Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase

Nature Genetics

Volumn 35, Issue 1, 2003, Pages 90-96

  Benson, Kathleen F ^a   Li, Feng Qian ^a   Person, Richard E ^a   Albani, Dalila ^a,d   Duan, Zhijun ^a   Wechsler, Jeremy ^a,e   Meade White, Kimberly ^a,f   Williams, Kayleen ^a   Acland, Gregory M ^b   Niemeyer, Glenn ^c   Lothrop, Clinton D ^c   Horwitz, Marshall ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c AUBURN UNIVERSITY   (United States)

^d Cabinet Beau de Loménie   (France)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; LEUKOCYTE ELASTASE; MEMBRANE PROTEIN;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CARBOXY TERMINAL SEQUENCE; DNA FLANKING REGION; DOG; ENZYME ACTIVITY; GENE DISRUPTION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GOLGI COMPLEX; HEMATOPOIESIS; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROCESSING;

ADAPTOR PROTEIN COMPLEX 3; ANIMALS; CELL MEMBRANE; DOG DISEASES; DOGS; HEMATOPOIESIS; HUMANS; LEUKOCYTE ELASTASE; MOLECULAR SEQUENCE DATA; MUTATION; NEUTROPENIA; NEUTROPHILS; PEDIGREE; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT;

ANIMALIA; CANIS FAMILIARIS; UNIDENTIFIED AGENTS;

EID: 0041353534     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1224     Document Type: Article

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