-
1
-
-
0025922923
-
2+ and other ions as extracellular (first) messengers
-
2+ and other ions as extracellular (first) messengers. Physiol. Rev. 71, 371-411.
-
(1991)
Physiol. Rev
, vol.71
, pp. 371-411
-
-
Brown, E.M.1
-
2
-
-
0019348378
-
Control, modulation, and regulation of cell calcium
-
Borle A. B. (1981) Control, modulation, and regulation of cell calcium. Rev. Physiol. Biochem. Pharmacol. 90, 13-153.
-
(1981)
Rev. Physiol. Biochem. Pharmacol
, vol.90
, pp. 13-153
-
-
Borle, A.B.1
-
3
-
-
0002471238
-
The divalent ion homeostatic system: Physiology and metabolism of calcium, phosphorus, magnesium, and bone
-
3rd edn, pp, Maxwell M. H. and Kleeman C. R, eds, McGraw-Hill, New York
-
Parfitt A. M. and Kleerekoper M. (1980) The divalent ion homeostatic system: Physiology and metabolism of calcium, phosphorus, magnesium, and bone. In: Clinical Disorders of Fluid and Electrolyte Metabolism, 3rd edn., pp. 269-398, Maxwell M. H. and Kleeman C. R. (eds.), McGraw-Hill, New York.
-
(1980)
Clinical Disorders of Fluid and Electrolyte Metabolism
, pp. 269-398
-
-
Parfitt, A.M.1
Kleerekoper, M.2
-
4
-
-
0027765508
-
2+ sensing receptor from bovine parathyroid
-
2+ sensing receptor from bovine parathyroid. Nature 366, 575-580.
-
(1993)
Nature
, vol.366
, pp. 575-580
-
-
Brown, E.M.1
Gamba, G.2
Riccardi, D.3
Lombardi, M.4
Butters, R.5
Kifor, O.6
Sun, A.7
Hediger, M.A.8
Lytton, J.9
Herbert, S.C.10
-
5
-
-
0001921697
-
Mineral metabolism
-
2nd edn, pp, Felig, P, Baxter, J. D, Broadus, A. F. and Frohman, L. A, eds, McGraw-Hill, New York
-
Stewart A. F. and Broadus A. E. (1987) Mineral metabolism. In: Endocrinology and Metabolism, 2nd edn., pp. 1317-1453, Felig, P., Baxter, J. D., Broadus, A. F. and Frohman, L. A. (eds.), McGraw-Hill, New York.
-
(1987)
Endocrinology and Metabolism
, pp. 1317-1453
-
-
Stewart, A.F.1
Broadus, A.E.2
-
6
-
-
0002972256
-
Parathyroid hormone, calcitonin, and the calciferols
-
7th edn, pp, Wilson J. D. and Foster D. W, eds, Saunders, Philadelphia
-
Aurbach G. D., Marx S. J. and Spiegel A. M. (1985) Parathyroid hormone, calcitonin, and the calciferols. In: Textbook of Endocrinology, 7th edn., pp. 1137-1217, Wilson J. D. and Foster D. W. (eds.), Saunders, Philadelphia.
-
(1985)
Textbook of Endocrinology
, pp. 1137-1217
-
-
Aurbach, G.D.1
Marx, S.J.2
Spiegel, A.M.3
-
7
-
-
53849137000
-
-
Brown E. M. (1983) Regulation of the synthesis, secretion and actions of parathyroid hormone. In: Contemporary Issues in Nephrology. Divalent Cation Homeostasis, 11, pp. 151-188, Brenner B. M. and Stein J. H. (eds.), Churchhill-Livingstone, New York.
-
Brown E. M. (1983) Regulation of the synthesis, secretion and actions of parathyroid hormone. In: Contemporary Issues in Nephrology. Divalent Cation Homeostasis, vol. 11, pp. 151-188, Brenner B. M. and Stein J. H. (eds.), Churchhill-Livingstone, New York.
-
-
-
-
8
-
-
3643138479
-
Mechanisms underlying the inverse control of parathyroid hormone secretion by calcium
-
Oxford G. and Armstrong C. M, eds, Rockfeller University Press, New York
-
Brown E. M., Chen C. J., Leboff M. S., Kifor O. and El-Hajj G. (1989) Mechanisms underlying the inverse control of parathyroid hormone secretion by calcium. In: Secretion and Its Control, pp. 252-268, Oxford G. and Armstrong C. M. (eds.), Rockfeller University Press, New York.
-
(1989)
Secretion and Its Control
, pp. 252-268
-
-
Brown, E.M.1
Chen, C.J.2
Leboff, M.S.3
Kifor, O.4
El-Hajj, G.5
-
9
-
-
0019799203
-
Calcitonin. Physiology and pathophysiology
-
Austin L. A. and Heath H. III (1981) Calcitonin. Physiology and pathophysiology. N. Engl. J. Med. 304, 269-278.
-
(1981)
N. Engl. J. Med
, vol.304
, pp. 269-278
-
-
Austin, L.A.1
Heath III, H.2
-
10
-
-
41849112423
-
Section II: Physiological aspects of the parathyroid
-
2nd edn, pp, Bilezikian J. P, Marcus R. and Levine M. A, eds, Academic Press, New York
-
Bilezikian JP, Marcus R and Levine MA (2003) Section II: Physiological aspects of the parathyroid. In: The Parathyroids: Basic and Clinical Concepts, 2nd edn., pp. 167-291, Bilezikian J. P., Marcus R. and Levine M. A. (eds.), Academic Press, New York.
-
(2003)
The Parathyroids: Basic and Clinical Concepts
, pp. 167-291
-
-
Bilezikian, J.P.1
Marcus, R.2
Levine, M.A.3
-
11
-
-
2442505055
-
Hormones and disorders of mineral metabolism
-
Bringhurst F. R, Demay M. B. and Kronenberg H. M, eds, Saunders, Philadelphia
-
Wilson J. D., Foster D. W., Kronenberg H. M. and Larsen P. R. (2003) Hormones and disorders of mineral metabolism. In: Williams Textbook of Endocrinology, pp. 1303-1371, Bringhurst F. R., Demay M. B. and Kronenberg H. M. (eds.), Saunders, Philadelphia.
-
(2003)
Williams Textbook of Endocrinology
, pp. 1303-1371
-
-
Wilson, J.D.1
Foster, D.W.2
Kronenberg, H.M.3
Larsen, P.R.4
-
12
-
-
0020508438
-
Rapidity of plasma 1,25-dihydroxyvitamin D responses to hypo- and hypercalcemia in steers
-
Blum J. W., Trescel U., Born W., Tobler P. H., Taylor C. M., Binswanger U. and Fischer J. A. (1983) Rapidity of plasma 1,25-dihydroxyvitamin D responses to hypo- and hypercalcemia in steers. Endocrinology 113, 523-526.
-
(1983)
Endocrinology
, vol.113
, pp. 523-526
-
-
Blum, J.W.1
Trescel, U.2
Born, W.3
Tobler, P.H.4
Taylor, C.M.5
Binswanger, U.6
Fischer, J.A.7
-
13
-
-
0021967676
-
The acute secretory response to alterations in the extracellular calcium concentration and dopamine in perifused bovine parathyroid cells
-
Brown E. M., Leombruno R., Thatcher J and Burrowes M. (1985) The acute secretory response to alterations in the extracellular calcium concentration and dopamine in perifused bovine parathyroid cells. Endocrinology 116, 1123-1132.
-
(1985)
Endocrinology
, vol.116
, pp. 1123-1132
-
-
Brown, E.M.1
Leombruno, R.2
Thatcher, J.3
Burrowes, M.4
-
14
-
-
0023950580
-
Kinetic evidence for cytoplasmic calcium as an inhibitory messenger in parathyroid hormone release
-
Wallfelt C., Lindh E., Larsson R., Johansson H., Rastad J., Akerstrom G. and Gylfe E. (1988) Kinetic evidence for cytoplasmic calcium as an inhibitory messenger in parathyroid hormone release. Biochim. Biophys. Acta 969, 257-262.
-
(1988)
Biochim. Biophys. Acta
, vol.969
, pp. 257-262
-
-
Wallfelt, C.1
Lindh, E.2
Larsson, R.3
Johansson, H.4
Rastad, J.5
Akerstrom, G.6
Gylfe, E.7
-
15
-
-
0000533560
-
Bone resorption in tissue culture: Factors influencing the response to parathyroid hormone
-
Raisz L. G. (1965) Bone resorption in tissue culture: Factors influencing the response to parathyroid hormone. J. Clin. Invest. 44, 103-110.
-
(1965)
J. Clin. Invest
, vol.44
, pp. 103-110
-
-
Raisz, L.G.1
-
16
-
-
0020623010
-
Regulation of bone formation
-
Raisz L. G. and Kream B. E. (1983) Regulation of bone formation. N. Engl. J. Med. 309, 35-39.
-
(1983)
N. Engl. J. Med
, vol.309
, pp. 35-39
-
-
Raisz, L.G.1
Kream, B.E.2
-
17
-
-
0346184677
-
Regulation of 25- hydroxycholecalciferol- hydroxylase activity in kidney by parathyroid hormone
-
Fraser D. R. and Kodicek E. (1973) Regulation of 25- hydroxycholecalciferol- hydroxylase activity in kidney by parathyroid hormone. Nat. New Biol. 241, 163-166.
-
(1973)
Nat. New Biol
, vol.241
, pp. 163-166
-
-
Fraser, D.R.1
Kodicek, E.2
-
20
-
-
0016622638
-
Cytoplasmic and nuclear binding components for 1,25-dihydroxyvitamin D3 in chick parathyroid glands
-
Brumbaugh P. F., Hughes M. R. and Haussler M. R. (1975) Cytoplasmic and nuclear binding components for 1,25-dihydroxyvitamin D3 in chick parathyroid glands. Proc. Natl. Acad. Sci. USA 72, 4871-4875.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 4871-4875
-
-
Brumbaugh, P.F.1
Hughes, M.R.2
Haussler, M.R.3
-
21
-
-
0020973759
-
Calciferols: Actions and deficiencies in actions
-
Marx S. J. Liberman U. A. and Eil C. A. (1983) Calciferols: Actions and deficiencies in actions. Vitam. Horm. 40, 235-308.
-
(1983)
Vitam. Horm
, vol.40
, pp. 235-308
-
-
Marx, S.J.1
Liberman, U.A.2
Eil, C.A.3
-
22
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsuki T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R and Nabeshima Y (1997) Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390, 45-51.
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-o, M.1
Matsumura, Y.2
Aizawa, H.3
Kawaguchi, H.4
Suga, T.5
Utsuki, T.6
Ohyama, Y.7
Kurabayashi, M.8
Kaname, T.9
Kume, E.10
Iwasaki, H.11
Iida, A.12
Shiraki-Iida, T.13
Nishikawa, S.14
Nagai, R.15
Nabeshima, Y.16
-
23
-
-
0030733350
-
Structural and sequence-based classification of glycoside hydrolases
-
Henrissat B and Davies G (1997) Structural and sequence-based classification of glycoside hydrolases. Curr. Opin. Struct. Biol. 7, 637-644.
-
(1997)
Curr. Opin. Struct. Biol
, vol.7
, pp. 637-644
-
-
Henrissat, B.1
Davies, G.2
-
24
-
-
2342610541
-
Secreted Klotho protein in sera and CSF: Implication for post-translational cleavage in release of Klotho protein from cell membrane
-
Imura A, Iwano A, Kita N, Thoyama O, Fujimori T and Nabeshima Y (2004) Secreted Klotho protein in sera and CSF: Implication for post-translational cleavage in release of Klotho protein from cell membrane. FEBS Lett. 565, 143-147.
-
(2004)
FEBS Lett
, vol.565
, pp. 143-147
-
-
Imura, A.1
Iwano, A.2
Kita, N.3
Thoyama, O.4
Fujimori, T.5
Nabeshima, Y.6
-
25
-
-
27144440831
-
The β-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
-
Chang Q., Hoefs S., van der Kemp A. W., Topala C. N., Bindels R. J. and Hoenderop J. G. (2005) The β-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 310, 490-493.
-
(2005)
Science
, vol.310
, pp. 490-493
-
-
Chang, Q.1
Hoefs, S.2
van der Kemp, A.W.3
Topala, C.N.4
Bindels, R.J.5
Hoenderop, J.G.6
-
26
-
-
2342599742
-
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression
-
Takeshita K., Fujimori T., Kurotaki Y., Honjo H., Tsujikawa H., Yasui K., Lee J. K., Kamiya K., Kitaichi K., Yamamoto K., Ito M., Kondo T., Iino S., Inden Y., Hirai M., Murohara T., Kodama I. and Nabeshima Y. (2004) Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation 109, 1776-1782.
-
(2004)
Circulation
, vol.109
, pp. 1776-1782
-
-
Takeshita, K.1
Fujimori, T.2
Kurotaki, Y.3
Honjo, H.4
Tsujikawa, H.5
Yasui, K.6
Lee, J.K.7
Kamiya, K.8
Kitaichi, K.9
Yamamoto, K.10
Ito, M.11
Kondo, T.12
Iino, S.13
Inden, Y.14
Hirai, M.15
Murohara, T.16
Kodama, I.17
Nabeshima, Y.18
-
27
-
-
0035138842
-
Extracellular calcium sensing and extra cellular calcium signaling
-
Brown E. M. and MacLead R. J. (2001) Extracellular calcium sensing and extra cellular calcium signaling. Physiol. Rev. 81. 239-297.
-
(2001)
Physiol. Rev
, vol.81
, pp. 239-297
-
-
Brown, E.M.1
MacLead, R.J.2
-
28
-
-
0347320924
-
2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
-
2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5. J. Clin. Invest. 112, 1906-1914.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1906-1914
-
-
Hoenderop, J.G.1
Leeuwen, J.P.2
Eerden, B.C.3
Kersten, F.F.4
Emp, A.W.5
Merillat, A.M.6
Waarsing, J.H.7
Rossier, B.C.8
Vallon, V.9
Hummler, E.10
Bindels, R.J.11
-
29
-
-
0026888226
-
Regulation of solute and water balance and cell volume in the central nervous system
-
Strange K. (1992) Regulation of solute and water balance and cell volume in the central nervous system. J. Am. Soc. Nephrol. 3, 12-27.
-
(1992)
J. Am. Soc. Nephrol
, vol.3
, pp. 12-27
-
-
Strange, K.1
-
30
-
-
0036107388
-
Ion regulation in the brain: Implications for pathophysiology
-
Somjen G. G. (2002) Ion regulation in the brain: Implications for pathophysiology. Neuroscientist 8, 254-267.
-
(2002)
Neuroscientist
, vol.8
, pp. 254-267
-
-
Somjen, G.G.1
-
31
-
-
34250803923
-
α-Klotho as a regulator of calcium homeostasis
-
Imura A., Tsuji Y., Murata M., Maeda R., Kubota K., Iwano A., Obuse C., Togashi K., Tominaga M., Kita N., Tomiyama K., Iijima J., Nabeshima Y., Fujioka M., Asato R., Tanaka S., Kojima K., Ito J., Nozaki K., Hashimoto N., Ito T., Nishio T., Uchiyama T., Fujimori T. and Nabeshima Y. (2007) α-Klotho as a regulator of calcium homeostasis. Science 316, 1615-1618.
-
(2007)
Science
, vol.316
, pp. 1615-1618
-
-
Imura, A.1
Tsuji, Y.2
Murata, M.3
Maeda, R.4
Kubota, K.5
Iwano, A.6
Obuse, C.7
Togashi, K.8
Tominaga, M.9
Kita, N.10
Tomiyama, K.11
Iijima, J.12
Nabeshima, Y.13
Fujioka, M.14
Asato, R.15
Tanaka, S.16
Kojima, K.17
Ito, J.18
Nozaki, K.19
Hashimoto, N.20
Ito, T.21
Nishio, T.22
Uchiyama, T.23
Fujimori, T.24
Nabeshima, Y.25
more..
-
32
-
-
0033763097
-
Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
-
The ADHR Consortium
-
The ADHR Consortium (2000) Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. Nat. Genet. 26, 345-348.
-
(2000)
Nat. Genet
, vol.26
, pp. 345-348
-
-
-
33
-
-
0034703619
-
Identification of a novel fibroblast growth factor, FGF23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
-
Yamashita T., Yoshioka M. and Itoh N. (2000) Identification of a novel fibroblast growth factor, FGF23, preferentially expressed in the ventrolateral thalamic nucleus of the brain. Biochem. Biophys. Res. Commun. 277, 494-498.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.277
, pp. 494-498
-
-
Yamashita, T.1
Yoshioka, M.2
Itoh, N.3
-
34
-
-
4744372082
-
Evolution of the Fgf and Fgfr gene families
-
Itoh N. and Ornitz D. M. (2004) Evolution of the Fgf and Fgfr gene families. Trends Genet. 20, 563-569.
-
(2004)
Trends Genet
, vol.20
, pp. 563-569
-
-
Itoh, N.1
Ornitz, D.M.2
-
35
-
-
0035186837
-
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF23
-
White K. E., Carn G., Lorenz-Depiereux B., Benet-Pages A., Strom T. M. and Econs M. G. (2001) Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF23. Kidney Int. 60, 2079-2086.
-
(2001)
Kidney Int
, vol.60
, pp. 2079-2086
-
-
White, K.E.1
Carn, G.2
Lorenz-Depiereux, B.3
Benet-Pages, A.4
Strom, T.M.5
Econs, M.G.6
-
36
-
-
18444375871
-
Mutant FGF23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo
-
Shimada T., Muto T., Urakawa I., Yoneya T., Yamazaki Y., Okawa K., Takeuchi Y., Fujita T., Fukumoto S. and Yamashita T. (2002) Mutant FGF23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo. Endocrinology 143, 3179-3182.
-
(2002)
Endocrinology
, vol.143
, pp. 3179-3182
-
-
Shimada, T.1
Muto, T.2
Urakawa, I.3
Yoneya, T.4
Yamazaki, Y.5
Okawa, K.6
Takeuchi, Y.7
Fujita, T.8
Fukumoto, S.9
Yamashita, T.10
-
37
-
-
14344279878
-
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
-
Shimada T., Mizutani S., Muto T., Yoneda T., Hino R., Takeda S., Takeuchi Y., Fujita T., Fukumoto S. and Yamashita T. (2001) Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc. Natl. Acad. Sci. USA 98, 6500-6505.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6500-6505
-
-
Shimada, T.1
Mizutani, S.2
Muto, T.3
Yoneda, T.4
Hino, R.5
Takeda, S.6
Takeuchi, Y.7
Fujita, T.8
Fukumoto, S.9
Yamashita, T.10
-
38
-
-
0013118819
-
The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
-
Bai XY, Miao D, Goltzman D. and Karaplis A, C. (2003) The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. J. Biol. Chem. 278, 9843-9849.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 9843-9849
-
-
Bai, X.Y.1
Miao, D.2
Goltzman, D.3
Karaplis, A.C.4
-
39
-
-
9144248333
-
FGF23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa
-
Shimada T., Urakawa I., Yamazaki Y., Hasegawa H., Hino R., Yoneya T., Takeuchi Y., Fujita T., Fukumoto S. and Yamashita T. (2004) FGF23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa. Biochem. Biophys. Res. Commun. 314, 409-414.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.314
, pp. 409-414
-
-
Shimada, T.1
Urakawa, I.2
Yamazaki, Y.3
Hasegawa, H.4
Hino, R.5
Yoneya, T.6
Takeuchi, Y.7
Fujita, T.8
Fukumoto, S.9
Yamashita, T.10
-
40
-
-
3042634460
-
Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis
-
Larsson T., Marsell R., Schipani E., Ohlsson C., Ljunggren O., Tenenhouse H. S., Jüppner H. and Jonsson K. B. (2004) Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. Endocrinology 145, 87-94.
-
(2004)
Endocrinology
, vol.145
, pp. 87-94
-
-
Larsson, T.1
Marsell, R.2
Schipani, E.3
Ohlsson, C.4
Ljunggren, O.5
Tenenhouse, H.S.6
Jüppner, H.7
Jonsson, K.B.8
-
41
-
-
9244240970
-
Transgenic mice overexpressing human fibroblast growth factor 23(R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
-
Bai X., Miao D., Li J., Goltzman D. and Karaplis A. C. (2004) Transgenic mice overexpressing human fibroblast growth factor 23(R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. Endocrinology 145, 5269-5279.
-
(2004)
Endocrinology
, vol.145
, pp. 5269-5279
-
-
Bai, X.1
Miao, D.2
Li, J.3
Goltzman, D.4
Karaplis, A.C.5
-
42
-
-
1642416884
-
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
-
Shimada T., Kakitani M., Yamazaki Y., Hasegawa H., Takeuchi Y., Fujita T., Fukumoto S., Tomizuka K. and Yamashita T. (2004) Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J. Clin. Invest. 113, 561-568.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 561-568
-
-
Shimada, T.1
Kakitani, M.2
Yamazaki, Y.3
Hasegawa, H.4
Takeuchi, Y.5
Fujita, T.6
Fukumoto, S.7
Tomizuka, K.8
Yamashita, T.9
-
43
-
-
9644303231
-
Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice
-
Sitara D., Razzaque M. S., Hesse M., Yoganathan S., Taguchi T., Erben R. G., Jüppner H. and Lanske B. (2004) Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol. 23, 421-432.
-
(2004)
Matrix Biol
, vol.23
, pp. 421-432
-
-
Sitara, D.1
Razzaque, M.S.2
Hesse, M.3
Yoganathan, S.4
Taguchi, T.5
Erben, R.G.6
Jüppner, H.7
Lanske, B.8
-
44
-
-
2142746439
-
FGF23 is a potent regulator of the vitamin D metabolism and phosphate homeostasis
-
Shimada T., Hasegawa H., Yamazaki Y., Muto T., Hino R., Takeuchi Y., Fujita T., Nakahara K., Fukumoto S. and Yamashita T. (2004) FGF23 is a potent regulator of the vitamin D metabolism and phosphate homeostasis. J. Bone Miner. Res. 19, 429-435.
-
(2004)
J. Bone Miner. Res
, vol.19
, pp. 429-435
-
-
Shimada, T.1
Hasegawa, H.2
Yamazaki, Y.3
Muto, T.4
Hino, R.5
Takeuchi, Y.6
Fujita, T.7
Nakahara, K.8
Fukumoto, S.9
Yamashita, T.10
-
45
-
-
0042830485
-
Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter
-
Segawa H., Kawakami E., Kaneko I., Kuwahata M., Ito M., Kusano K., Saito H., Fukushima N. and Miyamoto K. (2003) Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter. Pflugers Arch. 446, 585-592.
-
(2003)
Pflugers Arch
, vol.446
, pp. 585-592
-
-
Segawa, H.1
Kawakami, E.2
Kaneko, I.3
Kuwahata, M.4
Ito, M.5
Kusano, K.6
Saito, H.7
Fukushima, N.8
Miyamoto, K.9
-
46
-
-
0346849707
-
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
-
Tsujikawa H., Kurotaki Y., Fujimori T., Fukuda K. and Nabeshima Y. (2003) Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol. Endocrinol. 17, 2393-2403.
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 2393-2403
-
-
Tsujikawa, H.1
Kurotaki, Y.2
Fujimori, T.3
Fukuda, K.4
Nabeshima, Y.5
-
47
-
-
33746341155
-
Hypervitaminosis D and premature aging: Lessons learned from Fgf23 and Klotho mutant mice
-
Razzaque M. S. and Lanske B. (2006) Hypervitaminosis D and premature aging: Lessons learned from Fgf23 and Klotho mutant mice. Trends Mol. Med. 12, 298-305.
-
(2006)
Trends Mol. Med
, vol.12
, pp. 298-305
-
-
Razzaque, M.S.1
Lanske, B.2
-
48
-
-
33646238028
-
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
-
Razzaque M. S., Sutara D., Taguchi T., St-Arnaud R. and Lanske B. (2006) Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J. 20, 720-722.
-
(2006)
FASEB J
, vol.20
, pp. 720-722
-
-
Razzaque, M.S.1
Sutara, D.2
Taguchi, T.3
St-Arnaud, R.4
Lanske, B.5
-
49
-
-
33744550350
-
-
Nabeshima Y. (2006) Toward a better understanding of Klotho. Sci. Aging Knowledge Environ 8, pe11.
-
Nabeshima Y. (2006) Toward a better understanding of Klotho. Sci. Aging Knowledge Environ 8, pe11.
-
-
-
-
50
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for FGF23
-
Urakawa I., Yamazaki Y., Shimada T., Iijima K., Hasegawa H., Okawa K., Fujita T., Fukumoto S. and Yamashita T. (2006) Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 444, 770-774.
-
(2006)
Nature
, vol.444
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
Iijima, K.4
Hasegawa, H.5
Okawa, K.6
Fujita, T.7
Fukumoto, S.8
Yamashita, T.9
-
51
-
-
34250664015
-
Mineral metabolism and aging: The fibroblast growth factor 23 enigma
-
Lanske B. and Razzaque M. S. (2007) Mineral metabolism and aging: The fibroblast growth factor 23 enigma. Curr. Opin. Nephrol. Hypertens. 16, 311-318.
-
(2007)
Curr. Opin. Nephrol. Hypertens
, vol.16
, pp. 311-318
-
-
Lanske, B.1
Razzaque, M.S.2
-
52
-
-
34247490227
-
Premature aging in klotho mutant mice: Cause or consequence?
-
Lanske B. and Razzaque M. S. (2007) Premature aging in klotho mutant mice: Cause or consequence? Ageing Res. Rev. 6, 73-79.
-
(2007)
Ageing Res. Rev
, vol.6
, pp. 73-79
-
-
Lanske, B.1
Razzaque, M.S.2
-
53
-
-
33745828096
-
Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation
-
Kato K, Jeanneau C, Tarp MA, Benet-Pagès A, Lorenz-Depiereux B, Bennett EP, Mandel U, Strom TM and Clausen H. (2006) Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation. J. Biol. Chem. 281, 18370-18377.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18370-18377
-
-
Kato, K.1
Jeanneau, C.2
Tarp, M.A.3
Benet-Pagès, A.4
Lorenz-Depiereux, B.5
Bennett, E.P.6
Mandel, U.7
Strom, T.M.8
Clausen, H.9
-
54
-
-
34848871595
-
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis
-
Ichikawa S., Imel E. A., Kreiter M. L., Xijie Yu, Donald S., Mackenzie B. S., Sorenson A. H., Goetz R., Mohammadi M., White K. E. and Econs M. J. (2007) A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. J. Clin. Invest. 117, 2684-269.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2684-3269
-
-
Ichikawa, S.1
Imel, E.A.2
Kreiter, M.L.3
Yu, X.4
Donald, S.5
Mackenzie, B.S.6
Sorenson, A.H.7
Goetz, R.8
Mohammadi, M.9
White, K.E.10
Econs, M.J.11
-
55
-
-
42149130855
-
A translocation causing increased α-Klotho level results in hypophosphatemic rickets and hyperparathyroidism
-
Brownstein C. A., Adler F. , Nelson-Williams C., Iijima J. , Li P. , Imura A., Nabeshima Y., Reyes-Mugica M. , Carpenter T. O. and Lifton R. P. (2008) A translocation causing increased α-Klotho level results in hypophosphatemic rickets and hyperparathyroidism. Proc. Natl. Acad. Sci. USA 105, 3455-3460.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3455-3460
-
-
Brownstein, C.A.1
Adler, F.2
Nelson-Williams, C.3
Iijima, J.4
Li, P.5
Imura, A.6
Nabeshima, Y.7
Reyes-Mugica, M.8
Carpenter, T.O.9
Lifton, R.P.10
-
57
-
-
41849101973
-
α-Klotho: A regulator that integrates calcium homeostasis
-
Nabeshima Y. and Imura H. (2007) α-Klotho: A regulator that integrates calcium homeostasis. Am. J. Nephrol. 28, 455-464.
-
(2007)
Am. J. Nephrol
, vol.28
, pp. 455-464
-
-
Nabeshima, Y.1
Imura, H.2
-
60
-
-
34548714102
-
2+ transport
-
2+ transport. Biochem. J. 406, 365-382.
-
(2007)
Biochem. J
, vol.406
, pp. 365-382
-
-
Lytton, J.1
-
61
-
-
0032801648
-
Sodium/calcium exchange: Its physiological implications
-
Blaustein M. P. and Lederer W. J. (1999) Sodium/calcium exchange: Its physiological implications. Physiol. Rev. 79, 763-854.
-
(1999)
Physiol. Rev
, vol.79
, pp. 763-854
-
-
Blaustein, M.P.1
Lederer, W.J.2
-
62
-
-
0343383379
-
Micropuncture study of renal tubular reabsorption of calcium in normal rodents
-
Lassiter W. C., Gottschalk C. W. and Mylle M. (1963) Micropuncture study of renal tubular reabsorption of calcium in normal rodents. Am. J. Physiol. 204, 771-775.
-
(1963)
Am. J. Physiol
, vol.204
, pp. 771-775
-
-
Lassiter, W.C.1
Gottschalk, C.W.2
Mylle, M.3
-
63
-
-
0017397322
-
Calcium and phosphate transport in isolated segments of rabbit Henle's loop
-
Rocha A. S., Magaldi J. B. and Kokko J. P. (1977) Calcium and phosphate transport in isolated segments of rabbit Henle's loop. J. Clin. Invest. 59, 975-983.
-
(1977)
J. Clin. Invest
, vol.59
, pp. 975-983
-
-
Rocha, A.S.1
Magaldi, J.B.2
Kokko, J.P.3
-
64
-
-
0018499901
-
Calcium transport in the nephron
-
Suki W. N. (1979) Calcium transport in the nephron. Am. J. Physiol. 237, F1-F6.
-
(1979)
Am. J. Physiol
, vol.237
-
-
Suki, W.N.1
-
65
-
-
0016228201
-
Localization of a calcium stimulated ATPase in the basal-lateral plasma membranes of the proximal tubule of rat kidney cortex
-
Kinne-Saffran E. and Kinne R. (1974) Localization of a calcium stimulated ATPase in the basal-lateral plasma membranes of the proximal tubule of rat kidney cortex. J. Membr. Biol. 17, 263-274.
-
(1974)
J. Membr. Biol
, vol.17
, pp. 263-274
-
-
Kinne-Saffran, E.1
Kinne, R.2
-
67
-
-
0018027842
-
Calcium transport across segments of the rabbit distal nephron in vitro
-
Shareghi G. R. and Stoner L. C. (1978) Calcium transport across segments of the rabbit distal nephron in vitro. Am. J. Physiol. 235, F367-F375.
-
(1978)
Am. J. Physiol
, vol.235
-
-
Shareghi, G.R.1
Stoner, L.C.2
-
68
-
-
0019025880
-
Effect of calcitonin on calcium and magnesium transport in rat nephron
-
Quamme G. A. (1980) Effect of calcitonin on calcium and magnesium transport in rat nephron. Am. J. Physiol. 238, E573-E578.
-
(1980)
Am. J. Physiol
, vol.238
-
-
Quamme, G.A.1
-
69
-
-
0020371028
-
Effect of hypercalcemia on renal tubular handling of calcium and magnesium
-
Quamme G. A. (1982) Effect of hypercalcemia on renal tubular handling of calcium and magnesium. Can. J. Physiol. Pharmacol. 60, 1275-1280.
-
(1982)
Can. J. Physiol. Pharmacol
, vol.60
, pp. 1275-1280
-
-
Quamme, G.A.1
-
70
-
-
17644447893
-
Renal tubular calcium transport: Effects of changes in filtered calcium load
-
Sutton R. A., Wong N. L., Quamme G. A. and Dirks J. H. (1983) Renal tubular calcium transport: Effects of changes in filtered calcium load. Am. J. Physiol. 245, F515-F520.
-
(1983)
Am. J. Physiol
, vol.245
-
-
Sutton, R.A.1
Wong, N.L.2
Quamme, G.A.3
Dirks, J.H.4
-
71
-
-
0028845670
-
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
-
Ho C., Conner D. A., Pollack M. R., Ladd D. J., Kifor O., Warren H. B., Brown E. M., Seidman J. G. and Seidman C. E. (1995) A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat. Genet. 11, 389-394.
-
(1995)
Nat. Genet
, vol.11
, pp. 389-394
-
-
Ho, C.1
Conner, D.A.2
Pollack, M.R.3
Ladd, D.J.4
Kifor, O.5
Warren, H.B.6
Brown, E.M.7
Seidman, J.G.8
Seidman, C.E.9
-
72
-
-
33749647718
-
Defect in parathyroid-hormone-induced luminal calcium absorption in connecting tubules of Klotho mice
-
Tsuruoka S., Nishiki K., Ioka T., Ando H., Saito Y., Kurabayashi M., Nagai R. and Fujimura A. (2006) Defect in parathyroid-hormone-induced luminal calcium absorption in connecting tubules of Klotho mice. Nephrol. Dial. Transplant. 21, 2762-2767.
-
(2006)
Nephrol. Dial. Transplant
, vol.21
, pp. 2762-2767
-
-
Tsuruoka, S.1
Nishiki, K.2
Ioka, T.3
Ando, H.4
Saito, Y.5
Kurabayashi, M.6
Nagai, R.7
Fujimura, A.8
-
73
-
-
0023158585
-
Ouabain and low extracellular potassium inhibit PTH secretion from bovine parathyroid cells by a mechanism that does not involve increases in the cytosolic calcium concentration
-
Brown E. M., Watson E. J., Thatcher J. G., Koletsky R., Dawson-Hughes B. F., Posillico J. T. and Shoback D. M. (1987) Ouabain and low extracellular potassium inhibit PTH secretion from bovine parathyroid cells by a mechanism that does not involve increases in the cytosolic calcium concentration. Metabolism 36, 36-42.
-
(1987)
Metabolism
, vol.36
, pp. 36-42
-
-
Brown, E.M.1
Watson, E.J.2
Thatcher, J.G.3
Koletsky, R.4
Dawson-Hughes, B.F.5
Posillico, J.T.6
Shoback, D.M.7
-
74
-
-
1642352496
-
Klotho is a novel β-glucuronidase capable of hydrolyzing steroid β-glucuronides
-
Tohyama O., Imura A., Iwano A., Freund J. N., Henrissat B., Fujimori T. and Nabeshima Y. (2004) Klotho is a novel β-glucuronidase capable of hydrolyzing steroid β-glucuronides. J Biol. Chem. 273, 9777-9784.
-
(2004)
J Biol. Chem
, vol.273
, pp. 9777-9784
-
-
Tohyama, O.1
Imura, A.2
Iwano, A.3
Freund, J.N.4
Henrissat, B.5
Fujimori, T.6
Nabeshima, Y.7
-
75
-
-
0032574725
-
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities
-
Beck L., Karaplis A. C., Amizuka N., Hewson A. S., Ozawa H. and Tenenhouse H. S. (1998) Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc. Natl. Acad. Sci. USA 95, 5372-5377.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5372-5377
-
-
Beck, L.1
Karaplis, A.C.2
Amizuka, N.3
Hewson, A.S.4
Ozawa, H.5
Tenenhouse, H.S.6
-
76
-
-
23944521772
-
Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter
-
Tenenhouse H. (2005) Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter. Annu. Rev. Nutr. 25:197-214.
-
(2005)
Annu. Rev. Nutr
, vol.25
, pp. 197-214
-
-
Tenenhouse, H.1
-
77
-
-
33750203846
-
Proximal tubular handling of phosphate: A molecular perspective
-
Forster I. C., Hernando N., Biber J. and Murer H. (2006) Proximal tubular handling of phosphate: A molecular perspective. Kidney Int. 70, 1548-1559.
-
(2006)
Kidney Int
, vol.70
, pp. 1548-1559
-
-
Forster, I.C.1
Hernando, N.2
Biber, J.3
Murer, H.4
-
78
-
-
0032539622
-
Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter
-
Pfister M. F., Ruf I., Stange G., Ziegler U., Lederer E., Biber J. and Murer H. (1998) Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter. Proc. Natl. Acad. Sci. USA. 95, 1909-1914.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1909-1914
-
-
Pfister, M.F.1
Ruf, I.2
Stange, G.3
Ziegler, U.4
Lederer, E.5
Biber, J.6
Murer, H.7
-
79
-
-
0035937757
-
A conserved cis-acting element in the parathyroid hormone 3′-untranslated region is sufficient for regulation of RNA stability by calcium and phosphate
-
Kilav R., Silver J. and Naveh-Many T. (2001) A conserved cis-acting element in the parathyroid hormone 3′-untranslated region is sufficient for regulation of RNA stability by calcium and phosphate. J. Biol. Chem. 276, 8727-8733.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 8727-8733
-
-
Kilav, R.1
Silver, J.2
Naveh-Many, T.3
-
80
-
-
0032570574
-
RNA-protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate
-
Moallem E., Kilav R., Silver J. and Naveh-Many T. (1998) RNA-protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate. J. Biol. Chem. 273, 5253-5259.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 5253-5259
-
-
Moallem, E.1
Kilav, R.2
Silver, J.3
Naveh-Many, T.4
-
81
-
-
17644394206
-
Identification and characterization of cis-acting elements in the human and bovine PTH mRNA 3′-untranslated region
-
Bell O., Silver J. and Naveh-Many T. (2005) Identification and characterization of cis-acting elements in the human and bovine PTH mRNA 3′-untranslated region. J. Bone Miner. Res. 20, 858-866.
-
(2005)
J. Bone Miner. Res
, vol.20
, pp. 858-866
-
-
Bell, O.1
Silver, J.2
Naveh-Many, T.3
-
83
-
-
33847076432
-
Concerted action of associated proteins in the regulation of TRPV5 and TRPV6
-
Schoeber J. P. H., Hoenderop J. G. J. and Bindels R. J. M. (2007) Concerted action of associated proteins in the regulation of TRPV5 and TRPV6. Biochem. Soc. Trans. 35, 115-119.
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 115-119
-
-
Schoeber, J.P.H.1
Hoenderop, J.G.J.2
Bindels, R.J.M.3
|