Identification of ezrin as a target of gastrin in immature mouse gastric parietal cells

Experimental Physiology

Volumn 93, Issue 11, 2008, Pages 1174-1189

  Pagliocca, Adelina ^a   Hegyi, Peter ^b   Venglovecz, Viktoria ^b   Rackstraw, Stephen A ^a   Khan, Zara ^a   Burdyga, Galina ^a   Wang, Timothy C ^c   Dimaline, Rod ^a   Varro, Andrea ^a   Dockray, Graham J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF SZEGED   (Hungary)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBACHOL; CHOLECYSTOKININ B RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EZRIN; GASTRIN; HISTAMINE; MESSENGER RNA; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL PH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; HORMONE BLOOD LEVEL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; STOMACH GLAND; STOMACH PARIETAL CELL;

EID: 53949096355     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2008.042648     Document Type: Article

References (59)

1. Agnew BJ, Duman JG, Watson CL, Coling DE & Forte JG (1999). Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade. J Cell Sci 112, 2639 2646.
2. Aihara T, Fujishita T, Kanatani K, Furutani K, Nakamura E, Taketo MM, Matsui M, Chen D & Okabe S (2003). Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice. Gastroenterology 125, 1774 1784.
3. Beltinger J, Hildebrand P, Drewe J, Christ A, Hlobil K, Ritz M, D'Amato M, Rovati L & Beglinger C (1999). Effects of spiroglumide, a gastrin receptor antagonist, on acid secretion in humans. Eur J Clin Invest 29, 153 159.
4. Berglindh T, Helander H & Sachs G (1979). Secretion at the parietal cell level - a look at rabbit gastric glands. Scand J Gastroenterol Suppl 55, 7 20.
5. Berglindh T & Obrink KJ (1976). A method for preparing isolated glands from the rabbit gastric mucosa. Acta Physiol Scand 96, 150 159.
6. Black JW & Shankley NP (1987). How does gastrin act to stimulate oxyntic cell secretion. Trends Pharmacol Sci 8, 486 490.
7. Booth C, Patel S, Bennion GR & Potten CS (1995). The isolation and culture of adult mouse colonic epithelium. Epithelial Cell Biol 4, 76 86.
8. Bretscher A, Chambers D, Nguyen R & Reczek D (2000). ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu Rev Cell Dev Biol 16, 113 143.
9. Bretscher A, Edwards K & Fehon RG (2002). ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 3, 586 599.
10. Chen D, Zhao CM, Dockray GJ, Varro A, Van Hoek A, Sinclair NF, Wang TC & Koh TJ (2000). Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice. Gastroenterology 119, 756 765.
11. Chew CS (1994). Parietal cell culture: new models and directions. Annu Rev Physiol 56, 445 461.
12. 2+-independent protein kinase C isoforms may modulate parietal cell HCl secretion. Am J Physiol Gastrointest Liver Physiol 272, G246 G256.
13. Chuan YC, Pang ST, Cedazo-Minguez A, Norstedt G, Pousette A & Flores-Morales A (2006). Androgen induction of prostate cancer cell invasion is mediated by ezrin. J Biol Chem 281, 29938 29948.
14. Daulhac L, Kowalski-Chauvel A, Pradayrol L, Vaysse N & Seva C (1999). Src-family tyrosine kinases in activation of ERK-1 and p85/p110- phosphatidylinositol 3-kinase by G/CCKB receptors. J Biol Chem 274, 20657 20663.
15. i by secretagogue stimulation of canine gastric parietal cells. Am J Physiol Gastrointest Liver Physiol 262, G420 G426.
16. Dixit C & Dikshit M (2001). A flowcytometric method for evaluation of acid secretion from isolated rat gastric mucosal cells. J Pharmacol Toxicol Methods 45, 47 53.
17. Dockray G, Dimaline R & Varro A (2005). Gastrin: old hormone, new functions. Pflugers Arch 449, 344 355.
18. Dockray GJ (1999). Topical review. Gastrin and gastric epithelial physiology. J Physiol 518, 315 324.
19. Dockray GJ, Varro A & Dimaline R (1996). Gastric endocrine cells: gene expression, processing, and targeting of active products. Physiol Rev 76, 767 798.
20. Dockray GJ, Varro A, Dimaline R & Wang T (2001). The gastrins: their production and biological activities. Annu Rev Physiol 63, 119 139.
21. Dransfield DT, Bradford AJ, Smith J, Martin M, Roy C, Mangeat PH & Goldenring JR (1997). Ezrin is a cyclic AMP-dependent protein kinase anchoring protein. EMBO J 16, 35 43.
22. Dufner MM, Kirchhoff P, Remy C, Hafner P, Muller MK, Cheng SX, Tang LQ, Hebert SC, Geibel JP & Wagner CA (2005). The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands. Am J Physiol Gastrointest Liver Physiol 289, G1084 G1090.
23. Fahrmann M, Kaufhold M, Pfeiffer AF & Seidler U (2003). Protein kinase C-α attenuates cholinergically stimulated gastric acid secretion of rabbit parietal cells. Br J Pharmacol 139, 545 554.
24. Fahrmann M, Kaufhold M, Rieg T & Seidler U (2002). Different actions of protein kinase C isoforms α and ε on gastric acid secretion. Br J Pharmacol 136, 938 946.
25. Falk P, Roth KA & Gordon JI (1994). Lectins are sensitive tools for defining the differentiation programs of mouse gut epithelial cell lineages. Am J Physiol Gastrointest Liver Physiol 266, G987 1003.
26. Forte TM, Machen TE & Forte JG (1977). Ultrastructural changes in oxyntic cells associated with secretory function: a membrane-recycling hypothesis. Gastroenterology 73, 941 955.
27. Friis-Hansen L, Sundler F, Li Y, Gillespie PJ, Saunders TL, Greenson JK, Owyang C, Rehfeld JF & Samuelson LC (1998). Impaired gastric acid secretion in gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol 274, G561 G568.
28. Hanzel D, Reggio H, Bretscher A, Forte JG & Mangeat P (1991). The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli. EMBO J 10, 2363 2373.
29. Hegyi P, Gray MA & Argent BE (2003). Substance P inhibits bicarbonate secretion from guinea pig pancreatic ducts by modulating an anion exchanger. Am J Physiol Cell Physiol 285, C268 C276.
30. Hegyi P, Rakonczay Z Jr., Gray MA & Argent BE (2004). Measurement of intracellular pH in pancreatic duct cells: a new method for calibrating the fluorescence data. Pancreas 28, 427 434.
31. Herkenham M & Pert CB (1982). Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality. J Neurosci 2, 1129 1149.
32. Hersey SJ & Sachs G (1995). Gastric acid secretion. Physiol Rev 75, 155 189.
33. Hinkle KL, Bane GC, Jazayeri A & Samuelson LC (2003). Enhanced calcium signaling and acid secretion in parietal cells isolated from gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol 284, G145 G153.
34. Hussain I, Bate GW, Henry J, Djali P, Dimaline R, Dockray GJ & Varro A (1999). Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells. J Physiol 517, 495 505.
35. Jain RN, Brunkan CS, Chew CS & Samuelson LC (2006). Gene expression profiling of gastrin target genes in parietal cells. Physiol Genomics 24, 124 132.
36. Karam SM & Leblond CP (1992). Identifying and counting epithelial cell types in the "corpus" of the mouse stomach. Anat Rec 232, 231 246.
37. Khan ZE, Wang TC, Cui G, Chi AL & Dimaline R (2003). Transcriptional regulation of the human trefoil factor, TFF1, by gastrin1. Gastroenterology 125, 510 521.
38. Koh TJ, Goldenring JR, Ito S, Mashimo H, Kopin AS, Varro A, Dockray GJ & Wang TC (1997). Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. Gastroenterology 113, 1015 1025.
39. Kovacs TO, Walsh JH, Maxwell V, Wong HC, Azuma T & Katt E (1989). Gastrin is a major mediator of the gastric phase of acid secretion in dogs: proof by monoclonal antibody neutralization. Gastroenterology 97, 1406 1413.
40. Miyazaki Y, Shinomura Y, Tsutsui S, Zushi S, Higashimoto Y, Kanayama S, Higashiyama S, Taniguchi N & Matsuzawa Y (1999). Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor. Gastroenterology 116, 78 89.
41. +-ATPase recycling in the gastric parietal cell. J Physiol 532, 287 296.
42. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C & Ullrich A (1999). EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402, 884 888.
43. Sinclair NF, Ai W, Raychowdhury R, Bi M, Wang TC, Koh TJ & McLaughlin JT (2004). Gastrin regulates the heparin binding epidermal-like growth factor promoter via a PKC/EGFR dependent mechanism. Am J Physiol Gastrointest Liver Physiol 286, G992 G999.
44. Soll AH (1978). The interaction of histamine with gastrin and carbamylcholine on oxygen uptake by isolated mammalian parietal cells. J Clin Invest 61, 381 389.
45. Takeuchi Y, Yamada J, Yamada T & Todisco A (1997). Functional role of extracellular signal-regulated protein kinases in gastric acid secretion. Am J Physiol Gastrointest Liver Physiol 273, G1263 G1272.
46. Tamura A, Kikuchi S, Hata M, Katsuno T, Matsui T, Hayashi H, Suzuki Y, Noda T, Tsukita S & Tsukita S (2005). Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol 169, 21 28.
47. Thomas JA, Buchsbaum RN, Zimniak A & Racker E (1979). Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18, 2210 2218.
48. Todisco A, Takeuchi Y, Urumov A, Yamada J, Stepan VM & Yamada T (1997). Molecular mechanisms for the growth factor action of gastrin. Am J Physiol Gastrointest Liver Physiol 273, G891 G898.
49. Urushidani T, Hanzel DK & Forte JG (1987). Protein phosphorylation associated with stimulation of rabbit gastric glands. Biochim Biophys Acta 930, 209 219.
50. Varro A, Hemers E, Archer D, Pagliocca A, Haigh C, Ahmed S, Dimaline R & Dockray GJ (2002a). Identification of plasminogen activator inhibitor-2 as a gastrin-regulated gene: role of Rho GTPase and menin. Gastroenterology 123, 271 280.
51. B receptor expression in AGS cells is associated with direct inhibition and indirect stimulation of cell proliferation via paracrine activation of the epidermal growth factor receptor. Gut 50, 827 833.
52. Wang TC, Dangler CA, Chen D, Goldenring JR, Koh T, Raychowdhury R, Coffey RJ, Ito S, Varro A, Dockray GJ & Fox JG (2000). Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 118, 36 47.
53. Wroblewski LE, Noble PJ, Pagliocca A, Pritchard DM, Hart CA, Campbell F, Dodson AR, Dockray GJ & Varro A (2003). Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration. J Cell Sci 116, 3017 3026.
54. Yao X, Cheng L & Forte JG (1996). Biochemical characterization of ezrin-actin interaction. J Biol Chem 271, 7224 7229.
55. Yao X & Forte JG (2003). Cell biology of acid secretion by the parietal cell. Annu Rev Physiol 65, 103 131.
56. Zavros Y, Rieder G, Ferguson A, Samuelson LC & Merchant JL (2002). Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology 122, 119 133.
57. Zhou R, Cao X, Watson C, Miao Y, Guo Z, Forte JG & Yao X (2003). Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem 278, 35651 35659.
58. Zhou R, Zhu L, Kodani A, Hauser P, Yao X & Forte JG (2005). Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci 118, 4381 4391.
59. Zhu L, Liu Y & Forte JG (2005). Ezrin oligomers are the membrane-bound dormant form in gastric parietal cells. Am J Physiol Cell Physiol 288, C1242 C1254.