation in Xenopus laevis early embryos J Cell Sci 2001, 114(Pt 13):2483-2489. 11559756
28. Waterston RH Lindblad-Toh K Birney E Rogers J Abril JF Agarwal P Agarwala R Ainscough R Alexandersson M An P et al. Initial sequencing and comparative analysis of the mouse genome Nature 2002, 420(6915):520-562. 10.1038/nature01262 12466850
29. Treisman J Gonczy P Vashishtha M Harris E Desplan C A single amino acid can determine the DNA binding specificity of homeodomain proteins Cell 1989, 59(3):553-562. 10.1016/0092-8674(89)90038-X 2572327
30. Baird-Titus JM Clark-Baldwin K Dave V Caperelli CA Ma J Rance M The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site J Mol Biol 2006, 356(5):1137-1151. 10.1016/j.jmb.2005.12.007 16406070
31. Chaney BA Clark-Baldwin K Dave V Ma J Rance M Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome Biochemistry 2005, 44(20):7497-7511. 10.1021/ bi0473253 15895993
32. Swain PK Hicks D Mears AJ Apel IJ Smith JE John SK Hendrickson A Milam AH Swaroop A Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors J Biol Chem 2001, 276(39):36824-36830. 10.1074/ jbc.M105855200 11477108
33. Helmlinger D Hardy S Abou-Sleymane G Eberlin A Bowman AB Gansmuller A Picaud S Zoghbi HY Trottier Y Tora L et al. Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction PLoS Biol 2006, 4(3):e67. 1382020 16494529 10.1371/journal.pbio.0040067
34. Wang X Xu S Rivolta C Li LY Peng GH Swain PK Sung CH Swaroop A Berson EL Dryja TP et al. Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function J Biol Chem 2002, 277(45):43288-43300. 10.1074/jbc.M207952200 12215455
35. Lerner LE Peng GH Gribanova YE Chen S Farber DB Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx J Biol Chem 2005, 280(21):20642-20650. 10.1074/jbc.M500957200 15781457
36. Leu S Ouyang P Spatial and temporal expression profile of pinin during mouse development Gene Expr Patterns 2006, 6(6):620-631. 10.1016/ j.modgep.2005.11.009 16427813
37. Fossat N Le Greneur C Beby F Vincent S Godement P Chatelain G Lamonerie T A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors BMC Dev Biol 2007, 7:122. 2204009 17980036 10.1186/1471-213X-7-122
38. Oh EC Khan N Novelli E Khanna H Strettoi E Swaroop A Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL Proc Natl Acad Sci USA 2007, 104(5):1679-1684. 1780067 17242361 10.1073/pnas.0605934104
39. Corbo JC Cepko CL A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome PLoS Genet 2005, 1(2):e11. 1186732 16110338 10.1371/journal.pgen.0010011
40. Kerppola TK Curran T Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun Oncogene 1994, 9(3):675-684. 8108109
41. Kumar R Chen S Scheurer D Wang QL Duh E Sung CH Rehemtulla A Swaroop A Adler R Zack DJ The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures J Biol Chem 1996, 271(47):29612-29618. 10.1074/jbc.271.47.29612 8939891
42. Chen S Wang QL Nie Z Sun H Lennon G Copeland NG Gilbert DJ Jenkins NA Zack DJ Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes Neuron 1997, 19(5):1017-1030. 10.1016/S0896-6273(00)80394-3 9390516
43. Chau KY Chen S Zack DJ Ono SJ Functional domains of the cone-rod homeobox (CRX) transcription factor J Biol Chem 2000, 275(47):37264-37270. 10.1074/jbc.M002763200 10984472
44. Bowes C van Veen T Farber DB Opsin, G-protein and 48-kDa protein in normal and rd mouse retinas: Developmental expression of mRNAs and proteins and light/dark cycling of mRNAs Exp Eye Res 1988, 47(3):369-390. 10.1016/0014-4835(88)90049-8 2846333
45. Lem J Krasnoperova NV Calvert PD Kosaras B Cameron DA Nicolo M Makino CL Sidman RL Morphological, physiological, and biochemical changes in rhodopsin knockout mice Proc Natl Acad Sci USA 1999, 96(2):736-741. 15206 9892703 10.1073/pnas.96.2.736
46. Guenther MG Levine SS Boyer LA Jaenisch R Young RA A chromatin landmark and transcription initiation at most promoters in human cells Cell 2007, 130(1):77-88. 10.1016/j.cell.2007.05.042 17632057
47. Timmers AM Newton BR Hauswirth WW Synthesis and stability of retinal photoreceptor mRNAs are coordinately regulated during bovine fetal development Exp Eye Res 1993, 56(3):257-265. 10.1006/exer.1993.1034 8386100