-
1
-
-
0000286732
-
A minute chromosome in human granulocytic leukemia
-
Nowell PC, Hungerford DA. A minute chromosome in human granulocytic leukemia. Science 1960; 132: 1497.
-
(1960)
Science
, vol.132
, pp. 1497
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
2
-
-
0015694748
-
A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley JD. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining [letter]. Nature 1973; 243: 290-293.
-
(1973)
letter]. Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.D.1
-
3
-
-
53349097252
-
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myeloid leukemia
-
De Klein A, Geurts van Kessel A, Grosveld G, et al. A cellular oncogene is translocated to the Philadelphia chromosome in chronic myeloid leukemia. Nature 1982; 300: 290-293.
-
(1982)
Nature
, vol.300
, pp. 290-293
-
-
De Klein, A.1
Geurts van Kessel, A.2
Grosveld, G.3
-
4
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P2101bcr/abl gene of the Philadelphia chromosome
-
Daley GQ, Van Etten RA, Baltimore, D. Induction of chronic myelogenous leukemia in mice by the P2101bcr/abl gene of the Philadelphia chromosome. Science 1990; 247: 824-830.
-
(1990)
Science
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
Van Etten, R.A.2
Baltimore, D.3
-
5
-
-
23444462074
-
Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukaemia
-
The Italian Cooperative Study Group on Chronic Myeloid Leukemia
-
The Italian Cooperative Study Group on Chronic Myeloid Leukemia. Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukaemia. N Engl J Med 1994; 330: 820-825.
-
(1994)
N Engl J Med
, vol.330
, pp. 820-825
-
-
-
6
-
-
0027275074
-
Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts of chronic myeloid leukaemia patients after bone marrow transplantation
-
Cross NC, Feng L, Chase A, et al. Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts of chronic myeloid leukaemia patients after bone marrow transplantation. Blood 1993; 82: 1929-1936.
-
(1993)
Blood
, vol.82
, pp. 1929-1936
-
-
Cross, N.C.1
Feng, L.2
Chase, A.3
-
7
-
-
33646472776
-
Limited clinical value of regular bone marrow cytogenetic analysis in imatinib-treated chronic phase CML patients monitored by RQ-PCR for BCR-ABL
-
Ross DM, Branford S, Moore S, Hughes T. Limited clinical value of regular bone marrow cytogenetic analysis in imatinib-treated chronic phase CML patients monitored by RQ-PCR for BCR-ABL. Leukemia 2006; 20: 664-670.
-
(2006)
Leukemia
, vol.20
, pp. 664-670
-
-
Ross, D.M.1
Branford, S.2
Moore, S.3
Hughes, T.4
-
10
-
-
53349173718
-
-
accessed Jul 2008
-
Mayfield J. NEWCMLDRUG.COM [website]. http://www.newcmldrug.com/ (accessed Jul 2008).
-
COM [website]
-
-
-
11
-
-
10744233716
-
IRIS Investigators. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien SG, Guilhot F, Larson RA, et, al; IRIS Investigators. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003; 348: 994-1004.
-
(2003)
N Engl J Med
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
al4
-
12
-
-
33845444046
-
IRIS Investigators. Five-year follow-up of patients receiving imatinib for chronic myelaid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, et al; IRIS Investigators. Five-year follow-up of patients receiving imatinib for chronic myelaid leukemia. N Engl J Med 2006; 355: 2408-2417.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
-
13
-
-
34447544253
-
BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia
-
Schiffer CA. BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia. N Engl J Med 2007; 357: 258-265.
-
(2007)
N Engl J Med
, vol.357
, pp. 258-265
-
-
Schiffer, C.A.1
-
14
-
-
33646482407
-
Altered bone and mineral metabolism in patients receiving imatinib mesyiate
-
Berman E, Nicolaides M, Maki RG, et al. Altered bone and mineral metabolism in patients receiving imatinib mesyiate. N Engl J Med 2006; 354: 2006-2013.
-
(2006)
N Engl J Med
, vol.354
, pp. 2006-2013
-
-
Berman, E.1
Nicolaides, M.2
Maki, R.G.3
-
15
-
-
33644984905
-
Epidemiological analysis of second primary malignancies in more than 9500 patients treated with imatinib
-
Pilot PR, Sablinska K, Owen S, Hatfield A. Epidemiological analysis of second primary malignancies in more than 9500 patients treated with imatinib. Leukemia 2006; 20: 148.
-
(2006)
Leukemia
, vol.20
, pp. 148
-
-
Pilot, P.R.1
Sablinska, K.2
Owen, S.3
Hatfield, A.4
-
16
-
-
0142243204
-
Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during imatinib mesylate therapy in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase
-
Medina J, Kantarjian H, Talpaz M, et al. Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during imatinib mesylate therapy in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase. Cancer 2003; 98: 1905-1911.
-
(2003)
Cancer
, vol.98
, pp. 1905-1911
-
-
Medina, J.1
Kantarjian, H.2
Talpaz, M.3
-
17
-
-
4344638050
-
Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia
-
Terre C, Eclache V, Rousselot F, et al. Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia. Leukemia 2004; 18: 1340-1346.
-
(2004)
Leukemia
, vol.18
, pp. 1340-1346
-
-
Terre, C.1
Eclache, V.2
Rousselot, F.3
-
18
-
-
33750615550
-
Myelodysplastic syndromes and acute leukaemia developing after imatinib mesylate therapy for chronic myeloid leukaemia
-
Kovitz C, Kantargian H, Garcia-Manero G, et al, Myelodysplastic syndromes and acute leukaemia developing after imatinib mesylate therapy for chronic myeloid leukaemia. Blood 2006; 108: 2811-2813.
-
(2006)
Blood
, vol.108
, pp. 2811-2813
-
-
Kovitz, C.1
Kantargian, H.2
Garcia-Manero, G.3
-
19
-
-
34648833625
-
The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in Philadelphia-chromosome negative cells
-
Deininger MW, Cortes J, Paquette R, et al. The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in Philadelphia-chromosome negative cells. Cancer 2007; 110: 1509-1519.
-
(2007)
Cancer
, vol.110
, pp. 1509-1519
-
-
Deininger, M.W.1
Cortes, J.2
Paquette, R.3
-
20
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
Kerkela R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006; 12: 908-916.
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
-
21
-
-
34548030470
-
Congestive heart failure is a rare event in patients receiving imatinib therapy
-
Atallah E, Durand JB, Kantarjian H, Cortes J. Congestive heart failure is a rare event in patients receiving imatinib therapy. Blood 2007; 110: 1233-1237.
-
(2007)
Blood
, vol.110
, pp. 1233-1237
-
-
Atallah, E.1
Durand, J.B.2
Kantarjian, H.3
Cortes, J.4
-
22
-
-
53349097251
-
-
Rosti G. Case studies: pregnancy. Reproductive health and imatinib therapy [oral presentation]. CML Global Opinion Leader Summit. Practical Management of CML 2007: new options, new hope; 2007 Mar 2-4; Athens, Greece. http://www.cmlgolscme.com (accessed Jun 2008).
-
Rosti G. Case studies: pregnancy. Reproductive health and imatinib therapy [oral presentation]. CML Global Opinion Leader Summit. Practical Management of CML 2007: new options, new hope; 2007 Mar 2-4; Athens, Greece. http://www.cmlgolscme.com (accessed Jun 2008).
-
-
-
-
23
-
-
33746086705
-
Role of allogeneic stem cell transplantation for adult chronic myeloid leukemia in the imatinib era
-
Grigg A, Hughes T. Role of allogeneic stem cell transplantation for adult chronic myeloid leukemia in the imatinib era. Biol Blood Marrow Transplant 2006; 12: 795-807.
-
(2006)
Biol Blood Marrow Transplant
, vol.12
, pp. 795-807
-
-
Grigg, A.1
Hughes, T.2
-
24
-
-
29244433939
-
Higher dose imatinib (600 mg/ day) with selective intensification in newly diagnosed CML patients in chronic phase; cytogenetic response rates at 12 months are superior to IRIS [abstract]
-
Hughes T, Branford S, Reynolds J, et al. Higher dose imatinib (600 mg/ day) with selective intensification in newly diagnosed CML patients in chronic phase; cytogenetic response rates at 12 months are superior to IRIS [abstract]. Blood 2002; 104: 1001.
-
(2002)
Blood
, vol.104
, pp. 1001
-
-
Hughes, T.1
Branford, S.2
Reynolds, J.3
-
25
-
-
4644341516
-
Discontinuation of imatinib therapy after achieving a molecular response
-
Cortes J, O'Brien S, Kantarjian H. Discontinuation of imatinib therapy after achieving a molecular response. Blood 2004; 104: 2204-2205.
-
(2004)
Blood
, vol.104
, pp. 2204-2205
-
-
Cortes, J.1
O'Brien, S.2
Kantarjian, H.3
-
26
-
-
33846023983
-
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years
-
Rousselot P, Huguet F, Rea D, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years. Blood 2007; 109: 58-60.
-
(2007)
Blood
, vol.109
, pp. 58-60
-
-
Rousselot, P.1
Huguet, F.2
Rea, D.3
-
27
-
-
33644984830
-
Pregnancy among patients with chronic myeloid leukemia treated with imatinib
-
Ault P, Kantarjian H, O'Brien S, et al. Pregnancy among patients with chronic myeloid leukemia treated with imatinib. J Clin Oncol 2006; 24: 1204-1208.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1204-1208
-
-
Ault, P.1
Kantarjian, H.2
O'Brien, S.3
-
28
-
-
34547673400
-
Applying the discovery of the Philadelphia chromosome
-
Sherbenou DW, Druker BJ. Applying the discovery of the Philadelphia chromosome. J Clin Invest 2007; 117: 2067-2074.
-
(2007)
J Clin Invest
, vol.117
, pp. 2067-2074
-
-
Sherbenou, D.W.1
Druker, B.J.2
-
29
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293: 876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
30
-
-
33746934638
-
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib
-
Griswold IJ, MacPartlin M, Bumm T, et al. Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib. Mol Cell Biol 2006; 26: 6082-6093.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 6082-6093
-
-
Griswold, I.J.1
MacPartlin, M.2
Bumm, T.3
-
31
-
-
0141538143
-
SRC family kinases: Potential targets for the treatment of human cancer and leukemia
-
Warmuth M, Damoiseaux R, Liu Y, et al. SRC family kinases: potential targets for the treatment of human cancer and leukemia. Curr Pharm Des 2003; 9: 2043-2059.
-
(2003)
Curr Pharm Des
, vol.9
, pp. 2043-2059
-
-
Warmuth, M.1
Damoiseaux, R.2
Liu, Y.3
-
32
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006; 354: 2531-2541.
-
(2006)
N Engl J Med
, vol.354
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
33
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
Kantarjian H, Giles F, Wunderie L, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 2006; 354: 2542-2551.
-
(2006)
N Engl J Med
, vol.354
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderie, L.3
-
34
-
-
34249074686
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid ieukaemia after failure of first-line imatinib: A randomized phase 2 trial
-
Kantarjian H, Pasquini R, Hamerschlak N, et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid ieukaemia after failure of first-line imatinib: a randomized phase 2 trial. Blood 2007; 109: 5143-5150.
-
(2007)
Blood
, vol.109
, pp. 5143-5150
-
-
Kantarjian, H.1
Pasquini, R.2
Hamerschlak, N.3
-
35
-
-
33846240316
-
MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation
-
Giles FJ, Cortes J, Jones D, et al. MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation. Blood 2007; 109: 500-502.
-
(2007)
Blood
, vol.109
, pp. 500-502
-
-
Giles, F.J.1
Cortes, J.2
Jones, D.3
-
36
-
-
0036720397
-
The impact of clonal evolution on response to imatinib mesylate (ST1571) in accelerated phase CML
-
O'Dwyer ME, Mauro MJ, Kurilik G, et al. The impact of clonal evolution on response to imatinib mesylate (ST1571) in accelerated phase CML. Blood 2002; 100: 1628-1633.
-
(2002)
Blood
, vol.100
, pp. 1628-1633
-
-
O'Dwyer, M.E.1
Mauro, M.J.2
Kurilik, G.3
-
37
-
-
0037093092
-
Gleevec (imatinib mesylate) induces hematologic and cytogenetic responses in patients with chronic myeloid leukemia in myeloid blast crisis: Results of a phase II study
-
Sawyers CL, Hochhaus A, Feldman E, et al. Gleevec (imatinib mesylate) induces hematologic and cytogenetic responses in patients with chronic myeloid leukemia in myeloid blast crisis: results of a phase II study. Blood 2002; 99: 3530-3539.
-
(2002)
Blood
, vol.99
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
-
38
-
-
33745603988
-
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
-
Hughes T, Deininger M, Hochhaus A, et al. Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood 2006; 108: 28-37.
-
(2006)
Blood
, vol.108
, pp. 28-37
-
-
Hughes, T.1
Deininger, M.2
Hochhaus, A.3
-
39
-
-
33747154547
-
Evolving concepts in the management of chronic myeloid leukaemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
-
Baccarani M, Sagko G, Goldman J, et al. Evolving concepts in the management of chronic myeloid leukaemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2006; 108: 1809-1820.
-
(2006)
Blood
, vol.108
, pp. 1809-1820
-
-
Baccarani, M.1
Sagko, G.2
Goldman, J.3
-
40
-
-
8844261773
-
Long-term survival estimates for imatinib versus interferon-α plus low-dose cytarabine for patients with newly diagnosed chronic-phase chronic myeloid leukaemia
-
Anstrom KJ, Reed SD, Allen AS, et al. Long-term survival estimates for imatinib versus interferon-α plus low-dose cytarabine for patients with newly diagnosed chronic-phase chronic myeloid leukaemia. Cancer 2004; 101: 2584-2592.
-
(2004)
Cancer
, vol.101
, pp. 2584-2592
-
-
Anstrom, K.J.1
Reed, S.D.2
Allen, A.S.3
-
41
-
-
34548825795
-
BCR-ABL kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia
-
O'Hare T, Eide CA, Deininger MW. BCR-ABL kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia. Blood 2007; 110: 2242-2249.
-
(2007)
Blood
, vol.110
, pp. 2242-2249
-
-
O'Hare, T.1
Eide, C.A.2
Deininger, M.W.3
|