High levels of inducible nitric oxide synthase mRNA are associated with increased monocyte counts in blood and have a beneficial role in Plasmodium falciparum malaria

Infection and Immunity

Volumn 68, Issue 1, 2000, Pages 394-399

  Chiwakata, Collins Batsirai ^a   Hemmer, Christoph Josef ^a   Dietrich, Manfred ^a  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HOST PARASITE INTERACTION; HOST RESISTANCE; HUMAN; LEUKOCYTE COUNT; MALARIA FALCIPARUM; MONOCYTE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033961447     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.1.394-399.2000     Document Type: Article

References (38)

1. Agbenyega, T., B. Angus, G. Bedu-Addo, B. Baffoe-Bonnie, G. Griffin, P. Vallance, and S. Krishna. 1997. Plasma nitrogen oxides and blood lactate concentrations in Ghanaian children with malaria. Trans. R. Soc. Trop. Med. Hyg. 91:298-302.
2. Al-Yaman, F. M., B. Genton, and I. A. Clark. 1998. The ratio of reactive nitrogen intermediates to tumor necrosis factor and clinical outcome of falciparum malaria disease. Trans. R. Soc. Trop. Med. Hyg. 92:417-420.
3. Al Yaman, F. M., D. Mokela. B. Genton, K. A. Rockett, M. P. Alpers, and I. A. Clark. 1996. Association between serum levels of reactive nitrogen intermediates and coma in children with cerebral malaria in Papua New Guinea. Trans. R. Soc. Trop. Med. Hyg. 90:270-273.
4. Anstey, N. M., J. B. Weinberg, M. Y. Hassanali, E. D. Mwaikambo, D. Manyenga, M. Misukonis, D. R. Arnelle, D. Mollis, M. I. McDonald, and D. L. Granger. 1996. Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J. Exp. Med. 184:557-567.
5. Archer, S. 1993. Measurement of nitric oxide in biological models. FASEB J. 7:349-360.
6. Burgner, D., W. Xu, K. Rockett, M. Gravenor, I. G. Charles, A. V. Hill, and D. Kwiatkawski. 1998. Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet 352:1193-1194.
7. Chiwakata, C. B., G. Hort, C. J. Hemmer, and M. Dietrich. 1996. Sera from patients with falciparum malaria induce substance P gene expression in cultured human brain microvascular endothelial cells. Infect. Immun. 64: 5106-5110.
8. Chomcyznski, P., and N. Sacchi. 1987. Single step RNA isolation by acid guanidinium thiocyante-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
9. Clark, I. A., W. B. Cowden, and K. A. Rockett. 1993. Nitric oxide and cerebral malaria. Lancet 341:632-633.
10. Clark, I. A., W. B. Cowden, and K. A. Rockett. 1995. Nitric oxide in cerebral malaria. J. Infect. Dis. 171:1068-1069.
11. Clark, I. A., and K. A. Rockett. 1996. Nitric oxide and parasitic diseases. Adv. Parasitol. 37:1-55.
12. Clark, I. A., K. A. Rockett, and W. B. Cowden. 1991. Proposed link between cytokines, nitric oxide and human cerebral malaria. Parasitol. Today 7:205-207.
13. Clark, I. A., K. A. Rockett, and W. B. Cowden. 1992. Possible central role of nitric oxide in conditions clinically similar to cerebral malaria. Lancet 340: 894-896.
14. Cot, S., P. Ringwald, B. Mulder, P. Miailhes, J. Yap-Yap, A. K. Nussler, and W. M. C. Eling. 1994. Nitric oxide in cerebral malaria. J. Infect. Dis. 69: 1417-1418.
15. Duarte, M. I., C. E. Corbett, M. Boulos, and V. Amato Neto. 1985. Ultrastructure of the lung in falciparum malaria. Am. J. Trop. Med. Hyg. 34:31-35.
16. Estabrook, M. M., N. C. Christopher, J. M. Groffiss, C. J. Baker, and R. E. Mandrell. 1992. Sialylation and human neutrophil killing of group C Neisseria meningitidis. J. Infect. Dis. 166:1079-1088.
17. Geller, D. A., C. J. Lowenstein, R. A. Shapiro, A. K. Nussler, M. Di Silvio, S. C. Wang, D. K. Nakayama, R. L. Simmons, S. H. Synder, and T. R. Billiar. 1993. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc. Natl. Acad. Sci. USA 90:3491-3495.
18. Green, S. J., and C. A. Nacy. 1993. Antimicrobial and immunopathologic effects of cytokine-induced nitric oxide synthesis. Curr. Opin. Infect. Dis. 6:384-396.
19. James, S. L. 1995. Role of nitric oxide in parasitic infections. Microbiol. Rev. 59:533-547.
20. James, S. L., and J. Glaven. 1989. Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. J. lmmunol. 143:4208-4212.
21. Kremsner, P. G., S. Winkler, E. Wildling, et al. 1996. High plasma levels of nitrogen oxides are associated with severe disease and correlate with rapid parasitological and clinical cure in Plasmodium falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 90:44-47.
22. Kun, J. F., B. Mordmüller, B. Lell, L. G. Lehman, D. Luckner, and P. G. Kremsner. 1998. Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria. Lancet 351:265-266.
23. Lowenstein, C. J., C. S. Glatt, D. S. Bredt, and S. H. Synder. 1992. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc. Natl. Acad. Sci. USA 89:6711-6715.
24. Lyons, C. R., G. J. Orloff, and J. M. Cunningham. 1992. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267:6370-6374.
25. MacPherson, G. G., M. J. Warrell, N. J. White, S. Looareesuwan, and D. A. Warrell. 1985. Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. Am. J. Pathol. 119:385-401.
26. Mulder, B., S. Cot, P. Ringwald, P. Miailhes, J. Yap-Yap, A. Nussler, and W. Eling. 1995. The role of nitric oxide in cerebral malaria. Med. Trop. (Marseille) 55:114-115. (In French.)
27. Oo, M. M., M. Aikawa, T. Than, T. M. Aye, P. T. Myint, I. Igarashi, and W. C. Schoene. 1987. Human cerebral malaria: a pathological study. J. Neuropathol. Exp. Neurol. 46:223-231.
28. Porta, J., A. Carota, G. P. Pizzolato, E. Wildi, M. C. Widmer, C. Margairaz, and G. E. Grau. 1993. Immunopathological changes in human cerebral malaria. Clin. Neuropathol. 12:142-146.
29. Rockett, K. A., M. M. Awburn, B. B. Aggarwal, W. B. Cowden, and I. A. Clark. 1992. In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin and interleukin-1: possible role in malaria. Infect. Immun. 60: 3725-3730.
30. Ross, C. R., and P. Densen. 1985. Opsonophagocytosis of Neisseria gonorrhoeae: interaction of local and dessiminated isolates with complement and neutrophils. J. Infect. Dis. 151:33-41.
31. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
32. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
33. † T cells. J. Exp. Med. 180:353-358.
34. Senaldi, G., P. G. Kremsner, and G. E. Grau. 1992. Nitric oxide and cerebral malaria. Lancet 340:8834-8835.
35. Taylor-Robinson, A. W. 1997. Antimalarial activity of nitric oxide: cytostasis and cytotoxicity towards Plasmodium falciparum. Biochem. Soc. Trans. 25: 262S.
36. Taylor-Robinson, A. W., and M. Looker. 1998. Sensitivity of malaria parasites to nitric oxide at low oxygen tensions. Lancet 351:1630.
37. Weiss, G., P. E. Thuma, G. Mabeza, E. R. Werner, M. Herold, and V. R. Gordeuk. 1997. Modulatory potential of iron chelation therapy on nitric oxide formation. J. Infect. Dis. 175:226-230.
38. Xie, Q.-W., H. J. Cho, J. Calaycay, R. A. Mumford, K. M. Swiderek, T. D. Lee, A. Ding, T. Troso, and C. Nathan. 1992. Cloning and characterization of inducible nitric oxide from mouse macrophages. Science 256:225-228.