Foxp3 expression in cutaneous T-cell lymphocytic infiltrates

Journal of Cutaneous Pathology

Volumn 35, Issue 11, 2008, Pages 1032-1039

  Solomon, Garron J ^a   Magro, Cynthia M ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

ARTICLE; CUTANEOUS T CELL LYMPHOMA; DERMATOMYOSITIS; ECZEMA; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN TISSUE; HYPERSENSITIVITY REACTION; LICHENOID; LUPUS ERYTHEMATOSUS; MAJOR CLINICAL STUDY; PANNICULITIS; PIGMENTED PURPURIC DERMATOSIS; PITYRIASIS LICHENOIDES; PROTEIN EXPRESSION;

DERMATOMYOSITIS; FORKHEAD TRANSCRIPTION FACTORS; GRAFT VS HOST DISEASE; HUMANS; HYPERSENSITIVITY; IMMUNOENZYME TECHNIQUES; LEUKEMIC INFILTRATION; LUPUS ERYTHEMATOSUS, CUTANEOUS; LYMPHOMA, T-CELL; PITYRIASIS LICHENOIDES; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PURPURA; SKIN; T-LYMPHOCYTES, REGULATORY; TUMOR MARKERS, BIOLOGICAL;

EID: 53749101939     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2007.00969.x     Document Type: Article

References (29)

1. Walker LS. CD4+ CD25+ T reg: divide and rule? Immunology 2004 111 : 129.
2. Wraith DC, Nicolson KS, Whitley NT. Regulatory CD4+ T cells and the control of autoimmune disease. Curr Opin Immunol 2004 16 : 695.
3. Holm TL, Nielsen J, Claesson MH. CD4+CD25+ regulatory T cells: I. Phenotype and physiology. APMIS 2004 112 : 629.
4. Nielsen J, Holm TL, Claesson MH. CD4+CD25+ regulatory T cells: II. Origin, disease models and clinical aspects. APMIS 2004 112 : 642.
5. Danese S, Rutella S. The Janus face of CD4+CD25+ regulatory T cells in cancer and autoimmunity. Curr Med Chem 2007 14 : 649.
6. Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007 148 : 32.
7. Zhang L, Zhao Y. The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. J Cell Physiol 2007 211 : 590.
8. Taams LS, Smith J, Rustin MH, Salmon M, Poulter LW, Akbar AN. Human anergic/suppressive CD(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol 2001 31 : 1122.
9. Ziegler SF. FOXP3: of mice and men. Annu Rev Immunol 2006 24 : 209.
10. Behrens F, Himsel A, Rehart S, et al. Imbalance in distribution of functional autologous regulatory T cells in rheumatoid arthritis. Ann Rheum Dis 2007 66 : 1151.
11. Mudd PA, Teague BN, Farris AD. Regulatory T cells and systemic lupus erythematosus. Scand J Immunol 2006 64 : 211.
12. Alvarado-Sanchez B, Hernandez-Castro B, Portales-Perez D, et al. Regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2006 27 : 110.
13. Miyara M, Amoura Z, Parizot C, et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005 175 : 8392.
14. Ban Y, Tozaki T, Tobe T, et al. The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts. J Autoimmun 2007 28 : 201.
15. Wang W, Milani M, Ostlie N, et al. C57BL/6 mice genetically deficient in IL-12/IL-23 and IFN-gamma are susceptible to experimental autoimmune myasthenia gravis, suggesting a pathogenic role of non-Th1 cells. J Immunol 2007 178 : 7072.
16. Shevach EM, Di Paolo RA, Andersson J, et al. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev 2006 212 : 60.
17. Lopes JE, Soper DM, Ziegler SF. Foxp3 is required throughout the life of a regulatory T cell. Sci STKE 2007 393 : 36.
18. Terabe M, Berzofsky JA. Immunoregulatory T cells in tumor immunity. Curr Opin Immunol 2004 16 : 157.
19. Yang ZZ, Novak AJ, Ziesmer SC, Witzig TE, Ansell SM. Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma. Cancer Res 2006 66 : 10145.
20. Carreras J, Lopez-Guillermo A, Fox BC, et al. High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma. Blood 2006 108 : 2957.
21. Berger CL, Tigelaar R, Cohen J, et al. Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells. Blood 2005 105 : 1640.
22. Tiemessen MM, Mitchell TJ, Hendry L, Whittaker SJ, Taams LS, John S. Lack of suppressive CD4+CD25+FOXP3+ T cells in advanced stages of primary cutaneous T-cell lymphoma. J Invest Dermatol 2006 126 : 2217.
23. Klemke CD, Fritzsching B, Franz B, et al. Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas. Leukemia 2006 20 : 1123.
24. Roncador G, Garcia JF, Garcia JF, et al. FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma. Leukemia 2005 19 : 2247.
25. Yano H, Ishida T, Inagaki A, et al. Regulatory T-cell function of adult T-cell leukemia/lymphoma cells. Int J Cancer 2052 2007 : 120
26. Kohno T, Yamada Y, Akamatsu N, et al. Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells. Cancer Sci 2005 96 : 527.
27. Karube K, Ohshima K, Tsuchiya T, et al. Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells. Br J Haematol 2004 126 : 81.
28. Harnaha J, Machen J, Wright M, et al. Interleukin-7 is a survival factor for CD4+ CD25+ T-cells and is expressed by diabetes-suppressive dendritic cells. Diabetes 2006 55 : 158.
29. Yu A, Malek TR. Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+ T regulatory cells. J Immunol 2006 177 : 5115.