Bone quality and bone strength in BXH recombinant inbred mice

Calcified Tissue International

Volumn 81, Issue 3, 2007, Pages 215-223

  Ng, A H M ^a   Wang, S X ^a   Turner, C H ^b   Beamer, W G ^c   Grynpas, M D ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b INDIANA UNIVERSITY   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

Architecture; Bone mineral density; Bone quality; Bone strength; Mineralization

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MINERALIZATION; BONE STRENGTH; BONE STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICAL BONE; FEMALE; FEMUR; GENE ISOLATION; GENETIC REGULATION; GENETIC TRAIT; GEOMETRY; HARDNESS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT INBRED STRAIN; STEM CELL; TRABECULAR BONE; VERTEBRA; VERTEBRA BODY;

ANIMALS; BIOMECHANICS; BONE DENSITY; CALCIFICATION, PHYSIOLOGIC; FEMALE; FEMUR; MICE; RECOMBINATION, GENETIC; SPINE;

EID: 34548500831     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-007-9047-8     Document Type: Article

References (16)

1. McKay HA, Bailey DA, Wilkinson AA, et al. (1994) Familial comparison of bone mineral density at the proximal femur and lumbar spine. Bone Miner 24:95-107
2. Pocock NA, Eisman JA, Hopper JL, et al. (1987) Genetic determinants of bone mass in adults: a twin study. J Clin Invest 80:706-710
3. Beamer WG, Donahue LR, Rosen CJ, Baylink DJ (1996) Genetic variability in adult bone density among inbred strains of mice. Bone 18:397-403
4. Taylor BA (1979) Established and incipient recombinant inbred strains of mice. In: Green MC (ed), Genetic Variants and Strains of the Laboratory Mice. Fischer, Stuttgart, p 397
5. Turner CH, Hsieh Y, Muller R, et al. (2000) Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Miner Res 15:1126-1131
6. Turner CH, Hsieh Y, Muller R, et al. (2001) Variation in bone biomechanical properties, microstructure, and density in BXH recombinant inbred mice. J Bone Miner Res 16:206-213
7. Nagy TR, Prince CW, Li J (2001) Validation of peripheral dual-energy X-ray absorptiometry for the measurement of bone mineral in intact and excised long bones of rats. J Bone Miner Res 16:1682-1687
8. Schenk RK, Olah AJ, Herrmann W (1984) Preparation of calcified tissues for light microscopy. In: Dickson GR (ed), Methods of Calcified Tissue Preparation. Elsevier, New York, pp 24-40
9. Parfitt AM, Drezner MK, Glorieux FH, et al. (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. J Bone Miner Res 10:149-156
10. Garrahan NJ, Mellish RW, Compston JE (1986) A new method for the two-dimensional analysis of bone structure in human iliac crest biopsies. J Microsc 142:341-349
11. Bracci PM, Bull SB, Grynpas MD (1988) Analysis of compositional bone density data using log ratio transformations. Biometrics 54:337-349
12. Currey JD (1990) Physical characteristics affecting the tensile failure properties of compact bone. J Biomech 23:837-844
13. Beamer WG, Shultz KL, Donahue LR, et al. (2001) Quantitative trait loci for femoral and lumber vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res 16:1195-1206
14. Bouxsein ML, Uchiyama T, Rosen CJ, et al. (2004) Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res 19:587-600
15. Judex S, Garman R, Squire M, et al. (2004) Genetically based influences on the site-specific regulation of trabecular and cortical bone morphology. J Bone Miner Res 19:600-606
16. Sheng MH, Baylink DJ, Beamer WG, et al. (2002) Regulation of bone volume is different in the metaphyses of the femur and vertebra of C3H/HeJ and C57BL/6J mice. Bone 30:486-491