Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes

Virology

Volumn 370, Issue 2, 2008, Pages 382-391

  Pollicita, M ^a   Schols, D ^b   Aquaro, S ^a,c   Peumans, W J ^d   Van Damme, E J M ^d   Perno, C F ^a   Balzarini, J ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF CALABRIA   (Italy)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Carbohydrate binding agents (CBAs); DC SIGN; Envelope glycoprotein gp120; Glycans; HIV 1; HIV 1 capture; HIV 1 transmission; Macrophage mannose binding receptor (MMR); Monocyte derived macrophages (MDMs)

Indexed keywords

ANTIVIRUS AGENT; CARBOHYDRATE BINDING AGENT; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; MICROBICIDE; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONOCYTE DERIVED MACROPHAGE; PRIORITY JOURNAL; RECEPTOR BINDING; T LYMPHOCYTE; VIRUS STRAIN; VIRUS TRANSMISSION;

ANTI-HIV AGENTS; CARBOHYDRATE METABOLISM; CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; HIV-1; HUMANS; LECTINS, C-TYPE; MACROPHAGES; MANNOSE-BINDING LECTINS; MICROBIAL SENSITIVITY TESTS; PLANT LECTINS; RECEPTORS, CELL SURFACE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 36549082476     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.08.033     Document Type: Article

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