Urokinase induces survival or pro-apoptotic signals in human mesangial cells depending on the apoptotic stimulus

Biochemical Journal

Volumn 415, Issue 2, 2008, Pages 265-273

  Tkachuk, Natalia ^a   Kiyan, Julia ^a   Tkachuk, Sergey ^a   Kiyan, Roman ^b   Shushakova, Nelli ^c   Haller, Hermann ^a   Dumler, Inna ^a,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Lazer Zentrum Hannover   (Germany)

^c Phenos GmbH   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Bcl 2 Bcl XL antagonist; Causing cell death (BAD) protein; Cell death; Cell signalling; Cell survival; Mannose 6 phosphate (M6P) insulin like growth factor 2 receptor (IGF2R); Urokinase type plasminogen activator (uPA)

Indexed keywords

AMINES; ANIMAL CELL CULTURE; BIOACTIVITY; CELL DEATH; CELL GROWTH; CYTOLOGY; GLUCOSE; HORMONES; INSULIN; PEPTIDES; SUGAR (SUCROSE);

BCL-2/BCL-XL-ANTAGONIST; CAUSING CELL DEATH (BAD) PROTEIN; CELL SURVIVAL; MANNOSE 6-PHOSPHATE (M6P)/INSULIN-LIKE GROWTH FACTOR 2 RECEPTOR (IGF2R); UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA);

CELLS;

ARGININE; ASPARTIC ACID; GLUCOSE; GLYCINE; MANNOSE 6 PHOSPHATE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAD; PROTEIN KINASE B; SOMATOMEDIN B RECEPTOR; UROKINASE; UROKINASE RECEPTOR;

APOPTOSIS; ARTICLE; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MESANGIUM CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCOSE; HUMANS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; MANNOSEPHOSPHATES; MESANGIAL CELLS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NUCLEAR ENVELOPE; OLIGOPEPTIDES; ONCOGENE PROTEIN V-AKT; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; SIGNAL TRANSDUCTION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 54049101996     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071652     Document Type: Article

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