Implications of enzymatic, acidic and thermal hydrolysis of DNA on the occurrence of cross-linked melphalan DNA adducts

Rapid Communications in Mass Spectrometry

Volumn 19, Issue 4, 2005, Pages 449-454

  Van Driessche, Bart Den ^a   Lemière, Filip ^a   Witters, Erwin ^a   Van Dongen, Walter ^a   Esmans, Eddy L ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSLINKING; ENZYMATIC HYDROLYSIS; NITROGEN;

ACIDIC CONDITIONS; ACIDIC HYDROLYSIS; ANTICANCER ACTIVITIES; CALF THYMUS; DNA ADDUCTS; IN-VIVO; MELPHALAN; NITROGEN MUSTARDS; REACTION CONDITIONS; THERMAL HYDROLYSIS;

DNA;

ADENINE; CALF THYMUS DNA; DNA; MELPHALAN; UNCLASSIFIED DRUG;

ACIDIFICATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CROSS LINKING; DNA ADDUCT; DNA CROSS LINKING; DNA STRAND; ENZYME ANALYSIS; ENZYME ASSAY; HYDROLYSIS; IN VIVO STUDY; NONHUMAN; REACTION ANALYSIS; REACTION OPTIMIZATION; THERMAL ANALYSIS;

EID: 13944281473     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1809     Document Type: Article

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