Improving the productivity of single-chain Fv antibody against c-Met by rearranging the order of its variable domains

Journal of Microbiology and Biotechnology

Volumn 18, Issue 6, 2008, Pages 1186-1190

  Kim, Yu Jin ^a   Neelamegam, Rameshkumar ^a   Heo, Mi Ae ^a   Edwardraja, Selvakumar ^a   Paik, Hyun Jong ^a   Lee, Sun Gu ^a  

^a Pusan National University   (South Korea)

Author keywords

Anti c Met scFv; Diabody; Domain order; Variable domain

Indexed keywords

SCATTER FACTOR RECEPTOR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; BISPECIFIC ANTIBODY; CANCER ANTIBODY; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; GENE DELETION; GENE MUTATION; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PURIFICATION; ANTIBODY AFFINITY; ENZYME SPECIFICITY; GENETICS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR CLONING; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI;

ANTIBODIES, BISPECIFIC; ANTIBODIES, NEOPLASM; ANTIBODY AFFINITY; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MET; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 53149136274     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: None     Document Type: Article

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