Inflammatory bowel disease in rats: Bacterial and chemical interaction

World Journal of Gastroenterology

Volumn 14, Issue 25, 2008, Pages 4028-4039

  Hajj Hussein, Inaya Abdallah ^a,b   Tohme, Rania ^a   Barada, Kassem ^a   Mostafa, Mostafa Hassan ^b   Freund, Jean Noel ^c   Jurjus, Rosalyn A ^a   Karam, Walid ^d   Jurjus, Abdo ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b BEIRUT ARAB UNIVERSITY   (Lebanon)

^c INSERM   (France)

^d Institut National de Pathologie   (Lebanon)

Author keywords

Colitis; Escherichchia coli; Gastrointestinal inflammation; Inflammatory bowel disease model; Iodoacetamide

Indexed keywords

IODOACETAMIDE; METHYLCELLULOSE; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; MESSENGER RNA; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONICITY; COLON ULCER; CONTROLLED STUDY; DIARRHEA; DISEASE COURSE; ENTEROPATHOGENIC ESCHERICHIA COLI; ENZYME ACTIVITY; GENE EXPRESSION; HEMATOCHEZIA; HISTOPATHOLOGY; INOCULATION; MALE; NONHUMAN; PATHOPHYSIOLOGY; RAT; REPRODUCIBILITY; ULCERATIVE COLITIS; UPREGULATION; WEIGHT GAIN; ANIMAL; CHEMICALLY INDUCED DISORDER; DESCENDING COLON; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MICROBIOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; COLITIS, ULCERATIVE; COLON, DESCENDING; DISEASE MODELS, ANIMAL; ENTEROPATHOGENIC ESCHERICHIA COLI; IODOACETAMIDE; MALE; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 53449102210     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.4028     Document Type: Article

References (40)

1. Scaldaferri F, Fiocchi C. Inflammatory bowel disease: progress and current concepts of etiopathogenesis. J Dig Dis 2007; 8: 171-178
2. Campieri M, Gionchetti P. Bacteria as the cause of ulcerative colitis. Gut 2001; 48: 132-135
3. Rath HC. The role of endogenous bacterial flora: bystander or the necessary prerequisite? Eur J Gastroenterol Hepatol 2003; 15: 615-620
4. Rath HC. Role of commensal bacteria in chronic experimental colitis: lessons from the HLA-B27 transgenic rat. Pathobiology 2002; 70: 131-138
5. Nazli A, Yang PC, Jury J, Howe K, Watson JL, Soderholm JD, Sherman PM, Perdue MH, McKay DM. Epithelia under metabolic stress perceive commensal bacteria as a threat. Am J Pathol 2004; 164: 947-957
6. Schuppler M, Lotzsch K, Waidmann M, Autenrieth IB. An abundance of Escherichia coli is harbored by the mucosa-associated bacterial flora of interleukin-2-deficient mice. Infect Immun 2004; 72: 1983-1990
7. Yu J, Kaper JB. Cloning and characterization of the eae gene of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol 1992; 6: 411-417
8. Nougayrede JP, Fernandes PJ, Donnenberg MS. Adhesion of enteropathogenic Escherichia coli to host cells. Cell Microbiol 2003; 5: 359-372
9. Muza-Moons MM, Schneeberger EE, Hecht GA. Enteropathogenic Escherichia coli infection leads to appearance of aberrant tight junctions strands in the lateral membrane of intestinal epithelial cells. Cell Microbiol 2004; 6: 783-793
10. Hoffmann JC, Pawlowski NN, Kuhl AA, Hohne W, Zeitz M. Animal models of inflammatory bowel disease: an overview. Pathobiology 2002; 70: 121-130
11. Jurjus AR, Khoury NN, Reimund JM. Animal models of inflammatory bowel disease. J Pharmacol Toxicol Methods 2004; 50: 81-92
12. Macpherson AJ, Harris NL. Interactions between commensal intestinal bacteria and the immune system. Nat Rev Immunol 2004; 4: 478-485
13. Cash HL, Hooper LV. Commensal bacteria shape intestinal immune system development. ASM News 2005; 71: 77-83
14. Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation. Annu Rev Immunol 2002; 20: 495-549
15. Mayer L. The development of animal models of inflammatory bowel disease. Int Rev Immunol 2000; 19: 77-90
16. Satoh H, Sato F, Takami K, Szabo S. New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis. Jpn J Pharmacol 1997; 73: 299-309
17. Jurjus A, Barada K, Khoury N, Assef MD, Foltzer CJ, Reimund JM, Kedinger M. Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. Can J Physiol Pharmacol 2006; 84: 1191-1203
18. Szabo S, Trier JS, Frankel PW. Sulfhydryl compounds may mediate gastric cytoprotection. Science 1981; 214: 200-202
19. Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417-429
20. Dotan I, Mayer L. Immunopathogenesis of inflammatory bowel disease. Curr Opin Gastroenterol 2002; 18: 421-427
21. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989; 96: 795-803
22. Fabia R, Ar'Rajab A, Johansson ML, Willen R, Andersson R, Molin G, Bengmark S. The effect of exogenous administration of Lactobacillus reuteri R2LC and oat fiber on acetic acid-induced colitis in the rat. Scand J Gastroenterol 1993; 28: 155-162
23. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344-1350
24. Ishiguro Y. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol 1999; 34: 66-74
25. Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg 1998; 22: 382-389
26. Xia B, Crusius J, Meuwissen S, Pena A. Inflammatory bowel disease: definition, epidemiology, etiologic aspects, and immunogenetic studies. World J Gastroenterol 1998; 4: 446-458
27. Kusugami K, Fukatsu A, Tanimoto M, Shinoda M, Haruta J, Kuroiwa A, Ina K, Kanayarna K, Ando T, Matsuura T. Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent. Dig Dis Sci 1995; 40: 949-959
28. Farrell RJ, Peppercorn MA. Ulcerative colitis. Lancet 2002; 359: 331-340
29. Terashima S, Hoshino Y, Kanzaki N, Kogure M, Gotoh M. Ulcerative duodenitis accompanying ulcerative colitis. J Clin Gastroenterol 2001; 32: 172-175
30. Van Damme N, De Keyser F, Demetter P, Baeten D, Mielants H, Verbruggen G, Cuvelier C, Veys EM, De Vos M. The proportion of Th1 cells, which prevail in gut mucosa, is decreased in inflammatory bowel syndrome. Clin Exp Immunol 2001; 125: 383-390
31. Jankey N, Price LA. Small intestinal histochemical and histological changes in ulcerative colitis. Gut 1969; 10: 267-269
32. Perez-Navarro R, Ballester I, Zarzuelo A, Sanchez de Medina F. Disturbances in epithelial ionic secretion in different experimental models of colitis. Life Sci 2005; 76: 1489-1501
33. Fries W, Mazzon E, Squarzoni S, Martin A, Martines D, Micali A, Sturniolo GC, Citi S, Longo G. Experimental colitis increases small intestine permeability in therat. Lab Invest 1999; 79: 49-57
34. Goncalves NS, Ghaem-Maghami M, Monteleone G, Frankel G, Dougan G, Lewis DJ, Simmons CP, MacDonald TT. Critical role for tumor necrosis factor alpha in controlling the number of lumenal pathogenic bacteria and immunopathology in infectious colitis. Infect Immun 2001; 69: 6651-6659
35. Amati L, Caradonna L, Leandro G, Magrone T, Minenna M, Faleo G, Pellegrino NM, Jirillo E, Caccavo D. Immune abnormalities and endotoxemia in patients with ulcerative colitis and in their first degree relatives: attempts at neutralizing endotoxin-mediated effects. Curr Pharm Des 2003; 9: 1937-1945
36. Lu J, Wang A, Ansari S, Hershberg RM, McKay DM. Colonic bacterial superantigens evoke an inflammatory response and exaggerate disease in mice recovering from colitis. Gastroenterology 2003; 125: 1785-1795
37. Porras M, Martin MT, Soler M, Vergara P. Intestinal motor disorders associated with cyclical bacterial overgrowth in a rat model of enteritis. Am J Physiol Gastrointest Liver Physiol 2004; 287: G58-G64
38. Sasaki M, Sitaraman SV, Babbin BA, Gerner-Smidt P, Ribot EM, Garrett N, Alpern JA, Akyildiz A, Theiss AL, Nusrat A, Klapproth JM. Invasive Escherichia coli are a feature of Crohn's disease. Lab Invest 2007; 87: 1042-1054
39. Schulzke JD, Bojarski C, Zeissig S, Heller F, Gitter AH, Fromm M. Disrupted barrier function through epithelial cell apoptosis. Ann N Y Acad Sci 2006; 1072: 288-299
40. Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115: 182-205