Angiogenic activation of valvular endothelial cells in aortic valve stenosis

Experimental Cell Research

Volumn 298, Issue 2, 2004, Pages 455-464

  Chalajour, Fariba ^a   Treede, Hendrik ^a   Ebrahimnejad, Alireza ^a   Lauke, Heidrun ^a   Reichenspurner, Hermann ^a   Ergun, Suleyman ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Angiogenesis; Aortic valve; CEACAM1; Endostatin; Endothelial tube formation

Indexed keywords

ANGIOPOIETIN RECEPTOR; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CD31 ANTIGEN; CD34 ANTIGEN; COLLAGEN GEL; ENDOSTATIN; VON WILLEBRAND FACTOR;

AGED; ANGIOGENESIS; AORTA VALVE; AORTA VALVE STENOSIS; ARTICLE; BASEMENT MEMBRANE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; EX VIVO STUDY; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; MALE; NEOVASCULARIZATION (PATHOLOGY); PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPROUT; WEIBEL PALADE BODY; WESTERN BLOTTING;

EID: 3242665123     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.04.034     Document Type: Article

References (35)

1. Drolet M.C., Arsenault M., Couet J. Experimental aortic valve stenosis in rabbits. J. Am. Coll. Cardiol. 41:2003;1211-1217
2. Schoen F.J., Levy R.J. Founder's Award, 25th Annual Meeting of the Society for Biomaterials, perspectives. Providence, RI, April 28-May 2, 1999. Tissue heart valves: current challenges and future research perspectives. J. Biomed. Mater. Res. 47:1999;439-465
3. Paranya G., Vineberg S., Dvorin E., Kaushal S., Roth S.J., Rabkin E., Schoen F.J., Bischoff J. Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Am. J. Pathol. 159:2001;1335-1343
4. Ghaisas N.K., Foley J.B., O'Briain D.S., Crean P., Kelleher D., Walsh M. Adhesion molecules in nonrheumatic aortic valve disease: endothelial expression, serum levels and effects of valve replacement. J. Am. Coll. Cardiol. 36:2000;2257-2262
5. Hammon J.W. Jr., O'Sullivan M.J., Oury J., Fosburg R.G. Allograft cardiac valves. A view through the scanning electron microscope. J. Thorac. Cardiovasc. Surg. 68:1974;352-360
6. Soini Y., Salo T., Satta J. Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis. Hum. Pathol. 34:2003;756-763
7. Moulton K.S., Heller E., Konerding M.A., Flynn E., Palinski W., Folkman J. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation. 99:1999;1726-1732
8. Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 86:1996;353-364
9. Dejana E. Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis. J. Clin. Invest. 98:1996;1949-1953
10. Obrink B. C-CAM (cell-CAM 105)-a member of the growing immunoglobulin superfamily of cell adhesion proteins. BioEssays. 13:1991;227-234
11. Ergun S., Kilic N., Ziegeler G., Hansen A., Nollau P., Gotze J., Wurmbach J.H., Horst A., Weil J., Fernando M., Wagener C. CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor. Mol. Cell. 5:2000;311-320
12. Gehling U.M., Ergun S., Schumacher U., Wagener C., Pantel K., Otte M., Schuch G., Schafhausen P., Mende T., Kilic N., Kluge K., Schafer B., Hossfeld D.K., Fiedler W. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. [In Process Citation] Blood. 95:2000;3106-3112
13. Wen W., Moses M.A., Wiederschain D., Arbiser J.L., Folkman J. The generation of endostatin is mediated by elastase. Cancer Res. 59:1999;6052-6056
14. Felbor U., Dreier L., Bryant R.A., Ploegh H.L., Olsen B.R., Mothes W. Secreted cathepsin L generates endostatin from collagen XVIII. EMBO J. 19:2000;1187-1194
15. O'Reilly M.S., Boehm T., Shing Y., Fukai N., Vasios G., Lane W.S., Flynn E., Birkhead J.R., Olsen B.R., Folkman J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell. 88:1997;277-285
16. Ergun S., Kilic N., Wurmbach J.-H., Ebrahimnejad A., Fernando M., Sevinc S., Kilic E., Chalajour F., Lauke H., Lamszus K., Hammerer P., Weil J., Herbst H., Folkman J. Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes. Angiogenesis. 4:2001;193-206
17. Dixelius J., Cross M., Matsumoto T., Sasaki T., Timpl R., Claesson-Welsh L. Endostatin regulates endothelial cell adhesion and cytoskeletal organization. Cancer Res. 62:2002;1944-1947
18. Ergun S., Kilic N., Fiedler W., Mukhopadhyay A.K. Vascular endothelial growth factor and its receptors in normal human testicular tissue. Mol. Cell. Endocrinol. 131:1997;9-20
19. Pepper M.S., Ferrara N., Orci L., Montesano R. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem. Biophys. Res. Commun. 189:1992;824-831
20. Kilic N., Ergun S. Methods to evaluate the formation and stabilization of blood vessels and their role in tumor growth and metastasis. Brooks S.A., Schumacher U. Metastasis Research Protocols. 2001;125-148 Humana Press, Oxford
21. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685
22. Constantinescu E., Alexandru D., Alexandru V. An ex vivo model to study the monocyte-endothelial cell interaction in the prelesional stage of experimentally-induced atherogenesis in hamster. J. Submicrosc. Cytol. Pathol. 34:2002;115-124
23. Lee Y.S., Chou Y.Y. Endothelial alterations and senile calcific aortic stenosis: an electron microscopic observation. Proc. Natl. Sci. Counc., Repub. China, Part B. 21:1997;137-143
24. Riddle J.M., Magilligan D.J. Jr., Stein P.D. Surface topography of stenotic aortic valves by scanning electron microscopy. Circulation. 61:1980;496-502
25. Tropea B.I., Huie P., Cooke J.P., Tsao P.S., Sibley R.K., Zarins C.K. Hypertension-enhanced monocyte adhesion in experimental atherosclerosis. J. Vasc. Surg. 23:1996;596-605
26. Bahlmann F.H., De Groot K., Spandau J.M., Landry A.L., Hertel B., Duckert T., Boehm S.M., Menne J., Haller H., Fliser D. Erythropoietin regulates endothelial progenitor cells. Blood. 103:2004;921-926
27. Salven P., Mustjoki S., Alitalo R., Alitalo K., Rafii S. VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells. Blood. 101:2003;168-172
28. Kalka C., Masuda H., Takahashi T., Gordon R., Tepper O., Gravereaux E., Pieczek A., Iwaguro H., Hayashi S.I., Isner J.M., Asahara T. Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects. Circ. Res. 86:2000;1198-1202
29. Gomez-Navarro J., Contreras J.L., Arafat W., Jiang X.L., Krisky D., Oligino T., Marconi P., Hubbard B., Glorioso J.C., Curiel D.T., Thomas J.M. Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. Gene Ther. 7:2000;43-52
30. Peichev M., Naiyer A.J., Pereira D., Zhu Z., Lane W.J., Williams M., Oz M.C., Hicklin D.J., Witte L., Moore M.A., Rafii S. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 95:2000;952-958
31. Schmeisser A., Strasser R.H. Phenotypic overlap between hematopoietic cells with suggested angioblastic potential and vascular endothelial cells. J. Hematother. Stem Cell Res. 11:2002;69-79
32. Muller A.M., Cronen C., Kupferwasser L.I., Oelert H., Muller K.M., Kirkpatrick C.J. Expression of endothelial cell adhesion molecules on heart valves: up-regulation in degeneration as well as acute endocarditis. J. Pathol. 191:2000;54-60
33. Bischoff J., Brasel C., Kraling B., Vranovska K. E-selectin is upregulated in proliferating endothelial cells in vitro. Microcirculation. 4:1997;279-287
34. Koch A.E., Halloran M.M., Haskell C.J., Shah M.R., Polverini P.J. Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1. Nature. 376:1995;517-519
35. Kraling B.M., Razon M.J., Boon L.M., Zurakowski D., Seachord C., Darveau R.P., Mulliken J.B., Corless C.L., Bischoff J. E-selectin is present in proliferating endothelial cells in human hemangiomas. Am. J. Pathol. 148:1996;1181-1191