Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Ycells against amyloid-beta peptide-induced toxicity

NeuroReport

Volumn 19, Issue 15, 2008, Pages 1483-1486

  Tarozzi, Andrea ^a   Merlicco, Adriana ^a   Morroni, Fabiana ^a   Franco, Francesca ^a   Cantelli Forti, Giorgio ^a   Teti, Gabriella ^a   Falconi, Mirella ^a   Hrelia, Patrizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Alzheimer's disease; Amyloid beta peptide; Cyanidin 3 O glucoside; Neuroprotection; Protocatechuic acid

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; ANTHOCYANIN; CYANIDIN 3 O GLUCOPYRANOSIDE; NEUROPROTECTIVE AGENT; PROTOCATECHUIC ACID; THIOFLAVINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; TRANSMISSION ELECTRON MICROSCOPY;

AMYLOID BETA-PROTEIN; ANTHOCYANINS; APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; DRUG EVALUATION, PRECLINICAL; GLUCOSIDES; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; THIAZOLES;

EID: 53549106617     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32830fe4b8     Document Type: Article

References (22)

1. Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004; 430:631-639.
2. Findeis MA. The role of amyloid beta peptide 42 in Alzheimer's disease. Pharmacol Ther 2007; 116:266-286.
3. Liu Y, Dargusch R, Banh C, Miller CA, Schubert D. Detecting bioactive amyloid beta peptide species in Alzheimer's disease. J Neurochcm 2004; 91:648-656.
4. Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002; 416:535-539.
5. Glabe CG. Common mechanisms of amyloid oligomer pathogenesis in degenerative disease. Neurobiol Aging 2006; 27:570-575.
6. Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, et al. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci 2005; 8:79-84.
7. Wolfe MS. Therapeutic strategies for Alzheimer's disease. Nat Rev Drug Discov 2002; 1:859-866.
8. Andres-Lacueva C, Shukitt-Hale B, Galli RL, Jauregui O, Lamuela-Raventos RM, Joseph JA. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci 2005; 8:111-120.
9. Shin WH, Park SJ, Kim Ej. Protective effect of anthocyanins in middle cerebral artery occlusion and reperfusion model of cerebral ischemia in rats. Life Sci 2006; 79:130-137.
10. Tarozzi A, Morroni F, Hrelia S, Angeloni C, Marchesi A, Cantelli-Forti G, et al. Neuroprotective effects of anthocyanins and their in vivo metabolites in SH-SY5Y cells. Neurosci Lett 2007; 424:36-40.
11. Maezawa I, Hong HS, Wu HC, Battina SK, Rana S, Iwamoto T, et al. A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-beta oligomeric complexes. J Neurochem 2006; 98:57-67.
12. Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J Biol Client 2002; 277:32046-32053.
13. LeVine H. Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci 1993; 2:404-410.
14. Gupta VB, Rao KS. Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. Neurosci Lett 2007; 429:75-80.
15. Porat Y, Abramowitz A, Gazit E. Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism. Chem Biol Drug Des 2006; 67:27-37.
16. Gazit E. A possible role for pi-stacking in the self-assembly of amyloid fibrils. FASEB J 2002; 16:77-83.
17. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radie Biol Med 2000; 29:51-60.
18. Rauk A. Why is the amyloid beta peptide of Alzheimer's disease neurotoxic? Dalton Trans 2008; 14:1273-1282.
19. Wang SS, Rymer DL, Good TA. Reduction in cholesterol and sialic acid content protects cells from the toxic effects of beta-amyloid peptides. J Biol Chem 2001; 276:42027-42034.
20. Reinke AA, Gestwicki JE. Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: influence of linker length and flexibility. Chem Biol Drug Des 2007; 70:206-215.
21. Ramassamy C. Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. Eur J Pharmacol 2006; 545:51-64.
22. Williams CM, El Mohsen MA, Vauzour D, Rendeiro C, Butler LT, Ellis JA, et al. Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radie Biol Med 2008 [Epub ahead of print]