New retinoid chemotypes: 9-cis-Retinoic acid analogs with hydrophobic rings derived from terpenes as selective RAR agonists

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 22, 2008, Pages 9719-9728

  Álvarez, Susana ^a   Pazos Randulfe, Yolanda ^a   Khanwalkar, Harshal ^b   Germain, Pierre ^b   Álvarez, Rosana ^a   Gronemeyer, Hinrich ^b   de Lera, Ángel R ^a  

^a UNIVERSITY OF VIGO   (Spain)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

9 cis Retinoic acid; Agonist; Nuclear receptors; RAR; Retinoids; RXR

Indexed keywords

ALITRETINOIN; ALITRETINOIN DERIVATIVE; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID X RECEPTOR; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; RABIES VIRUS; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

HYDROPHOBICITY; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; STEREOISOMERISM; TERPENES; TRETINOIN;

EID: 54849422856     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.09.069     Document Type: Article

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