Bihemispheric reduction of GABA(A) receptor binding following focal cortical photothrombotic lesions in the rat brain

Brain Research

Volumn 813, Issue 2, 1998, Pages 374-380

  Qü, Meishu ^a   Buchkremer Ratzmann, Irmgard ^a   Schiene, Klaus ^a   Schroeter, Michael ^a   Witte, Otto W ^a   Zilles, Karl ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Cerebral ischemia; GABA(A) receptor; Paired pulse inhibition; Photothrombosis; Postlesional reaction; Receptor autoradiography

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; DIAGNOSTIC AGENT; FLUORESCENT DYE; MUSCIMOL; ROSE BENGAL; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN INJURY; CONTROLLED STUDY; HEMISPHERE; MALE; NERVE PROJECTION; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR DENSITY; ANIMAL; BRAIN CORTEX; BRAIN LEVEL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DOWN REGULATION; ELECTROPHYSIOLOGY; HEMISPHERIC DOMINANCE; METABOLISM; PATHOPHYSIOLOGY; PHOTOCHEMISTRY; PHYSIOLOGY; RADIOASSAY; THROMBOEMBOLISM; VASCULARIZATION; WISTAR RAT;

ANIMALS; BRAIN CHEMISTRY; CEREBRAL CORTEX; DOWN-REGULATION; ELECTROPHYSIOLOGY; FLUORESCENT DYES; FUNCTIONAL LATERALITY; GABA AGONISTS; INTRACRANIAL EMBOLISM AND THROMBOSIS; MALE; MUSCIMOL; PHOTOCHEMISTRY; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, GABA-A; ROSE BENGAL; TRITIUM;

EID: 0032494832     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01063-4     Document Type: Article

References (30)

1. Arckens L., Eysel U.T., Vanderhaeghen J.J., Orban G.A., Vandesande F. Effect of sensory deafferentation on the GABAergic circuitry of the adult cat visual system. Neuroscience. 83:1998;381-391.
2. Bidmon H.J., Oermann E., Schleicher A., Kato K., Kinscherf R., Buchkremer-Ratzmann I., Witte O.W., Zilles K. Copper-zinc superoxide dismutase and isolectin B4 binding are markers for associative and transhemispheric diaschisis induced by focal ischemia in rat cortex. Neurosci. Lett. 228:1997;163-166.
3. Bidmon H.J., Kato K., Schleicher A., Witte O.W., Zilles K. Transient increase of manganese-superoxide dismutase in remote brain areas after focal photothrombotic cortical lesion. Stroke. 29:1998;203-210.
4. Buchkremer-Ratzmann I., August M., Hagemann G., Witte O.W. Electrophysiological transcortical diaschisis after cortical photothrombosis in rat brain. Stroke. 27:1996;1105-1109.
5. I. Buchkremer-Ratzmann, M. August, G. Hagemann, O.W. Witte, Epileptiform discharges to extracellular stimuli in rat neocortical slice after photothrombotic infarction, J. Neurol. Sci. (1998) in press.
6. Buchkremer-Ratzmann I., Witte O.W. Pharmacological reduction of electrophysiological diaschisis after photothrombotic ischemia in rat neocortex. Eur. J. Pharmacol. 320:1997;103-109.
7. Bidmon H.J., Jancsik V., Schleicher A., Hagemann G., Witte O.W., Woodhamp T., Zilles K. Structural alterations and changes in cytoskeletal proteins and proteoglycans after focal cortical ischemia. Neuroscience. 82:1998;397-420.
8. Domann R., Hagemann G., Kraemer M., Freund H.J., Witte O.W. Electrophysiological changes in the surrounding brain tissue of photochemically induced cortical infarcts in the rat. Neurosci. Lett. 155:1993;69-72.
9. G. Hagemann, C. Redecker, T. Neumann-Haefelin, H.J. Freund, O.W. Witte, Increased long-term potentiation (LTP) in the surround of experimentally induced focal cortical infarction, Ann. Neurol. (1998) in press.
10. Hernandez T.D., Schallert T. Seizures and recovery from experimental brain damage. Exp. Neurol. 102:1988;318-324.
11. W.M. Jenkins, M.M. Merzenich, Reorganization of neocortical representation after brain injury: a neurophysiological model of the basis of recovery from stroke, in: F.J. Seil, E. Herbert, B.M. Carlson (Eds.), Progress in Brain Research, Vol. 71, Elsevier, Amsterdam, 1987, pp. 249-266.
12. Jones T.A., Schallert T. Use-dependent growth of pyramidal neurons after neocortical damage. J. Neurosci. 14:1994;2140-2152.
13. Kawamata T., Speliotes E.K., Finklestein S.P. The role of polypeptide growth factors in recovery from stroke. Adv. Neurol. 73:1997;377-382.
14. Kotila M., Waltimo O. Epilepsy after stroke. Epilepsy. 33:1992;495-498.
15. Lesage A.S., Peeters L., Leysen J.E. Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway. J. Pharmacol. Exp. Ther. 279:1996;759-766.
16. Merker B. Silver staining of cell bodies by means of physical development. J. Neurosci. Methods. 9:1983;235-241.
17. Mizukami K., Ikonomovic M.D., Mishizin A., Sheffield R., Grayson D.R., Armstrong D.M. Alterations of GABA(A)beta2/3 immunoreactivity in the dentate gyrus after perforant pathway lesion. NeuroReport. 8:1997;3379-3383.
18. A receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. 66:1995;507-521.
19. Nudo R.J. Remodeling of cortical motor representations after stroke, implications for recovery from brain damage. Mol. Psychiatry. 2:1997;188-191.
20. Pappius H.M. Cortical hypometabolism in injured brain: new correlations with the noradrenergic and serotonergic systems and with behavioral deficits. Neurochem. Res. 20(11):1995;1311-1321.
21. Qü M.S., Mittmann T., Luhmann H., Schleicher A., Zilles K. Long-term changes of ionotropic glutamate and GABA receptors after unilateral permanent focal cerebral ischemia in the mouse brain. Neuroscience. 85:1998;29-43.
22. Ralston H.J., Ohara P.T., Meng X.W., Wells J., Ralston D.D. Transneuronal changes of the inhibitory circuitry in the macaque somatosensory thalamus following lesions of the dorsal column nuclei. J. Comp. Neurol. 371:1996;325-335.
23. Reeves T.M., Zhu J., Povlishock J.T., Phillips L.L. The effect of combined fluid percussion and entorhinal cortical lesions on long-term potentiation. Neuroscience. 77:1997;431-444.
24. A-receptor expression in the surround of cerebral photothrombosis. J. Cereb. Blood Flow Metab. 16:1996;906-914.
25. 3H ]muscimol in the barrel field of mice after peripheral denervation: transient and long-lasting effects Exp. Brain Res. 100:1994;39-46.
26. Witte O.W., BuchkremerRatzmann I., Schiene K., Neumann-Haefelin T., Hagermann G., Kraemer M., Zilles K., Freund H.J. Lesion-induced network plasticity in remote brain areas. Trends Neurosci. 20:1997;348-349.
27. Witte O.W., Stoll G. Delayed and remote effects of focal cortical infarctions, secondary damage and reactive plasticity. Adv. Neurol. 73:1997;207-227.
28. B receptors, Europ. J. Neurosci. (1998) in press.
29. K. Zilles, A. Schleicher, Correlative imaging of transmitter receptor distributions in human cortex, in: W.E. Stumpf, H.F. Solomon (Eds.) Autoradiography and Correlative Imaging, San Diego, Academic Press, 1995, pp. 277-307.
30. K. Zilles, A. Wree, Cortex: Areal and laminar structure, in: G. Paxinos (Ed.), The Rat Nervous System, Academic Press, San Diego, 1995, pp. 649-685.