Autonomic control of the aging heart

NeuroMolecular Medicine

Volumn 10, Issue 3, 2008, Pages 179-186

  Kaye, David M ^a   Esler, Murray D ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Heart failure; Human; Sympathetic nervous system

Indexed keywords

ADRENALIN; NORADRENALIN;

ADRENAL MEDULLA; ADRENERGIC SYSTEM; AGING; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CARDIOVASCULAR DISEASE; CENTRAL NERVOUS SYSTEM; HEART FAILURE; HEART INFARCTION; HEART RATE; HUMAN; HYPERTENSION; NERVE CONDUCTION; NERVE POTENTIAL; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; STROKE; SYMPATHETIC TONE; VAGUS NERVE STIMULATION; HEART; HEART DISEASE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; VAGUS NERVE;

AGING; AUTONOMIC NERVOUS SYSTEM; BAROREFLEX; HEART; HEART DISEASES; HEART RATE; HUMANS; HYPERTENSION; NOREPINEPHRINE; VAGUS NERVE;

EID: 53349179155     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12017-008-8034-1     Document Type: Article

References (41)

1. A. Aggarwal M. D. Esler 2001 Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure Journal of American College of Cardiology 37 1246 1251
2. A. Aggarwal M. D. Esler 2002 Norepinephrine turnover is increased in suprabulbar subcortical brain regions and is related to whole-body sympathetic activity in human heart failure Circulation 105 1031 1033
3. S. Akselrod D. Gordon 1985 Hemodynamic regulation: Investigation by spectral analysis American Journal of Physiology 249 H867 H875
4. M. A. Allessie P. A. Boyden 2001 Pathophysiology and prevention of atrial fibrillation Circulation 103 769 777
5. A. Arbab-Zadeh E. Dijk 2004 Effect of aging and physical activity on left ventricular compliance Circulation 110 1799 1805
6. M. Borton J. R. Docherty 1989 The effects of ageing on neuronal uptake of noradrenaline in the rat Naunyn Schmiedebergs Archives of Pharmacology 340 139 143
7. O. E. Brodde U. Konschak 1998 Cardiac muscarinic receptors decrease with age Journal of Clinical Investigation 101 471 478
8. C. M. Chang T. J. Wu 2001 Nerve sprouting and sympathetic hyperinnervation in a canine model of atrial fibrillation produced by prolonged right atrial pacing Circulation 103 22 25
9. R. E. De Meersman P. K. Stein 2007 Vagal modulation and aging Biological Psychology 74 165 173
10. M. Esler J. Hastings 2002 The influence of aging on the human sympathetic nervous system and brain norepinephrine turnover American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 282 R909 R916
11. M. Esler G. Jackman 1979 Determination of norepinephrine apparent release rate and clearance in humans Life Science 25 1461 1470
12. M. Esler G. Jennings 1990 Overflow of catecholamine neurotransmitters to the circulation: Source, fate, and functions Physiological Review 70 963 985
13. M. Esler D. Kaye 1995 Effects of aging on epinephrine secretion and regional release of epinephrine from the human heart The Journal of Clinical Endocrinology and Metabolism 80 435 442
14. M. D. Esler A. G. Turner 1995 Aging effects on human sympathetic neuronal function American Journal of Physiology 268 R278 R285
15. J. Fleg F. O'Connor 1995 Impact of age on the cardiovascular response todynamic upright exercise in healthy men and women Journal of Applied Physiology 78 890 900
16. P. A. Gould M. Yii 2006 Evidence for increased atrial sympathetic innervation in persistent human atrial fibrillation Pacing and Clinical Electrophysiology 29 821 829
17. G. Grassi M. Esler 1999 How to assess sympathetic activity in humans Journal of Hypertension 17 719 734
18. G. J. Hasking M. D. Esler 1986 Norepinephrine spillover to plasma in patients with congestive heart failure: Evidence of increased overall and cardiorenal sympathetic nervous activity Circulation 73 615 621
19. M. C. Irigoyen E. D. Moreira 2000 Aging and baroreflex control of RSNA and heart rate in rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 279 R1865 R1871
20. D. Kaye M. Esler 2005 Sympathetic neuronal regulation of the heart in aging and heart failure Cardiovascular Research 66 256 264
21. D. M. Kaye G. L. Jennings 1998 Differential effect of acute baroreceptor unloading on cardiac and systemic sympathetic tone in congestive heart failure Jorunal of the American College of Cardiology 31 583 587
22. D. M. Kaye G. W. Lambert 1994 Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure Jorunal of the American College of Cardiology 23 570 578
23. B. A. Kingwell J. M. Thompson 1994 Heart rate spectral analysis, cardiac norepinephrine spillover, and muscle sympathetic nerve activity during human sympathetic nervous activation and failure Circulation 90 234 240
24. M. T. La Rovere G. Specchia 1988 Baroreflex sensitivity, clinical correlates, and cardiovascular mortality among patients with a first myocardial infarction Circulation 78 816 824
25. G. W. Lambert C. Ferrier 1994 Monoaminergic neuronal activity in subcortical brain regions in essential hypertension Blood Press 3 55 66
26. F. H. Leenen E. Coletta 2005 Aging and cardiac responses to epinephrine in humans: Role of neuronal uptake American Journal of Physiology. Heart and Circulatory Physiology 288 H2498 H2503
27. W. N. Leimbach Jr. B. G. Wallin 1986 Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure Circulation 73 913 919
28. S. T. Li C. Holmes 2003 Aging-related changes in cardiac sympathetic function in humans, assessed by 6-18F-fluorodopamine PET scanning Journal of Nuclear Medicine 44 1599 1603
29. C. M. Masi L. C. Hawkley 2007 Respiratory sinus arrhythmia and disease of aging: Obesity, diabetes mellitus and hypertension Biological Psychology 74 212 223
30. I. T. Meredith A. Broughton 1991 Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias [see comments] The New England Journal of Medicine 325 618 624
31. K. Monahan 2007 Effect of aging on baroreflex function in humans American Journal of Physiology 293 R3 R12
32. K. Monahan F. Dinenno 2000 Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men Journal of Physiology 529 263 271
33. K. Narkiewicz B. G. Phillips 2005 Gender-selective interaction between aging, blood pressure, and sympathetic nerve activity Hypertension 45 522 525
34. M. Pagani F. Lombardi 1986 Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog Circulation Research 59 178 193
35. T. G. Pickering B. Gribbin 1972 Effects of autonomic blockade on the Baroreflex in man at rest and during exercise Circulation Research 30 177 185
36. U. Poller G. Nedelka 1997 Age-dependent changes in cardiac muscarinic receptor function in healthy volunteers Journal of American College of Cardiology 29 187 193
37. M. P. Schlaich E. Lambert 2004 Sympathetic augmentation in hypertension: Role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation Hypertension 43 169 175
38. D. R. Seals M. D. Esler 2000 Human ageing and the sympathoadrenal system Journal of Physiology 528 407 417
39. H. S. Smyth P. Sleight 1969 Reflex regulation of arterial pressure during sleep in man. A quantitative method of assessing baroreflex sensitivity Circulation Research 24 109 121
40. M. White F. H. Leenen 1994 Aging and cardiovascular responsiveness to beta-agonist in humans: Role of changes in beta-receptor responses versus baroreflex activity Clinical Pharmacology and Therapeutics 56 543 553
41. M. C. Wijffels C. J. Kirchhof 1995 Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats Circulation 92 1954 1968