Tetraspanin CD63 promotes targeting and lysosomal proteolysis of membrane-type 1 matrix metalloproteinase

Biochemical and Biophysical Research Communications

Volumn 304, Issue 1, 2003, Pages 160-166

  Takino, Takahisa ^a   Miyamori, Hisashi ^a   Kawaguchi, Noriko ^a   Uekita, Takamasa ^b   Seiki, Motoharu ^b   Sato, Hiroshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

CD63; Internalization; Lysosomes; MMP; MT1 MMP; Proteolysis; Tetraspanins

Indexed keywords

CD63 ANTIGEN; CHLOROQUINE; HEMOPEXIN; MATRIX METALLOPROTEINASE 14; PROTEINASE INHIBITOR; TETRASPANIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; LYSOSOME; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TRANSPORT;

EID: 0037466459     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00544-8     Document Type: Article

References (21)

1. Sato H., Takino T., Okada Y., Cao J., Shinagawa A., Yamamoto E., Seiki M. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature. 370:1994;61-65.
2. Takino T., Sato H., Yamamoto E., Seiki M. Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain. Gene. 155:1995;293-298.
3. Takino T., Sato H., Shinagawa A., Seiki M. Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J. Biol. Chem. 270:1995;23013-23020.
4. Pei D. Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. J. Biol. Chem. 274:1999;8925-8932.
5. Seiki M. Membrane-type matrix metalloproteinases. APMIS. 107:1999;137-143.
6. Tsunezuka Y., Kinoh H., Takino T., Watanabe Y., Okada Y., Shinagawa A., Sato H., Seiki M. Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay. Cancer Res. 56:1996;5678-5683.
7. Yana I., Weiss S.J. Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases. Mol. Biol. Cell. 11:2000;2387-2401.
8. Lehti K., Lohi J., Valtanen H., Keski-Oja J. Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface. Biochem. J. 334(Part 2):1998;345-353.
9. Jiang A., Lehti K., Wang X., Weiss S.J., Keski-Oja J., Pei D. Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis. Proc. Natl. Acad. Sci. USA. 98:2001;13693-13698.
10. Uekita T., Itoh Y., Yana I., Ohno H., Seiki M. Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity. J. Cell Biol. 155:2001;1345-1356.
11. Berditchevski F. Complexes of tetraspanins with integrins: more than meets the eye. J. Cell Sci. 114:2001;4143-4151.
12. Fukuda M. Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking. J. Biol. Chem. 266:1991;21327-21330.
13. Hotta H., Ross A.H., Huebner K., Isobe M., Wendeborn S., Chao M.V., Ricciardi R.P., Tsujimoto Y., Croce C.M., Koprowski H. Molecular cloning and characterization of an antigen associated with early stages of melanoma tumor progression. Cancer Res. 48:1988;2955-2962.
14. Kondoh M., Ueda M., Ichihashi M., Mishima Y. Decreased expression of human melanoma-associated antigen ME491 along the progression of melanoma pre-canceroses to invasive and metastatic melanomas. Melanoma Res. 3:1993;241-245.
15. Radford K.J., Mallesch J., Hersey P. Suppression of human melanoma cell growth and metastasis by the melanoma-associated antigen CD63 (ME491). Int. J. Cancer. 62:1995;631-635.
16. Kinoshita T., Sato H., Okada A., Ohuchi E., Imai K., Okada Y., Seiki M. TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J. Biol. Chem. 273:1998;16098-16103.
17. Dell'Angelica E.C., Shotelersuk V., Aguilar R.C., Gahl W.A., Bonifacino J.S. Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor. Mol. Cell. 3:1999;11-21.
18. Kobayashi T., Vischer U.M., Rosnoblet C., Lebrand C., Lindsay M., Parton R.G., Kruithof E.K., Gruenberg J. The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. Mol. Biol. Cell. 11:2000;1829-1843.
19. Berditchevski F., Tolias K.F., Wong K., Carpenter C.L., Hemler M.E. A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase. J. Biol. Chem. 272:1997;2595-2598.
20. Mori H., Tomari T., Koshikawa N., Kajita M., Itoh Y., Sato H., Tojo H., Yana I., Seiki M. CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain. EMBO J. 21:2002;3949-3959.
21. Miyamori H., Takino T., Kobayashi Y., Tokai H., Itoh Y., Seiki M., Sato H. Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases. J. Biol. Chem. 276:2001;28204-28211.