메뉴 건너뛰기




Volumn 28, Issue 10, 2008, Pages 1370-1380

Expression of multidrug resistance-associated protein 1 in hepatocellular carcinoma is associated with a more aggressive tumour phenotype and may reflect a progenitor cell origin

Author keywords

ATP binding cassette transporters; Hepatic progenitor cell; Hepatocellular carcinoma; Keratin 19; Multidrug resistance; Multidrug resistance associated protein 1

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CYTOKERATIN 19; CYTOKERATIN 7; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3;

EID: 54049149978     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2008.01889.x     Document Type: Article
Times cited : (99)

References (39)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: GLOBOCAN 2000
    • Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: GLOBOCAN 2000. Int J Cancer 2001; 94: 153-6.
    • (2001) Int J Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 42149092189 scopus 로고    scopus 로고
    • Outcome of patients with hepatocellular carcinoma listed for liver transplantation within the Eurotransplant allocation system
    • Adler M, De Pauw F, Vereerstraeten P, et al. Outcome of patients with hepatocellular carcinoma listed for liver transplantation within the Eurotransplant allocation system. Liver Transpl 2008; 14: 526-33.
    • (2008) Liver Transpl , vol.14 , pp. 526-533
    • Adler, M.1    De Pauw, F.2    Vereerstraeten, P.3
  • 3
    • 0036096420 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Diagnosis and treatment
    • Befeler AS, Di Bisceglie AM. Hepatocellular carcinoma: Diagnosis and treatment. Gastroenterology 2002; 122: 1609-19.
    • (2002) , vol.122 , pp. 1609-1619
    • Befeler, A.S.1    Di Bisceglie, A.M.2
  • 4
    • 0032742183 scopus 로고    scopus 로고
    • Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: Resection versus transplantation
    • Llovet JM, Fuster J, Bruix J. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: Resection versus transplantation. Hepatology 1999; 30: 1434-40.
    • (1999) Hepatology , vol.30 , pp. 1434-1440
    • Llovet, J.M.1    Fuster, J.2    Bruix, J.3
  • 5
    • 0036799144 scopus 로고    scopus 로고
    • Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: Review of the randomised clinical trials
    • Schwartz JD, Schwartz M, Mandeli J, Sung M. Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: Review of the randomised clinical trials. Lancet Oncol 2002; 3: 593-603.
    • (2002) Lancet Oncol , vol.3 , pp. 593-603
    • Schwartz, J.D.1    Schwartz, M.2    Mandeli, J.3    Sung, M.4
  • 6
    • 0347755373 scopus 로고    scopus 로고
    • Multidrug resistance in cancer chemotherapy and xenobiotic protection mediated by the half ATP-binding cassette transporter ABCG2
    • Han B, Zhang JT. Multidrug resistance in cancer chemotherapy and xenobiotic protection mediated by the half ATP-binding cassette transporter ABCG2. Curr Med Chem Anticancer Agents 2004; 4: 31-42.
    • (2004) Curr Med Chem Anticancer Agents , vol.4 , pp. 31-42
    • Han, B.1    Zhang, J.T.2
  • 7
    • 0041833334 scopus 로고    scopus 로고
    • ABC-transporters: Implications on drug resistance from microorganisms to human cancers
    • Lage H. ABC-transporters: Implications on drug resistance from microorganisms to human cancers. Int J Antimicrob Agents 2003; 22: 188-99.
    • (2003) Int J Antimicrob Agents , vol.22 , pp. 188-199
    • Lage, H.1
  • 8
    • 0026687242 scopus 로고
    • P-glycoprotein expression during tumor progression in the rat-liver
    • Bradley G, Sharma R, Rajalakshmi S, Ling V. P-glycoprotein expression during tumor progression in the rat-liver. Cancer Res 1992; 52: 5154-61.
    • (1992) Cancer Res , vol.52 , pp. 5154-5161
    • Bradley, G.1    Sharma, R.2    Rajalakshmi, S.3    Ling, V.4
  • 9
    • 0034800024 scopus 로고    scopus 로고
    • Multidrug resistance gene (MDR-1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection
    • Kato A, Miyazaki M, Ambiru S, et al. Multidrug resistance gene (MDR-1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection. J Surg Oncol 2001; 78: 110-5.
    • (2001) J Surg Oncol , vol.78 , pp. 110-115
    • Kato, A.1    Miyazaki, M.2    Ambiru, S.3
  • 10
    • 0034100195 scopus 로고    scopus 로고
    • Expression of P-glycoprotein in hepatocellular carcinoma - A determinant of chemotherapy response
    • Ng IOL, Liu CL, Fan ST, Ng M. Expression of P-glycoprotein in hepatocellular carcinoma - a determinant of chemotherapy response. Am J Clin Pathol 2000; 113: 355-63.
    • (2000) Am J Clin Pathol , vol.113 , pp. 355-363
    • Ng, I.O.L.1    Liu, C.L.2    Fan, S.T.3    Ng, M.4
  • 11
    • 0025013836 scopus 로고
    • Doxorubicin for unresectable hepatocellular-carcinoma - A prospective-study on the addition of verapamil
    • Lai ECS, Choi TK, Cheng CH, et al. Doxorubicin for unresectable hepatocellular-carcinoma - a prospective-study on the addition of verapamil. Cancer 1990; 66: 1685-7.
    • (1990) Cancer , vol.66 , pp. 1685-1687
    • Lai, E.C.S.1    Choi, T.K.2    Cheng, C.H.3
  • 12
    • 0036845842 scopus 로고    scopus 로고
    • Expression of P-glycoprotein and C-MOAT in human hepatocellular carcinoma - Detection by immunostaining
    • Richart J, Brunt EM, Di Bisceglie AM. Expression of P-glycoprotein and C-MOAT in human hepatocellular carcinoma - detection by immunostaining. Dig Dis Sci 2002; 47: 2454-8.
    • (2002) Dig Dis Sci , vol.47 , pp. 2454-2458
    • Richart, J.1    Brunt, E.M.2    Di Bisceglie, A.M.3
  • 13
    • 0030975241 scopus 로고    scopus 로고
    • Inverse relationship between P-glycoprotein expression and its proliferative activity in hepatocellular carcinoma
    • Takanishi K, Miyazaki M, Ohtsuka M, Nakajima N. Inverse relationship between P-glycoprotein expression and its proliferative activity in hepatocellular carcinoma. Oncology 1997; 54: 231-7.
    • (1997) Oncology , vol.54 , pp. 231-237
    • Takanishi, K.1    Miyazaki, M.2    Ohtsuka, M.3    Nakajima, N.4
  • 14
    • 29744470059 scopus 로고    scopus 로고
    • Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver
    • Vander Borght S, Libbrecht L, Blokzijl H, et al. Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver. J Pathol 2005; 207: 471-82.
    • (2005) J Pathol , vol.207 , pp. 471-482
    • Vander Borght, S.1    Libbrecht, L.2    Blokzijl, H.3
  • 15
    • 17044400593 scopus 로고    scopus 로고
    • Hepatobiliary transporter expression in human hepatocellular carcinoma
    • Zollner G, Wagner M, Fickert P, et al. Hepatobiliary transporter expression in human hepatocellular carcinoma. Liver Int 2005; 25: 367-79.
    • (2005) Liver Int , vol.25 , pp. 367-379
    • Zollner, G.1    Wagner, M.2    Fickert, P.3
  • 16
    • 0041522442 scopus 로고    scopus 로고
    • High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease
    • Ros JE, Libbrecht L, Geuken M, et al. High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease. J Pathol 2003; 200: 553-60.
    • (2003) J Pathol , vol.200 , pp. 553-560
    • Ros, J.E.1    Libbrecht, L.2    Geuken, M.3
  • 17
    • 0038121803 scopus 로고    scopus 로고
    • ATP binding cassette transporter gene expression in rat liver progenitor cells
    • Ros JE, Roskams TAD, Geuken M, et al. ATP binding cassette transporter gene expression in rat liver progenitor cells. Gut 2003; 52: 1060-7.
    • (2003) Gut , vol.52 , pp. 1060-1067
    • Ros, J.E.1    Roskams, T.A.D.2    Geuken, M.3
  • 18
    • 33748066311 scopus 로고    scopus 로고
    • Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: Possible functional consequences
    • Vander Borght S, Libbrecht L, Katoonizadeh A, et al. Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/ reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: Possible functional consequences. J Histochem Cytochem 2006; 54: 1051-9.
    • (2006) J Histochem Cytochem , vol.54 , pp. 1051-1059
    • Vander Borght, S.1    Libbrecht, L.2    Katoonizadeh, A.3
  • 19
    • 33645742425 scopus 로고    scopus 로고
    • A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
    • Lee JS, Heo J, Libbrecht L, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006; 12: 410-6.
    • (2006) Nat Med , vol.12 , pp. 410-416
    • Lee, J.S.1    Heo, J.2    Libbrecht, L.3
  • 20
    • 0031757473 scopus 로고    scopus 로고
    • Primary liver tumour of intermediate (hepatocyte bile duct cell) phenotyp: A progenitor cell tumour?
    • Robrechts C, De Vos R, Van den Heuvel M, et al. Primary liver tumour of intermediate (hepatocyte bile duct cell) phenotyp: A progenitor cell tumour? Liver 1998; 18: 288-93.
    • (1998) Liver , vol.18 , pp. 288-293
    • Robrechts, C.1    De Vos, R.2    Van den Heuvel, M.3
  • 21
    • 33745533559 scopus 로고    scopus 로고
    • Liver stem cells and their implication in hepatocellular and cholangiocarcinoma
    • Roskams T. Liver stem cells and their implication in hepatocellular and cholangiocarcinoma. Oncogene 2006; 25: 3818-22.
    • (2006) Oncogene , vol.25 , pp. 3818-3822
    • Roskams, T.1
  • 22
    • 4544273428 scopus 로고    scopus 로고
    • Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
    • Lee JS, Chu IS, Heo J, et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 2004; 40: 667-76.
    • (2004) Hepatology , vol.40 , pp. 667-676
    • Lee, J.S.1    Chu, I.S.2    Heo, J.3
  • 23
    • 33645551138 scopus 로고    scopus 로고
    • The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin
    • Durnez A, Verslype C, Nevens F, et al. The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin. Histopathology 2006; 49: 138-51.
    • (2006) Histopathology , vol.49 , pp. 138-151
    • Durnez, A.1    Verslype, C.2    Nevens, F.3
  • 24
    • 0242609884 scopus 로고    scopus 로고
    • Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence
    • Uenishi T, Kubo S, Yamamoto T, et al. Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence. Cancer Sci 2003; 94: 851-7.
    • (2003) Cancer Sci , vol.94 , pp. 851-857
    • Uenishi, T.1    Kubo, S.2    Yamamoto, T.3
  • 25
    • 0023894776 scopus 로고
    • Cytokeratin expression in hepatocellular-carcinoma - An immunohistochemical study
    • Vaneyken P, Sciot R, Paterson A, et al. Cytokeratin expression in hepatocellular-carcinoma - an immunohistochemical study. Human Pathol 1988; 19: 562-8.
    • (1988) Human Pathol , vol.19 , pp. 562-568
    • Vaneyken, P.1    Sciot, R.2    Paterson, A.3
  • 26
    • 0029794269 scopus 로고    scopus 로고
    • Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers - Clinical and biological implications
    • Wu PC, Fang JWS, Lau VKT, et al. Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers - clinical and biological implications. Am J Pathol 1996; 149: 1167-75.
    • (1996) Am J Pathol , vol.149 , pp. 1167-1175
    • Wu, P.C.1    Fang, J.W.S.2    Lau, V.K.T.3
  • 27
    • 34247642682 scopus 로고    scopus 로고
    • Histologic characteristics and prognostic significance in small hepatocellular carcinoma with biliary differentiation - Subdivision and comparison with ordinary hepatocellular carcinoma
    • Aishima S, Nishihara Y, Kuroda Y, et al. Histologic characteristics and prognostic significance in small hepatocellular carcinoma with biliary differentiation - subdivision and comparison with ordinary hepatocellular carcinoma. Am J Surg Pathol 2007; 31: 783-91.
    • (2007) Am J Surg Pathol , vol.31 , pp. 783-791
    • Aishima, S.1    Nishihara, Y.2    Kuroda, Y.3
  • 28
    • 0031058993 scopus 로고    scopus 로고
    • Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
    • Roelofsen H, Vos TA, Schippers IJ, et al. Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells. Gastroenterology 1997; 112: 511-21.
    • (1997) Gastroenterology , vol.112 , pp. 511-521
    • Roelofsen, H.1    Vos, T.A.2    Schippers, I.J.3
  • 29
    • 78651053628 scopus 로고
    • Primary carcinoma of the liver: A study of 100 cases among 48,900 necropsies
    • Edmondson HA, Steiner PE. Primary carcinoma of the liver: A study of 100 cases among 48,900 necropsies. Cancer 1954; 7: 462-503.
    • (1954) Cancer , vol.7 , pp. 462-503
    • Edmondson, H.A.1    Steiner, P.E.2
  • 30
    • 0026447566 scopus 로고
    • Occurrence of oval-type cells in hepatitis-B virus-associated human hepatocarcinogenesis
    • Hsia CC, Evarts RP, Nakatsukasa H, et al. Occurrence of oval-type cells in hepatitis-B virus-associated human hepatocarcinogenesis. Hepatology 1992; 16: 1327-33.
    • (1992) Hepatology , vol.16 , pp. 1327-1333
    • Hsia, C.C.1    Evarts, R.P.2    Nakatsukasa, H.3
  • 31
    • 1642532389 scopus 로고    scopus 로고
    • Primary liver carcinoma of intermediate (hepatocyte-cholangiocyte) phenotype
    • Kim H, Park C, Han KH, et al. Primary liver carcinoma of intermediate (hepatocyte-cholangiocyte) phenotype. J Hepatol 2004; 40: 298-304.
    • (2004) J Hepatol , vol.40 , pp. 298-304
    • Kim, H.1    Park, C.2    Han, K.H.3
  • 32
    • 0035889601 scopus 로고    scopus 로고
    • Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma
    • Nies AT, Konig J, Pfannschmidt M, et al. Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma. Int J Cancer 2001; 94: 492-9.
    • (2001) Int J Cancer , vol.94 , pp. 492-499
    • Nies, A.T.1    Konig, J.2    Pfannschmidt, M.3
  • 33
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • Leslie EM, Deeley RG, Cole SPC. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology 2001; 167: 3-23.
    • (2001) Toxicology , vol.167 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.C.3
  • 34
    • 0035793239 scopus 로고    scopus 로고
    • Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood
    • Laupeze B, Amiot L, Payen L, et al. Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood. Life Sci 2001; 68: 1323-31.
    • (2001) Life Sci , vol.68 , pp. 1323-1331
    • Laupeze, B.1    Amiot, L.2    Payen, L.3
  • 36
    • 35649013187 scopus 로고    scopus 로고
    • Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation
    • Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. J Biol Chem 2007; 282: 30452-65.
    • (2007) J Biol Chem , vol.282 , pp. 30452-30465
    • Franco, R.1    Panayiotidis, M.I.2    Cidlowski, J.A.3
  • 37
    • 34347230130 scopus 로고    scopus 로고
    • Glutathione export during apoptosis requires functional multidrug resistance-associated proteins
    • Hammond CL, Marchan R, Krance SM, Ballatori N. Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. J Biol Chem 2007; 282: 14337-47.
    • (2007) J Biol Chem , vol.282 , pp. 14337-14347
    • Hammond, C.L.1    Marchan, R.2    Krance, S.M.3    Ballatori, N.4
  • 38
    • 21044442673 scopus 로고    scopus 로고
    • Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: Prognostic implications
    • Berger W, Setinek U, Hollaus P, et al. Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: Prognostic implications. J Cancer Res Clin Oncol 2005; 131: 355-63.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 355-363
    • Berger, W.1    Setinek, U.2    Hollaus, P.3
  • 39
    • 20044364737 scopus 로고    scopus 로고
    • Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: The Austrian breast and colorectal cancer study group
    • Filipits M, Pohl G, Rudas M, et al. Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: The Austrian breast and colorectal cancer study group. J Clin Oncol 2005; 23: 1161-8.
    • (2005) J Clin Oncol , vol.23 , pp. 1161-1168
    • Filipits, M.1    Pohl, G.2    Rudas, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.