Power of genetic association studies in the presence of linkage disequilibrium and allelic heterogeneity

Human Heredity

Volumn 66, Issue 4, 2008, Pages 210-222

  Fisher, Sheila A ^a   Lewis, Cathryn M ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

Allelic association; Allelic heterogeneity; Case control study; Heterogeneity; Linkage disequilibrium; Mutations; Sample size; Transmission disequilibrium test

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15;

ALLELE; ARTICLE; CASE CONTROL STUDY; DOMINANT INHERITANCE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC MARKER; GENETIC MODEL; GENOTYPE; HUMAN; NOD2 GENE; PTPN22 GENE; RECESSIVE INHERITANCE; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; CROHN DISEASE; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MUTATION; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; SAMPLE SIZE;

EID: 53249129077     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000143404     Document Type: Article

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