Dose-dependent lymphocyte apoptosis following respiratory infection with Vaccinia virus

Virus Research

Volumn 137, Issue 2, 2008, Pages 198-205

  Yates, Nicole L ^a   Yammani, Rama D ^a   Alexander Miller, Martha A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Immunosuppression; Respiratory infection; Vaccinia virus

Indexed keywords

CORTICOSTERONE; CYTOKINE; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 12P70; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL LOSS; CELL POPULATION; CORTICOSTERONE BLOOD LEVEL; DOSE RESPONSE; FEMALE; FLOW CYTOMETRY; IMMUNE RESPONSE; LYMPHOCYTE; MEMORY T LYMPHOCYTE; MOUSE; NEWBORN; NONHUMAN; POXVIRUS INFECTION; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; VACCINIA VIRUS; VIRUS PATHOGENESIS; WEIGHT REDUCTION;

ANIMALS; APOPTOSIS; CYTOKINES; FEMALE; HUMANS; LYMPHOCYTES; MICE; MICE, INBRED C57BL; RESPIRATORY TRACT INFECTIONS; SPLEEN; VACCINIA; VACCINIA VIRUS; WEIGHT LOSS;

MUS; POXVIRIDAE; VACCINIA VIRUS;

EID: 53749104343     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2008.07.010     Document Type: Article

References (47)

1. Adair B.M. Immunopathogenesis of chicken anemia virus infection. Dev. Comp. Immunol. 24 (2000) 247-255
2. Alam A., Cohen L.Y., Aouad S., and Sekaly R.P. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J. Exp. Med. 190 (1999) 1879-1890
3. Alexander-Miller M.A., Derby M.A., Sarin A., Henkart P.A., and Berzofsky J.A. Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes. J. Exp. Med. 188 (1998) 1391-1399
4. + T cell homeostasis by perforin and interferon-gamma. Science 290 (2000) 1354-1358
5. Bahl K., Kim S.K., Calcagno C., Ghersi D., Puzone R., Celada F., Selin L.K., and Welsh R.M. IFN-induced attrition of CD8 T cells in the presence or absence of cognate antigen during the early stages of viral infections. J. Immunol. 176 (2006) 4284-4295
6. Baize S., Leroy E.M., Georges-Courbot M.C., Capron M., Lansoud-Soukate J., Debre P., Fisher-Hoch S.P., McCormick J.B., and Georges A.J. Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients. Nat. Med. 5 (1999) 423-426
7. Baron S. Smallpox: the main site of transmission is the oropharynx. J. Dent. Res. 82 (2003) 252
8. Belyakov I.M., Earl P., Dzutsev A., Kuznetsov V.A., Lemon M., Wyatt L.S., Snyder J.T., Ahlers J.D., Franchini G., Moss B., and Berzofsky J.A. Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 9458-9463
9. + lymphocytes. J. Immunol. 158 (1997) 5589-5595
10. Buller R.M.L., Smith G.L., Cremer K., Notkins A.L., and Moss B. Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype. Nature 317 (1985) 813-815
11. Carrero J.A., Calderon B., and Unanue E.R. Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. J. Exp. Med. 200 (2004) 535-540
12. Chakrabarti S., Brechling K., and Moss B. Vaccinia virus expression vector-coexpression of beta-galactosidase provides visual screening of recombinant virus plaques. Mol. Cell. Biol. 5 (1985) 3403-3409
13. Chan F.K., Shisler J., Bixby J.G., Felices M., Zheng L., Appel M., Orenstein J., Moss B., and Lenardo M.J. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J. Biol. Chem. 278 (2003) 51613-51621
14. Dalton D.K., Haynes L., Chu C.Q., Swain S.L., and Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J. Exp. Med. 192 (2000) 117-122
15. Dunlop L.R., Oehlberg K.A., Reid J.J., Avci D., and Rosengard A.M. Variola virus immune evasion proteins. Microbes Infect. 5 (2003) 1049-1056
16. Florido M., Pearl J.E., Solache A., Borges M., Haynes L., Cooper A.M., and Appelberg R. Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection. Infect. Immun. 73 (2005) 3577-3586
17. Haga I.R., and Bowie A.G. Evasion of innate immunity by vaccinia virus. Parasitology 130 Suppl. (2005) S11-S25
18. Harper G.J. Airborne micro-organisms: survival tests with four viruses. J. Hyg. (Lond.) 59 (1961) 479-486
19. Harrington L.E., Most R.R., Whitton J.L., and Ahmed R. Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J. Virol. 76 (2002) 3329-3337
20. Hassan J.O., and Curtiss III R. Virulent Salmonella typhimurium-induced lymphocyte depletion and immunosuppression in chickens. Infect. Immun. 62 (1994) 2027-2036
21. He Z., Zhao C., Dong Q., Zhuang H., Song S., Peng G., and Dwyer D.E. Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets. Int. J. Infect. Dis. 9 (2005) 323-330
22. Kim K.D., Choe Y.K., Choe I.S., and Lim J.S. Inhibition of glucocorticoid-mediated, caspase-independent dendritic cell death by CD40 activation. J. Leukoc. Biol. 69 (2001) 426-434
23. Martins G.A., Vieira L.Q., Cunha F.Q., and Silva J.S. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infect. Immun. 67 (1999) 3864-3871
24. McNally J.M., Zarozinski C.C., Lin M.Y., Brehm M.A., Chen H.D., and Welsh R.M. Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J. Virol. 75 (2001) 5965-5976
25. Miossec C., Dutilleul V., Fassy F., and Diu-Hercend A. Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation. J. Biol. Chem. 272 (1997) 13459-13462
26. Moore J.B., and Smith G.L. Steroid hormone synthesis by a Vaccinia enzyme: a new type of virus virulence factor. EMBO J. 11 (1992) 1973-1980
27. Okada H., Kobune F., Sato T.A., Kohama T., Takeuchi Y., Abe T., Takayama N., Tsuchiya T., and Tashiro M. Extensive lymphopenia due to apoptosis of uninfected lymphocytes in acute measles patients. Arch. Virol. 145 (2000) 905-920
28. Orange J.S., Salazarmather T.P., Opal S.M., Spencer R.L., Miller A.H., Mcewen B.S., and Biron C.A. Mechanism of interleukin 12-mediated toxicities during experimental viral-infections - role of tumor-necrosis-factor and glucocorticoids. J. Exp. Med. 181 (1995) 901-914
29. Parks G.D., and Alexander-Miller M.A. High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5. J. Gen. Virol. 83 (2002) 1167-1172
30. Piemonti L., Monti P., Allavena P., Sironi M., Soldini L., Leone B.E., Socci C., and Di C.V. Glucocorticoids affect human dendritic cell differentiation and maturation. J. Immunol. 162 (1999) 6473-6481
31. Ramirez J.C., Gherardi M.M., and Esteban M. Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine. J. Virol. 74 (2000) 923-933
32. Reading P.C., and Smith G.L. A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J. Gen. Virol. 84 (2003) 1973-1983
33. Reading P.C., Moore J.B., and Smith G.L. Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection. J. Exp. Med. 197 (2003) 1269-1278
34. Restifo N.P., Bacik I., Irvine K.R., Yewdell J.W., McCabe B.J., Anderson R.W., Eisenlohr L.C., Rosenberg S.A., and Bennink J.R. Antigen processing in vivo and the elicitation of primary CTL responses. J. Immunol. 154 (1995) 4414-4422
35. Roe M.F., Bloxham D.M., White D.K., Ross-Russell R.I., Tasker R.T., and O'Donnell D.R. Lymphocyte apoptosis in acute respiratory syncytial virus bronchiolitis. Clin. Exp. Immunol. 137 (2004) 139-145
36. Rojko J.L., Hartke J.R., Cheney C.M., Phipps A.J., and Neil J.C. Cytopathic feline leukemia viruses cause apoptosis in hemolymphatic cells. Prog. Mol. Subcell. Biol. 16 (1996) 13-43
37. Sabbagh L., Kaech S.M., Bourbonniere M., Woo M., Cohen L.Y., Haddad E.K., Labrecque N., Ahmed R., and Sekaly R.P. The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. J. Immunol. 173 (2004) 5425-5433
38. Sanchez-Cordon P.J., Romanini S., Salguero F.J., Nunez A., Bautista M.J., Jover A., and Gomez-Villamos J.C. Apoptosis of thymocytes related to cytokine expression in experimental classical swine fever. J. Comp. Pathol. 127 (2002) 239-248
39. Schwacha M.G., and Eisenstein T.K. Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium. Infect. Immun. 65 (1997) 4897-4903
40. Speiser D.E., Sebzda E., Ohteki T., Bachmann M.F., Pfeffer K., Mak T.W., and Ohashi P.S. Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo. Eur. J. Immunol. 26 (1996) 3055-3060
41. Sroller V., Kutinova L., Nemeckova S., Simonova V., and Vonka V. Effect of 3-beta-hydroxysteroid dehydrogenase gene deletion on virulence and immunogenicity of different vaccinia viruses and their recombinants. Arch. Virol. 143 (1998) 1311-1320
42. Tumpey T.M., Lu X., Morken T., Zaki S.R., and Katz J.M. Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans. J. Virol. 74 (2000) 6105-6116
43. Wilhelm S., Wagner H., and Hacker G. Activation of caspase-3-like enzymes in non-apoptotic T cells. Eur. J. Immunol. 28 (1998) 891-900
44. Wollenberg A., and Engler R. Smallpox, vaccination and adverse reactions to smallpox vaccine. Curr. Opin. Allergy Clin. Immunol. 4 (2004) 271-275
45. Wyatt L.S., Earl P.L., Eller L.A., and Moss B. Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 4590-4595
46. Xu R., Johnson A.J., Liggitt D., and Bevan M.J. Cellular and humoral immunity against vaccinia virus infection of mice. J. Immunol. 172 (2004) 6265-6271
47. Zacharchuk C.M., Mercep M., Chakraborti P.K., Simons Jr. S.S., and Ashwell J.D. Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic. J. Immunol. 145 (1990) 4037-4045