Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes

Environmental Science and Technology

Volumn 39, Issue 17, 2005, Pages 6649-6663

  Westerhoff, Paul ^a   Yoon, Yeomin ^b   Snyder, Shane ^c   Wert, Eric ^c  

^a Arizona State University   (United States)

^b Northwestern University   (United States)

^c SOUTHERN NEVADA WATER AUTHORITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; HERBICIDES; IMPURITIES; OXIDATION; OZONE; PESTICIDES; PH EFFECTS; POTABLE WATER; REMOVAL; WATER TREATMENT; WATER TREATMENT PLANTS;

DRINKING WATER SUPPLY; ENDOCRINE DISRUPTOR; PERSONAL CARE PRODUCTS (PPCP); WATER TREATMENT PROCESSES;

ORGANIC COMPOUNDS;

ACTIVATED CARBON; ALUMINUM SULFATE; ANDROSTENEDIONE; CHLORDANE; CHLORINE; DIELDRIN; DRINKING WATER; ESTRADIOL; ESTRONE; ETHINYLESTRADIOL; FERRIC CHLORIDE; HEPTACHLOR; OZONE; POLYCYCLIC AROMATIC HYDROCARBON; PROGESTERONE; STEROID; TESTOSTERONE;

DRINKING WATER; POLLUTANT; WATER TREATMENT;

ARTICLE; CHLORINATION; EXPERIMENTATION; HYGIENE; OZONATION; PARTITION COEFFICIENT; PHASE SEPARATION; PREDICTION; PROTON TRANSPORT; SIMULATION; WATER TREATMENT;

ALUM COMPOUNDS; CALCIUM COMPOUNDS; CHARCOAL; COAGULANTS; ENDOCRINE DISRUPTORS; ENVIRONMENTAL MONITORING; FERRIC COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HETEROCYCLIC COMPOUNDS; HYDROCARBONS, AROMATIC; HYDROGEN-ION CONCENTRATION; NITROGEN; OXIDES; OZONE; PHARMACEUTICAL PREPARATIONS; PHENOLS; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION; WATER SUPPLY;

EID: 24644507816     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es0484799     Document Type: Article

References (74)

1. Kolpin, D. W.; Furlong, E. T.; Meyer, M. T.; Thurman, E. M.; Zaugg, S. D.; Barber, L. B.; Buxton, H. T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A national reconnaissance. Environ. Sci. Technol. 2002, 36, 1202-1211.
2. Ternes, T. A. Occurrence of drugs in German sewage treatment plants and rivers. Water Res. 1998, 32, 3245-3260.
3. Snyder, S. A.; Westerhoff, P.; Yoon, Y.; Sedlak, D. L. Pharmaceuticals, personal care products, and endocrine disrupters in water: Implications for water treatment. Environ. Eng. Sci. 2003, 20, 449-469.
4. Daughton, C. H.; Ternes, T. A. Special Report: Pharmaceuticals and personal care products in the environment: Agents of subtle change? (Vol. 107, p 907, 1999), Environ. Health Perspect. 2000, 108, 598-598.
5. Ongerth, J. E.; Khan, S. Drug Residuals: How xenobiotics can affect water supply sources. J.-Am. Water Works Assoc. 2004, 96, 94-101.
6. Weyer, P.; Riley, D. Endocrine Disrupters and Pharmaceuticals in Drinking Water; Awwa Research Foundation: Denver, CO, 2001.
7. Warren, R.; Walker, B.; Nathan, V. R. Environmental factors influencing public health and medicine: Policy implications. J. Natl. Med. Assoc. 2002, 94, 185-193.
8. Foster, P. M. D.; McIntyre, B. S. Endocrine active agents: Implications of adverse and nonadverse changes. Toxicol. Pathol. 2002, 30, 59-65.
9. Mantovani, A.; Macri, A. Endocrine effects in the hazard assessment of drugs used in animal production. J. Exp. Clin. Cancer Res. 2002, 21, 445-456.
10. Ankley, G.; Mihaich, E.; Stahl, R.; Tillitt, D.; Colborn, T.; McMaster, S.; Miller, R.; Bantle, J.; Campbell, P.; Denslow, N.; Dickerson, R.; Folmar, L.; Fry, M.; Giesy, J.; Gray, L. E.; Guiney, P.; Hutchinson, T.; Kennedy, S.; Kramer, V.; LeBlanc, G.; Mayes, M.; Nimrod, A.; Patino, R.; Peterson, R.; Purdy, R.; Ringer, R.; Thomas, P.; Touart, L.; Van der Kraak, G.; Zacharewski, T. Overview of a workshop on screening methods for detecting potential (anti-) estrogenic/androgenic chemicals in wildlife. Environ. Toxicol. Chem. 1998, 17, 68-87.
11. Daston, G. P.; Cook, J. C.; Kavlock, R. J. Uncertainties for endocrine disrupters: Our view on progress. Toxicol. Sci. 2003, 74, 245-252.
12. Snyder, S. A.; Vanderford, B. J.; Pearson, R. A.; Quinones, O.; Yoon, Y. Analytical methods used to measure endocrine disrupting compounds in water. Pract. Periodical Hazard., Toxic, Radioact. Waste Manage. 2003, 7, 224-234.
13. Zhang, T. C.; Emary, S. C. Jar tests for evaluation of atrazine removal at drinking water treatment plants. Environ. Eng. Sci. 1999, 16, 417-432.
14. Adams, C.; Wang, Y.; Loftin, K.; Meyer, M. Removal of antibiotics from surface and distilled water in conventional water treatment processes. J. Environ. Eng.-ASCE 2002, 128, 253-260.
15. Petrovic, M.; Eljarrat, E.; de Alda, M. J. L.; Barcelo, D. Analysis and environmental levels of endocrine-disrupting compounds in freshwater sediments. Trac-Trends Anal. Chem. 2001, 20, 637-648.
16. Ternes, T. A.; Meisenheimer, M.; McDowell, D.; Sacher, F.; Brauch, H. J.; Guide, B. H.; Preuss, G.; Wilme, U.; Seibert, N. Z. Removal of pharmaceuticals during drinking water treatment. Environ. Sci. Technol. 2002, 36, 3855-3863.
17. Alum, A.; Yoon, Y.; Westerhoff, P.; Abbaszadegan, M. Oxidation of bisphenol A, 17B-estradiol, and 17a-ethynyl estradiol and byproduct estrogenicity. Environ. Toxicol. 2004, 19, 257-264.
18. Hu, J. Y.; Aizawa, T.; Ookubo, S. Products of aqueous chlorination of bisphenol A and their estrogenic activity. Environ. Sci. Technol. 2002, 36, 1980-1987.
19. Hu, J. Y.; Cheng, S. J.; Aizawa, T.; Terao, Y.; Kunikane, S. Products of aqueous chlorination of 17 beta-estradiol and their estrogenic activities. Environ. Sci. Technol. 2003, 37, 5665-5670.
20. Huber, M.; Canonica, S.; von Gunten, U. Oxidative treatment of pharmaceuticals in drinking waters, AWWA EDC Workshop, Cincinnati, OH, 2002.
21. Huber, M. M.; Canonica, S.; Park, G. Y; Von Gunten, U. Oxidation of pharmaceuticals during ozonation and advanced oxidation processes. Environ. Sci. Technol. 2003, 37, 1016-1024.
22. Lee, B. C.; Kamata, M.; Akatsuka, Y; Takeda, M.; Ohno, K.; Kamei, T.; Magara, Y. Effects of chlorine on the decrease of estrogenic chemicals. Water Res. 2004, 38, 733-739.
23. Lopez, A.; Mascolo, G.; Tiravanti, G.; Passino, R. Degradation of herbicides (ametryn and isoproturon) during water disinfection by means of two oxidants (hypochlorite and chlorine dioxide). Water Sci. Technol. 1997, 35, 129-136.
24. Pinkston, K. E.; Sedlak, D. L. Transformation of aromatic ether and amine containing pharmaceuticals during chlorine disinfection. Environ. Sci. Technol. 2004, 38, 4019-4025.
25. von Gunten, U. Ozonation of drinking water: Part I. Oxidation kinetics and product formation. Water Res. 2003, 37, 1443-1467.
26. Zwiener, C.; Frimmel, F. H. Oxidative treatment of pharmaceuticals in water. Water Res. 2000, 34, 1881-1885.
27. Huber, M. M.; Ternes, T. A.; von Gunten, U. Removal of estrogenic activity and formation of oxidation products during ozonation of 17 alpha-ethinylestradiol. Environ. Sci. Technol. 2004, 38, 5177-5186.
28. Beltran, F. J.; Garcia-Araya, J. F.; Acedo, B. Advanced oxidation of atrazine in water. 1. Ozonation. Water Res. 1994, 28, 2153-2164.
29. Beltran, F. J.; Garcia-Araya, J. F.; Rivas, J.; Alvarez, P. M.; Rodriguez, E. Kinetics of simazine advanced oxidation in water. J. Environ. Sci. Health, Part B 2000, 35, 439-454.
30. Gould, J. P.; Richards, J. T. The kinetics and products of the chlorination of caffeine in aqueous-solution. Water Res. 1984, 18, 1001-1009.
31. Eldib, M. A.; Aly, O. A. Removal of phenylamide pesticides from drinking waters. 1. Effect of chemical coagulation and oxidants. Water Res. 1977, 11, 611-616.
32. Montiel, A.; Welte, B. Alternative options for atrazine-Incidence on water-treatment device. Water Sci. Technol. 1992, 25, 103-110.
33. Crittenden, J. C.; Sanongraj, S.; Bulloch, J. L.; Hand, D. W.; Rogers, T. N.; Speth, T. F.; Ulmer, M. Correlation of aqueous-phase adsorption isotherms. Environ. Sci. Technol. 1999, 33, 2926-2933.
34. Bruce, D.; Westerhoff, P.; Brawley-Chesworth, A. Removal of 2-methylisoborneol and geosmin in surface water treatment plants in Arizona. J. Water Supply Res. Technol.-AQUA 2002, 51, 183-197.
35. Dosoretz, C. G.; Boddeker, K. W. Removal of trace organics from water using a pumped bed-membrane bioreactor with powdered activated carbon. J. Membr. Sci. 2004, 239, 81-90.
36. Herzberg, M.; Dosoretz, C. G.; Tarre, S.; Michael, B.; Dror, M.; Green, M. Simultaneous removal of atrazine and nitrate using a biological granulated activated carbon (BGAC) reactor. J. Chem. Technol. Biotechnol. 2004, 79, 626-631.
37. Qi, S. Y.; Adham, S. S.; Snoeyink, V. L.; Lykins, B. W. Prediction and verification of atrazine adsorption by PAC. J. Environ. Eng. - ASCE 1994, 120, 202-218.
38. Boyd, G. R.; Reemtsma, H.; Grimm, D. A.; Mitra, S. Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA, and Ontario, Canada. Sci. Total Environ. 2003, 311, 135-149.
39. von Gunten, U. Ozonation of drinking water: Part II. Disinfection and byproduct formation in the presence of bromide, iodide or chlorine. Water Res. 2003, 37, 1469-1487.
40. Gallard, H.; Von Gunten, U. Chlorination of phenols: Kinetics and formation of chloroform. Environ. Sci. Technol. 2002, 36, 884-890.
41. Faust, B. C.; Hoigne, J. Sensitized photooxidation of phenols by fulvic-acid and in natural-waters. Environ. Sci. Technol. 1987, 21, 957-964.
42. Acero, J. L.; Von Gunten, U. Characterization of oxidation processes: Ozonation and the AOP O-3/H2O2. J.-Am. Water Works Assoc. 2001, 93, 90-100.
43. Huang, C. H.; Sedlak, D. Analysis of estrogenic hormones in wastewater and surface water using ELISA and GC/MS/MS. Abstr. Pap. Am. Chem. Soc. 2000, 219, 5-ENVR.
44. Carlile, P.; Fielding, M.; Harding, L; Hart, J.; Hutchison, J.; Kanda, R. Effect of water treatment processes on oestrogenic chemicals, UK WIR Report 96/DW/05/01, 1996.
45. Ternes, T. A.; Stuber, J.; Herrmann, N.; McDowell, D.; Ried, A.; Kampmann, M.; Teiser, B. Ozonation: A tool for removal of pharmaceuticals, contrast media and musk fragrances from wastewater? Water Res. 2003, 37, 1976-1982.
46. Sacher, F.; Haist-Gulde, B.; Brauch, H.; Preub, G.; Wilme, U.; Zullei-Seibert, N.; Meisenheimer, M.; Welsch, H.; Ternes, T. Behavior of selected pharmaceuticals during drinking water treatment. American Chemical Society Meeting, San Francisco, March, 2000.
47. Carlson, K. Presented at the Endocrine Disruptors and Pharmaceutically Active Chemicals in Drinking Water Workshop, Chicago, IL, 2000.
48. Haag, W. R.; Yao, C. C. D. Rate constants for reaction of hydroxyl radicals with several drinking-water contaminants. Environ. Sci. Technol. 1992, 26, 1005-1013.
49. Buxton, G. V.; Greenstock, C. L.; Helman, W. P.; Ross, A. B. Critical review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (•OH/•OH-) in aqueous solution. J. Phys. Ref. Data 1988, 17, 513-851.
50. Acero, J. L.; Stemmler, K.; Von Gunten, U. Degradation kinetics of atrazine and its degradation products with ozone and OH radicals: A predictive tool for drinking water treatment. Environ. Sci. Technol. 2000, 34, 591-597.
51. Vanderford, B. J.; Pearson, R. A.; Rexing, D. J.; Snyder, S. A. Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry. Anal. Chem. 2003, 75, 6265-6274.
52. Ahrer, W.; Scherwenk, E.; Buchberger, W. Determination of drug residues in water by the combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry. J. Chromatogr., A 2001, 910, 69-78.
53. USEPA, Enhanced Coagulation and Enhanced Precipitative Softening Guidance Manual (EPA 815-R-99-012), Washington, DC, 1999.
54. USEPA, Interim Enhanced Surface Water Treatment Rule (EPA 815-F-98-009), Washington, DC, 1998.
55. Chao, P.; Westerhoff, P. Assessment and optimization of chemical and physicochemical softening processes. J.-Am. Water Works Assoc. 2002, 94, 109-119.
56. Yoon, Y.; Westerhoff, P.; Snyder, S.; Esparza, M. HPLC-fluorescence detection and adsorption of bisphenol A, 17b-estradiol, and 17a-ethynyl estradiol on powdered activated carbon. Water Res. 2003, 37, 3530-3537.
57. Trenholm, R.; Snyder, S.; Vanderford, B. Gas Chromatographic analysis of endocrine disrupting compounds. Anal. Chem., submitted.
58. Westerhoff, P.; Song, R. G.; Amy, G.; Minear, R. NOM's role in bromine and bromate formation during ozonation. J.-Am. Water Works Assoc. 1998, 90, 82-94.
59. Westerhoff, P.; Aiken, G.; Amy, G.; Debroux, J. Relationships between the structure of natural organic matter and its reactivity towards molecular ozone and hydroxyl radicals. Water Res. 1999, 33, 2265-2276.
60. Werner, S. L.; Burkhardt, M. R.; DeRusseau, S. N. Methods of Analysis by the U.S. Geological Survey National Water Quality Laboratory: Determination of Pesticides in a Water by CarboPak-B Solid-Phase Extraction and High Performance Liquid Chromatography; U.S. Geological Survey: Reston, VA, 1996.
61. Snyder, S. A.; Leising, J.; Westerhoff, P.; Yoon, Y.; Mash, H.; Vanderford, B. Biological attenuation of EDCs and PPCPs: Implications for water reuse. Groundwater Monitor. Remed. 2004, 24, 108-118.
62. Knappe, D. R. U.; Matsui, Y.; Snoeyink, V. L.; Roche, P.; Prados, M. J.; Bourbigot, M. M. Predicting the capacity of powdered activated carbon for trace organic compounds in natural waters. Environ. Sci. Technol. 1998, 32, 1694-1698.
63. Graham, M. R.; Summers, R. S.; Simpson, M. R.; MacLeod, B. W. Modeling equilibrium adsorption of 2-methylisoborneol and geosmin in natural waters. Water Res. 2000, 34, 2291-2300.
64. Najm, I. N.; Snoeyink, V. L.; Richard, Y. Effect of initial concentration of a soc in natural-water on its adsorption by activated carbon. J.-Am. Water Works Assoc. 1991, 83, 57-63.
65. Blum, D. J. W.; Suffet, I. H.; Duguet, J. P. Quantitative structure-activity relationship using molecular connectivity for the activated carbon adsorption of organic chemicals in water. Water Res. 1994, 28, 687-699.
66. Luehrs, D. C.; Hickey, J. P.; Nilsen, P. E.; Godbole, K. A.; Rogers, T. N. Linear solvation energy relationship of the limiting partition coefficient of organic solutes between water and activated carbon. Environ. Sci. Technol. 1996, 30, 143-152.
67. OW) data for hydrophobic organic compounds: DDT and DDE as a case study, U.S. Geological Survey, Water-Resources Investigations Report 01-4201, 2001.
68. OW controversy. Environ. Sci. Technol. 2002, 411, A-413 A.
69. Summers, R. S.; Hooper, S. M.; Shukairy, H. M.; Solarik, G.; Owen, D. Assessing the DBP yield: Uniform formation conditions. J.-Am. Water Works Assoc. 1996, 88, 80-93.
70. Westerhoff, P.; Chao, P. F.; Mash, H. Reactivity of natural organic matter with aqueous chlorine and bromine. Water Res. 2004, 38, 1502-1513.
71. Ravacha, C.; Blits, R. The different reaction-mechanisms by which chlorine and chlorine dioxide react with polycyclic aromatic-hydrocarbons (PAH) in water. Water Res. 1985, 19, 1273-1281.
72. SPARC On-Line Calculator (http://ibmlc2.chem.uga.edu/sparc/), 2005.
73. USEPA Handbook for Non-Cancer Health Effects Valuation by EPA Science Policy Council Non-Cancer. Health Effects Valuation Subcommittee of the EPA Social Science Discussion Group; USEPA: Washington, DC, 2000.
74. Snyder, S. A.; Villeneuve, D. L.; Snyder, E. M.; Giesy, J. P. Identification and quantification of estrogen receptor agonists in wastewater effluents. Environ. Sci. Technol. 2001, 35, 3620-3625.