Separation and identification of trinucleotide-melphalan adducts from enzymatically digested DNA using HPLC-ESI-MS

Analytical and Bioanalytical Chemistry

Volumn 392, Issue 5, 2008, Pages 805-817

  Mohamed, Dalia ^a   Linscheid, Michael ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

DNA adducts; Fragmentation; LC MS MS; Melphalan; Nitrogen mustards

Indexed keywords

CARCINOGENS; ELECTROSPRAY IONIZATION; EXTRACTION; GENES; HYDROCARBONS; MASS SPECTROMETRY; MUTAGENS; NITROGEN COMPOUNDS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; ORGANIC ACIDS; SEPARATION;

DNA ADDUCTS; FRAGMENTATION; LC-MS-MS; MELPHALAN; NITROGEN MUSTARDS;

DNA;

ALKYLATING AGENT; AZIRIDINE DERIVATIVE; CALF THYMUS DNA; CHLORMETHINE DERIVATIVE; CROSS LINKING REAGENT; DEOXYRIBONUCLEASE; DEOXYRIBONUCLEOTIDE; DNA; MELPHALAN; NUCLEASE S1; RIBONUCLEASE; SERRATIA MARCESCENS NUCLEASE;

ALKYLATION; CHEMISTRY; CONFERENCE PAPER; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; TIME;

ALKYLATION; ANTINEOPLASTIC AGENTS, ALKYLATING; AZIRIDINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; DEOXYRIBONUCLEOTIDES; DNA; DNA ADDUCTS; ENDODEOXYRIBONUCLEASES; ENDORIBONUCLEASES; MELPHALAN; NITROGEN MUSTARD COMPOUNDS; SINGLE-STRAND SPECIFIC DNA AND RNA ENDONUCLEASES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

BRASSICACEAE;

EID: 54549125794     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-008-2236-0     Document Type: Conference Paper

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