Structural consequences of nucleophosmin mutations in acute myeloid leukemia

Journal of Biological Chemistry

Volumn 283, Issue 34, 2008, Pages 23326-23332

  Grummitt, Charles G ^a   Townsley, Fiona M ^a   Johnson, Christopher M ^a   Warren, Alan J ^b,c   Bycroft, Mark ^a  

^a MRC CENTRE FOR PROTEIN ENGINEERING   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANTS (BOTANY); PORT TERMINALS;

ACUTE MYELOID LEUKEMIAS; C TERMINUSES; DISTINCTIVE FEATURES; DO-MAINS; GLOBULAR DOMAINS; LEUKEMIC CELLS; LYSINE RESIDUES; MOLECULAR MECHANISMS; MUTANT PHENOTYPES; NMR SPECTROSCOPIES; NUCLEAR EXPORT SIGNALS; NUCLEOLAR LOCALIZATIONS; NUCLEOPHOSMIN; SMALL MOLECULES; STRUCTURAL CONSEQUENCES; TERMINAL DOMAINS; TERMINAL RESIDUES; TRYPTOPHAN RESIDUES; TUMOR SUPPRESSORS;

AMINO ACIDS;

LYSINE; MUTANT PROTEIN; NUCLEOPHOSMIN; NUCLEAR PROTEIN; TRYPTOPHAN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOPLASM; GENE; GENE MUTATION; MOUSE; NONHUMAN; NPM1 GENE; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR MAGNETIC RESONANCE; NUCLEOLUS; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CELL NUCLEOLUS; CELL PROLIFERATION; CYTOPLASM; HUMANS; LEUKEMIA, MYELOID, ACUTE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; TRYPTOPHAN;

EID: 53149137462     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801706200     Document Type: Article

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