Up-regulation of inflammatory signalings by areca nut extract and role of Cyclooxygenase-2 -1195G>A polymorphism reveal risk of oral cancer

Cancer Research

Volumn 68, Issue 20, 2008, Pages 8489-8498

  Chiang, Shang Lun ^a   Chen, Ping Ho ^f   Lee, Chien Hung ^c   Ko, Albert Min Shan ^g   Lee, Ka Wo ^e   Lin, Ying Chu ^d   Ho, Pei Shan ^d   Tu, Hung Pin ^b   Wu, Deng Chyang ^e   Shieh, Tien Yu ^d,e   Ko, Ying Chin ^b,e,f  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b Department of Otorhinolaryngology Head and Neck Surgery   (Taiwan)

^c Department of Medical Laboratory Science and Biotechnology   (Taiwan)

^d Faculty of Dentistry   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^g UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ARECA NUT EXTRACT; ARECOLINE; BETEL EXTRACT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BETEL NUT; CANCER CELL CULTURE; CANCER PATIENT; CIGARETTE SMOKING; CYCLOOXYGENASE 2 GENE; ENZYME ACTIVATION; FIBROBLAST; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENETIC POLYMORPHISM; GENOTYPE; GINGIVA; HUMAN; HUMAN CELL; INFLAMMATION; MAJOR CLINICAL STUDY; MOUTH CANCER; MOUTH CARCINOMA; PRIORITY JOURNAL; RISK; SALIVA; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; SUBSTANCE ABUSE; UPREGULATION;

ADULT; AGED; ALCOHOL DRINKING; ARECA; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; MIDDLE AGED; MOUTH NEOPLASMS; NF-KAPPA B; PLANT EXTRACTS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RISK FACTORS; SIGNAL TRANSDUCTION; SMOKING; UP-REGULATION;

EID: 54349124402     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-0823     Document Type: Article

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