Dynamic of hyperglycemia as a predictor of stroke outcome in the ECASS-II trial

Stroke

Volumn 39, Issue 10, 2008, Pages 2749-2755

  Yong, Mei ^a   Kaste, Markku ^b  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Hyperglycemia; Ischemic stroke; Outcome; Prediction; Recombinant tissue plasminogen activator; Serum glucose

Indexed keywords

GLUCOSE; BIOLOGICAL MARKER; FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

ADVERSE OUTCOME; AGED; ARTICLE; BARTHEL INDEX; BRAIN HEMORRHAGE; BRAIN INFARCTION; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; DEATH; DIABETIC PATIENT; DISEASE ASSOCIATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PATIENT MONITORING; PRIORITY JOURNAL; PROGNOSIS; RANKIN SCALE; RISK ASSESSMENT; STROKE PATIENT; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; DOUBLE BLIND PROCEDURE; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; STROKE;

AGED; BIOLOGICAL MARKERS; BLOOD GLUCOSE; DIABETES MELLITUS; DOUBLE-BLIND METHOD; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; HYPERGLYCEMIA; MALE; RECOVERY OF FUNCTION; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 54049111024     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.514307     Document Type: Article

References (34)

1. Kiers L, Davis SM, Larkins R, Hopper J, Tress B, Rossiter SC, Carlin J, Ratnaike S. Stroke topography and outcome in relation to hyperglycaemia and diabetes. J Neurol Neurosurg Psychiatry. 1992;55:263-270.
2. Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyper-glycemia and prognosis of stroke in diabetic and nondiabetic patients: a systematic overview. Stroke. 2001;32:2426-2432.
3. Tracey F, Stout RW. Hyperglycemia in the acute phase of stroke and stress response. Stroke. 1994;25:424-425.
4. Counsell C, McDowall M, Dennis M. Hyperglycaemia after scute stroke. Other models find that hyperglycaemia is not independent predictor. BMJ. 1997;314:810-811.
5. Anderson RE, Tan WK, Martin HS, Meyer FB. Effects of glucose and PaO2 modulation on cortical intracellular acidosis, NADH redox state, and infarction in the ischemic penumbra. Stroke. 199;30:160-170.
6. Kernan WN, Inzucci SE, Viscoli CM, Brass LM, Bravata DM, Horwitz RI. Insulin resistance and risk for stroke. Neurology. 2002;59:809-815.
7. Kawai N, Keep RF, Benz AL. Hyperglycemia and the vascular effects of cerebral ischemia. Stroke. 1997;28:149-154.
8. Steinberg HO, Tarshoy M, Monestel R, Hook G, Gronin J, Johnson A, Bayazeed B, Baron AD. Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest. 1997;100:1230-1239.
9. Weier CJ, Murray GD, Dyker AG, Lees KR. Is hyperglycemia an independent predictor of poor outcome after acute stroke? Results of a long term follow up study. BMJ. 1997;314:1303-1306.
10. Christensen H, Boysen G. Blood glucose increase early after stroke onset: a study on serial measurements of blood glucose in acute stroke. Eur J Neurol. 2002;9:297-301.
11. Baird TA, Parsons MW, Phanh T, Butcher KS, Desmond PM, Tress BM, Colman PG, Chambers BR, Davis SM. Persistent poststroke hyper-glycemia is independently associated with infarct expansion and worse clinical outcome. Stroke. 2003;34:2208-2214.
12. Levine SR, Welch KM, Helpern JA, Chopp M, Bruce R, Selwa J, Smith MB. Prolonged deterioration of ischemic brain energy metabolism and acidosis associated with hyperglycemia: human cerebral infarction studied by serial 31PNMR spectroscopy. Ann Neurol. 1988;23:416-418.
13. Alvarez-Sabin J, Molina CA, Montaner J, Arenillas JF, Huertas R, Ribo M, Codina A, Quintana M. Effects of admission hyperglycemia on stroke outcome in reperfused tissue plasminogen activator-treated patients. Stroke. 2003;34:1235-1241.
14. Bruno A, Levine SR, Frankel MR, Brott TG, Lin Y, Tilley BC, Lyden PD, Broderick JP, Kwiatkowski TG, Fineberg SE; the NINDS rt-PA Stroke Study Group. Admission glucose level and clinical outcomes in the NINDS rt-PA Trial. Neurology. 2002;59:669-674.
15. Demchuk AM, Morgenstern LB, Krieger DW, Chi TL, Hu W, Wein TH, Hardy RJ, Grotta JC, Buchan AM. Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke. Stroke. 1999;30:34 -39.
16. Bruno A, Biller J, Adams HP, Clarke WR, Woolson RF, Williams LS, Hansen MD; for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. Acute blood glucose level and outcome from ischemic stroke. Neurology. 1999;52:280-284.
17. Hacke W, Kaste M, Fieschi C, von Kummer R, Davalos A, Meier D, Larrue V, Bluhmki E, Davis S, Donnan G, Schneider D, Diez-Tejedor E, Trouillas P; for the Second European-Australasian Acute Stroke Study Investigators. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischemic stroke (ECASS II). Lancet. 1998;352:1245-1251.
18. Larrue V, von Kummer R, Müller A, Bluhmki E. Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian acute stroke study (ECASS II). Stroke. 2001;32: 438-441.
19. Kreisel SH, Bazner H, Hennerici MG. Pathophysiology of stroke rehabilitation: temporal aspects of neuro-functional recovery. Cerebrovasc Dis. 2006;21:6-17.
20. R User's Guide. Version 6, 4th ed, vol 2. Cary, NC: SAS Institute Inc; 1989.
21. Oppenheimer SM, Hoffbrand BI, Oswald GA, Yadkin JS. Diabetes mellitus and early mortality from stroke. BMJ. 1985;291:1014-1015.
22. Emara MK, Saadah AM, Tohfa YA, Guindi RT, Gupta RK, Senthilselvan A. The haematocrit value in diabetic patients with ischaemic stroke. Diabetes Res. 1989;12:189-192.
23. Woo J, Lam CW, Kay R, Wong AH, Teoh R, Nicholls G. The influence of hyperglycemia and diabetes mellitus on immediate and 3-month morbidity and mortality after acute stroke. Arch Neurol. 1990;47:1174 -1177.
24. Said G. Diabetic neuropathy - a review. Nat Clin Pract Neurol. 2007;3: 331-340.
25. Baird TA, Parsons MW, Barber PA, Butcher KS, Desmond PM, Tress BM, Colman PG, Jerums G, Chambers BR, Davis SM. The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome. J Clin Neurosci. 2002;9:618-626.
26. Candelise L, Landi G, Orazio EN, Boccardi E. Prognostic significance of hyperglycemia in acute stroke. Arch Neurol. 1985;42:661-663.
27. Toni D, Sacchetti ML, Argentino C, Gentile M, Cavalletti C, Frontoni M, Fieschi C. Does hyperglycemia play a role on the outcome of acute ischemic stroke patients? J Neurol. 1992;239:382-386.
28. Van Kooten F, Hoogerbrugge N, Naarding P, Koudstaal PJ. Hyperglycemia in the acute phase of stroke is not caused by stress. Stroke. 1993;24:1129-1132.
29. Wass CT, Lanier WL. Glucose modulation of ischaemic brain injury. Mayo Clin Proc. 1996;71:801-812.
30. Kent DM, Hinchey J, Price LL, Levine SR, Selker HP. In acute ischemic stroke, are asymptomatic intracranial hemorrhages clinically innocuous? Stroke. 2004;35:1141-1146.
31. Dzialowski I, Pexman W, Barber PA, Demchuk AM, Buchan AM, Hill MD; on behalf of the CASES Investigators. Asymptomatic hemorrhage after thrombolysis may not be benign. Prognosis by hemorrhage type in the Canadian Alteplase for Stroke Effectiveness Study Registry. Stroke. 2007;38:75-79.
32. Thomalla G, Sobesky J, Köhrmann M, Fiebach JB, Fiehler J, Zaro Weber O, Kruetzelmann A, Kucinski T, Rosenkranz M, Röther J, Schellinger PD. Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours. Stroke. 2007;38:313-318.
33. Gray CS, Hildreth AJ, Alberti GKMM, O'Connell JE; on behalf of the GIST Collaboration. Poststroke hyperglycemia - natural history and immediate management. Stroke. 2004;35:122-126.
34. Gray CS, Hildreth AJ, Sandercock PA, O'Connell JE, Johnston DE, Cartlidge NEF, Bamford JM, James OF, Alberti KG; the GIST Trialists Collaboration. Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK). Lancet Neurol. 2007;6:397-406.