Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABAA receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 21, 2008, Pages 5713-5716

  Nilsson, Jakob ^a   Nielsen, Elsebet Østergaard ^b   Liljefors, Tommy ^c   Nielsen, Mogens ^c   Sterner, Olov ^a  

^a LUND UNIVERSITY   (Sweden)

^b NEUROSEARCH A S   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Azaflavone GABAA benzodiazepine binding site; Flavone

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1BETA3GAMMA2S; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2BETA3GAMMA2S; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA5BETA3GAMMA2S; AZAFLAVONE DERIVATIVE; FLAVONE DERIVATIVE; LIGAND; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; NONHUMAN; RAT; RECEPTOR AFFINITY;

ANIMALS; AZA COMPOUNDS; BENZODIAZEPINES; BINDING SITES; BRAIN; CELL LINE; FLAVONES; HUMANS; LIGANDS; RATS; RECEPTORS, GABA-A;

EID: 53949112240     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.092     Document Type: Article

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