Paraneoplastic limbic encephalitis: Diagnostic relevance of CSF analysis and total body PET scanning

Acta Neurologica Belgica

Volumn 104, Issue 2, 2004, Pages 57-63

  Dreessen, J ^a   Jeanjean, A P ^a   Sindic, C J M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Intrathecal immunity; Limbic encephalitis; Paraneoplastic antibodies; PET scan

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; ANTINUCLEAR ANTIBODY; CARBAMAZEPINE; CISPLATIN; EPIRUBICIN; FLUORODEOXYGLUCOSE F 18; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; METHYLPREDNISOLONE; PHENYTOIN; TETRACYCLINE; THYROXINE; VALPROIC ACID; VINCRISTINE;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; CASE REPORT; CAUSE OF DEATH; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; DEPRESSION; DIAGNOSTIC VALUE; DIPLOPIA; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOPATHOGENESIS; LUNG SMALL CELL CANCER; MALE; ORCHIECTOMY; OUTCOMES RESEARCH; PARANEOPLASTIC NEUROPATHY; POSITRON EMISSION TOMOGRAPHY; SEIZURE; SERODIAGNOSIS; SMOKING HABIT; TESTIS TUMOR; VERTIGO; WHOLE BODY TOMOGRAPHY;

EID: 5444245085     PISSN: 03009009     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Alamowitch S., Graus F., Uchuya M., René R., Bescansa E., Delattre J.-Y. Limbic encephalitis and small cell lung cancer; clinical and immunological features. Brain, 1997, 120 : 923-928.
2. Antione J. C., Cinotti L., Tilikete C., Bouhour F., Camdessanché P., Confavreux C., Vighetto A., Renault-Mannel V., Michel D., Honnorat J. Fluorodeoxyglucose 18 positron emission tomography in the diagnosis of cancer in patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Ann. Neurol., 2000, 48 : 105-108.
3. Bohnen N. I. L. J., Parnel K. J., Harper C. M. Reversible MRI findings in a patient with Hashimoto's encephalopathy. Neurology, 1997, 49 : 246-247.
4. Cinque P., Cleator G. M., Weber T., Monteyne P., Sindic C. J. M., Van Loon A. M. The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis : a consensus report. J. Neurol. Neurosurg. Psych., 1996, 61 : 339-345.
5. Corsellis J. A. N., Goldberg G. J., Norton A. R. "Limbic encephalitis" and its association with carcinoma. Brain, 1968, 91 : 481-496.
6. Dalmau J., Graus F., Rosenblum M. K., Posner J. B. Anti-Hu associated paraneoplastic encephalomyelitis/sensory neuropathy. Medicine, 1992, 71 : 59-72.
7. Dalmau J., Gultekin S. H., Volts R., Hoard R., DesChamps T., Balmaceda C., Batchelor T., Gerstner E., Eichen J., Frennier J., Posner B., Rosenfeld M. R. Mal, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders. Brain, 1999, 122 : 27-39.
8. Depré A., Sindic C. J. M., Bukasa K., Bigaignon G., Laterre C. Formes encéphalomyélitiques de l' infection à Borrelia burgdorferi. Rev. Neurol., 1988, 144 : 416-420.
9. Dropcho E. J. Neurologic paraneoplastic syndromes. J. Neurol. Sci., 1998, 153 : 264-278.
10. Fakhoury J. M., Abou-Khalil B., Kessler R. M. Limbic encephalitis and hyperactive foci on PET scan. Seizure, 1999, 8 : 427-431.
11. Gultekin S. H., Rosenfeld M. R., Voltz R., Eichen J., Posner J. B., Dalmau J. Paraneoplastic limbic encephalitis : neurological symptoms, immunological findings and tumour association in 50 patients. Brain, 2000, 123 : 1481-1494.
12. Lucchinette C. F., Kimmel D. W., Lennon V. A. Paraneoplastic and oncologic profiles of patients seropositive for type 1 antineuronal nuclear autoantibodies. Neurology, 1998, 50 : 652-657.
13. McCabe D. J. H., Burke T., Connolly S., Hutchinson M. Amnesic syndrome with bilateral mesial temporal lobe involvement in Hashimoto's encephalopathy. Neurology, 2000, 54 : 737-739.
14. Monteyne PH., Laterre E. C., Sindic C. J. M. Encephalitis in immunocompetent patients due to herpes simplex virus type 1 or 2 : determination by polymerase chain reaction and detection of intrathecal virus-specific oligoclonal antibodies. Acta Neurol. Belg., 1997a, 97 : 233-239.
15. Monteyne Ph., Albert F., Weissbrich B., Zardini E., Ciardi M., Cleator G. M., Sindic C. J. M. The detection of intrathecal synthesis of anti-herpes simplex IgG antibodies : comparison between an antigen-mediated immunoblotting technique and antibody index calculations. J. Med. Virol., 1997b, 53 : 324-331.
16. Na D. L., Hahm D. S., Park J. M., Kim S. E. Hypermetabolism of the medial temporal lobe in limbic encephalitis on 18FDG-PET Scan : a case report. Eur. Neurol., 2001, 45 : 187-189.
17. Nolte K. W., Unbehaun A., Sieker H., Kloss T. M., Paulus W. Hashimoto encephalopathy : a brain vasculitis ? Neurology, 2000, 54 : 769-770.
18. Pieret F., Sindic C. J. M., Chalon M. P., Warny M., Bolyn S., Dehaene I., Gobiet Y., Goka S., Laloux P., Monteyne Ph., Peeters A., Pierre Ph., Gillet S., Van Den Bergh P. Y. K., Wind-Hausen K., Laterre E. C. The anti-Hu syndrome : a clinical and immunological study of 7 cases. Acta Neurol. Belg., 1996, 96 : 108-116
19. Provenzale J. M., Barroriak D. P., Coleman R. E. Limbic encephalitis: Comparison of FDG PET and MR imaging findings. Am. J. Roentgenol., 1998, 170 : 1659-1660
20. 18F)fluoro-2-deoxyglucose-PET scanning in the diagnosis of paraneoplastic neurological disorders. Brain, 2001, 124 : 2223-2231
21. Shavit Y. B., Graus F., Probst A., René R., Steck A. Epilepsia partialis continua : a new manifestation of anti-HU-associated paraneoplastic encephalomyelitis. Ann. Neurol., 1999, 45 : 255-258.
22. Shaw P. J., Walls T. J., Newman P. K., Cleland P. J., Cartlidge N. E. F. Hashimoto's encephalopathy : a steroid-responsive disorder associated with high anti-thyroid titers- report of 5 cases. Neurology, 1991, 41 : 228-233.
23. Vega E, Graus F., Chen Q. M., Poisson M., Schuller E., Delattre J. Y. Intrathecal synthesis of the anti-Hu antibody in patients with paraneoplastic encephalomyelitis or sensory neuronopathy : Clinical-immunologic correlation. Neurology, 1994, 44 : 2145-3147
24. Volts R., Gultekin H., Rosenfeld M. R., Gerstner E., Eichen J., Posner B., Dalmau J. A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patient with testicular cancer. N. Engl. J. Med., 1999, 340 : 1788-1795