Xenobiotic-metabolizing cytochromes P450 convert prostaglandin endoperoxide to hydroxyheptadecatrienoic acid and the mutagen, malondialdehyde

Journal of Biological Chemistry

Volumn 275, Issue 16, 2000, Pages 11784-11790

  Plastaras, John P ^a   Guengerich, F Peter ^a   Nebert, Daniel W ^b   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; MALONALDEHYDE; MICROSOME ENZYME; PROSTAGLANDIN ENDOPEROXIDE; PROSTAGLANDIN SYNTHASE;

ARACHIDONIC ACID METABOLISM; ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; XENOBIOTIC METABOLISM;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CATALYSIS; CELLS, CULTURED; CHROMATOGRAPHY, THIN LAYER; CYTOCHROME P-450 ENZYME SYSTEM; FATTY ACIDS, UNSATURATED; HEME; HUMANS; MALONDIALDEHYDE; MICROSOMES, LIVER; MUTAGENS; PROSTAGLANDIN ENDOPEROXIDES; PROSTAGLANDIN H2; PROSTAGLANDINS H; RABBITS;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0034697033     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.16.11784     Document Type: Article

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