Effects of methotrexate on human bone cell responses to mechanical stimulation

Rheumatology

Volumn 43, Issue 10, 2004, Pages 1226-1231

  Elliot, K J ^b   Millward Sadler, S J ^b   Wright, M O ^b   Robb, J E ^a   Wallace, W H B ^a   Salter, Donald M ^b  

^a ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Gene expression; Integrin; Interleukin 1 ; Mechanical stimulation; Mechanotransduction; Methotrexate

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 1; CYTOKINE; INTEGRIN; INTERLEUKIN 1BETA; MESSENGER RNA; METHOTREXATE;

ARTICLE; BONE CELL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ELECTROPHYSIOLOGY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERPOLARIZATION; MEASUREMENT; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; TARGET CELL;

BONE AND BONES; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; COLLAGEN TYPE I; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTEGRINS; INTERLEUKIN-1; MEMBRANE POTENTIALS; METHOTREXATE; PHYSICAL STIMULATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 5444266726     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/keh296     Document Type: Article

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