Antibody responses against flagellin in mice orally immunized with attenuated Salmonella vaccine strains

Archives of Microbiology

Volumn 172, Issue 2, 1999, Pages 102-108

  De Almeida, Maria Elisabete Sbrogio ^a,b   Newton, Salete M ^b,d   Ferreira, Luis Carlos S ^c  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Cholera toxin; CTP3 epitope; Flagellin fusions; Mucosal vaccines; Salmonella vaccines

Indexed keywords

FLAGELLIN; SALMONELLOSIS VACCINE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; FEMALE; HOST RESISTANCE; IMMUNOGENICITY; INFECTION PREVENTION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA; SALMONELLOSIS; STRAIN DIFFERENCE;

EID: 0032780638     PISSN: 03028933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002030050746     Document Type: Article

References (26)

1. Acero-Reyes JR (1994) Insertion of cholera toxin epitopes in the Salmonella flagellin. PhD Thesis São Paulo University, São Paulo, Brazil
2. Aizpurua HJ, Russel-Jones GJ (1988) Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding. J Exp Med 167:440-45
3. Beckers W, et al. (1993) Increasing the immunogenicity of protein antigens through the genetic insertion of VQGEESNDK sequence of human IL-1b into their sequence. J Immunol 151: 1757-1764
4. Blum H, Bier H, Gross HJ (1987) Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis, 8:93-99
5. Brey RN, Bixter GS, Fulginiti JP, Dilts DA, Sabara MIJ (1991) Oral delivery of antigens in live bacterial vectors, In: Atassi MZ (ed) Immunology of proteins and peptides, vol 4. Plenum Press, ,pp 169-184
6. Brown KL, Hughes KT (1995) The role of anti-sigma factors in gene regulation. Mol Microbiol 16:397-404
7. Chen I, Pizza M, Rappuoli R, Newton SMC (1998) Effects of the insertion of a nonapeptide from murine IL-1 on the immunogenicity of carrier proteins delivered by live attenuated Salmonella. Arch Microbiol 169:113-119
8. Ciacci-Woolwine F, Blomfield IC, Richardson SH, Mizel SB (1998) Salmonella flagellin induces tumor necrosis factor alpha in a human promonocytic cell line. Infect Immun 66:1127-1134
9. Luna MG, Martins MM, Newton SMC, Costa SOP, Almeida DF, Ferreira LCS (1996) Cloning and expression of colonization factor antigen I (CFA/I) epitopes of enterotoxigenic Escherichia coli (ETEC) in Salmonella flagellin. Res Microbiol 148: 217-228
10. Macnab RM (1992) Genetics and biogenesis of bacterial flagella. Annu Rev Genet 26:131-158
11. McCormick BA, Stocker BAD, Laux DA, Cohen PS (1988) Roles of motility, chemotaxis and penetration through and growth in intestinal mucous in the ability of avirulent strain of Salmonella typhimurium to colonize the large intestine of streptomycin-treated mice. Infect Immun 56:2209-2217
12. McEwen J, Levi R, Horwitz RJ, Arnon R (1992) Synthetic recombinant vaccine expressing influenza haemagglutinin epitope in Salmonella flagellin leads to partial protection in mice. Vaccine 10:405-411
13. Mowat AM, Parrot DMV (1983) Immunological responses to fed proteins antigens in mice. Immunology 50:547-552
14. Newton SMC, Jacob CO, Stocker BAD (1989) Immune response to cholera toxin epitope inserted in Salmonella flagellin. Science 244:70-72
15. Newton SMC, Kotb M, Poirer TP, Stocker BAD, Beachey EH (1991) Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin. Infect Immun 59:2158-2165
16. Newton SMC, Joys TM, Anderson SA, Kennedy RC, Hovi ME, Stocker BAD (1995) Expression and immunogenicity of an 18-residue epitope of HIV1 gp41 inserted in the flagellar protein of a Salmonella live vaccine. Res Microbiol 146:203-216
17. Otteman KM, Miller JF (1997) Roles for motility in bacterial-host interactions. Mol Microbiol 24:1109-1117
18. Ristaino PA, Levine MM, Young CR (1983) Improved GM1-enzyme-linked immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin. J Clin Microbiol 18:808-815
19. Schmitt CK, Darnell SC, O'Brien AD (1996) The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin. J Bacteriol 178:2911-2915
20. Sthål S, Uhlén M (1997) Bacterial surface display: trends and progress. Trends Microbiol 15:185-192
21. Stocker BAD (1991) Aromatic-dependent Salmonella as live vaccine presenters of foreign epitopes as inserts in flagellin. Res Microbiol 141:757-796
22. Stocker BAD, Newton SMC (1994) Immune responses to epitopes inserted in Salmonella flagellin. Int Rev Immunol 11:167-178
23. Towbin J, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354
24. Verma NK et al. (1995a) Delivery of class I and class II MHC-restricted T-cell epitopes of listeriolysin of Listeria monocytogenes by attenuated Salmonella. Vaccine 13:142-150
25. Verma NK, Zieger HK, Stocker BAD, Scholnik GK (1995b) Induction of a cellular immune response to a defined T-cell epitope as an insert in the flagellin of a live vaccine strain of Salmonella. Vaccine 13:235-244
26. Wu JY, Newton SMC, Judd A, Stocker BAD, Robinson WS (1989) Expression of immunogenic epitopes of hepatitis B surface antigen with hybrid flagellin proteins by a vaccine strain of Salmonella. Proc Natl Acad Sci USA 86:4726-4730