Small animal bone biomechanics

Bone

Volumn 43, Issue 5, 2008, Pages 794-797

  Vashishth, Deepak ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Biomechanics; Bone; Fracture Toughness; Mice; Rat

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; BIOMECHANICS; BONE; EDITORIAL; FEMUR; FRACTURE; GENETIC ENGINEERING; GENETIC VARIABILITY; GEOMETRY; HUMERUS; INBRED STRAIN; LOADING TEST; LONG BONE; METATARSAL BONE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PHENOTYPE; RADIUS; RAT; SKELETON; TIBIA;

ANIMALS; BIOMECHANICS; BONE AND BONES; FRACTURES, BONE; HUMANS; IMAGING, THREE-DIMENSIONAL; MICE; STRESS, MECHANICAL; TENSILE STRENGTH;

EID: 53349165197     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.06.013     Document Type: Editorial

References (38)

1. Ng A.H., Wang S.X., Turner C.H., Beamer W.G., and Gr ynpas M.D. Bone quality and bone strength in BXH recombinant inbred mice. Calcif. Tissue Int. 81 3 (2007 Sep) 215-223
2. Tang B., Ngan A.H., and Lu W.W. An improved method for the measurement of mechanical properties of bone by nanoindentation. J. Mater. Sci. Mater. Med. 18 9 (2007) 1875-1881
3. Kavukcuoglu N.B., Denhardt D.T., Guzelsu N., and Mann A.B. Osteopontin deficiency and aging on nanomechanics of mouse bone. J. Biomed. Mater. Res. A. 83 1 (2007 Oct) 136-144
4. Akhter M.P., Fan Z., and Rho J.Y. Bone intrinsic material properties in three inbred mouse strains. Calcif. Tissue Int. 75 5 (2004 Nov) 416-420
5. McNamara L.M., Ederveen A.G., Lyons C.G., Price C., Schaffler M.B., Weinans H., et al. Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing. Bone 39 2 (2006 Aug) 392-400
6. Tang S.Y., Zeenath U., and Vashishth D. Effects of non-enzymatic glycation on cancellous bone fragility. Bone 40 4 (2007 Apr) 1144-1151
7. Tang, S.Y., Berard, G.P., Alkalay, R.N., Vashishth, D.. Micromechanical multicyclic creep tests show increased fragility of human cortical bone with age Transactions of the Orthopaedic Research Society, vol. 30, 2005 p. 335.
8. Ramasamy J.G., and Akkus O. Local variations in the micromechanical properties of mouse femur: the involvement of collagen fiber orientation and mineralization. J. Biomech. 40 4 (2007) 910-918
9. Wallace, J.M., Rajachar, R.M., Allen, M.R., Bloomfield, S.A., Robey, P.G., Young, M.F., et al. Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. Bone 40 4 (2007 Apr) 1120-1127
10. Silva M.J., Brodt M.D., Wopenka B., Thomopoulos S., Williams D., Wassen M.H., et al. Decreased collagen organization and content are associated with reduced strength of demineralized and intact bone in the SAMP6 mouse. J. Bone Miner. Res. 21 1 (2006 Jan) 78-88
11. Wergedal J.E., Ackert-Bicknell C.L., Tsaih S.W., Sheng M.H., Li R., Mohan S., et al. Femur mechanical properties in the F2 progeny of an NZB/B1NJ × RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. J. Bone Miner. Res. 21 8 (2006 Aug) 1256-1266
12. Maloul A., Rossmeier K., Mikic B., Pogue V., and Battaglia T. Geometric and material contributions to whole bone structural behavior in GDF-7-deficient mice. Connect. Tissue Res. 47 3 (2006) 157-162
13. Li C.Y., Schaffler M.B., Wolde-Semait H.T., Hernandez C.J., and Jepsen K.J. Genetic background influences cortical bone response to ovariectomy. J. Bone Miner. Res. 20 12 (2005 Dec) 2150-2158
14. Mousny M., Banse X., Wise L., Everett E.T., Hancock R., Vieth, R., et al. The genetic influence on bone susceptibility to fluoride. Bone 39 6 (2006 Dec) 1283-1289
15. Vashishth D. Hierarchy of bone microdamage at multiple length scales. Int. J. Fatigue 29 (2007) 1024-1033
16. George W., and Vashishth D. Damage mechanisms and failure modes of cortical bone under components of physiological loading. J. Orthop. Res. 23 5 (2005) 1047-1053
17. Boyce T.M., Fyhrie D.P., Glotkowski M.C., Radin E.L., and Schaffler M.B. Damage type and strain mode associations in human compact bone bending fatigue. J. Orthop. Res. 16 3 (1998 May) 322-329
18. Forwood M.R., and Parker A.W. Microdamage in response to repetitive torsional loading in the rat tibia. Calcif. Tissue Int. 45 1 (1989 Jul) 47-53
19. O'Brien F.J., Taylor D., and Clive Lee T. The effect of bone microstructure on the initiation and growth of microcracks. J. Orthop. Res. 23 2 (2005 Mar) 475-480
20. Bonfield W. Advances in the fracture mechanics of cortical bone. J. Biomech. 20 11-12 (1987) 1071-1081
21. Vashishth D., Behiri J., and Bonfield W. Crack growth resistance in cortical bone: concept of microcrack toughening. J. Biomech. 30 8 (1997) 763-769
22. Vashishth D. Rising crack growth resistance behavior in cortical bone: implications for toughness measurements. J. Biomech. 37 10 (2004) 943-946
23. Norman T.L., Nivargikar S.V., and Burr D.B. Resistance to crack growth in human cortical bone is greater in shear than in tension. J. Biomech. 29 8 (1996 Aug) 1023-1031
24. Wang X., and Agrawal C.M. Fracture toughness of bone using a compact sandwich specimen: effects of sampling sites and crack orientations. J. Biomed. Mater. Res. 33 1 (1996 Spring) 13-21
25. Zioupos P., and Currey J.D. Changes in the stiffness, strength, and toughness of human cortical bone with age. Bone 22 1 (1998 Jan) 57-66
26. Balooch G., Balooch M., Nalla R.K., Schilling S., Filvaroff E.H., Marshall, G.W., et al. TGF-beta regulates the mechanical properties and composition of bone matrix. Proc. Natl. Acad. Sci. U. S. A. 102 52 (2005 Dec 27) 18813-18818
27. Norman T.L., Vashishth D., and Burr D.B. Fracture toughness of human bone under tension. J. Biomech. 28 3 (1995 Mar) 309-320
28. Schriefer J.L., Robling A.G., Warden S.J., Fournier A.J., Mason J.J., and Turner C.H. A comparison of mechanical properties derived from multiple skeletal sites in mice. J. Biomech. 38 3 (2005 Mar) 467-475
29. Reilly G.C., and Currey J.D. The development of microcracking and failure in bone depends on the loading mode to which it is adapted. J. Exp. Biol. 202 Pt. 5 (1999 Mar) 543-552
30. Indrekvam K., Husby O.S., Gjerdet N.R., Engester L.B., and Langeland N. Age-dependent mechanical properties of rat femur. Measured in vivo and in vitro. Acta Orthop. Scand. 62 3 (1991 Jun) 248-252
31. Nalla R.K., Kinney J.H., and Ritchie R.O. Mechanistic fracture criteria for the failure of human cortical bone. Nat. Mater. 2 3 (2003 Mar) 164-168
32. Peterlik H., Roschger P., Klaushofer K., and Fratzl P. From brittle to ductile fracture of bone. Nat. Mater. 5 1 (2006 Jan) 52-55
33. Zioupos P., Currey J.D., and Sedman A.J. An examination of the micromechanics of failure of bone and antler by acoustic emission tests and laser scanning confocal microscopy. Med. Eng. Phys. 16 3 (1994 May) 203-212
34. Thompson J.B., Kindt J.H., Drake B., Hansma H.G., Morse D.E., and Hansma P.K. Bone indentation recovery time correlates with bond reforming time. Nature 414 6865 (2001 Dec 13) 773-776
35. Fantner G.E., Hassenkam T., Kindt J.H., Weaver J.C., Birkedal H., Pechenik, L., et al. Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nat. Mater. 4 8 (2005 Aug) 612-616
36. Yeni Y.N., and Fyhrie D.P. A rate-dependent microcrack-bridging model that can explain the strain rate dependency of cortical bone apparent yield strength. J. Biomech. 36 9 (2003 Sep) 1343-1353
37. Yan J., Mecholsky Jr. J.J., and Clifton K.B. How tough is bone? Application of elastic-plastic fracture mechanics to bone. Bone 40 2 (2007 Feb) 479-484
38. Ritchie R.O., Koester K.J., Ionova S., Yao W., Lane N.E., and Ager III J.W. Measurement of the toughness of bone: A tutorial with special reference to small animal studies. Bone 43 5 (2008 Nov) 798-812