-
1
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-Kit and platelet-derived growth factor receptors
-
Buchdunger E, Cioffi CL, Law N, et al. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-Kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther. 2000;295:139-145.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.L.2
Law, N.3
-
2
-
-
10744228476
-
Efficacy of imatinib mesylate in the treatment of idiopathic hypereosinophilic syndrome
-
Cortes J, Ault P, Koller C, et al. Efficacy of imatinib mesylate in the treatment of idiopathic hypereosinophilic syndrome. Blood. 2003;101:4714-4716.
-
(2003)
Blood
, vol.101
, pp. 4714-4716
-
-
Cortes, J.1
Ault, P.2
Koller, C.3
-
3
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 2002;347:472-480.
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
von Mehren, M.2
Blanke, C.D.3
-
4
-
-
33644519834
-
Five year follow-up results of a phase II trial in patients with late chronic phase (L-CP) chronic myeloid leukemia (CML) treated with imatinib who are refractory/intolerant of interferon-{alpha} [abstract]
-
Gambacorti C, Talpaz M, Sawyers CL, et al. Five year follow-up results of a phase II trial in patients with late chronic phase (L-CP) chronic myeloid leukemia (CML) treated with imatinib who are refractory/intolerant of interferon-{alpha} [abstract]. Blood. 2005;106:1089a.
-
(2005)
Blood
, vol.106
-
-
Gambacorti, C.1
Talpaz, M.2
Sawyers, C.L.3
-
5
-
-
2942567555
-
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate
-
Thomas DA, Faderl S, Cortes J, et al. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood. 2004;103:4396-4407.
-
(2004)
Blood
, vol.103
, pp. 4396-4407
-
-
Thomas, D.A.1
Faderl, S.2
Cortes, J.3
-
6
-
-
33644845774
-
High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia: A phase II study by the Japan Adult Leukemia Study Group
-
Yanada M, Takeuchi J, Sugiura I, et al. High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia: a phase II study by the Japan Adult Leukemia Study Group. J Clin Oncol. 2006;24:460-466.
-
(2006)
J Clin Oncol
, vol.24
, pp. 460-466
-
-
Yanada, M.1
Takeuchi, J.2
Sugiura, I.3
-
7
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006;355:2408-2417.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
-
8
-
-
25444484658
-
Imatinib for the treatment of pulmonary arterial hypertension
-
Ghofrani HA, Seeger W, Grimminger F. Imatinib for the treatment of pulmonary arterial hypertension. N Engl J Med. 2005;353:1412-1413.
-
(2005)
N Engl J Med
, vol.353
, pp. 1412-1413
-
-
Ghofrani, H.A.1
Seeger, W.2
Grimminger, F.3
-
10
-
-
11344291101
-
Food and Drug Administration drug approval summary: Conversion of imatinib mesylate (STI571; Gleevec) tablets from accelerated approval to full approval
-
Cohen MH, Johnson JR, Pazdur R. U.S. Food and Drug Administration drug approval summary: conversion of imatinib mesylate (STI571; Gleevec) tablets from accelerated approval to full approval. Clin Cancer Res. 2005;11:12-19.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 12-19
-
-
Cohen, M.H.1
Johnson, J.R.2
Pazdur, R.U.S.3
-
11
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
Kerkela R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med. 2006;12:908-916.
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
-
13
-
-
33749159996
-
Recent insights into cardiac hypertrophy and left ventricular remodeling
-
Kerkela R, Force T. Recent insights into cardiac hypertrophy and left ventricular remodeling. Curr Heart Fail Rep. 2006;3:14-18.
-
(2006)
Curr Heart Fail Rep
, vol.3
, pp. 14-18
-
-
Kerkela, R.1
Force, T.2
-
14
-
-
33644982754
-
Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats
-
Schellings MW, Baumann M, van Leeuwen RE, et al. Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats. Hypertension. 2006;47:467-474.
-
(2006)
Hypertension
, vol.47
, pp. 467-474
-
-
Schellings, M.W.1
Baumann, M.2
van Leeuwen, R.E.3
-
15
-
-
0037058826
-
Lifetime risk for developing congestive heart failure: The Framingham heart study
-
Lloyd-Jones DM, Larson MG, Leip EP, et al. Lifetime risk for developing congestive heart failure: the Framingham heart study. Circulation. 2002;106:3068-3072.
-
(2002)
Circulation
, vol.106
, pp. 3068-3072
-
-
Lloyd-Jones, D.M.1
Larson, M.G.2
Leip, E.P.3
-
16
-
-
33644849222
-
Heart disease and stroke statistics - 2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics - 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113:e85-e151.
-
(2006)
Circulation
, vol.113
-
-
Thom, T.1
Haase, N.2
Rosamond, W.3
-
17
-
-
0030002580
-
The progression from hypertension to congestive heart failure
-
Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996;275:1557-1562.
-
(1996)
JAMA
, vol.275
, pp. 1557-1562
-
-
Levy, D.1
Larson, M.G.2
Vasan, R.S.3
Kannel, W.B.4
Ho, K.K.5
-
18
-
-
33745894642
-
-
From AM, Leibson CL, Bursi F, et al. Diabetes in heart failure: prevalence and impact on outcome in the population. Am J Med. 2006;119:591-599.
-
From AM, Leibson CL, Bursi F, et al. Diabetes in heart failure: prevalence and impact on outcome in the population. Am J Med. 2006;119:591-599.
-
-
-
-
19
-
-
33644590228
-
Fatal cardiomyopathy associated with pegylated interferon/ribavirin in a patient with chronic hepatitis C
-
Condat B, Asselah T, Zanditenas D, et al. Fatal cardiomyopathy associated with pegylated interferon/ribavirin in a patient with chronic hepatitis C. Eur J Gastroenterol Hepatol. 2006;18:287-289.
-
(2006)
Eur J Gastroenterol Hepatol
, vol.18
, pp. 287-289
-
-
Condat, B.1
Asselah, T.2
Zanditenas, D.3
-
20
-
-
21444434751
-
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia
-
Harrison CN, Campbell PJ, Buck G, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med. 2005;353:33-45.
-
(2005)
N Engl J Med
, vol.353
, pp. 33-45
-
-
Harrison, C.N.1
Campbell, P.J.2
Buck, G.3
-
21
-
-
0032563825
-
Doxorubicin-induced cardiomyopathy
-
Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med. 1998;339:900-905.
-
(1998)
N Engl J Med
, vol.339
, pp. 900-905
-
-
Singal, P.K.1
Iliskovic, N.2
-
22
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-652.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
-
23
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase 2 study
-
Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase 2 study. Blood. 2002;99:3530-3539.
-
(2002)
Blood
, vol.99
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
-
24
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood. 2002;99:1928-1937.
-
(2002)
Blood
, vol.99
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.J.3
-
25
-
-
33644830094
-
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme
-
Reardon DA, Egorin MJ, Quinn JA, et al. Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. J Clin Oncol. 2005;23:9359-9368.
-
(2005)
J Clin Oncol
, vol.23
, pp. 9359-9368
-
-
Reardon, D.A.1
Egorin, M.J.2
Quinn, J.A.3
-
26
-
-
0037105560
-
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
-
Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood. 2002;100:1965-1971.
-
(2002)
Blood
, vol.100
, pp. 1965-1971
-
-
Ottmann, O.G.1
Druker, B.J.2
Sawyers, C.L.3
-
27
-
-
33646268037
-
Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: Significant toxicity with no clinical efficacy
-
Wyman K, Atkins MB, Prieto V, et al. Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: significant toxicity with no clinical efficacy. Cancer. 2006;106:2005-2011.
-
(2006)
Cancer
, vol.106
, pp. 2005-2011
-
-
Wyman, K.1
Atkins, M.B.2
Prieto, V.3
-
28
-
-
78650211980
-
Declining rates of adverse events (AEs), rare occurrence of serious AEs (SAEs), and no unexpected long-term side effects at 5 years in patients with newly diagnosed chronic myeloid leukemia (CML) in chronic phase (CP) initially treated with imatinib (IM) in the International Randomized Study of Interferon vs STI571 (IRIS) [abstract]
-
Kantarjian HM, Larson RA, Guilhot F, et al. Declining rates of adverse events (AEs), rare occurrence of serious AEs (SAEs), and no unexpected long-term side effects at 5 years in patients with newly diagnosed chronic myeloid leukemia (CML) in chronic phase (CP) initially treated with imatinib (IM) in the International Randomized Study of Interferon vs STI571 (IRIS) [abstract]. Blood. 2006;108:2136a.
-
(2006)
Blood
, vol.108
-
-
Kantarjian, H.M.1
Larson, R.A.2
Guilhot, F.3
-
29
-
-
33846091260
-
In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]
-
Hatfield A, Owen S, Pilot PR. In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]. Nat Med. 2007;13:13.
-
(2007)
Nat Med
, vol.13
, pp. 13
-
-
Hatfield, A.1
Owen, S.2
Pilot, P.R.3
-
30
-
-
33846059080
-
In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]
-
Rosti G, Martinelli G, Baccarani M. In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]. Nat Med. 2007;13:15.
-
(2007)
Nat Med
, vol.13
, pp. 15
-
-
Rosti, G.1
Martinelli, G.2
Baccarani, M.3
-
31
-
-
33846070788
-
In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]
-
Gambacorti C, Tornaghi L, Franceschino A, et al. In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]. Nat Med. 2007;13:13-14.
-
(2007)
Nat Med
, vol.13
, pp. 13-14
-
-
Gambacorti, C.1
Tornaghi, L.2
Franceschino, A.3
-
32
-
-
33846086176
-
In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]
-
Atallah E, Kantarjian H, Cortes J. In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate" [letter]. Nat Med. 2007;13:14-16.
-
(2007)
Nat Med
, vol.13
, pp. 14-16
-
-
Atallah, E.1
Kantarjian, H.2
Cortes, J.3
|