메뉴 건너뛰기




Volumn 3, Issue 5, 2008, Pages 534-540

Biology of HIV mucosal transmission

Author keywords

Biology; HIV; Infection; Mucosal; Transmission

Indexed keywords

AMYLOID; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CARBOHYDRATE; CD34 ANTIGEN; CD4 ANTIGEN; CELL MEMBRANE PROTEIN; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LANGERIN; LECTIN; MICROBICIDE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SYNDECAN 3; TETHERIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

EID: 54049089700     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0b013e32830634c6     Document Type: Review
Times cited : (41)

References (76)
  • 1
    • 33750378183 scopus 로고    scopus 로고
    • Dendritic-cell interactions with HIV: Infection and viral dissemination
    • Wu L, KewalRamani VN. Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol 2006; 6:859-868.
    • (2006) Nat Rev Immunol , vol.6 , pp. 859-868
    • Wu, L.1    KewalRamani, V.N.2
  • 2
    • 33646342770 scopus 로고    scopus 로고
    • Microbicides and other topical strategies to prevent vaginal transmission of HIV
    • Lederman MM, Offord RE, Hartley O. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nat Rev Immunol 2006; 6:371-382.
    • (2006) Nat Rev Immunol , vol.6 , pp. 371-382
    • Lederman, M.M.1    Offord, R.E.2    Hartley, O.3
  • 3
    • 34147186281 scopus 로고    scopus 로고
    • Current concepts of HIV transmission
    • An interesting review highlights current understanding of HIV-1 mucosal transmission
    • Morrow G, Vachot L, Vagenas P, et al. Current concepts of HIV transmission. Curr HIV/AIDS Rep 2007; 4:29-35. An interesting review highlights current understanding of HIV-1 mucosal transmission.
    • (2007) Curr HIV/AIDS Rep , vol.4 , pp. 29-35
    • Morrow, G.1    Vachot, L.2    Vagenas, P.3
  • 5
    • 12144290772 scopus 로고    scopus 로고
    • Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells
    • Turville SG, Santos JJ, Frank I, et al. Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells. Blood 2004; 103:2170-2179.
    • (2004) Blood , vol.103 , pp. 2170-2179
    • Turville, S.G.1    Santos, J.J.2    Frank, I.3
  • 6
    • 27144465182 scopus 로고    scopus 로고
    • Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer
    • Turville SG, Vermeire K, Balzarini J, et al. Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer. J Virol 2005; 79:13519-13527.
    • (2005) J Virol , vol.79 , pp. 13519-13527
    • Turville, S.G.1    Vermeire, K.2    Balzarini, J.3
  • 7
    • 34548162813 scopus 로고    scopus 로고
    • Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells
    • A functional comparative study shows distinct efficiencies and mechanisms of HIV-1 trans-infection mediated by immature and mature dendritic cells. This study also reports dendritic cell-target cell contact is required for dendritic cell-mediated HIV-1 transmission
    • Wang JH, Janas AM, Olson WJ, et al. Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells. J Virol 2007; 81:8933-8943. A functional comparative study shows distinct efficiencies and mechanisms of HIV-1 trans-infection mediated by immature and mature dendritic cells. This study also reports dendritic cell-target cell contact is required for dendritic cell-mediated HIV-1 transmission.
    • (2007) J Virol , vol.81 , pp. 8933-8943
    • Wang, J.H.1    Janas, A.M.2    Olson, W.J.3
  • 8
    • 34447270265 scopus 로고    scopus 로고
    • Maturation of blood derived dendritic cells enhances HIV-1 capture and transmission
    • Izquierdo-Useros N, Blanco J, Erkizia I, et al. Maturation of blood derived dendritic cells enhances HIV-1 capture and transmission. J Virol 2007; 81:7559-7570.
    • (2007) J Virol , vol.81 , pp. 7559-7570
    • Izquierdo-Useros, N.1    Blanco, J.2    Erkizia, I.3
  • 9
    • 35148886657 scopus 로고    scopus 로고
    • Dong C, Janas AM, Wang J-H, et al. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol 2007; 81:11352-11362. This report is a comparative analysis of cis and trans-infections of HIV-1 mediated by different dendritic cell subsets, suggesting that these two infection pathways are dissociable.
    • Dong C, Janas AM, Wang J-H, et al. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol 2007; 81:11352-11362. This report is a comparative analysis of cis and trans-infections of HIV-1 mediated by different dendritic cell subsets, suggesting that these two infection pathways are dissociable.
  • 10
    • 34250834290 scopus 로고    scopus 로고
    • Activated CD34-derived Langerhans cells mediate transinfection with human immunodeficiency virus
    • Fahrbach KM, Barry SM, Ayehunie S, et al. Activated CD34-derived Langerhans cells mediate transinfection with human immunodeficiency virus. J Virol 2007; 81:6858-6868.
    • (2007) J Virol , vol.81 , pp. 6858-6868
    • Fahrbach, K.M.1    Barry, S.M.2    Ayehunie, S.3
  • 11
    • 43949133000 scopus 로고    scopus 로고
    • A fusion inhibitor prevents dendritic cell (DC) spread of immunodeficiency viruses but not DC activation of virus-specific T cells
    • Frank I, Stossel H, Getti A, et al. A fusion inhibitor prevents dendritic cell (DC) spread of immunodeficiency viruses but not DC activation of virus-specific T cells. J Virol 2008; 82:5329-5339.
    • (2008) J Virol , vol.82 , pp. 5329-5339
    • Frank, I.1    Stossel, H.2    Getti, A.3
  • 12
    • 33847755116 scopus 로고    scopus 로고
    • Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
    • This study showed that langerin mediates HIV-1 internalization and intracellular degradation in skin-derived Langerhans cells, thereby inhibiting HIV-1 replication and transmission
    • de Witte L, Nabatov A, Pion M, et al. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. Nat Med 2007; 13:367-371. This study showed that langerin mediates HIV-1 internalization and intracellular degradation in skin-derived Langerhans cells, thereby inhibiting HIV-1 replication and transmission.
    • (2007) Nat Med , vol.13 , pp. 367-371
    • de Witte, L.1    Nabatov, A.2    Pion, M.3
  • 13
    • 44349117379 scopus 로고    scopus 로고
    • Significant virus replication in Langerhans cells following application of HIV to abraded skin: Relevance to occupational transmission of HIV
    • A report indicates that epithelial Langerhans cells account for over 95% of HIV-1 dissemination in human skin explants
    • Kawamura T, Koyanagi Y, Nakamura Y, et al. Significant virus replication in Langerhans cells following application of HIV to abraded skin: relevance to occupational transmission of HIV. J Immunol 2008; 180:3297-3304. A report indicates that epithelial Langerhans cells account for over 95% of HIV-1 dissemination in human skin explants.
    • (2008) J Immunol , vol.180 , pp. 3297-3304
    • Kawamura, T.1    Koyanagi, Y.2    Nakamura, Y.3
  • 14
    • 33846495455 scopus 로고    scopus 로고
    • In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions
    • Cavrois M, Neidleman J, Kreisberg JF, et al. In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog 2007; 3:e4.
    • (2007) PLoS Pathog , vol.3
    • Cavrois, M.1    Neidleman, J.2    Kreisberg, J.F.3
  • 15
    • 33845803152 scopus 로고    scopus 로고
    • Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells
    • Bobardt MD, Chatterji U, Selvarajah S, et al. Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells. J Virol 2007; 81:395-405.
    • (2007) J Virol , vol.81 , pp. 395-405
    • Bobardt, M.D.1    Chatterji, U.2    Selvarajah, S.3
  • 16
    • 36048945481 scopus 로고    scopus 로고
    • The interaction of HIV with dendritic cells: Outcomes and pathways
    • Piguet V, Steinman RM. The interaction of HIV with dendritic cells: outcomes and pathways. Trends Immunol 2007; 28:503-510.
    • (2007) Trends Immunol , vol.28 , pp. 503-510
    • Piguet, V.1    Steinman, R.M.2
  • 17
    • 0038025223 scopus 로고    scopus 로고
    • Recruitment of HIV and its receptors to dendritic cell-T cell junctions
    • McDonald D, Wu L, Bohks SM, et al. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 2003; 300:1295-1297.
    • (2003) Science , vol.300 , pp. 1295-1297
    • McDonald, D.1    Wu, L.2    Bohks, S.M.3
  • 18
    • 85047690554 scopus 로고    scopus 로고
    • Dangerous liaisons at the virological synapse
    • Piguet V, Sattentau Q. Dangerous liaisons at the virological synapse. J Clin Invest 2004; 114:605-610.
    • (2004) J Clin Invest , vol.114 , pp. 605-610
    • Piguet, V.1    Sattentau, Q.2
  • 19
    • 33847197497 scopus 로고    scopus 로고
    • Dendritic cell-mediated transenhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN
    • Boggiano C, Manel N, Littman DR. Dendritic cell-mediated transenhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN. J Virol 2007; 81:2519-2523.
    • (2007) J Virol , vol.81 , pp. 2519-2523
    • Boggiano, C.1    Manel, N.2    Littman, D.R.3
  • 20
    • 37649009793 scopus 로고    scopus 로고
    • Syndecan-3 is a dendritic cellspecific attachment receptor for HIV-1
    • de Witte L, Bobardt M, Chatterji U, et al. Syndecan-3 is a dendritic cellspecific attachment receptor for HIV-1. Proc Natl Acad Sci U S A 2007; 104:19464-19469.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19464-19469
    • de Witte, L.1    Bobardt, M.2    Chatterji, U.3
  • 21
    • 33847149747 scopus 로고    scopus 로고
    • Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells
    • Smith AL, Ganesh L, Leung K, et al. Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. J Exp Med 2007; 204:421-430.
    • (2007) J Exp Med , vol.204 , pp. 421-430
    • Smith, A.L.1    Ganesh, L.2    Leung, K.3
  • 22
    • 34249088361 scopus 로고    scopus 로고
    • Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication
    • Hodges A, Sharrocks K, Edelmann M, et al. Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. Nat Immunol 2007; 8:569-577.
    • (2007) Nat Immunol , vol.8 , pp. 569-577
    • Hodges, A.1    Sharrocks, K.2    Edelmann, M.3
  • 23
    • 34248544993 scopus 로고    scopus 로고
    • C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB
    • Gringhuis SI, den Dunnen J, Litjens M, et al. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. Immunity 2007; 26:605-616.
    • (2007) Immunity , vol.26 , pp. 605-616
    • Gringhuis, S.I.1    den Dunnen, J.2    Litjens, M.3
  • 24
    • 21144438323 scopus 로고    scopus 로고
    • HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse
    • Garcia E, Pion M, Pelchen-Matthews A, et al. HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic 2005; 6:488-501.
    • (2005) Traffic , vol.6 , pp. 488-501
    • Garcia, E.1    Pion, M.2    Pelchen-Matthews, A.3
  • 25
    • 31444453892 scopus 로고    scopus 로고
    • Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
    • Wiley RD, Gummuluru S. Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc Natl Acad Sci U S A 2006; 103:738-743.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 738-743
    • Wiley, R.D.1    Gummuluru, S.2
  • 26
    • 38149040172 scopus 로고    scopus 로고
    • HIV-1 replication in dendritic cells occurs via a tetraspanin-containing compartment enriched in AP-3
    • Garcia E, Nikolic DS, Piguet V. HIV-1 replication in dendritic cells occurs via a tetraspanin-containing compartment enriched in AP-3. Traffic 2008; 9:200-214.
    • (2008) Traffic , vol.9 , pp. 200-214
    • Garcia, E.1    Nikolic, D.S.2    Piguet, V.3
  • 27
    • 33748626539 scopus 로고    scopus 로고
    • Differential susceptibility of naive, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission
    • Groot F, van Capel TM, Schuitemaker J, et al. Differential susceptibility of naive, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission. Retrovirology 2006; 3:52.
    • (2006) Retrovirology , vol.3 , pp. 52
    • Groot, F.1    van Capel, T.M.2    Schuitemaker, J.3
  • 28
    • 33847219326 scopus 로고    scopus 로고
    • Preferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes
    • + T cells, suggesting a role of dendritic cells in R5 HIV-1 selection during parenteral transmission
    • + T cells, suggesting a role of dendritic cells in R5 HIV-1 selection during parenteral transmission.
    • (2007) J Virol , vol.81 , pp. 2297-2306
    • Cameron, P.U.1    Handley, A.J.2    Baylis, D.C.3
  • 29
    • 33847237613 scopus 로고    scopus 로고
    • Wang JH, Janas AM, Olson WJ, et al. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol 2007; 81:2497-2507. This study suggested that HIV-1 Nef enhances dendritic cell-mediated HIV-1 transmission, and that CD4 coexpression modulates DC-SIGN-mediated viral transmission.
    • Wang JH, Janas AM, Olson WJ, et al. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol 2007; 81:2497-2507. This study suggested that HIV-1 Nef enhances dendritic cell-mediated HIV-1 transmission, and that CD4 coexpression modulates DC-SIGN-mediated viral transmission.
  • 30
    • 17444371691 scopus 로고    scopus 로고
    • Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes
    • Nobile C, Petit C, Moris A, et al. Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes. J Virol 2005; 79:5386-5399.
    • (2005) J Virol , vol.79 , pp. 5386-5399
    • Nobile, C.1    Petit, C.2    Moris, A.3
  • 31
    • 32444448944 scopus 로고    scopus 로고
    • Human immunodeficiency virus fusion to dendritic cells declines as cells mature
    • Cavrois M, Neidleman J, Kreisberg JF, et al. Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol 2006; 80:1992-1999.
    • (2006) J Virol , vol.80 , pp. 1992-1999
    • Cavrois, M.1    Neidleman, J.2    Kreisberg, J.F.3
  • 32
    • 33644749292 scopus 로고    scopus 로고
    • Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells
    • Burleigh L, Lozach P-Y, Schiffer C, et al. Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells. J Virol 2006; 80:2949-2957.
    • (2006) J Virol , vol.80 , pp. 2949-2957
    • Burleigh, L.1    Lozach, P.-Y.2    Schiffer, C.3
  • 33
    • 33846258118 scopus 로고    scopus 로고
    • Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels
    • Pion M, Arrighi JF, Jiang J, et al. Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels. J Invest Dermatol 2007; 127:319-323.
    • (2007) J Invest Dermatol , vol.127 , pp. 319-323
    • Pion, M.1    Arrighi, J.F.2    Jiang, J.3
  • 34
    • 43249124385 scopus 로고    scopus 로고
    • Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry
    • Janas AM, Dong C, Wang JH, et al. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry. Virology 2008; 375:442-451.
    • (2008) Virology , vol.375 , pp. 442-451
    • Janas, A.M.1    Dong, C.2    Wang, J.H.3
  • 35
    • 1642392156 scopus 로고    scopus 로고
    • DC-SIGN promotes exogenous MHC-Irestricted HIV-1 antigen presentation
    • Moris A, Nobile C, Buseyne F, et al. DC-SIGN promotes exogenous MHC-Irestricted HIV-1 antigen presentation. Blood 2004; 103:2648-2654.
    • (2004) Blood , vol.103 , pp. 2648-2654
    • Moris, A.1    Nobile, C.2    Buseyne, F.3
  • 36
    • 33745070227 scopus 로고    scopus 로고
    • Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
    • Schindler M, Munch J, Kutsch O, et al. Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell 2006; 125:1055-1067.
    • (2006) Cell , vol.125 , pp. 1055-1067
    • Schindler, M.1    Munch, J.2    Kutsch, O.3
  • 37
    • 37049003772 scopus 로고    scopus 로고
    • Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection
    • Duvall MG, Lore K, Blaak H, et al. Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol 2007; 81:13486-13498.
    • (2007) J Virol , vol.81 , pp. 13486-13498
    • Duvall, M.G.1    Lore, K.2    Blaak, H.3
  • 38
    • 36049037370 scopus 로고    scopus 로고
    • Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses
    • This study estimated that cell-associated transfer of HIV-1 through virological synapses can be 92 to 18 600-fold more efficient than that of cell-free virus
    • Chen P, Hubner W, Spinelli MA, et al. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol 2007; 81:12582-12595. This study estimated that cell-associated transfer of HIV-1 through virological synapses can be 92 to 18 600-fold more efficient than that of cell-free virus.
    • (2007) J Virol , vol.81 , pp. 12582-12595
    • Chen, P.1    Hubner, W.2    Spinelli, M.A.3
  • 39
    • 34249823098 scopus 로고    scopus 로고
    • Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1
    • Jolly C, Mitar I, Sattentau QJ. Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1. J Virol 2007; 81:5547-5560.
    • (2007) J Virol , vol.81 , pp. 5547-5560
    • Jolly, C.1    Mitar, I.2    Sattentau, Q.J.3
  • 40
    • 37049018852 scopus 로고    scopus 로고
    • Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells
    • Jolly C, Mitar I, Sattentau QJ. Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells. J Virol 2007; 81:13916-13921.
    • (2007) J Virol , vol.81 , pp. 13916-13921
    • Jolly, C.1    Mitar, I.2    Sattentau, Q.J.3
  • 41
    • 33846472081 scopus 로고    scopus 로고
    • ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation
    • Sol-Foulon N, Sourisseau M, Porrot F, et al. ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation. EMBO J 2007; 26:516-526.
    • (2007) EMBO J , vol.26 , pp. 516-526
    • Sol-Foulon, N.1    Sourisseau, M.2    Porrot, F.3
  • 42
    • 38849168755 scopus 로고    scopus 로고
    • + T cells. The efficiency of HIV-1 transmission by nanotubes remains to be determined when compare to virological synapse-mediated viral transfer.
    • + T cells. The efficiency of HIV-1 transmission by nanotubes remains to be determined when compare to virological synapse-mediated viral transfer.
  • 43
    • 44349094889 scopus 로고    scopus 로고
    • Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses
    • Groot F, Welsch S, Sattentau QJ. Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses. Blood 2008; 111:4660-4663.
    • (2008) Blood , vol.111 , pp. 4660-4663
    • Groot, F.1    Welsch, S.2    Sattentau, Q.J.3
  • 44
    • 42949175719 scopus 로고    scopus 로고
    • + T cells through virological synapses.
    • + T cells through virological synapses.
  • 45
    • 33845493481 scopus 로고    scopus 로고
    • Plasma membrane is the site of productive HIV-1 particle assembly
    • Jouvenet N, Neil SJ, Bess C, et al. Plasma membrane is the site of productive HIV-1 particle assembly. PLoS Biol 2006; 4:e435.
    • (2006) PLoS Biol , vol.4
    • Jouvenet, N.1    Neil, S.J.2    Bess, C.3
  • 46
    • 34047225272 scopus 로고    scopus 로고
    • HIV-1 buds predominantly at the plasmamembrane of primary human macrophages
    • Welsch S, Keppler OT, Habermann A, et al. HIV-1 buds predominantly at the plasmamembrane of primary human macrophages. PLoS Pathog 2007; 3:e36.
    • (2007) PLoS Pathog , vol.3
    • Welsch, S.1    Keppler, O.T.2    Habermann, A.3
  • 47
    • 34247529467 scopus 로고    scopus 로고
    • In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53
    • Deneka M, Pelchen-Matthews A, Byland R, et al. In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. J Cell Biol 2007; 177:329-341.
    • (2007) J Cell Biol , vol.177 , pp. 329-341
    • Deneka, M.1    Pelchen-Matthews, A.2    Byland, R.3
  • 48
    • 34547687819 scopus 로고    scopus 로고
    • HIV-1 buds and accumulates in "nonacidic" endosomes of macrophages
    • An ultrastructural study suggested that HIV-1 survives within a nonacidic assembly compartment preventing intracellular degradation
    • Jouve M, Sol-Foulon N, Watson S, et al. HIV-1 buds and accumulates in "nonacidic" endosomes of macrophages. Cell Host Microbe 2007; 2:85-95. An ultrastructural study suggested that HIV-1 survives within a nonacidic assembly compartment preventing intracellular degradation.
    • (2007) Cell Host Microbe , vol.2 , pp. 85-95
    • Jouve, M.1    Sol-Foulon, N.2    Watson, S.3
  • 49
    • 33745825951 scopus 로고    scopus 로고
    • NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells
    • Savina A, Jancic C, Hugues S, et al. NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell 2006; 126:205-218.
    • (2006) Cell , vol.126 , pp. 205-218
    • Savina, A.1    Jancic, C.2    Hugues, S.3
  • 50
    • 36549082476 scopus 로고    scopus 로고
    • Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes
    • Pollicita M, Schols D, Aquaro S, et al. Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes. Virology 2008; 370:382-391.
    • (2008) Virology , vol.370 , pp. 382-391
    • Pollicita, M.1    Schols, D.2    Aquaro, S.3
  • 51
    • 34848893294 scopus 로고    scopus 로고
    • Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein
    • Swingler S, Mann AM, Zhou J, et al. Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein. PLoS Pathog 2007; 3:1281-1290.
    • (2007) PLoS Pathog , vol.3 , pp. 1281-1290
    • Swingler, S.1    Mann, A.M.2    Zhou, J.3
  • 52
    • 39749152063 scopus 로고    scopus 로고
    • Akt inhibitors as an HIV-1 infected macrophage-specific antiviral therapy
    • Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, et al. Akt inhibitors as an HIV-1 infected macrophage-specific antiviral therapy. Retrovirology 2008; 5:11.
    • (2008) Retrovirology , vol.5 , pp. 11
    • Chugh, P.1    Bradel-Tretheway, B.2    Monteiro-Filho, C.M.3
  • 53
    • 34648840539 scopus 로고    scopus 로고
    • Host factors influencing susceptibility to HIV infection and AIDS progression
    • This is a comprehensive review on host factors affecting susceptibility to HIV infection and AIDS progression
    • Lama J, Planelles V. Host factors influencing susceptibility to HIV infection and AIDS progression. Retrovirology 2007; 4:52. This is a comprehensive review on host factors affecting susceptibility to HIV infection and AIDS progression.
    • (2007) Retrovirology , vol.4 , pp. 52
    • Lama, J.1    Planelles, V.2
  • 54
    • 36849093472 scopus 로고    scopus 로고
    • Semen-derived amyloid fibrils drastically enhance HIV infection
    • This study reported that human semen-derived amyloid fibrils can enhance HIV-1 infectivity by more than 100 000-fold under the experimental conditions. The mechanisms underlying the formation of the amyloid fibrils and the enhancement of HIV-1 infectivity remain to be elucidated
    • Münch J, Rucker E, Standker L, et al. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 2007; 131:1059-1071. This study reported that human semen-derived amyloid fibrils can enhance HIV-1 infectivity by more than 100 000-fold under the experimental conditions. The mechanisms underlying the formation of the amyloid fibrils and the enhancement of HIV-1 infectivity remain to be elucidated.
    • (2007) Cell , vol.131 , pp. 1059-1071
    • Münch, J.1    Rucker, E.2    Standker, L.3
  • 55
    • 37049027132 scopus 로고    scopus 로고
    • Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN
    • Sabatté J, Ceballos A, Raiden S, et al. Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN. J Virol 2007; 81:13723-13734.
    • (2007) J Virol , vol.81 , pp. 13723-13734
    • Sabatté, J.1    Ceballos, A.2    Raiden, S.3
  • 56
    • 33748687966 scopus 로고    scopus 로고
    • Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: Transmission facilitation versus replication inhibition
    • Groot F, van Capel TM, Kapsenberg ML, et al. Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition. Blood 2006; 108:1957-1964.
    • (2006) Blood , vol.108 , pp. 1957-1964
    • Groot, F.1    van Capel, T.M.2    Kapsenberg, M.L.3
  • 57
    • 40349111591 scopus 로고    scopus 로고
    • Meyers JH, Justement JS, Hallahan CW, et al. Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLoS ONE 2007; 2:e458. A study suggested that plasmacytoid dendritic cells can be important mediators of innate anti-HIV-1 immunity.
    • Meyers JH, Justement JS, Hallahan CW, et al. Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLoS ONE 2007; 2:e458. A study suggested that plasmacytoid dendritic cells can be important mediators of innate anti-HIV-1 immunity.
  • 58
    • 33845906383 scopus 로고    scopus 로고
    • APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
    • Pion M, Granelli-Piperno A, Mangeat B, et al. APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection. J Exp Med 2006; 203:2887-2893.
    • (2006) J Exp Med , vol.203 , pp. 2887-2893
    • Pion, M.1    Granelli-Piperno, A.2    Mangeat, B.3
  • 59
    • 34347371436 scopus 로고    scopus 로고
    • Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression
    • Peng G, Greenwell-Wild T, Nares S, et al. Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression. Blood 2007; 110:393-400.
    • (2007) Blood , vol.110 , pp. 393-400
    • Peng, G.1    Greenwell-Wild, T.2    Nares, S.3
  • 60
    • 42449141206 scopus 로고    scopus 로고
    • APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells
    • Wang FX, Huang J, Zhang H, et al. APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells. J Gen Virol 2008; 89:722-730.
    • (2008) J Gen Virol , vol.89 , pp. 722-730
    • Wang, F.X.1    Huang, J.2    Zhang, H.3
  • 61
    • 33847617830 scopus 로고    scopus 로고
    • HIV-1 gp120 inhibits TLR9-mediated activation and IFN-a secretion in plasmacytoid dendritic cells
    • This study suggested that HIV-1 gp120 antagonizes the innate anti-HIV-1 activity of plasmacytoid dendritic cells
    • Martinelli E, Cicala C, Van Ryk D, et al. HIV-1 gp120 inhibits TLR9-mediated activation and IFN-a secretion in plasmacytoid dendritic cells. Proc Natl Acad Sci U S A 2007; 104:3396-3401. This study suggested that HIV-1 gp120 antagonizes the innate anti-HIV-1 activity of plasmacytoid dendritic cells.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3396-3401
    • Martinelli, E.1    Cicala, C.2    Van Ryk, D.3
  • 62
    • 34548021883 scopus 로고    scopus 로고
    • Retroviral proteins that interact with the host cell cytoskeleton
    • Naghavi MH, Goff SP. Retroviral proteins that interact with the host cell cytoskeleton. Curr Opin Immunol 2007; 19:402-407.
    • (2007) Curr Opin Immunol , vol.19 , pp. 402-407
    • Naghavi, M.H.1    Goff, S.P.2
  • 63
    • 35648969165 scopus 로고    scopus 로고
    • Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses
    • Dustin ML. Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses. Curr Opin Cell Biol 2007; 19:529-533.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 529-533
    • Dustin, M.L.1
  • 64
    • 33947591273 scopus 로고    scopus 로고
    • Modulation of the immunological synapse: A key to HIV-1 pathogenesis?
    • Fackler OT, Alcover A, Schwartz O. Modulation of the immunological synapse: a key to HIV-1 pathogenesis? Nat Rev Immunol 2007; 7:310-317.
    • (2007) Nat Rev Immunol , vol.7 , pp. 310-317
    • Fackler, O.T.1    Alcover, A.2    Schwartz, O.3
  • 65
    • 33646552033 scopus 로고    scopus 로고
    • Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
    • Thoulouze MI, Sol-Foulon N, Blanchet F, et al. Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse. Immunity 2006; 24:547-561.
    • (2006) Immunity , vol.24 , pp. 547-561
    • Thoulouze, M.I.1    Sol-Foulon, N.2    Blanchet, F.3
  • 66
    • 39349097864 scopus 로고    scopus 로고
    • Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008; 319:921-926. A new study reported over 250 cellular proteins that are required for HIV-1 replication. Despite using a HeLa-cell-derived cell line in the genomic screen, this study provided new insights into further studies of HIV-host interactions.
    • Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008; 319:921-926. A new study reported over 250 cellular proteins that are required for HIV-1 replication. Despite using a HeLa-cell-derived cell line in the genomic screen, this study provided new insights into further studies of HIV-host interactions.
  • 67
    • 38549095979 scopus 로고    scopus 로고
    • Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008; 451:425-430. A host protein termed tetherin is found to inhibit retrovirus release from the cell surface, while HIV-1 Vpu counteracts tetherin's antiviral function. Thus, inhibition of Vpu function could be a potential therapeutic strategy against HIV-1 infection
    • Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008; 451:425-430. A host protein termed tetherin is found to inhibit retrovirus release from the cell surface, while HIV-1 Vpu counteracts tetherin's antiviral function. Thus, inhibition of Vpu function could be a potential therapeutic strategy against HIV-1 infection.
  • 68
    • 41849116366 scopus 로고    scopus 로고
    • The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
    • Van Damme N, Goff D, Katsura C, et al. The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008; 3:245-252.
    • (2008) Cell Host Microbe , vol.3 , pp. 245-252
    • Van Damme, N.1    Goff, D.2    Katsura, C.3
  • 69
    • 34247877512 scopus 로고    scopus 로고
    • Mucosal dendritic cells
    • Iwasaki A. Mucosal dendritic cells. Annu Rev Immunol 2007; 25:381-418.
    • (2007) Annu Rev Immunol , vol.25 , pp. 381-418
    • Iwasaki, A.1
  • 70
    • 33748146017 scopus 로고    scopus 로고
    • Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T-cell activation, and viral transfer
    • Moris A, Pajot A, Blanchet F, et al. Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T-cell activation, and viral transfer. Blood 2006; 108:1643-1651.
    • (2006) Blood , vol.108 , pp. 1643-1651
    • Moris, A.1    Pajot, A.2    Blanchet, F.3
  • 71
    • 34447292337 scopus 로고    scopus 로고
    • Rapid MHC-II antigen presentation of HIV type 1 by human dendritic cells
    • Jones L, McDonald D, Canaday DH. Rapid MHC-II antigen presentation of HIV type 1 by human dendritic cells. AIDS Res Hum Retroviruses 2007; 23:812-816.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 812-816
    • Jones, L.1    McDonald, D.2    Canaday, D.H.3
  • 72
    • 37349066496 scopus 로고    scopus 로고
    • HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells
    • Shan M, Klasse PJ, Banerjee K, et al. HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells. PLoS Pathog 2007; 3:e169.
    • (2007) PLoS Pathog , vol.3
    • Shan, M.1    Klasse, P.J.2    Banerjee, K.3
  • 73
    • 33847372187 scopus 로고    scopus 로고
    • Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes
    • van Montfort T, Nabatov AA, Geijtenbeek TB, et al. Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes. J Immunol 2007; 178:3177-3185.
    • (2007) J Immunol , vol.178 , pp. 3177-3185
    • van Montfort, T.1    Nabatov, A.A.2    Geijtenbeek, T.B.3
  • 74
    • 34548670468 scopus 로고    scopus 로고
    • CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entryindependent mechanisms
    • This study suggested that host factors CCL3L1 and CCR5 influence viral pathogenesis through cell-mediated immunity and viral entry-independent mechanisms
    • Dolan MJ, Kulkarni H, Camargo JF, et al. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entryindependent mechanisms. Nat Immunol 2007; 8:1324-1336. This study suggested that host factors CCL3L1 and CCR5 influence viral pathogenesis through cell-mediated immunity and viral entry-independent mechanisms.
    • (2007) Nat Immunol , vol.8 , pp. 1324-1336
    • Dolan, M.J.1    Kulkarni, H.2    Camargo, J.F.3
  • 75
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3
  • 76
    • 39449098115 scopus 로고    scopus 로고
    • HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells
    • + T cells via HIV-1 gp120 activates or leukocyte function-associated antigen-1, which facilitates VSmediated cell-cell transmission of HIV-1
    • + T cells via HIV-1 gp120 activates or leukocyte function-associated antigen-1, which facilitates VSmediated cell-cell transmission of HIV-1.
    • (2008) Nat Immunol , vol.9 , pp. 301-309
    • Arthos, J.1    Cicala, C.2    Martinelli, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.