Using liquid chromatography-ion trap mass spectrometry to determine pharmaceutical residues in Taiwanese rivers and wastewaters

Chemosphere

Volumn 72, Issue 6, 2008, Pages 863-869

  Chen, Hsin Chang ^a   Wang, Pi Lien ^a   Ding, Wang Hsien ^a  

^a NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

Electrospray ionization; Liquid chromatography tandem mass spectrometry; Pharmaceutical residues; Water analysis

Indexed keywords

CONCENTRATION (PROCESS); DRUG PRODUCTS; ELECTROSPRAY IONIZATION; EXTRACTION;

LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; PHARMACEUTICAL RESIDUES;

WATER ANALYSIS;

CARBAMAZEPINE; CLOFIBRIC ACID; DICLOFENAC; DRUG RESIDUE; IBUPROFEN; KETOPROFEN;

CONCENTRATION (PROCESS); DRUG PRODUCTS; ELECTROSPRAY IONIZATION; EXTRACTION; WATER ANALYSIS;

DRUG; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RIVER WATER; WASTEWATER; WATER TREATMENT;

ACCURACY; ARTICLE; CHEMICAL WASTE; EFFLUENT; ELECTROSPRAY; HOSPITAL WASTE; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; QUANTITATIVE ANALYSIS; RIVER; SOLID PHASE EXTRACTION; TAIWAN; WASTE COMPONENT REMOVAL; WASTE WATER; WATER SAMPLING;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENVIRONMENTAL MONITORING; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; RIVERS; SENSITIVITY AND SPECIFICITY; TAIWAN; WATER POLLUTANTS, CHEMICAL;

ASIA; EURASIA; FAR EAST; TAIWAN;

EID: 53949125196     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.04.005     Document Type: Article

References (49)

1. Al-Rifai J.H., Gabelish C.L., and Schäfer A.I. Occurrence of pharmaceutically active and non-steroidal estrogenic compounds in three different wastewater recycling schemes in Australia. Chemosphere 69 (2007) 803-815
2. Brown J.N., Paxéus N., Förlin L., and Joakim Larsson D.G. Variations in bioconcentration of human pharmaceuticals from sewage effluents into fish blood plasma. Environ. Toxicol. Pharma 24 (2007) 267-274
3. Castiglioni S., Bagnati R., Calamari D., Fanelli R., and Zuccato E. A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography-tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters. J. Chromatogr. A 1092 (2005) 206-215
4. Clara M., Strenn B., Gans O., Martinez E., Kreuzinger N., and Kroiss H. Removal of selected pharmaceuticals, fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants. Water Res. 39 (2005) 4797-4807
5. Daughton C.G., and Ternes T.A. Pharmaceuticals and personal care products in the environment: agents of subtle change?. Environ. Health Persp. 107 (1999) 907-937
6. de Alda M.J.L., Diaz-Cruz S., Petrović M., and Barceló D. Liquid chromatography-(tandem) mass spectrometry of selected emerging pollutants (steroid sex hormones, drugs and alkylphenolic surfactants) in the aquatic environment. J. Chromatogr. A 1000 (2003) 503-526
7. Enick O.V., and Moore M.M. Assessing the assessments: pharmaceuticals in the environment. Environ. Impact Assess. Rev. 27 (2007) 707-729
8. Farré M.-L., Ferrer I., Ginebreda A., Figueras M., Olivella L., Tirapu L., Vilanova M., and Barceló D. Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: methods and preliminary results including toxicity studies with Vibrio fischeri. J. Chromatogr. A 938 (2001) 187-197
9. Fatta D., Nikolaou A., Achilleos A., and Meriç S. Analytical methods for tracing pharmaceutical residues in water and wastewater. Trends Anal. Chem. 26 (2007) 515-533
10. Gómez M.J., Petrović M., Fernández-Alba A.R., and Barceló D. Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters. J. Chromatogr. A 1114 (2006) 224-233
11. Gómez M.J., Martínez Bueno M.J., Lacorte S., Fernández-Alba A.R., and Agüera A. Pilot survey monitoring pharmaceuticals and related compounds in a sewage treatment plant located on the Mediterranean coast. Chemosphere 66 (2007) 993-1002
12. Gros M., Petrović M., and Barceló D. Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters. Talanta 70 (2006) 678-690
13. Haiß A., and Kümmerer K. Biodegradability of the X-ray contrast compound diatrizoic acid, identification of aerobic degradation products and effects against sewage sludge micro-organisms. Chemosphere 62 (2006) 294-302
14. Heberer T. Tracking persistent pharmaceutical residues from municipal sewage to drinking water. J. Hydrol. 266 (2002) 175-189
15. Hilton M.J., and Thomas K.V. Determination of selected human pharmaceuticals compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 1015 (2003) 129-141
16. Kasprzyk-Hordern B., Dinsdale R.M., and Guwy A.J. Multi-residue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry. J. Chromatogr. A 1161 (2007) 132-145
17. Kim S.D., Cho J., Kim I.S., Vanderford B.J., and Snyder S.A. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res. 41 (2007) 1013-1021
18. Kimura K., Hara H., and Watanabe Y. Elimination of selected acidic pharmaceuticals from municipal wastewater by an activated sludge system and membrane bioreactors. Environ. Sci. Technol. 41 (2007) 3708-3714
19. Kloepfer A., Quintana J.B., and Reemtsma T. Operational options to reduce matrix effects in liquid chromatography-electrospray ionisation-mass spectrometry analysis of aqueous environmental samples. J. Chromatogr. A 1067 (2005) 153-160
20. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., and Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 36 (2002) 1202-1211
21. In: Kümmerer K. (Ed). Pharmaceuticals in the Environment. second ed. Sources, Fate, Effects and Risks (2004), Springer-Verlag, New York
22. Lin A.Y.C., and Reinhard M. Photodegradation of common environmental pharmaceuticals and estrogens in river water. Environ. Toxicol. Chem. 24 (2005) 1303-1309
23. Lin W.C., Chen H.C., and Ding W.H. Determination of pharmaceutical resides in waters by solid-phase extraction and large-volume on-line derivatization with gas chromatography-mass spectrometry. J. Chromatogr. A 1065 (2005) 279-285
24. Moldovan Z. Occurrences of pharmaceutical and personal care products as micropollutants in rivers from Romania. Chemosphere 64 (2006) 1808-1817
25. Öllers S., Singer H.P., Fässler P., and Müller R.S. Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water. J. Chromatogr. A 911 (2001) 225-234
26. Pedersen J.A., Yeager M.A., and Suffet I.H. Xenobiotic organic compounds in runoff from fields irrigated with treated wastewater. J. Agric. Food Chem. 51 (2003) 1360-1372
27. Pedersen J.A., Soliman M., and Suffet I.H. Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. J. Agric. Food Chem. 53 (2005) 1625-1632
28. Petrović M., Hernando M.D., Diaz-Cruz M.S., and Barceló D. Liquid chromatography-tandem mass spectrometry for the analysis of pharmaceutical residues in environmental samples: a review. J. Chromatogr. A 1067 (2005) 1-14
29. Petrović M., Gros M., and Barceló D. Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. J. Chromatogr. A 1124 (2006) 68-81
30. Quintana J.B., Rodil R., Muniategui-Lorenzo S., López-Mahía P., and Prada-Rodríguez D. Multiresidue analysis of acidic and polar organic contaminants in water samples by stir-bar sorptive extraction-liquid desorption-gas chromatography-mass spectrometry. J. Chromatogr. A. 1174 (2007) 27-39
31. Quinn B., Gagné F., and Blaise C. An investigation into the acute and chronic toxicity of eleven pharmaceuticals (and their solvents) found in wastewater effluent on the cnidarian, Hydra attenuate. Sci. Total Environ. 389 (2008) 306-314
32. Reza Anari M., Bakhtiar R., Zhu B., Huskey S., Franklin R.B., and Evans D.C. Derivatization of ethinylestradiol with dansyl chloride to enhance electrospray ionization: application in trace analysis of ethinylestradiol in rhesus monkey plasma. Anal. Chem. 74 (2002) 4136-4144
33. Sarmah A.K., Meyer M.T., and Boxall A.B.A. A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 65 (2006) 725-759
34. SciFinder Scholar, 2006. The Values Calculated Using Advanced Chemistry Development (ACD) Software Solaris. American Chemical Society, Washington, DC, 2006.
35. Stolker A.A.M., Niesing W., Fuchs R., Vreeken R.J., Niessen W.M.A., and Brinkman U.A.Th. Liquid chromatography with triple-quadrupole and quadrupole-time-of-flight mass spectrometry for the determination of micro-constituents - a comparison. Anal. Bioanal. Chem. 378 (2004) 1754-1761
36. Ternes T.A. Occurrence of drugs in German sewage treatment plants and rivers. Water Res. 32 (1998) 3245-3260
37. Tixier C., Singer H.P., Oellers S., and Müller S.R. Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. Environ. Sci. Technol. 37 (2003) 1061-1068
38. Togola A., and Budzinski H. Multi-residue analysis of pharmaceutical compounds in aqueous samples. J. Chromatogr. A 1177 (2008) 150-158
39. Trenholm R.A., Vanderford B.J., Holady J.C., Rexing D.J., and Snyder S.A. Broad range analysis of endocrine disruptors and pharmaceuticals using gas chromatography and liquid chromatography-tandem mass spectrometry. Chemosphere 65 (2006) 1990-1998
40. Vanderford B.J., Pearson R.A., Rexing D.J., and Snyder S.A. Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry. Anal. Chem. 75 (2003) 6265-6274
41. Verenitch S.S., Lowe C.J., and Mazumder A. Determination of acidic drugs and caffeine in municipal wastewaters and receiving waters by gas chromatography-ion trap tandem mass spectrometry. J. Chromatogr. A 1116 (2006) 193-203
42. Vieno N.M., Tuhkanen T., and Kronberg L. Seasonal variation in the occurrence of pharmaceuticals in effluents from a sewage treatment plant and in the recipient water. Environ. Sci. Technol. 39 (2005) 8220-8226
43. Vieno N.M., Tuhkanen T., and Kronberg L. Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection. J. Chromatogr. A 1134 (2006) 101-111
44. Vieno N.M., Härkki H., Tuhkanen T., and Kronberg L. Occurrence of pharmaceuticals in river water and their elimination in a pilot-scale drinking water treatment plant. Environ. Sci. Technol. 41 (2007) 5077-5084
45. Westerhoff P., Yoon Y.M., Snyder S., and Wert E. Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes. Environ. Sci. Technol. 39 (2005) 6649-6663
46. Williams M., Saison C.L.A., Williams D.B., and Kookana R.S. Can aquatic distribution of human pharmaceuticals be related to pharmacological data?. Chemosphere 65 (2006) 2253-2259
47. Yu Z., Peldszus S., and Huck P.M. Optimizing gas chromatographic-mass spectrometric analysis of selected pharmaceuticals and endocrine-disrupting substances in water using factorial experimental design. J. Chromatogr. A 1148 (2007) 65-77
48. Zhang S., Zhang Q., Darisaw S., Ehie O., and Wang G. Simultaneous quantification of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and pharmaceuticals and personal care products (PPCPs) in Mississippi river water, in New Orleans, Louisiana, USA. Chemosphere 66 (2007) 1057-1069
49. Zuehlke S., Duennbier U., and Heberer T. Determination of polar drug residues in sewage and surface water applying liquid chromatography-tandem mass spectrometry. Anal. Chem. 76 (2004) 6548-6655