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Volumn 4, Issue 5, 2004, Pages 745-757

Cladribine: From the bench to the bedside - Focus on hairy cell leukemia

Author keywords

Chronic lymphocytic leukemia; Cladribine; Cutaneous T cell lymphoma; Hairy cell leukemia; Langerhans cell histiocytosis; Low grade non Hodgkin's lymphoma; Purine analogs

Indexed keywords

ALPHA INTERFERON; BL 22; CD103 ANTIGEN; CD11 ANTIGEN; CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; CLADRIBINE; CYCLOPHOSPHAMIDE; IMMUNOTOXIN; IMMUNOTOXIN LMB2; INTERLEUKIN 2 RECEPTOR; PENTOSTATIN; PREDNISONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RITUXIMAB; UNCLASSIFIED DRUG;

EID: 5444258023     PISSN: 14737140     EISSN: None     Source Type: Journal    
DOI: 10.1586/14737140.4.5.745     Document Type: Review
Times cited : (12)

References (90)
  • 1
    • 0015515283 scopus 로고
    • Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity
    • Giblett ER, Anderson JE, Cohen F, Pollara B, Meuwissen HJ. Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. Lancet 2, 1067-1069 (1972).
    • (1972) Lancet , vol.2 , pp. 1067-1069
    • Giblett, E.R.1    Anderson, J.E.2    Cohen, F.3    Pollara, B.4    Meuwissen, H.J.5
  • 2
    • 3042870116 scopus 로고
    • Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo
    • Carson DA, Wasson DB, Kaye J et al. Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo. Proc. Natl Acad. Sci. USA 77, 6865-6869 (1980).
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 6865-6869
    • Carson, D.A.1    Wasson, D.B.2    Kaye, J.3
  • 3
    • 0020612685 scopus 로고
    • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes
    • Carson DA, Wasson DB, Taetle R, Yu A. Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes. Blood 62(4), 737-743 (1983).
    • (1983) Blood , vol.62 , Issue.4 , pp. 737-743
    • Carson, D.A.1    Wasson, D.B.2    Taetle, R.3    Yu, A.4
  • 4
    • 0026799508 scopus 로고
    • Cladribine (2-chlorodeoxyadenosine)
    • Beutler E. Cladribine (2-chlorodeoxyadenosine). Lancet 340, 952-956(1992).
    • (1992) Lancet , vol.340 , pp. 952-956
    • Beutler, E.1
  • 5
    • 0022003367 scopus 로고
    • Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes
    • Seto S, Carrera CJ, Kubota M, Wasson DB, Carson DA. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. J. Clin. Invest. 75(2), 377-383 (1985).
    • (1985) J. Clin. Invest. , vol.75 , Issue.2 , pp. 377-383
    • Seto, S.1    Carrera, C.J.2    Kubota, M.3    Wasson, D.B.4    Carson, D.A.5
  • 6
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y, Caspases: enemies within. Science 281, 1312-1316 (1998).
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 7
    • 0032483010 scopus 로고    scopus 로고
    • Induction of an apoptotic program in cell-free extracts by 2-chloro-2′-deoxyadenosine 5′-triphosphate and cytochrome c
    • Leoni LM, Chao Q, Cottam HB et al. Induction of an apoptotic program in cell-free extracts by 2-chloro-2′ -deoxyadenosine 5′-triphosphate and cytochrome c. Proc. Natl Acad. Sci. USA 95(16), 9567-9571 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.16 , pp. 9567-9571
    • Leoni, L.M.1    Chao, Q.2    Cottam, H.B.3
  • 8
    • 0038576220 scopus 로고    scopus 로고
    • A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2′-deoxyadenosine (Cladribine) and 2-chloroadenosine in human astrocytoma cells
    • Ceruti S, Beltrami E, Matarrese P et al. A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2′-deoxyadenosine (Cladribine) and 2-chloroadenosine in human astrocytoma cells. Mol. Pharmacol. 63, 1437-1447 (2003).
    • (2003) Mol. Pharmacol. , vol.63 , pp. 1437-1447
    • Ceruti, S.1    Beltrami, E.2    Matarrese, P.3
  • 9
    • 0034669944 scopus 로고    scopus 로고
    • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
    • Genini D, Adachi S, Chao Q et al. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood 96(10), 3537-3543 (2000).
    • (2000) Blood , vol.96 , Issue.10 , pp. 3537-3543
    • Genini, D.1    Adachi, S.2    Chao, Q.3
  • 10
    • 1642536316 scopus 로고    scopus 로고
    • The antileukemia drug 2-chloro-2′-deoxyadenosine: An intrinsic transcriptional antagonist
    • Hartman WR, Hentosh R The antileukemia drug 2-chloro-2′-deoxyadenosine: an intrinsic transcriptional antagonist. Mol. Pharmacol. 65, 227-234 (2004).
    • (2004) Mol. Pharmacol. , vol.65 , pp. 227-234
    • Hartman, W.R.1    Hentosh, R.2
  • 11
    • 0024796293 scopus 로고
    • Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo
    • Carrera CJ, Yamanaka H, Piro LD, Lotz M, Carson DA. Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. Adv. Exp. Med. Biol. 253B, 219-225 (1989).
    • (1989) Adv. Exp. Med. Biol. , vol.253 B , pp. 219-225
    • Carrera, C.J.1    Yamanaka, H.2    Piro, L.D.3    Lotz, M.4    Carson, D.A.5
  • 12
    • 0025724944 scopus 로고
    • Inhibitory effect of 2-chlorodeoxyadenosine on granulocytic, erythroid, and T-lymphocytic colony growth
    • Petzer AL, Bilgeri R, Zilian U et al. Inhibitory effect of 2-chlorodeoxyadenosine on granulocytic, erythroid, and T-lymphocytic colony growth. Blood 78(10), 2583-2587 (1991).
    • (1991) Blood , vol.78 , Issue.10 , pp. 2583-2587
    • Petzer, A.L.1    Bilgeri, R.2    Zilian, U.3
  • 14
    • 0025935563 scopus 로고
    • On the pharmacokinetics of 2-chloro-2′-deoxyadenosine in humans
    • Liliemark J, Juliusson G. On the pharmacokinetics of 2-chloro-2′-deoxyadenosine in humans. Cancer Res. 51(20), 5570-5572 (1991).
    • (1991) Cancer Res. , vol.51 , Issue.20 , pp. 5570-5572
    • Liliemark, J.1    Juliusson, G.2
  • 15
    • 0001514703 scopus 로고
    • Antileukemic and immunosuppressive activity of 2-chloro-2′-deoxyadenosine
    • Carson DA, Wasson DB, Beutler E. Antileukemic and immunosuppressive activity of 2-chloro-2′-deoxyadenosine. Proc. Natl Acad. Sci. USA 81, 2232-2236 (1984).
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 2232-2236
    • Carson, D.A.1    Wasson, D.B.2    Beutler, E.3
  • 16
    • 0027056958 scopus 로고
    • On the bioavailability of oral and subcutaneous 2-chloro-2′-deoxyadenosine in humans: Alternative routes of administration
    • Liliemark J, Albertioni F, Hassan M, Juliusson G. On the bioavailability of oral and subcutaneous 2-chloro-2′ -deoxyadenosine in humans: alternative routes of administration. J. Clin. Oncol. 10, 1514-1518 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1514-1518
    • Liliemark, J.1    Albertioni, F.2    Hassan, M.3    Juliusson, G.4
  • 17
    • 0027155584 scopus 로고
    • On the bioavalability of 2-chloro-2′-deoxyadenosine. The influence of food and omeprazole
    • Albertioni F, Juliusson G, Liliemark J. On the bioavalability of 2-chloro-2′-deoxyadenosine. The influence of food and omeprazole. Eur. J. Clin. Pharmacol. 44(6), 579-582 (1993).
    • (1993) Eur. J. Clin. Pharmacol. , vol.44 , Issue.6 , pp. 579-582
    • Albertioni, F.1    Juliusson, G.2    Liliemark, J.3
  • 18
    • 0029918664 scopus 로고    scopus 로고
    • Pharmacokinetic study of oral and bolus intravenous 2-chlorodeoxyadenosine in patients with malignancy
    • Saven A, Cheung WK, Smith I et al. Pharmacokinetic study of oral and bolus intravenous 2-chlorodeoxyadenosine in patients with malignancy. J. Clin. Oncol. 14(3), 978-983 (1996).
    • (1996) J. Clin. Oncol. , vol.14 , Issue.3 , pp. 978-983
    • Saven, A.1    Cheung, W.K.2    Smith, I.3
  • 19
    • 0013879521 scopus 로고
    • Hairy cells in blood lymphoreticular neoplastic disease and flagellated cells of normal lymph nodes
    • Shrek R. Donnelly J. Hairy cells in blood lymphoreticular neoplastic disease and flagellated cells of normal lymph nodes. Blood 27, 199 (1966).
    • (1966) Blood , vol.27 , pp. 199
    • Shrek, R.1    Donnelly, J.2
  • 20
    • 0038433145 scopus 로고
    • Die leukämische reticuloendotheliose
    • Ewald O. Die leukämische reticuloendotheliose. Deutsches Arch. Klin. Med. 142, 222-228 (1923).
    • (1923) Deutsches Arch. Klin. Med. , vol.142 , pp. 222-228
    • Ewald, O.1
  • 23
  • 25
    • 0032725388 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia-variant with cladribine
    • Tetreault SA, Robbins BA, Saven A. Treatment of hairy cell leukemia-variant with cladribine. Leuk. Lymphoma 35, 347-354 (1999).
    • (1999) Leuk. Lymphoma , vol.35 , pp. 347-354
    • Tetreault, S.A.1    Robbins, B.A.2    Saven, A.3
  • 27
    • 0025274664 scopus 로고
    • Lasting remissions in hairy cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine
    • Piro LD, Carrera CJ, Carson DA, Beutler E. Lasting remissions in hairy cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine. N. Engl. J. Med. 322, 1117-1121 (1990).
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1117-1121
    • Piro, L.D.1    Carrera, C.J.2    Carson, D.A.3    Beutler, E.4
  • 28
    • 0032530684 scopus 로고    scopus 로고
    • Long-term follow-up of patients with hairy cell leukemia after cladribine treatment
    • Saven A, Burian C, Koziol JA, Piro LD. Long-term follow-up of patients with hairy cell leukemia after cladribine treatment. Blood 92(6), 1918-1926 (1998).
    • (1998) Blood , vol.92 , Issue.6 , pp. 1918-1926
    • Saven, A.1    Burian, C.2    Koziol, J.A.3    Piro, L.D.4
  • 29
    • 0037362951 scopus 로고    scopus 로고
    • Extended follow-up of patients with hairy cell leukemia after treatment with cladribine
    • Goodman GR, Burian C, Koziol JA. Saven A. Extended follow-up of patients with hairy cell leukemia after treatment with cladribine. J. Clin. Oncol. 21(5), 891-896 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.5 , pp. 891-896
    • Goodman, G.R.1    Burian, C.2    Koziol, J.A.3    Saven, A.4
  • 30
    • 0029795202 scopus 로고    scopus 로고
    • Relapse of hairy cell leukemia after 2-chlorodeoxyadenosine: Long-term follow-up of the Northwestern University experience
    • Tallman MS, Hakimian D, Rademaker AW et al. Relapse of hairy cell leukemia after 2-chlorodeoxyadenosine: long-term follow-up of the Northwestern University experience. Blood 88(6), 1954-1959 (1996).
    • (1996) Blood , vol.88 , Issue.6 , pp. 1954-1959
    • Tallman, M.S.1    Hakimian, D.2    Rademaker, A.W.3
  • 31
    • 0031057250 scopus 로고    scopus 로고
    • Treatment of hairy-cell leukemia with cladribine: Response, toxicity, and long-term follow-up
    • Hoffman MA, Janson D, Rose E, Rai KR. Treatment of hairy-cell leukemia with cladribine: response, toxicity, and long-term follow-up. J. Clin. Oncol. 15, 1138-1142 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1138-1142
    • Hoffman, M.A.1    Janson, D.2    Rose, E.3    Rai, K.R.4
  • 32
    • 0031670669 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the Group C Protocol Mechanism of the National Cancer Institute: A report of 979 patients
    • Cheson BD, Sorensen JM, Vena DA et al. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the Group C Protocol Mechanism of the National Cancer Institute: a report of 979 patients. J. Clin. Oncol. 16(9), 3007-3015 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , Issue.9 , pp. 3007-3015
    • Cheson, B.D.1    Sorensen, J.M.2    Vena, D.A.3
  • 33
    • 0026513828 scopus 로고
    • Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA)
    • Estey EH, Kurzrock R, Kantarjian HM et al. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA). Blood 79(4), 882-887 (1992).
    • (1992) Blood , vol.79 , Issue.4 , pp. 882-887
    • Estey, E.H.1    Kurzrock, R.2    Kantarjian, H.M.3
  • 34
    • 0032842507 scopus 로고    scopus 로고
    • Long-term follow-up of patients with hairy cell leukaemia after treatment with pentostatin or cladribine
    • Dearden CE, Matutes E, Hilditch BL et al. Long-term follow-up of patients with hairy cell leukaemia after treatment with pentostatin or cladribine. Br. J. Haematol. 106, 515-519 (1999).
    • (1999) Br. J. Haematol. , vol.106 , pp. 515-519
    • Dearden, C.E.1    Matutes, E.2    Hilditch, B.L.3
  • 35
    • 0033047612 scopus 로고    scopus 로고
    • Long-term outcome of hairy cell leukemia treated with 2-chlorodeoxyadenosine
    • Jehn U, Bartl R, Dietzfelbinger H et al. Long-term outcome of hairy cell leukemia treated with 2-chlorodeoxyadenosine. Ann. Hematol. 78(3), 139-144 (1999).
    • (1999) Ann. Hematol. , vol.78 , Issue.3 , pp. 139-144
    • Jehn, U.1    Bartl, R.2    Dietzfelbinger, H.3
  • 36
    • 0033786707 scopus 로고    scopus 로고
    • Long-term follow-up of hairy cell leukemia patients treated with 2-chlorodeoxyadenosine
    • Zinzani PL, Magagnoli M, Bendandi M et al. Long-term follow-up of hairy cell leukemia patients treated with 2-chlorodeoxyadenosine. Haematologica 85(9), 922-925 (2000).
    • (2000) Haematologica , vol.85 , Issue.9 , pp. 922-925
    • Zinzani, P.L.1    Magagnoli, M.2    Bendandi, M.3
  • 37
    • 0032932661 scopus 로고    scopus 로고
    • 2-chlorodeoxyadenosine (cladribine) in the treatment of hairy cell leukemia and hairy cell leukemia variant: 7-year experience in Poland
    • Robak T, Blasinska-Morawiec M, Blonski J et al. 2-chlorodeoxyadenosine (cladribine) in the treatment of hairy cell leukemia and hairy cell leukemia variant: 7-year experience in Poland. Eur. J. Haematol. 62, 49-56 (1999).
    • (1999) Eur. J. Haematol. , vol.62 , pp. 49-56
    • Robak, T.1    Blasinska-Morawiec, M.2    Blonski, J.3
  • 38
    • 0036809024 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: A Phase II study
    • Van Rohr A, Schmitz SF, Tichelli A et al. Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a Phase II study. Ann. Oncol. 13(10 , 1641-1649 (2002).
    • (2002) Ann. Oncol. , vol.13 , Issue.10 , pp. 1641-1649
    • Van Rohr, A.1    Schmitz, S.F.2    Tichelli, A.3
  • 39
    • 0033561067 scopus 로고    scopus 로고
    • Filgrastim for cladribine-induced neutropenic fever in patients with hairy cell leukemia
    • Saven A, Burian C, Adusumalli J, Koziol JA. Filgrastim for cladribine-induced neutropenic fever in patients with hairy cell leukemia. Blood 93(8), 2471-2477 (1999).
    • (1999) Blood , vol.93 , Issue.8 , pp. 2471-2477
    • Saven, A.1    Burian, C.2    Adusumalli, J.3    Koziol, J.A.4
  • 41
    • 0026501106 scopus 로고
    • Rapid recovery from cytopenia in hairy cell leukemia after treatment with 2-chloro-2′-deoxyadenosine (CdA): Relation to opportunistic infections
    • Juliusson G, Liliemark J. Rapid recovery from cytopenia in hairy cell leukemia after treatment with 2-chloro-2′-deoxyadenosine (CdA): relation to opportunistic infections. Blood 79(4), 888-894 (1992).
    • (1992) Blood , vol.79 , Issue.4 , pp. 888-894
    • Juliusson, G.1    Liliemark, J.2
  • 42
    • 0028338450 scopus 로고
    • Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: Phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine
    • Juliusson G, Lenkei R, Liliemark J. Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine. Blood 83(12), 3672-3681 (1994).
    • (1994) Blood , vol.83 , Issue.12 , pp. 3672-3681
    • Juliusson, G.1    Lenkei, R.2    Liliemark, J.3
  • 43
    • 0031004465 scopus 로고    scopus 로고
    • Second cancer risk in hairy cell leukemia: Analysis of 350 patients
    • Kurzrock R, Strom SS, Estey E et al. Second cancer risk in hairy cell leukemia: analysis of 350 patients. J. Clin. Oncol. 15 (5), 1803-1810 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , Issue.5 , pp. 1803-1810
    • Kurzrock, R.1    Strom, S.S.2    Estey, E.3
  • 44
    • 0032529702 scopus 로고    scopus 로고
    • Second malignancies in patients with hairy cell leukemia in British Columbia: A 20-year experience
    • Au WY, Klasa RJ, Gallagher R, Le N, Gascoyne RD, Connors JM. Second malignancies in patients with hairy cell leukemia in British Columbia: a 20-year experience. Blood 92(4), 1160-1164 (1998).
    • (1998) Blood , vol.92 , Issue.4 , pp. 1160-1164
    • Au, W.Y.1    Klasa, R.J.2    Gallagher, R.3    Le, N.4    Gascoyne, R.D.5    Connors, J.M.6
  • 45
    • 0032812729 scopus 로고    scopus 로고
    • Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias
    • Cheson BD, Vena DA, Barrett J, Freidlin B. Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias. J. Clin. Oncol. 17(8), 2454-2460 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , Issue.8 , pp. 2454-2460
    • Cheson, B.D.1    Vena, D.A.2    Barrett, J.3    Freidlin, B.4
  • 47
    • 0025371574 scopus 로고
    • Epidemiology of hairy cell leukemia in Los Angeles
    • Bernstein L, Newton P, Ross RK Epidemiology of hairy cell leukemia in Los Angeles County. Cancer Res. 50, 3605-3609(1990).
    • (1990) County Cancer Res. , vol.50 , pp. 3605-3609
    • Bernstein, L.1    Newton, P.2    Ross, R.K.3
  • 48
    • 0036467659 scopus 로고    scopus 로고
    • Risk of second cancer in patients with hairy cell leukemia: Long-term follow-up
    • Federico M, Zinzani PL, Frassoldati A et al. Risk of second cancer in patients with hairy cell leukemia: long-term follow-up. J. Clin. Oncol. 20(3), 638-646 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.3 , pp. 638-646
    • Federico, M.1    Zinzani, P.L.2    Frassoldati, A.3
  • 49
    • 0029944385 scopus 로고    scopus 로고
    • Persistent clonal excess and skewed T-cell repertoire in T-cells from patients with hairy call leukemia
    • Kluin-Nelemans JC, Kester MG, Melenhorst JJ et al. Persistent clonal excess and skewed T-cell repertoire in T-cells from patients with hairy call leukemia. Blood 87, 3795-3802 (1996).
    • (1996) Blood , vol.87 , pp. 3795-3802
    • Kluin-Nelemans, J.C.1    Kester, M.G.2    Melenhorst, J.J.3
  • 51
    • 0028283984 scopus 로고
    • A single course of 2-chloro-deoxyadenosine does not eradicate leukemic cells in hairy cell leukemia patients in complete remission
    • Filleul B, Delannoy A, Ferrant A et al. A single course of 2-chloro-deoxyadenosine does not eradicate leukemic cells in hairy cell leukemia patients in complete remission. Leukemia 8(7), 1153-1156 (1994).
    • (1994) Leukemia , vol.8 , Issue.7 , pp. 1153-1156
    • Filleul, B.1    Delannoy, A.2    Ferrant, A.3
  • 52
    • 0027940204 scopus 로고
    • Immunomorphologic analysis of bone marrow biopsies after treatment with 2-chlorodeoxyadenosine for hairy cell leukemia
    • Ellison DJ, Sharpe RW, Robbins BA et al. Immunomorphologic analysis of bone marrow biopsies after treatment with 2-chlorodeoxyadenosine for hairy cell leukemia. Blood 84(12), 4310-4315 (1994).
    • (1994) Blood , vol.84 , Issue.12 , pp. 4310-4315
    • Ellison, D.J.1    Sharpe, R.W.2    Robbins, B.A.3
  • 53
    • 0030043304 scopus 로고    scopus 로고
    • Minimal residual disease may predict bone marrow relapse in patients with hairy cell leukemia treated with 2-chlorodeoxyadenosine
    • Wheaton S, Tallman MS, Hakimian D, Peterson L. Minimal residual disease may predict bone marrow relapse in patients with hairy cell leukemia treated with 2-chlorodeoxyadenosine. Blood 87(4), 1556-1560 (1996).
    • (1996) Blood , vol.87 , Issue.4 , pp. 1556-1560
    • Wheaton, S.1    Tallman, M.S.2    Hakimian, D.3    Peterson, L.4
  • 54
    • 0023111435 scopus 로고
    • Remissions in hairy-cell leukemia with pentostatin (2′ -deoxycoformycin)
    • Spiers AS, Moore D, Cassileth PA. Remissions in hairy-cell leukemia with pentostatin (2′-deoxycoformycin). N. Engl. J. Med. 316, 825-830 (1987).
    • (1987) N. Engl. J. Med. , vol.316 , pp. 825-830
    • Spiers, A.S.1    Moore, D.2    Cassileth, P.A.3
  • 55
    • 0027507810 scopus 로고
    • Complete remissions in hairy cell leukemia with 2-chlorodeoxyadenosine after failure with 2′-deoxycoformycin
    • Saven A, Piro LD. Complete remissions in hairy cell leukemia with 2-chlorodeoxyadenosine after failure with 2′-deoxycoformycin. Ann. Intern. Med. 119(4), 278-283 (1993).
    • (1993) Ann. Intern. Med. , vol.119 , Issue.4 , pp. 278-283
    • Saven, A.1    Piro, L.D.2
  • 56
    • 0034329819 scopus 로고    scopus 로고
    • Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin
    • Flinn IW, Kopecky KJ, Foucar MK et al. Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin. Blood 96(9 , 2981-2986 (2000).
    • (2000) Blood , vol.96 , Issue.9 , pp. 2981-2986
    • Flinn, I.W.1    Kopecky, K.J.2    Foucar, M.K.3
  • 57
    • 0025980309 scopus 로고
    • Pentostatin induces durable remissions in hairy cell leukemia
    • Cassileth PA, Cheuvart B, Spiers AS et al. Pentostatin induces durable remissions in hairy cell leukemia. J. Clin. Oncol. 9, 243-246 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , pp. 243-246
    • Cassileth, P.A.1    Cheuvart, B.2    Spiers, A.S.3
  • 58
    • 0042243678 scopus 로고    scopus 로고
    • Phase II study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia
    • Nieva J, Bethel K, Saven A. Phase II study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia. Blood 102(3), 810-813 (2003).
    • (2003) Blood , vol.102 , Issue.3 , pp. 810-813
    • Nieva, J.1    Bethel, K.2    Saven, A.3
  • 59
    • 0345689335 scopus 로고    scopus 로고
    • Rituximab in relapsed or refractory hairy cell leukemia
    • Thomas DA, O'Brien S, Bueso-Ramos C et al. Rituximab in relapsed or refractory hairy cell leukemia. Blood 102(12), 3906-3911 (2003).
    • (2003) Blood , vol.102 , Issue.12 , pp. 3906-3911
    • Thomas, D.A.1    O'Brien, S.2    Bueso-Ramos, C.3
  • 60
    • 0033571548 scopus 로고    scopus 로고
    • Responses in refractory hairy cell leukemia to a recombinant immunotoxin
    • Kreitman RJ, Wilson WH, Robbins D et al. Responses in refractory hairy cell leukemia to a recombinant immunotoxin. Blood 94(10), 3340-3348 (1999).
    • (1999) Blood , vol.94 , Issue.10 , pp. 3340-3348
    • Kreitman, R.J.1    Wilson, W.H.2    Robbins, D.3
  • 61
    • 0035954624 scopus 로고    scopus 로고
    • Efficacy of the antiCD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
    • Kreitman RJ, Wilson WH, Bergeron K et al. Efficacy of the antiCD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N. Engl. J. Med. 345 (4), 241-247 (2001).
    • (2001) N. Engl. J. Med. , vol.345 , Issue.4 , pp. 241-247
    • Kreitman, R.J.1    Wilson, W.H.2    Bergeron, K.3
  • 62
    • 0023758320 scopus 로고
    • 2-chlorodeoxyadenosine: An effective new agent for the treatment of chronic lymphocytic leukemia
    • Piro LD, Carrera CJ, Beutler E, Carson DA. 2-chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia. Blood 72(3), 1069-1073 (1988).
    • (1988) Blood , vol.72 , Issue.3 , pp. 1069-1073
    • Piro, L.D.1    Carrera, C.J.2    Beutler, E.3    Carson, D.A.4
  • 63
    • 0026347961 scopus 로고
    • 2-chlorodeoxyadenosine treatment of refractory chronic lymphocytic leukemia
    • Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD. 2-chlorodeoxyadenosine treatment of refractory chronic lymphocytic leukemia. Leuk. Lymphoma 5(Suppl.), 133-138 (1991).
    • (1991) Leuk. Lymphoma , vol.5 , Issue.SUPPL. , pp. 133-138
    • Saven, A.1    Carrera, C.J.2    Carson, D.A.3    Beutler, E.4    Piro, L.D.5
  • 64
    • 0027525929 scopus 로고
    • Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine
    • Kawasaki H, Carrera CJ, Piro LD, Saven A, Kipps TJ, Carson DA. Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood 81(3), 597-601 (1993).
    • (1993) Blood , vol.81 , Issue.3 , pp. 597-601
    • Kawasaki, H.1    Carrera, C.J.2    Piro, L.D.3    Saven, A.4    Kipps, T.J.5    Carson, D.A.6
  • 65
    • 0026675806 scopus 로고
    • Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine
    • Juliusson G, Elmhorn-Rosenborg A. Liliemark J. Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. N. Engl. J. Med. 327, 1056-1061 (1992).
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1056-1061
    • Juliusson, G.1    Elmhorn-Rosenborg, A.2    Liliemark, J.3
  • 66
    • 0027465143 scopus 로고
    • High complete remission rate from 2-chloro-2′-deoxyadenosine in previously treated patients with B-cell chronic lymphocytic leukemia: Response predicted by rapid decrease of blood lymphocyte count
    • Juliusson G, Liliemark J. High complete remission rate from 2-chloro-2′-deoxyadenosine in previously treated patients with B-cell chronic lymphocytic leukemia: response predicted by rapid decrease of blood lymphocyte count. J. Clin. Oncol. 11(4), 679-689 (1993).
    • (1993) J. Clin. Oncol. , vol.11 , Issue.4 , pp. 679-689
    • Juliusson, G.1    Liliemark, J.2
  • 67
    • 0027418888 scopus 로고
    • 2-chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine
    • Saven A, Lemon RH, Piro LD. 2-chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. N. Engl. J. Med. 328, 812-813 (1993).
    • (1993) N. Engl. J. Med. , vol.328 , pp. 812-813
    • Saven, A.1    Lemon, R.H.2    Piro, L.D.3
  • 68
    • 0028096165 scopus 로고
    • Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy
    • O'Brien S, Kantarjian H, Estey E et al. Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy. N. Engl. J. Med. 330, 319-322 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , pp. 319-322
    • O'Brien, S.1    Kantarjian, H.2    Estey, E.3
  • 69
    • 0028945716 scopus 로고
    • 2-chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia
    • Saven A, Lemon RH, Kosty M, Beutler E, Piro LD. 2-chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia. J. Clin. Oncol. 13(3), 570-574 (1995).
    • (1995) J. Clin. Oncol. , vol.13 , Issue.3 , pp. 570-574
    • Saven, A.1    Lemon, R.H.2    Kosty, M.3    Beutler, E.4    Piro, L.D.5
  • 70
    • 0034667537 scopus 로고    scopus 로고
    • Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: Report of a prospective, randomized, multicenter trial
    • Robak T, Blonski JZ, Kasznicki M. Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: report of a prospective, randomized, multicenter trial. Blood 96(8), 2723-2729 (2000).
    • (2000) Blood , vol.96 , Issue.8 , pp. 2723-2729
    • Robak, T.1    Blonski, J.Z.2    Kasznicki, M.3
  • 71
    • 0026590267 scopus 로고
    • 2-chlorodeoxyadenosine treatment of low-grade lymphomas
    • Kay AC, Saven A, Carrera CJ et al. 2-chlorodeoxyadenosine treatment of low-grade lymphomas. J. Clin. Oncol. 10(3), 371-377 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , Issue.3 , pp. 371-377
    • Kay, A.C.1    Saven, A.2    Carrera, C.J.3
  • 72
    • 0029163276 scopus 로고
    • 2-chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma
    • Saven A, Emanuele S, Kosty M, Koziol J, Ellison D, Piro L. 2-chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma. Blood 86(5), 1710-1716 (1995).
    • (1995) Blood , vol.86 , Issue.5 , pp. 1710-1716
    • Saven, A.1    Emanuele, S.2    Kosty, M.3    Koziol, J.4    Ellison, D.5    Piro, L.6
  • 73
    • 0037106369 scopus 로고    scopus 로고
    • Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: A Phase II study
    • Jäger G, Neumeister P, Brezinschek R et al. Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a Phase II study. J. Clin. Oncol. 20(18), 3872-3877 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.18 , pp. 3872-3877
    • Jäger, G.1    Neumeister, P.2    Brezinschek, R.3
  • 74
    • 2942578934 scopus 로고    scopus 로고
    • Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone
    • Armitage JO, Tobinai K, Hoelzer D, Rummel MJ. Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone. Int. J. Hematol. 79(4), 311-321 (2004).
    • (2004) Int. J. Hematol. , vol.79 , Issue.4 , pp. 311-321
    • Armitage, J.O.1    Tobinai, K.2    Hoelzer, D.3    Rummel, M.J.4
  • 75
    • 1842455198 scopus 로고    scopus 로고
    • Purine nucleoside analogs and combination therapies in B-cell chronic lymphocytic leukemia: Dawn of a new era
    • Nabhan C, Gartenhaus RB, Tallman MS. Purine nucleoside analogs and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era. Leuk. Res. 28(5), 429-442 (2004).
    • (2004) Leuk. Res. , vol.28 , Issue.5 , pp. 429-442
    • Nabhan, C.1    Gartenhaus, R.B.2    Tallman, M.S.3
  • 76
    • 0026723519 scopus 로고
    • 2-chlorodeoxyadenosine: An active agent in the treatment of cutaneous T-cell lymphoma
    • Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD. 2-chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma. Blood 80(3), 587-592 (1992).
    • (1992) Blood , vol.80 , Issue.3 , pp. 587-592
    • Saven, A.1    Carrera, C.J.2    Carson, D.A.3    Beutler, E.4    Piro, L.D.5
  • 77
    • 0028272475 scopus 로고
    • 2-chlorodeoxyadenosine therapy in patients with T-cell lymphoproliferative disorders
    • O'Brien S, Kurzrock R, Duvic M et al. 2-chlorodeoxyadenosine therapy in patients with T-cell lymphoproliferative disorders. Blood 84(3), 733-738 (1994).
    • (1994) Blood , vol.84 , Issue.3 , pp. 733-738
    • O'Brien, S.1    Kurzrock, R.2    Duvic, M.3
  • 78
    • 0030065140 scopus 로고    scopus 로고
    • Phase II trial of 2-chlorodeoxyadenosine for the treatment of cutaneous T-cell lymphoma
    • Kuzel TM, Hurria A, Samuelson E et al. Phase II trial of 2-chlorodeoxyadenosine for the treatment of cutaneous T-cell lymphoma. Blood 87(3), 906-911 (1996).
    • (1996) Blood , vol.87 , Issue.3 , pp. 906-911
    • Kuzel, T.M.1    Hurria, A.2    Samuelson, E.3
  • 79
    • 0037670799 scopus 로고    scopus 로고
    • Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma
    • Tobinai K, Uike N, Saburi Y et al. Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma. Int. J. Haematol. 77(5), 512-517 (2003).
    • (2003) Int. J. Haematol. , vol.77 , Issue.5 , pp. 512-517
    • Tobinai, K.1    Uike, N.2    Saburi, Y.3
  • 80
    • 0027492159 scopus 로고
    • Treatment of Waldenstrom macroglobulinemia with 2-chlorodeoxyadenosine
    • Dimopoulos MA, Kantarjian H, Estey E et al. Treatment of Waldenstrom macroglobulinemia with 2-chlorodeoxyadenosine. Ann. Intern. Med. 118(3), 195-198 (1993).
    • (1993) Ann. Intern. Med. , vol.118 , Issue.3 , pp. 195-198
    • Dimopoulos, M.A.1    Kantarjian, H.2    Estey, E.3
  • 81
    • 5444258021 scopus 로고    scopus 로고
    • Update of bolus administration of cladribine in the treatment of Waldenstrom's macroglobulinemia
    • Hampshire A, Saven A. Update of bolus administration of cladribine in the treatment of Waldenstrom's macroglobulinemia. Blood 102(11), 402a (2003).
    • (2003) Blood , vol.102 , Issue.11
    • Hampshire, A.1    Saven, A.2
  • 82
    • 0037396195 scopus 로고    scopus 로고
    • 2-chlorodeoxyadenosine alone and in combination for previously untreated Waldenstrom's macroglobulinemia
    • Weber DM, Dimopoulos MA, Delasalle K, Rankin K, Gavino M, Alexanian R. 2-chlorodeoxyadenosine alone and in combination for previously untreated Waldenstrom's macroglobulinemia. Semin. Oncol. 30(2), 243-247 (2003).
    • (2003) Semin. Oncol. , vol.30 , Issue.2 , pp. 243-247
    • Weber, D.M.1    Dimopoulos, M.A.2    Delasalle, K.3    Rankin, K.4    Gavino, M.5    Alexanian, R.6
  • 83
    • 0028221174 scopus 로고
    • Complete hematologic remissions in chronic-phase, Philadelphia-chromosome-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine
    • Saven A, Piro LD, Lemon RH et al. Complete hematologic remissions in chronic-phase, Philadelphia-chromosome-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine. Cancer 73(12), 2953-2963 (1994).
    • (1994) Cancer , vol.73 , Issue.12 , pp. 2953-2963
    • Saven, A.1    Piro, L.D.2    Lemon, R.H.3
  • 84
    • 0026536178 scopus 로고
    • 2-chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia
    • Santana VM, Mirro J, Kearns C, Schell MJ, Crom W, Blakley RL. 2-chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia. J. Clin. Oncol. 10(3), 364-370 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , Issue.3 , pp. 364-370
    • Santana, V.M.1    Mirro, J.2    Kearns, C.3    Schell, M.J.4    Crom, W.5    Blakley, R.L.6
  • 85
    • 0035366389 scopus 로고    scopus 로고
    • Experience with 2-chlorodeoxyadenosine in previously untreated children with newly diagnosed acute myeloid leukemia and myelodysplastic diseases
    • Krance RA, Hurwitz CA, Head DR et al. Experience with 2-chlorodeoxyadenosine in previously untreated children with newly diagnosed acute myeloid leukemia and myelodysplastic diseases. J. Clin. Oncol. 19(11), 2804-2811 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.11 , pp. 2804-2811
    • Krance, R.A.1    Hurwitz, C.A.2    Head, D.R.3
  • 86
    • 2342534391 scopus 로고    scopus 로고
    • Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, Phase III study
    • Holowiecki J, Grosicki S, Robak T et al. Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, Phase III study. Leukemia 18, 989-997 (2004).
    • (2004) Leukemia , vol.18 , pp. 989-997
    • Holowiecki, J.1    Grosicki, S.2    Robak, T.3
  • 87
    • 0027468268 scopus 로고
    • 2-chlorodeoxyadenosine dose escalation in nonhematologic malignancies
    • Saven A. Kawasaki H, Carrera CJ et al. 2-chlorodeoxyadenosine dose escalation in nonhematologic malignancies. J. Clin. Oncol. 11(4), 671-678 (1993).
    • (1993) J. Clin. Oncol. , vol.11 , Issue.4 , pp. 671-678
    • Saven, A.1    Kawasaki, H.2    Carrera, C.J.3
  • 88
    • 5444234837 scopus 로고    scopus 로고
    • Update of cladribine in the treatment of adults with Langerhans-cell histiocytosis (LCH)
    • Hampshire AP, Saven A. Update of cladribine in the treatment of adults with Langerhans-cell histiocytosis (LCH). Proc. Am. Soc. Clin. Oncol. 23, 581 (2004).
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23 , pp. 581
    • Hampshire, A.P.1    Saven, A.2
  • 89
    • 0032778769 scopus 로고    scopus 로고
    • Differential in situ cytokine profiles of Langerhans-like cells and T-cells in Langerhans cell histiocytosis: Abundant expression of cytokines relevant to disease and treatment
    • Egeler RM, Favara BE, van Meurs M, Laman JD, Claassen E. Differential in situ cytokine profiles of Langerhans-like cells and T-cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment. Blood 94(12), 4195-4201 (1999).
    • (1999) Blood , vol.94 , Issue.12 , pp. 4195-4201
    • Egeler, R.M.1    Favara, B.E.2    van Meurs, M.3    Laman, J.D.4    Claassen, E.5
  • 90
    • 0038639682 scopus 로고    scopus 로고
    • CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD
    • Nicolaou F, Teodoridis JM, Park H et al. CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood 101(10), 4033-4041 (2003).
    • (2003) Blood , vol.101 , Issue.10 , pp. 4033-4041
    • Nicolaou, F.1    Teodoridis, J.M.2    Park, H.3


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