-
1
-
-
33750378183
-
Dendritic-cell interactions with HIV: Infection and viral dissemination
-
Wu L, KewalRamani VN. Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol 2006; 6:859-868.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 859-868
-
-
Wu, L.1
KewalRamani, V.N.2
-
2
-
-
33646342770
-
Microbicides and other topical strategies to prevent vaginal transmission of HIV
-
Lederman MM, Offord RE, Hartley O. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nat Rev Immunol 2006; 6:371-382.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 371-382
-
-
Lederman, M.M.1
Offord, R.E.2
Hartley, O.3
-
3
-
-
34147186281
-
Current concepts of HIV transmission
-
An interesting review highlights current understanding of HIV-1 mucosal transmission
-
Morrow G, Vachot L, Vagenas P, et al. Current concepts of HIV transmission. Curr HIV/AIDS Rep 2007; 4:29-35. An interesting review highlights current understanding of HIV-1 mucosal transmission.
-
(2007)
Curr HIV/AIDS Rep
, vol.4
, pp. 29-35
-
-
Morrow, G.1
Vachot, L.2
Vagenas, P.3
-
5
-
-
12144290772
-
Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells
-
Turville SG, Santos JJ, Frank I, et al. Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells. Blood 2004; 103:2170-2179.
-
(2004)
Blood
, vol.103
, pp. 2170-2179
-
-
Turville, S.G.1
Santos, J.J.2
Frank, I.3
-
6
-
-
27144465182
-
Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer
-
Turville SG, Vermeire K, Balzarini J, et al. Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer. J Virol 2005; 79:13519-13527.
-
(2005)
J Virol
, vol.79
, pp. 13519-13527
-
-
Turville, S.G.1
Vermeire, K.2
Balzarini, J.3
-
7
-
-
34548162813
-
Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells
-
A functional comparative study shows distinct efficiencies and mechanisms of HIV-1 trans-infection mediated by immature and mature dendritic cells. This study also reports dendritic cell-target cell contact is required for dendritic cell-mediated HIV-1 transmission
-
Wang JH, Janas AM, Olson WJ, et al. Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells. J Virol 2007; 81:8933-8943. A functional comparative study shows distinct efficiencies and mechanisms of HIV-1 trans-infection mediated by immature and mature dendritic cells. This study also reports dendritic cell-target cell contact is required for dendritic cell-mediated HIV-1 transmission.
-
(2007)
J Virol
, vol.81
, pp. 8933-8943
-
-
Wang, J.H.1
Janas, A.M.2
Olson, W.J.3
-
8
-
-
34447270265
-
Maturation of blood derived dendritic cells enhances HIV-1 capture and transmission
-
Izquierdo-Useros N, Blanco J, Erkizia I, et al. Maturation of blood derived dendritic cells enhances HIV-1 capture and transmission. J Virol 2007; 81:7559-7570.
-
(2007)
J Virol
, vol.81
, pp. 7559-7570
-
-
Izquierdo-Useros, N.1
Blanco, J.2
Erkizia, I.3
-
9
-
-
35148886657
-
-
Dong C, Janas AM, Wang J-H, et al. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol 2007; 81:11352-11362. This report is a comparative analysis of cis and trans-infections of HIV-1 mediated by different dendritic cell subsets, suggesting that these two infection pathways are dissociable.
-
Dong C, Janas AM, Wang J-H, et al. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol 2007; 81:11352-11362. This report is a comparative analysis of cis and trans-infections of HIV-1 mediated by different dendritic cell subsets, suggesting that these two infection pathways are dissociable.
-
-
-
-
10
-
-
34250834290
-
Activated CD34-derived Langerhans cells mediate transinfection with human immunodeficiency virus
-
Fahrbach KM, Barry SM, Ayehunie S, et al. Activated CD34-derived Langerhans cells mediate transinfection with human immunodeficiency virus. J Virol 2007; 81:6858-6868.
-
(2007)
J Virol
, vol.81
, pp. 6858-6868
-
-
Fahrbach, K.M.1
Barry, S.M.2
Ayehunie, S.3
-
11
-
-
43949133000
-
A fusion inhibitor prevents dendritic cell (DC) spread of immunodeficiency viruses but not DC activation of virus-specific T cells
-
Frank I, Stossel H, Getti A, et al. A fusion inhibitor prevents dendritic cell (DC) spread of immunodeficiency viruses but not DC activation of virus-specific T cells. J Virol 2008; 82:5329-5339.
-
(2008)
J Virol
, vol.82
, pp. 5329-5339
-
-
Frank, I.1
Stossel, H.2
Getti, A.3
-
12
-
-
33847755116
-
Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
-
This study showed that langerin mediates HIV-1 internalization and intracellular degradation in skin-derived Langerhans cells, thereby inhibiting HIV-1 replication and transmission
-
de Witte L, Nabatov A, Pion M, et al. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. Nat Med 2007; 13:367-371. This study showed that langerin mediates HIV-1 internalization and intracellular degradation in skin-derived Langerhans cells, thereby inhibiting HIV-1 replication and transmission.
-
(2007)
Nat Med
, vol.13
, pp. 367-371
-
-
de Witte, L.1
Nabatov, A.2
Pion, M.3
-
13
-
-
44349117379
-
Significant virus replication in Langerhans cells following application of HIV to abraded skin: Relevance to occupational transmission of HIV
-
A report indicates that epithelial Langerhans cells account for over 95% of HIV-1 dissemination in human skin explants
-
Kawamura T, Koyanagi Y, Nakamura Y, et al. Significant virus replication in Langerhans cells following application of HIV to abraded skin: relevance to occupational transmission of HIV. J Immunol 2008; 180:3297-3304. A report indicates that epithelial Langerhans cells account for over 95% of HIV-1 dissemination in human skin explants.
-
(2008)
J Immunol
, vol.180
, pp. 3297-3304
-
-
Kawamura, T.1
Koyanagi, Y.2
Nakamura, Y.3
-
14
-
-
33846495455
-
In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions
-
Cavrois M, Neidleman J, Kreisberg JF, et al. In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog 2007; 3:e4.
-
(2007)
PLoS Pathog
, vol.3
-
-
Cavrois, M.1
Neidleman, J.2
Kreisberg, J.F.3
-
15
-
-
33845803152
-
Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells
-
Bobardt MD, Chatterji U, Selvarajah S, et al. Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells. J Virol 2007; 81:395-405.
-
(2007)
J Virol
, vol.81
, pp. 395-405
-
-
Bobardt, M.D.1
Chatterji, U.2
Selvarajah, S.3
-
16
-
-
36048945481
-
The interaction of HIV with dendritic cells: Outcomes and pathways
-
Piguet V, Steinman RM. The interaction of HIV with dendritic cells: outcomes and pathways. Trends Immunol 2007; 28:503-510.
-
(2007)
Trends Immunol
, vol.28
, pp. 503-510
-
-
Piguet, V.1
Steinman, R.M.2
-
17
-
-
0038025223
-
Recruitment of HIV and its receptors to dendritic cell-T cell junctions
-
McDonald D, Wu L, Bohks SM, et al. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 2003; 300:1295-1297.
-
(2003)
Science
, vol.300
, pp. 1295-1297
-
-
McDonald, D.1
Wu, L.2
Bohks, S.M.3
-
18
-
-
85047690554
-
Dangerous liaisons at the virological synapse
-
Piguet V, Sattentau Q. Dangerous liaisons at the virological synapse. J Clin Invest 2004; 114:605-610.
-
(2004)
J Clin Invest
, vol.114
, pp. 605-610
-
-
Piguet, V.1
Sattentau, Q.2
-
19
-
-
33847197497
-
Dendritic cell-mediated transenhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN
-
Boggiano C, Manel N, Littman DR. Dendritic cell-mediated transenhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN. J Virol 2007; 81:2519-2523.
-
(2007)
J Virol
, vol.81
, pp. 2519-2523
-
-
Boggiano, C.1
Manel, N.2
Littman, D.R.3
-
20
-
-
37649009793
-
Syndecan-3 is a dendritic cellspecific attachment receptor for HIV-1
-
de Witte L, Bobardt M, Chatterji U, et al. Syndecan-3 is a dendritic cellspecific attachment receptor for HIV-1. Proc Natl Acad Sci U S A 2007; 104:19464-19469.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19464-19469
-
-
de Witte, L.1
Bobardt, M.2
Chatterji, U.3
-
21
-
-
33847149747
-
Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells
-
Smith AL, Ganesh L, Leung K, et al. Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. J Exp Med 2007; 204:421-430.
-
(2007)
J Exp Med
, vol.204
, pp. 421-430
-
-
Smith, A.L.1
Ganesh, L.2
Leung, K.3
-
22
-
-
34249088361
-
Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication
-
Hodges A, Sharrocks K, Edelmann M, et al. Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. Nat Immunol 2007; 8:569-577.
-
(2007)
Nat Immunol
, vol.8
, pp. 569-577
-
-
Hodges, A.1
Sharrocks, K.2
Edelmann, M.3
-
23
-
-
34248544993
-
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB
-
Gringhuis SI, den Dunnen J, Litjens M, et al. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. Immunity 2007; 26:605-616.
-
(2007)
Immunity
, vol.26
, pp. 605-616
-
-
Gringhuis, S.I.1
den Dunnen, J.2
Litjens, M.3
-
24
-
-
21144438323
-
HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse
-
Garcia E, Pion M, Pelchen-Matthews A, et al. HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic 2005; 6:488-501.
-
(2005)
Traffic
, vol.6
, pp. 488-501
-
-
Garcia, E.1
Pion, M.2
Pelchen-Matthews, A.3
-
25
-
-
31444453892
-
Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
-
Wiley RD, Gummuluru S. Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc Natl Acad Sci U S A 2006; 103:738-743.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 738-743
-
-
Wiley, R.D.1
Gummuluru, S.2
-
26
-
-
38149040172
-
HIV-1 replication in dendritic cells occurs via a tetraspanin-containing compartment enriched in AP-3
-
Garcia E, Nikolic DS, Piguet V. HIV-1 replication in dendritic cells occurs via a tetraspanin-containing compartment enriched in AP-3. Traffic 2008; 9:200-214.
-
(2008)
Traffic
, vol.9
, pp. 200-214
-
-
Garcia, E.1
Nikolic, D.S.2
Piguet, V.3
-
27
-
-
33748626539
-
Differential susceptibility of naive, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission
-
Groot F, van Capel TM, Schuitemaker J, et al. Differential susceptibility of naive, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission. Retrovirology 2006; 3:52.
-
(2006)
Retrovirology
, vol.3
, pp. 52
-
-
Groot, F.1
van Capel, T.M.2
Schuitemaker, J.3
-
28
-
-
33847219326
-
Preferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes
-
+ T cells, suggesting a role of dendritic cells in R5 HIV-1 selection during parenteral transmission
-
+ T cells, suggesting a role of dendritic cells in R5 HIV-1 selection during parenteral transmission.
-
(2007)
J Virol
, vol.81
, pp. 2297-2306
-
-
Cameron, P.U.1
Handley, A.J.2
Baylis, D.C.3
-
29
-
-
33847237613
-
-
Wang JH, Janas AM, Olson WJ, et al. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol 2007; 81:2497-2507. This study suggested that HIV-1 Nef enhances dendritic cell-mediated HIV-1 transmission, and that CD4 coexpression modulates DC-SIGN-mediated viral transmission.
-
Wang JH, Janas AM, Olson WJ, et al. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol 2007; 81:2497-2507. This study suggested that HIV-1 Nef enhances dendritic cell-mediated HIV-1 transmission, and that CD4 coexpression modulates DC-SIGN-mediated viral transmission.
-
-
-
-
30
-
-
17444371691
-
Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes
-
Nobile C, Petit C, Moris A, et al. Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes. J Virol 2005; 79:5386-5399.
-
(2005)
J Virol
, vol.79
, pp. 5386-5399
-
-
Nobile, C.1
Petit, C.2
Moris, A.3
-
31
-
-
32444448944
-
Human immunodeficiency virus fusion to dendritic cells declines as cells mature
-
Cavrois M, Neidleman J, Kreisberg JF, et al. Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol 2006; 80:1992-1999.
-
(2006)
J Virol
, vol.80
, pp. 1992-1999
-
-
Cavrois, M.1
Neidleman, J.2
Kreisberg, J.F.3
-
32
-
-
33644749292
-
Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells
-
Burleigh L, Lozach P-Y, Schiffer C, et al. Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells. J Virol 2006; 80:2949-2957.
-
(2006)
J Virol
, vol.80
, pp. 2949-2957
-
-
Burleigh, L.1
Lozach, P.-Y.2
Schiffer, C.3
-
33
-
-
33846258118
-
Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels
-
Pion M, Arrighi JF, Jiang J, et al. Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels. J Invest Dermatol 2007; 127:319-323.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 319-323
-
-
Pion, M.1
Arrighi, J.F.2
Jiang, J.3
-
34
-
-
43249124385
-
Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry
-
Janas AM, Dong C, Wang JH, et al. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry. Virology 2008; 375:442-451.
-
(2008)
Virology
, vol.375
, pp. 442-451
-
-
Janas, A.M.1
Dong, C.2
Wang, J.H.3
-
35
-
-
1642392156
-
DC-SIGN promotes exogenous MHC-Irestricted HIV-1 antigen presentation
-
Moris A, Nobile C, Buseyne F, et al. DC-SIGN promotes exogenous MHC-Irestricted HIV-1 antigen presentation. Blood 2004; 103:2648-2654.
-
(2004)
Blood
, vol.103
, pp. 2648-2654
-
-
Moris, A.1
Nobile, C.2
Buseyne, F.3
-
36
-
-
33745070227
-
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
-
Schindler M, Munch J, Kutsch O, et al. Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell 2006; 125:1055-1067.
-
(2006)
Cell
, vol.125
, pp. 1055-1067
-
-
Schindler, M.1
Munch, J.2
Kutsch, O.3
-
37
-
-
37049003772
-
Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection
-
Duvall MG, Lore K, Blaak H, et al. Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol 2007; 81:13486-13498.
-
(2007)
J Virol
, vol.81
, pp. 13486-13498
-
-
Duvall, M.G.1
Lore, K.2
Blaak, H.3
-
38
-
-
36049037370
-
Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses
-
This study estimated that cell-associated transfer of HIV-1 through virological synapses can be 92 to 18 600-fold more efficient than that of cell-free virus
-
Chen P, Hubner W, Spinelli MA, et al. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol 2007; 81:12582-12595. This study estimated that cell-associated transfer of HIV-1 through virological synapses can be 92 to 18 600-fold more efficient than that of cell-free virus.
-
(2007)
J Virol
, vol.81
, pp. 12582-12595
-
-
Chen, P.1
Hubner, W.2
Spinelli, M.A.3
-
39
-
-
34249823098
-
Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1
-
Jolly C, Mitar I, Sattentau QJ. Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1. J Virol 2007; 81:5547-5560.
-
(2007)
J Virol
, vol.81
, pp. 5547-5560
-
-
Jolly, C.1
Mitar, I.2
Sattentau, Q.J.3
-
40
-
-
37049018852
-
Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells
-
Jolly C, Mitar I, Sattentau QJ. Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells. J Virol 2007; 81:13916-13921.
-
(2007)
J Virol
, vol.81
, pp. 13916-13921
-
-
Jolly, C.1
Mitar, I.2
Sattentau, Q.J.3
-
41
-
-
33846472081
-
ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation
-
Sol-Foulon N, Sourisseau M, Porrot F, et al. ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation. EMBO J 2007; 26:516-526.
-
(2007)
EMBO J
, vol.26
, pp. 516-526
-
-
Sol-Foulon, N.1
Sourisseau, M.2
Porrot, F.3
-
42
-
-
38849168755
-
-
+ T cells. The efficiency of HIV-1 transmission by nanotubes remains to be determined when compare to virological synapse-mediated viral transfer.
-
+ T cells. The efficiency of HIV-1 transmission by nanotubes remains to be determined when compare to virological synapse-mediated viral transfer.
-
-
-
-
43
-
-
44349094889
-
Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses
-
Groot F, Welsch S, Sattentau QJ. Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses. Blood 2008; 111:4660-4663.
-
(2008)
Blood
, vol.111
, pp. 4660-4663
-
-
Groot, F.1
Welsch, S.2
Sattentau, Q.J.3
-
44
-
-
42949175719
-
-
+ T cells through virological synapses.
-
+ T cells through virological synapses.
-
-
-
-
45
-
-
33845493481
-
Plasma membrane is the site of productive HIV-1 particle assembly
-
Jouvenet N, Neil SJ, Bess C, et al. Plasma membrane is the site of productive HIV-1 particle assembly. PLoS Biol 2006; 4:e435.
-
(2006)
PLoS Biol
, vol.4
-
-
Jouvenet, N.1
Neil, S.J.2
Bess, C.3
-
46
-
-
34047225272
-
HIV-1 buds predominantly at the plasmamembrane of primary human macrophages
-
Welsch S, Keppler OT, Habermann A, et al. HIV-1 buds predominantly at the plasmamembrane of primary human macrophages. PLoS Pathog 2007; 3:e36.
-
(2007)
PLoS Pathog
, vol.3
-
-
Welsch, S.1
Keppler, O.T.2
Habermann, A.3
-
47
-
-
34247529467
-
In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53
-
Deneka M, Pelchen-Matthews A, Byland R, et al. In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. J Cell Biol 2007; 177:329-341.
-
(2007)
J Cell Biol
, vol.177
, pp. 329-341
-
-
Deneka, M.1
Pelchen-Matthews, A.2
Byland, R.3
-
48
-
-
34547687819
-
HIV-1 buds and accumulates in "nonacidic" endosomes of macrophages
-
An ultrastructural study suggested that HIV-1 survives within a nonacidic assembly compartment preventing intracellular degradation
-
Jouve M, Sol-Foulon N, Watson S, et al. HIV-1 buds and accumulates in "nonacidic" endosomes of macrophages. Cell Host Microbe 2007; 2:85-95. An ultrastructural study suggested that HIV-1 survives within a nonacidic assembly compartment preventing intracellular degradation.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 85-95
-
-
Jouve, M.1
Sol-Foulon, N.2
Watson, S.3
-
49
-
-
33745825951
-
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells
-
Savina A, Jancic C, Hugues S, et al. NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell 2006; 126:205-218.
-
(2006)
Cell
, vol.126
, pp. 205-218
-
-
Savina, A.1
Jancic, C.2
Hugues, S.3
-
50
-
-
36549082476
-
Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes
-
Pollicita M, Schols D, Aquaro S, et al. Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes. Virology 2008; 370:382-391.
-
(2008)
Virology
, vol.370
, pp. 382-391
-
-
Pollicita, M.1
Schols, D.2
Aquaro, S.3
-
51
-
-
34848893294
-
Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein
-
Swingler S, Mann AM, Zhou J, et al. Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein. PLoS Pathog 2007; 3:1281-1290.
-
(2007)
PLoS Pathog
, vol.3
, pp. 1281-1290
-
-
Swingler, S.1
Mann, A.M.2
Zhou, J.3
-
52
-
-
39749152063
-
Akt inhibitors as an HIV-1 infected macrophage-specific antiviral therapy
-
Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, et al. Akt inhibitors as an HIV-1 infected macrophage-specific antiviral therapy. Retrovirology 2008; 5:11.
-
(2008)
Retrovirology
, vol.5
, pp. 11
-
-
Chugh, P.1
Bradel-Tretheway, B.2
Monteiro-Filho, C.M.3
-
53
-
-
34648840539
-
Host factors influencing susceptibility to HIV infection and AIDS progression
-
This is a comprehensive review on host factors affecting susceptibility to HIV infection and AIDS progression
-
Lama J, Planelles V. Host factors influencing susceptibility to HIV infection and AIDS progression. Retrovirology 2007; 4:52. This is a comprehensive review on host factors affecting susceptibility to HIV infection and AIDS progression.
-
(2007)
Retrovirology
, vol.4
, pp. 52
-
-
Lama, J.1
Planelles, V.2
-
54
-
-
36849093472
-
Semen-derived amyloid fibrils drastically enhance HIV infection
-
This study reported that human semen-derived amyloid fibrils can enhance HIV-1 infectivity by more than 100 000-fold under the experimental conditions. The mechanisms underlying the formation of the amyloid fibrils and the enhancement of HIV-1 infectivity remain to be elucidated
-
Münch J, Rucker E, Standker L, et al. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 2007; 131:1059-1071. This study reported that human semen-derived amyloid fibrils can enhance HIV-1 infectivity by more than 100 000-fold under the experimental conditions. The mechanisms underlying the formation of the amyloid fibrils and the enhancement of HIV-1 infectivity remain to be elucidated.
-
(2007)
Cell
, vol.131
, pp. 1059-1071
-
-
Münch, J.1
Rucker, E.2
Standker, L.3
-
55
-
-
37049027132
-
Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN
-
Sabatté J, Ceballos A, Raiden S, et al. Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN. J Virol 2007; 81:13723-13734.
-
(2007)
J Virol
, vol.81
, pp. 13723-13734
-
-
Sabatté, J.1
Ceballos, A.2
Raiden, S.3
-
56
-
-
33748687966
-
Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: Transmission facilitation versus replication inhibition
-
Groot F, van Capel TM, Kapsenberg ML, et al. Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition. Blood 2006; 108:1957-1964.
-
(2006)
Blood
, vol.108
, pp. 1957-1964
-
-
Groot, F.1
van Capel, T.M.2
Kapsenberg, M.L.3
-
57
-
-
40349111591
-
-
Meyers JH, Justement JS, Hallahan CW, et al. Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLoS ONE 2007; 2:e458. A study suggested that plasmacytoid dendritic cells can be important mediators of innate anti-HIV-1 immunity.
-
Meyers JH, Justement JS, Hallahan CW, et al. Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLoS ONE 2007; 2:e458. A study suggested that plasmacytoid dendritic cells can be important mediators of innate anti-HIV-1 immunity.
-
-
-
-
58
-
-
33845906383
-
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
-
Pion M, Granelli-Piperno A, Mangeat B, et al. APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection. J Exp Med 2006; 203:2887-2893.
-
(2006)
J Exp Med
, vol.203
, pp. 2887-2893
-
-
Pion, M.1
Granelli-Piperno, A.2
Mangeat, B.3
-
59
-
-
34347371436
-
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression
-
Peng G, Greenwell-Wild T, Nares S, et al. Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression. Blood 2007; 110:393-400.
-
(2007)
Blood
, vol.110
, pp. 393-400
-
-
Peng, G.1
Greenwell-Wild, T.2
Nares, S.3
-
60
-
-
42449141206
-
APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells
-
Wang FX, Huang J, Zhang H, et al. APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells. J Gen Virol 2008; 89:722-730.
-
(2008)
J Gen Virol
, vol.89
, pp. 722-730
-
-
Wang, F.X.1
Huang, J.2
Zhang, H.3
-
61
-
-
33847617830
-
HIV-1 gp120 inhibits TLR9-mediated activation and IFN-a secretion in plasmacytoid dendritic cells
-
This study suggested that HIV-1 gp120 antagonizes the innate anti-HIV-1 activity of plasmacytoid dendritic cells
-
Martinelli E, Cicala C, Van Ryk D, et al. HIV-1 gp120 inhibits TLR9-mediated activation and IFN-a secretion in plasmacytoid dendritic cells. Proc Natl Acad Sci U S A 2007; 104:3396-3401. This study suggested that HIV-1 gp120 antagonizes the innate anti-HIV-1 activity of plasmacytoid dendritic cells.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3396-3401
-
-
Martinelli, E.1
Cicala, C.2
Van Ryk, D.3
-
62
-
-
34548021883
-
Retroviral proteins that interact with the host cell cytoskeleton
-
Naghavi MH, Goff SP. Retroviral proteins that interact with the host cell cytoskeleton. Curr Opin Immunol 2007; 19:402-407.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 402-407
-
-
Naghavi, M.H.1
Goff, S.P.2
-
63
-
-
35648969165
-
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses
-
Dustin ML. Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses. Curr Opin Cell Biol 2007; 19:529-533.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 529-533
-
-
Dustin, M.L.1
-
64
-
-
33947591273
-
Modulation of the immunological synapse: A key to HIV-1 pathogenesis?
-
Fackler OT, Alcover A, Schwartz O. Modulation of the immunological synapse: a key to HIV-1 pathogenesis? Nat Rev Immunol 2007; 7:310-317.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 310-317
-
-
Fackler, O.T.1
Alcover, A.2
Schwartz, O.3
-
65
-
-
33646552033
-
Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
-
Thoulouze MI, Sol-Foulon N, Blanchet F, et al. Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse. Immunity 2006; 24:547-561.
-
(2006)
Immunity
, vol.24
, pp. 547-561
-
-
Thoulouze, M.I.1
Sol-Foulon, N.2
Blanchet, F.3
-
66
-
-
39349097864
-
-
Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008; 319:921-926. A new study reported over 250 cellular proteins that are required for HIV-1 replication. Despite using a HeLa-cell-derived cell line in the genomic screen, this study provided new insights into further studies of HIV-host interactions.
-
Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008; 319:921-926. A new study reported over 250 cellular proteins that are required for HIV-1 replication. Despite using a HeLa-cell-derived cell line in the genomic screen, this study provided new insights into further studies of HIV-host interactions.
-
-
-
-
67
-
-
38549095979
-
-
Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008; 451:425-430. A host protein termed tetherin is found to inhibit retrovirus release from the cell surface, while HIV-1 Vpu counteracts tetherin's antiviral function. Thus, inhibition of Vpu function could be a potential therapeutic strategy against HIV-1 infection
-
Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008; 451:425-430. A host protein termed tetherin is found to inhibit retrovirus release from the cell surface, while HIV-1 Vpu counteracts tetherin's antiviral function. Thus, inhibition of Vpu function could be a potential therapeutic strategy against HIV-1 infection.
-
-
-
-
68
-
-
41849116366
-
The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
-
Van Damme N, Goff D, Katsura C, et al. The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008; 3:245-252.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 245-252
-
-
Van Damme, N.1
Goff, D.2
Katsura, C.3
-
69
-
-
34247877512
-
Mucosal dendritic cells
-
Iwasaki A. Mucosal dendritic cells. Annu Rev Immunol 2007; 25:381-418.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 381-418
-
-
Iwasaki, A.1
-
70
-
-
33748146017
-
Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T-cell activation, and viral transfer
-
Moris A, Pajot A, Blanchet F, et al. Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T-cell activation, and viral transfer. Blood 2006; 108:1643-1651.
-
(2006)
Blood
, vol.108
, pp. 1643-1651
-
-
Moris, A.1
Pajot, A.2
Blanchet, F.3
-
71
-
-
34447292337
-
Rapid MHC-II antigen presentation of HIV type 1 by human dendritic cells
-
Jones L, McDonald D, Canaday DH. Rapid MHC-II antigen presentation of HIV type 1 by human dendritic cells. AIDS Res Hum Retroviruses 2007; 23:812-816.
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 812-816
-
-
Jones, L.1
McDonald, D.2
Canaday, D.H.3
-
72
-
-
37349066496
-
HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells
-
Shan M, Klasse PJ, Banerjee K, et al. HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells. PLoS Pathog 2007; 3:e169.
-
(2007)
PLoS Pathog
, vol.3
-
-
Shan, M.1
Klasse, P.J.2
Banerjee, K.3
-
73
-
-
33847372187
-
Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes
-
van Montfort T, Nabatov AA, Geijtenbeek TB, et al. Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes. J Immunol 2007; 178:3177-3185.
-
(2007)
J Immunol
, vol.178
, pp. 3177-3185
-
-
van Montfort, T.1
Nabatov, A.A.2
Geijtenbeek, T.B.3
-
74
-
-
34548670468
-
CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entryindependent mechanisms
-
This study suggested that host factors CCL3L1 and CCR5 influence viral pathogenesis through cell-mediated immunity and viral entry-independent mechanisms
-
Dolan MJ, Kulkarni H, Camargo JF, et al. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entryindependent mechanisms. Nat Immunol 2007; 8:1324-1336. This study suggested that host factors CCL3L1 and CCR5 influence viral pathogenesis through cell-mediated immunity and viral entry-independent mechanisms.
-
(2007)
Nat Immunol
, vol.8
, pp. 1324-1336
-
-
Dolan, M.J.1
Kulkarni, H.2
Camargo, J.F.3
-
75
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371.
-
(2006)
Nat Med
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
Price, D.A.2
Schacker, T.W.3
-
76
-
-
39449098115
-
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells
-
+ T cells via HIV-1 gp120 activates or leukocyte function-associated antigen-1, which facilitates VSmediated cell-cell transmission of HIV-1
-
+ T cells via HIV-1 gp120 activates or leukocyte function-associated antigen-1, which facilitates VSmediated cell-cell transmission of HIV-1.
-
(2008)
Nat Immunol
, vol.9
, pp. 301-309
-
-
Arthos, J.1
Cicala, C.2
Martinelli, E.3
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