Morphological and structural properties of two-phase coaxial jet electrosprayed BSA-PLA capsules

Journal of Microencapsulation

Volumn 25, Issue 7, 2008, Pages 469-477

  Xu, Yixiang ^a   Hanna, Milford A ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

BSA poly(lactide); Capsule; Electrospray; Encapsulation; Morphology; Structure; Two phase coaxial jet

Indexed keywords

BOVINE SERUM ALBUMIN; NANOPARTICLE; POLYLACTIDE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; ELECTRIC CONDUCTIVITY; ELECTRIC FIELD; ELECTRIC POTENTIAL; ELECTROSPRAY; FLOW RATE; INFRARED SPECTROSCOPY; JET INJECTOR; MELTING POINT; MICROCAPSULE; MICROENCAPSULATION; NANOTECHNOLOGY; PARTICLE SIZE; STRUCTURE ANALYSIS; SURFACE PROPERTY; VISCOSITY;

CAPSULES; ELECTRIC CONDUCTIVITY; KINETICS; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; POLYESTERS; SERUM ALBUMIN, BOVINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; VISCOSITY;

EID: 54049096689     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040802049513     Document Type: Article

References (27)

1. Amsden, BG and Goosen, MFA (1997) An examination of factors affecting the size, distribution and release characteristics of polymer microbeads made using electrostatics. J Contr Rel, 43, pp. 183-196.
2. Bocanegra, R., Gaonkar, AG, Barrero, A., Loscertales IG. Pechack, D and Marquez, M. (2005) Production of cocoa butter microcapsules using an electrospray process. J Food Sci, 70, pp. 492-497.
3. Chen, XP, Jia, LB, Yin, XZ and Cheng, JS (2005) Spraying modes in coaxial jet electrospray with outer driving liquid. Phys Fluids, 17, p. 32101.
4. Cui, WG, Li, XH, Zhu, XL, Yu, G., Zhou, SB and Weng, J. (2006) Investigation of drug release and matrix degradation of electrospun poly (DL-lactide) fibers with paacetanol inoculation. Biomacromolecules, 7, pp. 1623-1629.
5. Dersch, R., Steinhart, M., Boudriot, U., Greiner, A. and Wendorff, JH (2005) Nanoprocessing of polymers: Applications in medicine, sensors, catalysis, photonics. Polym Adv Technol, 16, pp. 276-282.
6. Farook, U., Edirisinghe, MJ, Stride, E. and Colombo, P. (2008) Novel co-axial electrohydrodynamic in-situ preparation if liquid-filled polymer-shell microspheres for biomedical application. J Microencapsulation
7. Farook, U., Stride, E. and Edirisinghe, MJ (2007) Microbubbling by co-axial electrohydrodynamic atomization. Med Biol Eng Comp, 45, pp. 781-789.
8. Gaber, MH (2005) Effect of γ-irradiation on the molecular properties of bovine serum albumin. J Biosci Bioeng, 100, pp. 203-206.
9. Huang, Z-M, He, C-L, Yang, AZ, Zhang, YZ, Han, X-J and Yin, JL (2006) Encapsulation drugs in biodegradable ultrafine fibers through co-axial electrospinning. J Biomed Mater Res, 77, pp. 169-179.
10. Jayasinghe, SN (2007) Submerged electrosprays: A versatile approach for microencapsulation. J Microencapsulation, 24, pp. 430-444.
11. Kuo, SM, Niu, G., Chang, SJ, Kuo, CH and Bair, MS (2004) A one-step method for fabricating chitosan microspheres. J Appl Polym Sci, 94, pp. 2150-2157.
12. Liu, JQ, Tian, JN, He, WY, Xie, JP, Hu, ZD and Chen, XG (2004) Spectofluorimetric study of the binding of daphnetin to bovine serum albumin. J Pharm Biomed Anal, 35, pp. 671-677.
13. Lopez-Herrera, JM, Barrero, A., Lopez, A., Loscertales, IG and Marquez, M. (2003) Coaxial jets generated from electrified Taylor cones. Scaling laws. Aerosol Sci, 34, pp. 535-552.
14. Loscertales, IG, Barrero, A., Guerrero, I., Cortijo, R., Marquez, M. and Ganan-Calvo, AM (2002) Micro/nano encapsulation via electrified coaxial liquid jets. Science, 295, pp. 1695-1698.
15. Nagare, S., Sagawa, J. and Senna, M. (2006) Chemical and structural properties of drug-protein nanocomposites prepared by pulsed laser deposition from conjugated targets. J Nanoparticle Res, 8, pp. 37-42.
16. Pareta, P., Brindley, A., Edirisinghe, MJ and Jayasinghe, SN (2005) Electrohydrodynamic atomization of protein (bovine serum albumin). J Mater Sci Mater Med, 16, pp. 919-925.
17. Pareta, R. and Edirisinghe, MJ (2006) A novel method for the preparation of biodegradable microspheres for protein drug delivery. J R Soc Interface, 3, pp. 573-582.
18. Rai, M., Shukla, C., Muthukumarappan, K. and Julson, J. Comparison between drum and pulverized air dried distilled grain extrudates using single screw extruder. ASAE Annual International Meeting Ottawa, Ontario, Canada
19. Singh, S., Raina, CS, Bawa, AS and Saxena, DC (2004) Sweet potato-based pasta product: Optimization of ingredient levels using response surface methodology. Int J Food Sci Technol, 39, pp. 191-200.
20. Utada, AS, Lorenceau, E., Link, DR, Kaplan, PD, Stone, HA and Weitz, DA (2005) Monodisperse double emulsion generated from a microcapillary device. Science, 308, pp. 537-541.
21. Xiao, YM, Xu, YZ, Lu, J., Zhu, XD, Fan, HS and Zhang, XD (2007) Preparation and characterization of collagen-modified polylactide microparticles. Mater Let, 61, pp. 2601-2605.
22. Xie, JW, Marijnissen J, CM and Wang, C-H (2006) Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug totreat C6 glioma in vitro. Biomaterials, 27, pp. 3321-3332.
23. Xu, YX and Hanna, MA (2006) Electrospray encapsulation of water-soluble protein with polylactide. Effects of formulations on encapsulation efficiency and release. Int J Pharm, 320, pp. 30-36.
24. Xu, YX and Hanna, MA (2007) Synthesis and characterization of tripolyphosphate (TPP) cross-linked chitosan capsules using electrospraying technique. J Microencapsulation, 24, pp. 143-151.
25. Xu, YX, Skotak, M. and Hanna, MA (2006) Electrospray encapsulation of water-soluble protein with polylactide. I Effects of formulations and process on morphology and particle size. J Microencapsulation, 23, pp. 69-78.
26. Yang, YY, Chung, TS and Ng, NP (2001) Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/ evaporation methods. Biomaterials, 22, pp. 231-241.
27. Yu, JH, Fridrikh, SV and Rutledge, GC (2004) Production of submicrometer diameter fibers by two-fluid electrospinning. Adv Mater, 16, pp. 1562-1566.