Interactions of interleukin-6 gene polymorphisms with calcium intake and physical activity on bone mass in pre-menarche Chinese girls

Osteoporosis International

Volumn 19, Issue 11, 2008, Pages 1629-1637

  Li, X ^a,b   He, G P ^a   Zhang, B ^a   Chen, Y M ^a   Su, Y X ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Institute of Health Inspection   (China)

Author keywords

Bone mineral density; Dietary calcium; Interaction; Interleukin 6 (IL 6); Physical activity; Polymorphism

Indexed keywords

INTERLEUKIN 6;

ARTICLE; BONE DENSITY; BONE MASS; BONE MINERAL; CALCIUM INTAKE; CONTROLLED STUDY; DNA POLYMORPHISM; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GENOTYPE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MENARCHE; NORMAL HUMAN; OUTCOME ASSESSMENT; PHYSICAL ACTIVITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHOOL CHILD;

BONE DENSITY; CALCIUM, DIETARY; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; FEMUR NECK; GENOTYPE; HIP JOINT; HUMANS; INTERLEUKIN-6; LUMBAR VERTEBRAE; MOTOR ACTIVITY; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC;

EID: 53549095692     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-008-0613-3     Document Type: Article

References (33)

1. EJ Samelson MT Hannan 2006 Epidemiology of osteoporosis Curr Rheumatol Rep 8 76 83
2. R Rizzoli JP Bonjour 1999 Determinants of peak bone mass and mechanisms of bone loss Osteoporos Int 9 S17 S23
3. YJ Liu H Shen P Xiao 2006 Molecular Genetic Studies of Gene Identification for Osteoporosis: A 2004 Update J Bone Miner Res 21 1511 1535
4. HW Deng MR Stegman KM Davies 1999 Genetic determination of variation and covariation of peak bone mass at the hip and spine J Clin Densitom 2 251 263
5. SC Manolagas 1998 The role of IL-6 type cytokines and their receptors in bone Ann N Y Acad Sci 840 194 204
6. SC Manolagas RL Jilka 1995 Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis New Engl J Med 332 305 311
7. N Ota T Nakajima I Nakazawa 2001 A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density J Hum Genet 46 267 272
8. P Garnero O Borel E Sornay-Rendu 2002 Association between a functional interleukin-6 gene polymorphism and peak bone mineral density and postmenopausal bone loss in women: the OFELY study Bone 31 43 50
9. LA Rubin GA Hawker VD Peltekova 1999 Determinants of peak bone mass: clinical and genetic analyses in a young female Canadian cohort J Bone Miner Res 14 633 643
10. SA Abrams IJ Griffin KM Hawthorne 2005 Vitamin D receptor Fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty J Bone Miner Res 20 945 953
11. SL Ferrari D Karasik J Liu 2004 Interactions of interleukin-6 promoter polymorphisms with dietary and lifestyle factors and their association with bone mass in men and women from the Framingham Osteoporosis Study J Bone Miner Res 19 552 559
12. I Kitagawa Y Kitagawa T Nagaya 2001 Interplay of physical activity and vitamin D receptor gene polymorphism on bone mineral density J Epidemiol 11 229 232
13. PR Crocker DA Bailey RA Faulkner 1997 Measuring general levels of physical activity: preliminary evidence for the Physical Activity Questionnaire for Older Children Med Sci Sports Exerc 29 1344 1349
14. BE Ainsworth WL Haskell AS Leon 1993 Compendium of physical activities: classification of energy costs of human physical activities Med Sci Sports Exerc 25 71 80
15. BE Ainsworth WL Haskell MC Whitt 2000 Compendium of physical activities: an update of activity codes and MET intensities Med Sci Sports Exerc 32 S498 S504
16. SL Ferrari P Garnero S Emond 2001 A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women Arthritis Rheum 44 196 201
17. SF Lei YZ Liu FY Deng 2005 Association and linkage analyses of interleukin-6 gene 634C/G polymorphism and bone phenotypes in Chinese J Bone Miner Metab 23 323 328
18. T Hayakawa T Takamura A Hisada 2002 IL-6 gene polymorphism -174G/C does not contribute substantially to hyperlipidaemia and Type II diabetes mellitus in Japanese men Diabetologia 45 453 454
19. R Zhai G Liu C Yang 2001 The G to C polymorphism at -174 of the interleukin-6 gene is rare in a Southern Chinese population Pharmacogenetics 11 699 701
20. HW Chung JS Seo SE Hur 2003 Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women J Hum Genet 48 243 248
21. Y Yamada F Ando N Niino 2003 Association of polymorphisms of interleukin-6, osteocalcin, and vitamin D receptor genes, alone or in combination, with bone mineral density in community-dwelling japanese women and men J Clin Endocrinol Metab 88 3372 3378
22. FY Deng JR Long SF Lei 2005 Potential effect of inter-genic action on peak bone mass (PBM) in Chinese females Acta Genetica Sinica 32 1003 1010
23. SF Lei YY Zhang FY Deng 2005 Bone mineral density and five prominent candidate genes in Chinese men: associations, interaction effects and their implications Maturitas 51 199 206
24. D Fishman G Faulds R Jeffery 1998 The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis J Clin Invest 102 1369 1376
25. A Kitamura G Hasegawa H Obayashi 2002 Interleukin-6 polymorphism (-634C/G) in the promotor region and the progression of diabetic nephropathy in type 2 diabetes Diabet Med 19 1000 1005
26. SL Ferrari L Ahn-Luong P Garnero 2003 Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women J Clin Endocrinol Metab 88 255 259
27. D Kamimura K Ishihara T Hirano 2003 IL-6 signal transduction and its physiological roles: the signal orchestration model Rev Physiol Biochem Pharmacol 149 1 38
28. PK Wong IK Campbell PJ Egan 2003 The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover Arthritis Rheum 48 1177 1189
29. RL Jilka G Hangoc G Girasole 1992 Increased osteoclast development after estrogen loss: mediation by interleukin-6 Science 257 88 91
30. JP Bonjour T Chevalley P Ammann 2001 Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study Lancet 358 1208 1212
31. T Winzenberg K Shaw J Fryer 2006 Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials BMJ 333 775 781
32. F Gori LC Hofbauer CR Dunstan 2000 The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated Endocrinology 141 4768 4776
33. RJ Shephard 2002 Cytokine responses to physical activity, with particular reference to IL-6: sources, actions, and clinical implications Crit Rev Immunol 22 165 182