Anti-flagellin antibody responses elicited in mice orally immunized with attenuated Salmonella enterica serovar Typhimurium vaccine strains

Memorias do Instituto Oswaldo Cruz

Volumn 103, Issue 6, 2008, Pages 606-610

  Massis, L M ^a   Braga, C J M ^a   Sbrogio Almeida, M E ^b   Lauand, C ^a   Newton, S M C ^c   Klebba, P E ^c   Ferreira, L C S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Antibody response; Attenuated S. Typhimurium strains; Fagellin

Indexed keywords

MUS; SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM;

EID: 54349093801     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762008000600017     Document Type: Article

References (25)

1. Brey RN, Bixler GS, Fulginiti JP, Dilts DA, Sabara MI 1991. Oral delivery of antigens in live bacterial vectors. Adv Exp Med Biol 303: 169-184.
2. Chatfield SN, Charles IG, Makoff AJ, Oxer MD, Dougan G, Pickard D, Slater D, Fairweather NF 1992. Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine. Biotechnology (NY) 10: 888-892.
3. Cherepanov PP, Wackernagel W 1995. Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 158: 9-14.
4. Court DL, Sawitzke JA, Thomason LC 2002. Genetic engineering using homologous recombination. Annu Rev Genet 36: 361-388.
5. + T regulatory cells. J Immunol 175: 8051-8059.
6. Datsenko KA, Wanner BL 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97: 6640-6645.
7. De Almeida ME, Newton SM, Ferreira LC 1999. Antibody responses against flagellin in mice orally immunized with attenuated Salmonella vaccine strains. Arch Microbiol 172: 102-108.
8. Dougan G, Hormaeche CE, Maskell DJ 1987. Live oral Salmonella vaccines: potential use of attenuated strains as carriers of heterologous antigens to the immune system. Parasite Immunol 9: 151-160.
9. Garmory HS, Brown KA, Titball RW 2002. Salmonella vaccines for use in humans: present and future perspectives. FEMS Microbiol Rev 26: 339-353.
10. Gewirtz AT, Simon PO Jr., Schmitt CK, Taylor LJ, Hagedorn CH, O'Brien AD, Neish AS, Madara JL 2001. Salmonella typhi-murium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. J Clin Invest 107: 99-109.
11. Hoiseth SK, Stocker BA 1981. Aromatic-dependent Salmonella Typhimurium are non-virulent and effective as live vaccines. Nature 291: 238-239.
12. Honko A, Sriranganathan N, Lees CJ, Mizel SB 2006. Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis. Infect Immun 74: 1113-1120.
13. Ikeda JS, Schmitt CK, Darnell SC, Watson PR, Bispham J, Wallis TS, Weinstein DL, Metcalf ES, Adams P, O'Connor CD, O'Brien AD 2001. Flagellar phase variation of Salmonella enterica serovar Typhimurium contributes to virulence in the murine typhoid infection model but does not influence Salmonella-induced enteropathogenesis. Infect Immun 69: 3021-3030.
14. Luna MG, Martins MM, Newton SM, Costa SO, Almeida DF, Ferreira LC 1997. Cloning and expression of colonization factor antigen I (CFA/I) epitopes of enterotoxigenic Escherichia coli (ETEC) in Salmonella flagellin. Res Microbiol 148: 217-228.
15. McClelland M, Sanderson KE, Spieth J, Clifton SW, Latreille P, Courtney L, Porwollik S, Ali J, Dante M, Du F, Hou S, Layman D, Leonard S, Nguyen C, Scott K, Holmes A, Grewal N, Mulvaney E, Ryan E, Sun H, Florea L, Miller W, Stoneking T, Nhan M, Waterston R, Wilson RK 2001. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature 413: 852-856.
16. Newton SM, Jacob CO, Stocker BA 1989. Immune response to cholera toxin epitope inserted in Salmonella flagellin. Science 244: 70-72.
17. Newton SM, Kotb M, Poirier TP, Stocker BA, Beachey EH 1991. Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin. Infect Immun 59: 2158-2165.
18. Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE 2006. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog 2: e18.
19. Sanders CJ, Yu Y, Moore DA, Williams IR, Gewirtz AT 2006. Humoral immune response to flagellin requires T cells and activation of innate immunity. J Immunol 177: 2810-2818.
20. Sbrogio-Almeida ME, Ferreira LC 2001. Flagellin expressed by live Salmonella vaccine strains induces distinct antibody responses following delivery via systemic or mucosal immunization routes. FEMS Immunol Med Microbiol 30: 203-208.
21. Sbrogio-Almeida ME, Mosca T, Massis LM, Abrahamsohn IA, Ferreira LC 2004. Host and bacterial factors affecting induction of immune responses to flagellin expressed by attenuated Salmonella vaccine strains. Infect Immun 72: 2546-2555.
22. Schmieger H 1971. A method for detection of phage mutants with altered transducing ability. Mol Gen Genet 110: 378-381.
23. Stocker BA 1990. Aromatic-dependent Salmonella as live vaccine presenters of foreign epitopes as inserts in flagellin. Res Microbiol 141: 787-796.
24. Stocker BA, Newton SM 1994. Immune responses to epitopes inserted in Salmonella flagellin. Int Rev Immunol 11: 167-178.
25. Yamamoto S, Kutsukake K 2006. FljA-mediated posttranscriptional control of phase 1 flagellin expression in flagellar phase variation of Salmonella enterica serovar Typhimurium. J Bacteriol 188: 958-967.