Induction of preneoplastic rat liver lesions with an attenuated p53 response by low doses of diethylnitrosamine

Archives of Toxicology

Volumn 78, Issue 9, 2004, Pages 540-548

  Silins, Ilona ^a   Stenius, Ulla ^a   Högberg, Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Carcinogenesis; Diethylnitrosamine; Dose response; p53; Preneoplastic enzyme altered foci

Indexed keywords

AFLATOXIN B1; CARCINOGEN; DIETHYLNITROSAMINE; PROTEIN P53;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; FEMALE; GENOTOXICITY; LIVER CANCER; LIVER CELL; NONHUMAN; PRECANCER; PRIORITY JOURNAL; RAT;

ANIMALS; DIETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; ISOENZYMES; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; NUCLEAR PROTEINS; PRECANCEROUS CONDITIONS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 5344253265     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-004-0570-3     Document Type: Article

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