The tetraspanin CD63 is involved in granule targeting of neutrophil elastase

Blood

Volumn 112, Issue 8, 2008, Pages 3444-3454

  Källquist, Linda ^a   Hansson, Markus ^a,d   Persson, Ann Maj ^a   Janssen, Hans ^b   Calafat, Jero ^b   Tapper, Hans ^c   Olsson, Inge ^a  

^a LUND UNIVERSITY   (Sweden)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c LUND UNIVERSITY   (Sweden)

^d BMC C14   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD63 ANTIGEN; LEUKOCYTE ELASTASE; MYELOPEROXIDASE; SMALL INTERFERING RNA; TETRASPANIN; FIBRINOGEN RECEPTOR; LEUKOCYTE ANTIGEN; LYSOSOMAL PROTEIN GP53; PEROXIDASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; GRANULE CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LEUKEMIA CELL; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; ANIMAL; BIOLOGICAL MODEL; CELL GRANULE; CELL STRAIN COS1; CELL STRAIN HL 60; CERCOPITHECUS; GOLGI COMPLEX; METABOLISM; NEUTROPHIL; PHYSIOLOGY; PLASMID;

ANIMALS; ANTIGENS, CD; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOPLASM; CYTOPLASMIC GRANULES; GOLGI APPARATUS; HL-60 CELLS; HUMANS; LEUKOCYTE ELASTASE; MODELS, BIOLOGICAL; NEUTROPHILS; PEROXIDASE; PLASMIDS; PLATELET MEMBRANE GLYCOPROTEINS; RNA INTERFERENCE;

EID: 54049113079     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-10-116285     Document Type: Article

References (41)

1. Dell'Angelica EC, Mullins C, Caplan S. Bonifacino JS. Lysosome-related organelles. FASEB J. 2000;14:1265-1278.
2. Blott EJ, Griffiths GM. Secretory lysosomes. Nat Rev Mol Cell Biol. 2002;3:122-131.
3. Borregaard N, Gowland JB. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood. 1997;89:3503-3521.
4. Gullberg U, Bengtsson N, Bulow E, Garwicz D, Lindmark A, Olsson I. Processing and targeting of granule proteins in human neutrophils. J Immunol Methods. 1999;232:201-210.
5. Belaaouaj A, Kim KS, Shapiro SD. Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science. 2000;289: 1185-1188.
6. Tkalcevic J, Novelli M, Phylactides M, Iredale JP, Segal AW, Roes J. Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G. Immunity. 2000;12:201-210.
7. Gullberg U, Lindmark A, Lindgren G, Persson AM. Nilsson E. Olsson I. Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL. J Biol Chem. 1995;270: 12912-12918.
8. Salvesen G, Enghild JJ. Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases. Biomed Biochim Acta. 1991; 50:665-671.
9. Kornfeld S, Mellman I. The biogenesis of lysosomes. Annu Rev Cell Biol. 1989;5:483-525.
10. Griffiths GM, Isaaz S. Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor. J Cell Biol. 1993;120:885-896.
11. Glickman JN, Kornfeld S. Mannose 6-phosphateindependent targeting of lysosomal enzymes in l-cell disease B lymphoblasts. J Cell Biol. 1993; 123:99-108.
12. Neufeld EF, Lim TW, Shapiro LJ. Inherited disorders of lysosomal metabolism. Annu Rev Biochem. 1975;44:357-376.
13. Simpson F, Peden AA, Christopoulou L, Robinson MS. Characterization of the adaptor-related protein complex, AP-3. J Cell Biol. 1997;137:835-845.
14. Peden AA, Oorschot V, Hesser BA, Austin CD, Scheller RH, Klumperman J. Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol. 2004;164:1065-1076.
15. Benson KF, Li FQ, Person RE, et al. Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase. Nat Genet. 2003;35:90-96.
16. Fontana S, Parolini S, Vermi W, et al. Innate immunity defects in Hermansky-Pudlak type 2 syndrome. Blood. 2006;107:4857-4864.
17. Dahlgren C, Carlsson SR, Karlsson A, Lundqvist H, Sjolin C. The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils. Biochem J. 1995; 311(pt2):667-674.
18. Cieutat AM, Lobel P, August JT, et al. Azurophilic granules of human neutrophilic leukocytes are deficient in lysosome-associated membrane proteins but retain the mannose 6-phosphate recognition marker. Blood. 1998;91:1044-1058.
19. Tapper H, Kallquist L, Johnsson E, Persson AM, Hansson M, Olsson I. Neutrophil elastase sorting involves plasma membrane trafficking requiring the C-terminal propeptide. Exp Cell Res. 2006; 312:3471-3484. 20. Cham BP, Gerrard JM, Bainton DF. Granulophysin is located in the membrane of azurophilic granules in human neutrophils and mobilizes to the plasma membrane following cell stimulation. Am J Pathol. 1994;144:1369-1380.
20. Rous BA, Reaves BJ, Ihrke G, et al. Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes. Mol Biol Cell. 2002; 13:1071-1082.
21. Olsson I, Olofsson T, Odeberg H. Myeloperoxidase-mediated iodination in granulocytes. Scand J Haematol. 1972;9:483-491.
22. Takino T, Miyamori H, Kawaguchi N, Uekita T, Seiki M, Sato H. Tetraspanin CD63 promotes targeting and lysosomal proteolysis of membranetype 1 matrix metalloproteinase. Biochem Biophys Res Commun. 2003;304:160-166.
23. Codina J, Li J, Dubose TD Jr. CD63 interacts with the carboxy terminus of the colonic H+-K+-ATPase to increase plasma membrane localization and 86Rb+ uptake. Am J Physiol Cell Physiol. 2005;288:C1279-C1286.
24. Duffield A, Kamsteeg EJ, Brown AN, Pagel P, Caplan MJ. The tetraspanin CD63 enhances the internalization of the H, K-ATPase beta-subunit. Proc Natl Acad Sci U S A. 2003;100:15560-15565.
25. Gao Y, Rosen H, Johnsson E, Calafat J, Tapper H, Olsson I. Sorting of soluble TNF-receptor for granule storage in hematopoietic cells as a principle for targeting of selected proteins to inflamed sites. Blood. 2003;102:682-688.
26. Gao Y, Hansson M, Calafat J, Tapper H, Olsson I. Sorting soluble tumor necrosis factor (TNF) receptor for storage and regulated secretion in hematopoietic cells. J Leukoc Biol. 2004;76:876-885.
27. Calafat J, Janssen H, Stahle-Backdahl M, ZuurbierAE, Knol EF, Egesten A. Human monocytes and neutrophils store transforming growth factoralpha in a subpopulation of cytoplasmic granules. Blood. 1997;90:1255-1266.
28. Kovalenko OV, Yang X, Kolesnikova TV, Hemler ME. Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking. Biochem J. 2004;377:407-417.
29. Kovalenko OV, Metcalf DG, DeGrado WF Hemler ME. Structural organization and interactions of transmembrane domains in tetraspanin proteins. BMC Struct Biol (http://www.biomedcentral.com/1472-6807/5/11). 2005;5:11.
30. Niemann CU, Abrink M, Pejler G, et al. Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood. 2007;109:4478-4486.
31. Lemansky P, Smolenova E, Wrocklage C, Hasilik A. Neutrophil elastase is associated with serglycin on its way to lysosomes in U937 cells. Cell Immunol. 2007;246:1-7.
32. Hansson M, Olsson I, Nauseef WM. Biosynthesis, processing, and sorting of human myeloperoxidase. Arch Biochem Biophys. 2006;445:214-224.
33. Collins SJ. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood. 1987;70:1233-1244.
34. Mantegazza AR, Barrio MM, Moutel S, et al. CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells. Blood. 2004;104:1183-1190.
35. Maecker HT, Todd SC, Levy S. The tetraspanin superfamily: molecular facilitators. FASEB J. 1997;11:428-442.
36. Levy S, Shoham T. The tetraspanin web modulates immune-signalling complexes. Nat Rev Immunol. 2005:5:136-148.
37. Jung KK, Liu XW, Chirco R, Fridman R, Kim HR. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J. 2006;25:3934-3942.
38. Olsson I. Chondroitin sulfate proteolycan of human leukocytes. Biochim Biophys Acta. 1969; 177:241-249.
39. Olsson I. The intracellular transport of glycosaminoglycans (mucopolysaccharides) in human leukocytes. Exp Cell Res. 1969;54:318-325.
40. Horwitz MS, Duan Z, Korkmaz B, Lee HH, Mealiffe ME, Salipante SJ. Neutrophil elastase in cyclic and severe congenital neutropenia. Blood. 2007;109:1817-1824.
41. Reczek D, Schwake M, Schroder J, et al. LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase. Cell. 2007;131:770-783.