Genotoxic effects of X-rays on keratinized mucosa cells during panoramic dental radiography

Dentomaxillofacial Radiology

Volumn 37, Issue 7, 2008, Pages 398-403

  Cerqueira, Encida De Moraes Marcilio ^a,c   Meireles, J R C ^a   Lopes, M A ^a   Junqueira, V C ^a   Gomes Filho, I S ^a   Trindade, S ^a   Machado Santelli, G M ^b  

^a DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c NONE   (Brazil)

Author keywords

Internal resorption; Micro computed tomography; Quantitative measurement; Scanning electron confocal microscopy

Indexed keywords

ADULT; APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CHROMOSOME DAMAGE; CYTOLOGY; DIAGNOSTIC PROCEDURE; EPITHELIUM CELL; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; KERATINIZATION; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MUCOSA CELL; QUESTIONNAIRE; TOOTH RADIOGRAPHY; X RAY;

ADULT; CELL NUCLEUS; CHROMOSOMES; DNA DAMAGE; FEMALE; HUMANS; KERATINOCYTES; MALE; MICRONUCLEUS TESTS; MOUTH MUCOSA; QUESTIONNAIRES; RADIOGRAPHY, PANORAMIC; X-RAYS; YOUNG ADULT;

EID: 54849426675     PISSN: 0250832X     EISSN: None     Source Type: Journal    
DOI: 10.1259/dmfr/56848097     Document Type: Article

References (42)

1. Moore LE, Warner ML, Smith AH, Kaiman D, Smith MT. Use of the fluorescent micronucleus test to detect the genotoxic effects of radiation and arsenic exposure in exfoliated human epithelial cells. Environ Mol Mutagen 1996; 627: 176-184.
2. Natarajan AT. Chromosomal aberrations: past, present and future. Mutat Res 2002; 504: 3-16.
3. Obe G, Pfeiffer P, Savage JR, Johannes C, Goedecke W, Jeppesen P, et al. Chromosomal aberrations: formation, identification and distribution. Mutat Res 2002; 504: 17-36.
4. Pastor S, Gutiérrez S, Creus A, Cebulska-Wasilewska, Marcos R. Micronuclei in peripheral lymphocytes and buccal epithelial cells of Polish farmers exposed to pesticides. Mutat Res 2001; 495: 147-156.
5. Angelini S, Kumarb R, Carbonea F, Maffeia F, Fortia GC, Violanteb FS, et al. Micronuclei in humans induced by exposure to low level of ionizing radiation: influence of polymorphisms in DNA repair genes. Mutat Res 2005; 570: 105-117.
6. Heddle JA, Hite M, Kirkhart B, Mavournin K, Macgregor JT, Newell GW, et al. The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res 1983; 123: 61-118.
7. Tolbert PE, Shy CM, Allen JW. Micronuclei and other nuclear anomalies in buccal smears: a field test in snuff users. Am J Epidemiol 1991; 134: 840-850.
8. Tolbert PE, Shy CM, Allen JW. Micronuclei and other nuclear anomalies in buccal smears: methods development. Mutat Res 1992; 271: 69-77.
9. Cerqueira EMM, Gomes-Filho IS, Trindade S, Lopes MA, Passos JS, Machado-Santelli GM. Genetic damage in exfoliated cells from oral mucosa of individuals exposed to X-rays during panoramic dental radiographies. Mutat Res 2004; 562: 111-117.
10. Popova L, Hishkilova D, Hadjidekova V, Hristova R, Atanasova P, Ziya D. Micronucleus test in buccal epithelium cells from patients subjected to panoramic radiography. Dentomaxillofac Radiol 2007; 36: 168-171.
11. Angelieri F, Oliveira GR, Sannomiya EK, Ribeiro DA. DNA damage and cellular death in oral mucosa cells of children who have undergone panoramic dental radiography. Pediatr Radiol 2007; 37: 561-565.
12. Bragança-Pereira CA. Teste estatístico para comparer proporções em problemas de citogenética. In: Rabello-Gay MN, Rodrigues MALR, Monteleone Neto R (ed). Mutagênese, carcinogênese e teratogênese: métodos e critérios de avaliação. Ribeirão Preto: Sociedade Brasileira de Genética, 1991, pp 113-121.
13. Kalbfleish JG. Probability and statistical inference. New York, NY: Springer-Verlag, 1985.
14. Stich HF, Rosin MP. Micronuclei in exfoliated human cells as an internal dosimeter for exposures to carcinogens. Carcinogens and mutagens in the environment. Boca Raton, FL: CRC Press, 1983, pp 17-25.
15. Sarto F, Tomanin R, Giacomelli L, Canova A, Raimondi F, Ghiotto C, et al. Evaluation of chromosomal aberrations in lymphocytes, oral mucosa and hair root cells of patients under antiblastic therapy. Mutat Res 1990; 228: 157-169.
16. Fenech M, Holland N, Chang WP, Zeiger E, Bonassi S. The human micronucleus project: an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res 1999; 428: 271-283.
17. Bolognesi C, Lando C, Forni A, Landini E, Scarpato R, Migliore L, et al. Chromosomal damage and ageing: effect on micronuclei frequency in peripheral blood lymphocytes. Age-Ageing 1999; 28: 393-397.
18. Bonassi S, Fenech M, Lando C, Lin Y. Ceppi M, Chang WP, et al. Human micronucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes. Part I. Effects of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ Mol Mutagen 2001; 37: 31-45.
19. Odagiri Y, Uchida H. Influence of serum micronutrients on the incident of kinetochore-positive or negative micronuclei in human peripheral blood lymphocytes. Mutat Res 1998; 415: 35-45.
20. Kahrahalil B, Karakaya A, Burgaz S. The micronucleus assay in exfoliated buccal cells: application to occupational exposure to polycyclic hydrocarbons. Mutat Res 1999; 442: 29-35.
21. Maffei F, Angelini S, Forti GC, Lodi V, Violante FS, Mattioli S, et al. Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis 2002; 17: 405-409.
22. Ishikawa H, Yamamoto H, Tian Y, Kawano M, Yamauchi T. Yokoyama K. Effects of ALDH2 gene polymorphisms and alcohol-drinking behavior on micronuclei frequency in non-smokers. Mutat Res 2003; 541: 9-16.
23. Burgaz S, Karahalil B, Bayrak P, Taskin L, Yavuzaslan F, Bökesoy I, et al. Urinary cyclophosphamide excretion and micronuclei frequencies in peripheral lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics. Mutat Res 1999; 439: 97-104.
24. Dietz J, Diehl AS, Prolla JC, Furtado CD, Furtado AD. Pesquisa de micronúcleos na mucosa esofágica e sua relação com fatores de risco ao câncer de esôfago. Ver ASS Med Brasil 2000; 46: 207-211.
25. Rajah TT, Ahuja YR. In vivo genotoxicity of alcohol consumption and lead exposure in printing press workers. Alcohol 1996; 13: 65-68.
26. Kassie F, Darroudi F, Kundi M, Schulte-Hermann R, Knasmuller S. Khat (Catha edullis) consumption causes genotoxic effects in humans. Int J Cancer 2001; 92: 329-332.
27. Ishikawa H, Miyatsy Y, Kurihara K, Yokoyama K. Gene-environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human lymphocytes. Mutat Res 2006; 594: 1-9.
28. Albrecht T, Deng CZ, Abdel-Rahman SZ, Fons M, Cindripini P, El Zein RA. Differential mutagen sensitivity of peripheral blood lymphocytes from smokers and nonsmokers: effect of human cytomegalovirus infection. Environ Mol Mutagen 2004; 43: 169-178.
29. Hoffmann H, Speit G. Assessment of DNA damage in peripheral blood of heavy smokers with the comet assay and the micronucleus test. Mutat Res 2005; 581: 105-114.
30. Freita VS, Lopes MA, Meireles JRC, Reis L, Cerqueira EMM. Efeitos genotóxicos de fatores considerados de risco para o cancer bucal. Revista Baiana de Saúde Pública 2005; 29: 189-199.
31. Little JB. Radiation carcinogenesis. Carcinogenesis 2000; 21: 397-404.
32. Cardoso RS, Takahashi-Hyodo S, Peitl Jr P, Ghilardi-Neto T, Sakamoto-Hojo ET. Evaluation of chromosomal aberrations, micronuclei and sister chromatid exchanges in hospital workers chronically exposed to ionizing radiation. Teratog Carcinog Mutagen 2001; 21: 431-439.
33. Jagetia GC, Jayakrishnan A, Fernandes D, Vidyasagar MS. Evaluation of micronuclei frequency in the cultured peripheral blood lymphocytes of cancer patients before and after radiation treatment. Mutat Res 2001; 491: 9-16.
34. Venkatachalam P, Paul SFD, Prabhu BK, Mohankumar MN, Jeevanram RK. Comparison of chronic exposures received by radiation workers using different biological end-points with the doses recorded by TLD. Australas Radioal 2001; 45: 464-471.
35. Sari-Monodier I, Orsière T, Bellon L, Pompili J, Sapin C, Botta A. Cytogenetic monitoring of industrial radiographers using the micronucleus assay. Mutat Res 2002; 521: 37-46.
36. Barcellos-Hoff MH. Interactive radiation carcinogenesis: interactions between call and tissue responses to DNA damage. Sem Cancer Biology 2005; 15: 138-148.
37. Torres-Bugarín O, Anda-Casillas A, Ramírez-Muñoz MP, Sánches-Corona J, Cantú JM, Zúñiga G. Determination of diesel genotoxicity in firebreathers by micronuclei and nuclear abnormalities in buccal mucosa. Mutat Res 1998; 413: 277-281.
38. Revazova J, Yurchenko V, Katosova L, Platonova V, Sycheva L, Khripach L, et al. Cytogenetic investigation of women exposed to different levels of dioxins in Chapaevsk town. Chemosphere 2001; 43: 999-1004.
39. Serrano-Garcia L, Montero-Montoya R. Micronuclei and chromatid buds are the result of related genotoxic events. Environ Mol Mutagen 2001; 38: 38-45.
40. Torres-Bugarin O, Ventura-Aguilar A, Zamora-Perez A, Gómez-Medab BC, Ramos-Ibarra ML, Morgan-Villella G, et al. Evaluation of cisplatin + 5-FU, carboplatin +5FU, and ifosfamide + epirubicine regiments using the micronuclei test and nuclear abnormalities in the buccal mucosa. Mutat Res 2001; 565: 91-101.
41. Bohrer PL, Filho MS, Paiva RL, Da Silva IL, Rados PV. Assessment of micronucleus frequency in normal oral mucosa of patients exposed to carcinogens. Acta Cytol 2005; 49: 265-272.
42. Nersesyan A. The nature of "broken-eggs" events in exfoliated human cells. Acta Cytol 2006; 50: 598 (Letter).