Study of interaction between the polyoxidonium immunomodulator and the human immune system cells

International Immunopharmacology

Volumn 4, Issue 13, 2004, Pages 1615-1623

  Dyakonova, Vera A ^a   Dambaeva, Svetlana V ^a   Pinegin, Boris V ^a   Khaitov, Rakhim M ^a  

^a INSTITUTE OF IMMUNOLOGY   (Russian Federation)

Author keywords

Endocytosis; Hydrogen peroxide; Immunomodulator; Intracellular Ca 2+; Polyoxidonium

Indexed keywords

COLLOIDAL GOLD; CYTOKINE; DICHLOROFLUORESCEIN; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; HYDROGEN PEROXIDE; IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; PHORBOL 13 ACETATE 12 MYRISTATE; POLYOXIDONIUM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; DRUG BINDING; ELECTRON MICROSCOPY; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; LEUKOCYTE; LYMPHOCYTE; MONOCYTE; NEUTROPHIL; PHAGOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CALCIUM; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; GOLD COLLOID; HUMANS; HYDROGEN PEROXIDE; IMMUNE SYSTEM; IMMUNOLOGIC FACTORS; LYMPHOCYTES; MACROPHAGES; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON; MONOCYTES; NEUTROPHILS; ORGANIC CHEMICALS; PHAGOCYTES; POLYMERS; SPECTROMETRY, FLUORESCENCE; STAPHYLOCOCCUS AUREUS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS;

EID: 5344279117     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.07.015     Document Type: Article

References (34)

1. R.V. Petrov, R.M. Khaitov, A.V. Nekrasov, R.I. Ataullakhanov, B.V. Pinegin, and N.G. Puchkova Polyoxidonium, a new-generation immunomodulator: experience from a three-years clinical application Allergiya, Astma i Klinicheskaya Immunologiya Allergy, Asthma and Clinical Immunology 3 1999 3 6 [in Russian]
2. J.W. Goding Conjugation of antibodies with fluorochromes: modification to the standard methods J. Immunol. Methods 13 3-4 1976 215 226
3. S.W. Burchiel, B.S. Edwards, F.W. Kuckuck, F.T. Lauer, E.R. Prossnitz, and J.T. Ransom Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacological applications Methods 21 2000 221 230
4. D.A. Bass, J.W. Parce, L.R. Dechaitelet, P. Szejda, M.C. Seeds, and M. Thomas Flow cytometric studies of oxidative product formation by neurtophils: a graded response to membrane stimulation J. Immunol. 130 4 1983 1910 1917
5. S.F. Eeden, M.E. Klut, B.A.M. Walker, and J.C. Hogg The use of flow cytometry to measure neutrophil function J. Immunol. Methods 232 1999 23 43
6. A. Boyum Isolation of leukocytes from human blood. Further observations. Methylcellulose, dextran, and ficoll as erythrocyteaggregating agents Scand. J. Clin. Lab. Invest., Suppl. 97 1968 31 50
7. S.V. Dambaeva, D.V. Mazurov, N.M. Golubeva, V.A. D'yakonova, B.V. Pinegin, and R.M. Khaitov Effect of polyoxidonium on the phagocytic activity of human peripheral blood leukocytes Russ. J. Immunol. 8 1 2003 53 60
8. R.C. Goytia-Acevedo, M.E. Cebrian, and E.S. Calderon-Aranda Differential effects of arsenic on intracellular free calcium levels and the proliferative response of murine mitogen-stimulated lymphocytes Toxicology 189 3 2003 235 244
9. C.C. Silliman, D.J. Elzi, D.R. Ambruso, R.J. Musters, C. Hamiel, and R.J. Harbeck Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium J. Leukoc. Biol. 73 4 2003 511 524
10. D.J. Elzi, A.J. Bjornsen, T. MacKenzie, T.H. Wyman, and C.C. Silliman Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils Am. J. Physiol., Cell Physiol. 281 2001 C350 C360
11. M. Hamada, J. Honda, T. Yoshimuta, T. Fumimori, M. Okamoto, and H. Aizawa Fosfomycin inhibits neutrophil function via a protein kinase C-dependent signaling pathway Int. Immunopharmacol. 2 4 2002 511 518
12. S.R. Hall, and J. Rhodes Schiff base-mediated co-stimulation primes the T-cell-receptor-dependent calcium signalling pathway in CD4 T cells Immunology 104 1 2001 50 57
13. F. Marino, S. Cattaneo, M. Cosentino, E. Rasini, L. Di Grazia, and A. Fietta Diazepam stimulates migration and phagocytosis of human neutrophils: possible contribution of peripheral-type benzodiazepine receptors and intracellular calcium Pharmacology 63 1 2001 42 49
14. H. Zhang, C.D. Garlichs, A. Mugge, and W.G. Daniel Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils J. Physiol. 513 Pt. 2 1998 359 367
15. 2 by catalase Exp. Cell Res. 285 1 2003 146 158
16. G.D. Frank, M. Mifune, T. Inagami, M. Ohba, T. Sasaki, and S. Higashiyama Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta Mol. Cell. Biol. 23 5 2003 1581 1589
17. I.V. Gonchar, E.B. Burova, V.N. Dorosh, I.A. Gamalei, and N.N. Nikol'skii Dependence of EGF receptor and STAT factor activation on redox of A431 cells Tsitologiia 45 5 2003 478 487 [article in Russian]
18. E.L. Chan, and J.T. Murphy Reactive oxygen species mediate endotoxin-induced human dermal endothelial NF-kappaB activation J. Surg. Res. 111 1 2003 120 126
19. D. Kim, E. Cho, J. Seong, and H.-D. Um Adaptive concentration of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway J. Cell. Sci. 114 2001 4329 4334
20. M.A. Model, M.A. KuKuruga, and R.F. Todd 3rd A sensitive flow cytometryc method for measuring the oxidative burs J. Immunol. Methods 202 1997 105 111
21. J.A. Rosado, P.C. Redondo, G.M. Salido, E. Gomez-Arteta, S.O. Sage, and J.A. Pariente Hydrogen peroxide generation induces pp60src activation in human platelets: evidence for the involvement of this pathway in store-mediated calcium entry J. Biol. Chem. 279 3 2004 1665 1675
22. M. Aslan, and T. Ozben Oxidants in receptor tyrosine kinase signal transduction pathways Antioxid. Redox Signal. 5 6 2003 781 788
23. K. Hensley, K.A. Robinson, S.P. Gabbita, S. Salsman, and R.A. Floyd Reactive oxygen species, cell signaling, and cell injury Free Radic. Biol. Med. 28 10 2000 1456 1462
24. M. Gauthier, and D. Girard Activation of human neutrophils by chlordane: induction of superoxide production and phagocytosis but not chemotaxis or apoptosis Human Exp. Toxicol. 20 5 2001 229 235
25. A. Spagnoli, G.L. Spadoni, G. Sesti, D. Del Principe, D. Germani, and B. Boscherini Effect of insulin on hydrogen peroxide production by human polymorphonuclear leukocytes. Studies with monoclonal anti-insulin receptor antibodies, and an agonist and an inhibitor of protein kinase C Horm. Res. 43 6 1995 286 293
26. E. Junn, K. Lee, H. Ju, S. Han, J. Im, and H. Kang Requirement of hydrogen peroxide generation in TGF-β1 signal transduction in human lung fibroblast cells: involvement of hydrogen peroxide and Ca2+ in TGF-β1-induced IL-6 expression J. Immunol. 165 2000 2190 2197
27. H. Kamata, T. Manabe, S. Oka, K. Kamata, and H. Hirata Hydrogen peroxide activates IkappaB kinases through phosphorilation of serine residues in the activation loops FEBS Lett. 519 1-3 2002 231 237
28. Q. Li, S. Sanlioglu, S. Li, T. Ritchie, L. Oberley, and J.F. Engelhardt GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex Antioxid. Redox Signal. 3 3 2001 415 432
29. Y.M. Janssen-Heininger, M.E. Poynter, and P.A. Baeuerle Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB Free Radic. Biol. Med. 28 9 2000 1317 1327
30. A. Kelso Cytokines: principles and prospects Immunol. Cell Biol. 76 1998 300 317
31. R.B. Johnston Clinical aspects of chronic granulomatous disease Curr. Opin. Hematol. 8 1 2001 17 22
32. K. Zeman, M. Banasik, H. Scopczynska, L. Pokoca, and E. Bernatowska Contemporary diagnostics of chronic granulomatous disease Cent. Eur. J. Immunol. 25 3 2000 113 118
33. C.B. Chiwakata, C.J. Hemmer, and M. Dietrich High levels of inducible nitric oxide synthase mRNA are associated with increased monocyte counts in blood and have a beneficial role in Plasmodium falciparum malaria Infect. Immun. 68 1 2000 394 399
34. C. Jagannath, J.L. Actor, and R.L. Hunter Induction of nitric oxide in human monocytes and monocyte cell lines by Mycobacterium tuberculosis Nitric Oxide: Biology and Chemistry 2 3 1998 174 186