Microsome biocolloids for rapid drug metabolism and inhibition assessment by LC-MS

Drug Metabolism Letters

Volumn 2, Issue 3, 2008, Pages 158-162

  Bajrami, Besnik ^a   Krishnan, Sadagopan ^a   Rusling, James F ^a,b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Cap LC MS; CYP; Inhibition; Ketoconazole; Microsome biocolloids; N nitrosamines

Indexed keywords

4 METHYLPYRAZOLE; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; KETOCONAZOLE; NANOPARTICLE;

ANIMAL CELL; ARTICLE; COLLOID; CONTROLLED STUDY; DRUG METABOLISM; ENZYME INHIBITION; ENZYME METABOLISM; IC 50; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; TURNOVER TIME;

ANIMALS; CHROMATOGRAPHY, LIQUID; COLLOIDS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; KETOCONAZOLE; MICROSOMES, LIVER; NANOPARTICLES; NITROSO COMPOUNDS; PYRAZOLES; RATS; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 53749107273     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231208785425854     Document Type: Article

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