Lymphatic microvessel density and the expression of lymphangiogenic factors in oral squamous cell carcinoma

Medical Principles and Practice

Volumn 17, Issue 6, 2008, Pages 486-492

  Ali, Mohammad A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Lymphangiogenesis; Lymphangiogenic growth factors; Lymphatic microvessel density; Oral squamous cell carcinoma

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; SOMATOMEDIN B; SOMATOMEDIN C; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH VESSEL; LYMPHANGIOGENESIS; MALE; MICROVASCULATURE; MOUTH CARCINOMA; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FEMALE; FIBROBLAST GROWTH FACTOR 2; HEPATOCYTE GROWTH FACTOR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHANGIOGENESIS; LYMPHATIC VESSELS; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; PLATELET-DERIVED GROWTH FACTOR; SOMATOMEDINS; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 53549107480     PISSN: 10117571     EISSN: None     Source Type: Journal    
DOI: 10.1159/000151572     Document Type: Article

References (38)

1. Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K: Lymphangiogenesis and cancer metastasis. Nat Rev Cancer 2002;2:573-583.
2. Franchi A, Gallo O, Massi D, Baroni G, Santucci M: Tumor lymphangiogenesis in head and neck squamous cell carcinoma: a morphometric study with clinical correlations. Cancer 2004;101:973-978.
3. Dadras SS, Lange-Asschenfeldt B, Velasco P, Nguyen L, Vora A, Muzikansky A, Jahnke K, Hauschild A, Hirakawa S, Mihm MC, Detmar M: Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes. Mod Pathol 2005;18:1232-1242.
4. Gombos Z, Xu X, Chu CS, Zhang PJ, Acs G: Peritumoral lymphatic vessel density and vascular endothelial growth factor C expression in early-stage squamous cell carcinoma of the uterine cervix. Clin Cancer Res 2005;11:8364-8371.
5. Stacker SA, Caesar C, Baldwin ME, Thornton GE, Williams RA, Prevo R, Jackson DG, Nishikawa S, Kubo H, Achen MG: VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 2001;7:186-191.
6. Kubo H, Cao R, Brakenhielm E, Makinen T, Cao Y, Alitalo K: Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea. Proc Natl Acad Sci USA 2002;99:8868-8873.
7. Vincent L, Rafii S: Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis. Cancer Cell 2004;6:307-309.
8. Kajiya K, Hirakawa S, Ma B, Drinnenberg I, Detmar M: Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 2005;24:2885-2895.
9. Björndahl M, Cao R, Nissen LJ, Clasper S, Johnson LA, Xue Y, Zhou Z, Jackson D, Hansen AJ, Cao Y: Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo. Proc Natl Acad Sci USA 2005;102:15593-15598.
10. Sedivy R, Beck-Mannagetta J, Haverkampf C, Battistutti W, Honigschnabl S: Expression of vascular endothelial growth factor-C correlates with the lymphatic microvessel density and the nodal status in oral squamous cell cancer. J Oral Pathol Med 2003;32:455-460.
11. Björndahl MA, Religa P, Clasper S, Garvin S, Galter D, Meister B, Ikomi F, Tritsaris K, Dissing S, Ohhashi T, Jackson DG, Cao Y: PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 2004;6:333-345.
12. Kim CH, Moon SK, Bae JH, Lee JH, Han JH, Kim K, Choi EC: Expression of hepatocyte growth factor and c-Met in hypopharyngeal squamous cell carcinoma. Acta Otolaryngol 2006;126:88-94.
13. Wahi PN, Cohen B, Lutrha UK, Torloni H: Histological Typing of Oral and Oropharyngeal Tumours, ed 4. Geneva, WHO, 1971, pp 17-188.
14. Weidner N, Semple JP, Welch WR, Folkman J: Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
15. Schoppmann SF, Schindl M, Breiteneder-Geleff S, Soleima A, Breitenecker G, Karner B, Birner P: Inflammatory stromal reaction correlates with lymphatic microvessel density in early-stage cervical cancer. Anticancer Res 2001;21:3419-3423.
16. Karpanen T, Egeblad M, Karkkainen MJ, Kubo H, Ylä-Herttuala S, Jäättelä M, Alitalo K: Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001;61:1786-1790.
17. Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, Detmar M: VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 2005;201:1089-1099.
18. Ninck S, Reisser C, Dyckhoff G, Helmke B, Bauer H, Herold-Mende C: Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck. Int J Cancer 2003;106:34-44.
19. Chen YS, Wang JT, Chang YF, Liu BY, Wang YP, Sun A, Chiang CP: Expression of hepatocyte growth factor and c-met protein is significantly associated with the progression of oral squamous cell carcinoma in Taiwan. J Oral Pathol Med 2004;33:209-217.
20. Kahn HJ, Bailey D, Marks A: Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol 2002;15:434-440.
21. Xie ZJ, Yang XF, Fan J, Zhang YK, Wu QL, Gu ZY: The relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma. Zhonghua Kou Qiang Yi Xue Za Zhi 2004;39:221-223.
22. Miyahara M, Tanuma J, Sugihara K, Semba I: Tumor lymphangiogenesis correlates with lymph node metastasis and clinicopathologic parameters in oral squamous cell carcinoma. Cancer 2007;110:1287-1294.
23. Li C, Shintani S, Terakado N, Klosek SK, Ishikawa T, Nakashiro K, Hamakawa H: Microvessel density and expression of vascular endothelial growth factor, basic fibroblast growth factor, and platelet-derived endothelial growth factor in oral squamous cell carcinomas. Int J Oral Maxillofac Surg 2005;34:559-565.
24. Smith BD, Smith GL, Carter D, Sasaki CT, Haffty BG: Prognostic significance of vascular endothelial growth factor protein levels in oral and oropharyngeal squamous cell carcinoma. J Clin Oncol 2000;18:2046-2052.
25. Forootan SS, Ke Y, Jones AS, Helliwell TR: Basic fibroblast growth factor and angiogenesis in squamous carcinoma of the tongue. Oral Oncol 2000;36:437-443.
26. Wen Y, Yu D, Wang C, Li L, Wang X, Tang X, Fu F: Expression of VEGF-C and its correlation with cervical lymph nodes metastasis of oral cancers. Hua Xi Kou Qiang Yi Xue Za Zhi 2001;19:5-8.
27. Cao R, Björndahl MA, Gallego MI, Chen S, Religa P, Hansen AJ, Cao Y: Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action. Blood 2006;107:3531-3536.
28. Nakamura Y, Yasuoka H, Tsujimoto M, Imabun S, Nakahara M, Nakao K, Nakamura M, Mori I, Kakudo K: Lymph vessel density correlates with nodal status, VEGFC expression, and prognosis in breast cancer. Breast Cancer Res Treat 2005;91:125-132.
29. Kishimoto K, Sasaki A, Yoshihama Y, Mese H, Tsukamoto G, Matsumura T: Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma. Oral Oncol 2003;39:391-396.
30. Takada N, Yano Y, Matsuda T, Otani S, Osugi H, Higashino M, Kinoshita H, Fukushima S: Expression of immunoreactive human hepatocyte growth factor in human esophageal squamous cell carcinomas. Cancer Lett 1995;97:145-148.
31. Suzuki K, Cheng J, Watanabe Y: Hepatocyte growth factor and c-Met (HGF/c-Met) in adenoid cystic carcinoma of the human salivary gland. J Oral Pathol Med 2003;32:84-89.
32. Fukuura T, Miki C, Inoue T, Matsumoto K, Suzuki H: Serum hepatocyte growth factor as an index of disease status of patients with colorectal carcinoma. Br J Cancer 1998;78:454-459.
33. Tanaka K, Miki C, Wakuda R, Kobayashi M, Tonouchi H, Kusunoki M: Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma. Scand J Gastroenterol 2004;39:754-760.
34. Henriksen R, Funa K, Wilander E, Backstrom T, Ridderheim M, Oberg K: Expression and prognostic significance of plateletderived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res 1993;53:4550-4554.
35. Kawai T, Hiroi S, Torikata C: Expression in lung carcinomas of platelet-derived growth factor and its receptors. Lab Invest 1997;77:431-436.
36. Werner H, LeRoith D: The role of the insulin-like growth factor system in human cancer. Adv Cancer Res 1996;68:183-223.
37. Sohda M, Kato H, Miyazaki T, Nakajima M, Fukuchi M, Manda R, Fukai Y, Masuda N, Kuwano H: The role of insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in human esophageal cancer. Anticancer Res 2004;24:3029-3034.
38. Mita K, Nakahara M, Usui T: Expression of the insulin-like growth factor system and cancer progression in hormone-treated prostate cancer patients. Int J Urol 2000;7:321-329.